Tag: 300-400

Effects of TO-125 (benorilate) on the central nervous system was written by Fujita, Mitsunobu;Ishii, Makoto;Shibuya, Takeshi. And the article was included in Tokyo Ika Daigaku Zasshi in 1978.Safety of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

TO-125 (I) [5003-48-5], an analgesic drug, administered orally to rabbits at 500 mg/kg slightly inhibited spontaneous elec. activity in the brain but had no significant effect on the central nervous system. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Safety of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The study on the synthesis of benorilate was written by Teng, Xiao-bo;Qian, Jie. And the article was included in Shandong Huagong in 2009.Application of 5003-48-5 The following contents are mentioned in the article:

A review with 13 references Benorilate is a good non-steroidal antipyretic analgesics, product of structurally modified ester of aspirin and N-acetyl-p-aminophenol. The methods of synthesis of benorilate were reviewed. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Application of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Stereoselective Preparation of C-Aryl Glycosides via Visible-Light-Induced Nickel-Catalyzed Reductive Cross-Coupling of Glycosyl Chlorides and Aryl Bromides was written by Mou, Ze-Dong;Wang, Jia-Xi;Zhang, Xia;Niu, Dawen. And the article was included in Advanced Synthesis & Catalysis in 2021.Reference of 604-69-3 The following contents are mentioned in the article:

A nickel-catalyzed cross-coupling reaction of glycosyl chlorides with aryl bromides has been developed. The reaction proceeds smoothly under visible-light irradiation and features the use of bench-stable glycosyl chlorides, allowing the highly stereoselective synthesis of C-aryl glycosides. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Reference of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Reference of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Combination of TLC, GLC (OV 1 and OV 17) and HPLC (RP 18) for a rapid detection of drugs, intoxicants and related compounds was written by Daldrup, T.;Susanto, F.;Michalke, P.. And the article was included in Fresenius’ Zeitschrift fuer Analytische Chemie in 1981.Formula: C17H15NO5 The following contents are mentioned in the article:

Relative retention times for 570 drugs and related compounds on 8 chromatog. systems were reported. TLC employing silica gel plates, gas chromatog. employing 3% OV-1 on Chromosorb W-HP, and reversed-phase high-pressure chromatog. employing octadecylsilanized columns were described. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Formula: C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Determination of benorylate and its impurities by RP-HPLC was written by Chao, Ruobing;Chen, Tao;Ding, Shizhi. And the article was included in Yaoxue Xuebao in 1999.Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

The contents of benorylate, and of its related substances paracetamol, acetyl paracetamol, aspirin, salicylic acid and salophen, and its impurities were determined by RP-HPLC at 240 nm on an ODS column with MeOH-H₂O (56:44, pH 3.5) as the mobile phase. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Contribution to the microscopic characterization and identification of drugs. Part 12 was written by Kuhnert-Brandstaetter, Maria;Boesch, L.;Eckstein, G.. And the article was included in Scientia Pharmaceutica in 1978.SDS of cas: 5003-48-5 The following contents are mentioned in the article:

Morpholog., crystallog., and other physicochem. properties of 50 common drugs were determined under thermomicroscope. Data in relation to m.p., eutectic temperatures with various compounds, glass powder indexes, red and Na light temperatures were tabulated. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5SDS of cas: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.SDS of cas: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glycosylation with 3,5-Dimethyl-4-(2′-phenylethynylphenyl)phenyl (EPP) Glycosides via a Dearomative Activation Mechanism was written by Hu, Zhifei;Tang, Yu;Yu, Biao. And the article was included in Journal of the American Chemical Society in 2019.Safety of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

A highly effective and versatile glycosylation method is developed, which uses 3,5-dimethyl-4-(2′-phenylethynylphenyl)phenyl (EPP) glycosides as donors and NIS/TMSOTf as promoter and proceeds via an unprecedented dearomative activation mechanism. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Safety of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Safety of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A facile, catalytic and environmentally benign method for esterification of carboxylic acids and transesterification of carboxylic esters with nearly equimolar amounts of alcohols was written by Bose, D. Subhas;Satyender, Apuri;Das, A. P. Rudra;Mereyala, Hari Babu. And the article was included in Synthesis in 2006.Application In Synthesis of Di-tert-butyl decanedioate The following contents are mentioned in the article:

A practical and green chem. process for the esterification of carboxylic acids with alcs. and transesterification of carboxylic esters in good to excellent yields by using K₅CoW₁₂O₁₄·3H₂O (0.1 mol%) as catalyst is reported. The catalyst exhibited remarkable reusable activity. This study involved multiple reactions and reactants, such as Di-tert-butyl decanedioate (cas: 143050-66-2Application In Synthesis of Di-tert-butyl decanedioate).

Di-tert-butyl decanedioate (cas: 143050-66-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application In Synthesis of Di-tert-butyl decanedioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of benorylate was written by Shen, Guang-zhi;Zou, Gui-hua;Cai, Yu-ting;Wu, Yi-yan. And the article was included in Liaoning Huagong in 2009.Related Products of 5003-48-5 The following contents are mentioned in the article:

Two synthetic routes of benorylate were put forward and compared in this paper. At last, the second synthetic route which used aspirin and acetaminophen as raw materials and PEG1000 as phase transfer catalyst in esterification was selected to prepare benorylate, and the yield of benorylate can reach 92%. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Related Products of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Related Products of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Thin-layer chromatographic screening of 500 toxicologically relevant substances by corrected R_f values (R_f^c values) in two systems was written by Schuetz, H.;Pielmeyer, A.;Weiler, G.. And the article was included in Aerztliche Laboratorium in 1990.Application of 5003-48-5 The following contents are mentioned in the article:

R_f^c values of 499 drugs of forensic relevance for TLC screening are tabulated, for either MeOH or an 85:10:5 mixture of EtOAc-MeOH-25% NA₄OH as eluent with either codeine, flurazepam, and papaverine or haloperidol, morphine, and quinine as reference substances. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Application of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics