Tag: 300-400

Aglycone Ebselen and β-D-Xyloside Primed Glycosaminoglycans Co-contribute to Ebselen β-D-Xyloside-Induced Cytotoxicity was written by Tang, Yang;Zhang, Siqi;Chang, Yajing;Fan, Dacheng;De Agostini, Ariane;Zhang, Lijuan;Jiang, Tao. And the article was included in Journal of Medicinal Chemistry in 2018.Application In Synthesis of (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate This article mentions the following:

Most β-D-xylosides with hydrophobic aglycons are nontoxic primers for glycosaminoglycan assembly in animal cells. However, when Ebselen was conjugated to D-xylose, D-glucose, D-galactose, and D-lactose (8A-D), only Ebselen β-D-xyloside (8A) showed significant cytotoxicity in human cancer cells. The following facts indicated that the aglycon Ebselen and β-D-xyloside primed glycosaminoglycans co-contributed to the observed cytotoxicity: 1. Ebselen induced S phase cell cycle arrest, whereas 8A induced G2/M cell cycle arrest; 2. 8A augmented early and late phase cancer cell apoptosis significantly compared to that of Ebselen and 8B-D; 3. Both 8A and phenyl-β-D-xyloside primed glycosaminoglycans with similar disaccharide compositions in CHO-pgsA745 cells; 4. Glycosaminoglycans could be detected inside of cells only when treated with 8A, indicating Ebselen contributed to the unique property of intracellular localization of the primed glycosaminoglycans. Thus, 8A represents a lead compound for the development of novel antitumor strategy by targeting glycosaminoglycans. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4Application In Synthesis of (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application In Synthesis of (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tin(II) chloride assisted synthesis of N-protected γ-amino β-keto esters through semipinacol rearrangement was written by Bandyopadhyay, Anupam;Agrawal, Neha;Mali, Sachitanand M.;Jadhav, Sandip V.;Gopi, Hosahudya N.. And the article was included in Organic & Biomolecular Chemistry in 2010.Related Products of 87694-53-9 This article mentions the following:

A facile synthetic route for the preparation of N-protected γ-amino β-keto esters from amino aldehydes and Et diazoacetate is described. The two component coupling is facilitated by tin(II) chloride followed by semipinacol rearrangement leading to the product in quant. yield. The reaction is mild, instantaneous and compatible with Boc-, Fmoc- and Cbz-amino protecting groups. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Related Products of 87694-53-9).

(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Related Products of 87694-53-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Regio/Stereoselective Glycosylation of Diol and Polyol Acceptors in Efficient Synthesis of Neu5Ac-α-2,3-LacNPhth Trisaccharide was written by Zhang, Ying;Zhao, Fu-Long;Luo, Tao;Pei, Zhichao;Dong, Hai. And the article was included in Chemistry – An Asian Journal in 2019.Name: (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate This article mentions the following:

A concise approach to a Neu5Ac-α-2,3-LacNPhth trisaccharide derivative was developed. First, the regio/stereoselective glycosylation between glycoside donors and glucoNPhth diol acceptors was investigated. It was found that the regioselectivity depends not only on the steric hindrance of the C2-NPhth group and the C6-OH protecting group of the glucosamine acceptors, but also on the leaving group and protecting group of the glycoside donors. Under optimized conditions, LacNPhth derivatives were synthesized in up to 92 % yield through a regio/stereoselective glycosylation between peracetylated-α-galactopyranosyl trichloroacetimidate and p-methoxyphenyl 6-O-tert-butyldiphenylsilyl-2-deoxy-2-phthalimido-β-D-glucopyranoside, avoiding the formation of glycosylated orthoesters and anomeric aglycon transfer. Then, the LacNPhth derivative was deacylated and then protected on the primary position by TBDPS to form a LacNPhth polyol acceptor. Finally, the Neu5Ac-α-2,3-LacNPhth derivative was synthesized in 48 % yield through the regio/stereoselective glycosylation between the LacNPhth polyol acceptor and a sialyl phosphite donor. Starting from D-glucosamine hydrochloride, the target Neu5Ac-α-2,3-LacNPhth derivative was synthesized in a total yield of 18.5 % over only 10 steps. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4Name: (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Free fatty acid from waste palm oil functionalized magnetic nanoparticles immobilized on surface graphene oxide as a new adsorbent for simultaneously detecting hazardous polycyclic aromatic hydrocarbons and phthalate esters in food extracts was written by Mohamad, Sharifah;Bakhshaei, Shabnam;Abdul Manan, Ninie Suhana;Parmin, N. A.;Rozi, Siti Khalijah Mahmad. And the article was included in Journal of Nanoscience and Nanotechnology in 2021.Application In Synthesis of Dicyclohexyl phthalate This article mentions the following:

A newly synthesized free fatty acids from waste palm oil functionalized magnetic nanoparticles immobilized on the surface of graphene oxide (FFA@MNP-GO) was successfully synthesized and characterized in this research. The combinations of long alkyl chain of free fatty acid with graphene oxide that consists of large delocalized π-electron systems and abundant of hydrophilic groups with hydroxyl, epoxide and carboxylic groups offer the determination of simultaneous wide range of polarities of organic pollutants in real matrixes through hydrogen bonding, hydrophobic and π-π interactions. The fabricated adsorbent was successfully applied as a magnetic solid phase extraction (MSPE) adsorbent for the simultaneous separation of selected phthalate esters (PAEs) and polycyclic aromatic hydrocarbons (PAHs) in apple and cabbage extracts prior to their high performance liquid chromatog. with diode-array detector determination Factors affecting the extraction efficiency such as amount of adsorbent, desorption solvent, volume of desorption solvent, extraction time, desorption time, pH and sample volume were investigated and optimized. The results revealed that under optimal conditions, the detection limit of selected PAEs and PAHs were in the range of 0.56-0.97 ng mL^-1 and 0.02-0.93 ng mL^-1, resp. The spiked recoveries of real apple and cabbage extracts for PAEs and PAHs were in the range of 81.5-117.6% with good relative standard deviation (RSD) (n = 5) less than 10% and 86.7-118.2% with acceptable RSDs (n = 5) ranging from 1.5 to 11.0%, resp. This study reported for the first time the use of MSPE procedure for simultaneous determination of chosen PAHs and PAEs in real samples including apple and cabbage extracts by using new adsorbent, FFA@MNP-GO. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Application In Synthesis of Dicyclohexyl phthalate).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of Dicyclohexyl phthalate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthes1is of glycosyl sulfoximines by a highly chemo- and stereoselective NH- and O-transfer to thioglycosides was written by Tota, Arianna;Carlucci, Claudia;Pisano, Luisa;Cutolo, Giuliano;Clarkson, Guy J.;Romanazzi, Giuseppe;Degennaro, Leonardo;Bull, James A.;Rollin, Patrick;Luisi, Renzo. And the article was included in Organic & Biomolecular Chemistry in 2020.Formula: C16H22O11 This article mentions the following:

A synthesis of unprecedented and stable glycosyl sulfoximines is reported. The developed strategies represent the first example of highly stereoselective sulfoximine formation directly from thioglycosides. This synthetic protocol has been tested on several β-thioglycosides bearing different aromatics and alkyls as S-substituents, and bearing glucose, mannose and galactose as glycosyl units. The process has been extended to a lactose derived thioglycoside and to a glucose derived sulfenamide. The process was chemo- and stereoselective, and X-ray anal. confirmed the structure and provided stereochem. information on the configuration at the sulfur atom. A model for the stereochem. outcome is proposed based on the steric environment of the sulfide. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4Formula: C16H22O11).

(2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Formula: C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Biomimetic nanoparticles deliver mRNAs encoding costimulatory receptors and enhance T cell mediated cancer immunotherapy was written by Li, Wenqing;Zhang, Xinfu;Zhang, Chengxiang;Yan, Jingyue;Hou, Xucheng;Du, Shi;Zeng, Chunxi;Zhao, Weiyu;Deng, Binbin;McComb, David W.;Zhang, Yuebao;Kang, Diana D.;Li, Junan;Carson, William E. III;Dong, Yizhou. And the article was included in Nature Communications in 2021.Category: esters-buliding-blocks This article mentions the following:

Abstract: Antibodies targeting costimulatory receptors of T cells have been developed for the activation of T cell immunity in cancer immunotherapy. However, costimulatory mol. expression is often lacking in tumor-infiltrating immune cells, which can impede antibody-mediated immunotherapy. Here, we hypothesize that delivery of costimulatory receptor mRNA to tumor-infiltrating T cells will enhance the antitumor effects of antibodies. We first design a library of biomimetic nanoparticles and find that phospholipid nanoparticles (PL1) effectively deliver costimulatory receptor mRNA (CD137 or OX40) to T cells. Then, we demonstrate that the combination of PL1-OX40 mRNA and anti-OX40 antibody exhibits significantly improved antitumor activity compared to anti-OX40 antibody alone in multiple tumor models. This treatment regimen results in a 60% complete response rate in the A20 tumor model, with these mice being resistant to rechallenge by A20 tumor cells. Addnl., the combination of PL1-OX40 mRNA and anti-OX40 antibody significantly boosts the antitumor immune response to anti-PD-1 + anti-CTLA-4 antibodies in the B16F10 tumor model. This study supports the concept of delivering mRNA encoding costimulatory receptors in combination with the corresponding agonistic antibody as a strategy to enhance cancer immunotherapy. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4Category: esters-buliding-blocks).

(2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pillar[5]arene-Based Polycationic Glyco[2]rotaxanes Designed as Pseudomonas aeruginosa Antibiofilm Agents was written by Mohy El Dine, Tharwat;Jimmidi, Ravikumar;Diaconu, Andrei;Fransolet, Maude;Michiels, Carine;De Winter, Julien;Gillon, Emilie;Imberty, Anne;Coenye, Tom;Vincent, Stephane P.. And the article was included in Journal of Medicinal Chemistry in 2021.Quality Control of (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate This article mentions the following:

Pseudomonas aeruginosa (P.A.) is a human pathogen belonging to the top priorities for the discovery of new therapeutic solutions Its propensity to generate biofilms strongly complicates the treatments required to cure P. A. infections. Herein, we describe the synthesis of a series of novel rotaxanes composed of a central galactosylated pillar[5]arene, a tetrafucosylated dendron, and a tetraguanidinium subunit. Besides the high affinity of the final glycorotaxanes for the two P. A. lectins LecA and LecB, potent inhibition levels of biofilm growth were evidenced, showing that their three subunits work synergistically. An antibiofilm assay using a double LecA and LecB mutant compared to the wild type demonstrated that the antibiofilm activity of the best glycorotaxane is lectin-mediated. Such antibiofilm potency had rarely been reached in the literature. Importantly, none of the final rotaxanes was bactericidal, showing that their antibiofilm activity does not depend on bacteria killing, which is a rare feature for antibiofilm agents. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4Quality Control of (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Quality Control of (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Environmental implications from the priority pollutants screening in impoundment reservoir along the eastern route of China′s South-to-North Water Diversion Project was written by Zhao, Zhonghua;Gong, Xionghu;Ding, Qiqi;Jin, Miao;Wang, Zhaode;Lu, Shaoyong;Zhang, Lu. And the article was included in Science of the Total Environment in 2021.SDS of cas: 84-61-7 This article mentions the following:

Screening priority pollutants from vast anthropogenic contaminants discharged into aquatic environment is urgent for protecting water quality definitely. The multi-criteria scoring method involved in the occurrence (O), persistence (P), bioaccumulation (B), ecol. risk (Eco-T), and human health risk (Hum-T), was established for pollutants prioritization in waters and applied in Dongping Lake, the final impoundment reservoir along the eastern route of China′s South-to-North Water Diversion Project (SNWDP). A total of 170 chems. including heavy metals (HMs), volatile organic chems. (VOCs), polycyclic aromatic hydrocarbons (PAHs), organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), phthalate esters (PAEs), and antibiotics (ANTs) were investigated as the candidates. Accordingly, 42 chems. including 8 PAEs, 7 OCPs, 7 PCBs, 5 PAHs, 13 HMs, and 2 VOCs were made up the list of priority pollutants for Dongping Lake, suggesting the necessity of routine monitoring high priority groups and revising the existing list. Multiple risk assessment indicated higher ecol. and human health risks induced by HMs than by organic pollutants. Spatial distribution of risks stressed the retention of toxic organic chems. by the lake body and the accumulation of HMs along the transfer route, resp., thus triggering ecosystem responses and potential effects on the water-receiving areas as expected. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7SDS of cas: 84-61-7).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.SDS of cas: 84-61-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Occurrence and migration of phthalates in adhesive materials to fruits and vegetables was written by Hou, Haonan;Min, Yihao;Liu, Xueke;Wang, Peng;Zhou, Zhiqiang;Liu, Donghui. And the article was included in Journal of Hazardous Materials in 2021.Application of 84-61-7 This article mentions the following:

Labels or tapes are widely used on fresh fruits and vegetables, which may contain phthalates (PAEs). There are few studies on the contamination pathway of PAEs from labels or tapes to food stuff. In this study, the concentrations of eleven PAEs in adhesive labels, tapes, labeled fruits and vegetables on the market were investigated. The eleven PAEs were detected with the total concentration of 7.44-30.51 mg/m2 in labels and tapes. Di-Et phthalate (DEP), di-Bu phthalate (DIBP), di-Me phthalate (DMP), Bis (2-ethylhexyl) phthalate (DEHP) and di-Bu phthalate (DBP) had the highest detection frequency in adhesive material samples. The concentrations of PAEs in labeled fruits were higher than that in unlabeled fruits, especially in the peel, indicating PAEs could transfer from labels or tapes to fruits and vegetables. Furthermore, the migration behaviors of PAEs from labels or tapes to apples, avocados and celery were investigated. It was found that the PAEs could penetrate to apple and avocado pulp through the peel, resulting in the residue of the PAEs in the whole fruit. Unlike apple peel, the thick avocado peel was more difficultly penetrated by the PAEs. Due to the high lipid content, the PAEs distributed more evenly in avocado pulp than in apple pulp. The migrations up to a maximum of 4.16 mg/kg were found for Bu benzyl phthalate (BBP) in avocado peel and up to a maximum of 0.188 mg/kg in avocado pulp. The average migration of the PAEs in celery ranged from 0.3 to 26.1 μg/kg in three days and the low migration might result from the rough surface and less contacting area. These findings suggest that the use of labels or tapes in direct contact may increase the risk of PAEs exposure to humans through fruits and vegetables. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Application of 84-61-7).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application of 84-61-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chemical characteristics and toxicological effects of leachates from plastics under simulated seawater and fish digest was written by Qiu, Shu-Qing;Huang, Guo-Yong;Fang, Gui-Zhen;Li, Xiao-Pei;Lei, Dong-Qiao;Shi, Wen-Jun;Xie, Lingtian;Ying, Guang-Guo. And the article was included in Water Research in 2022.COA of Formula: C20H26O4 This article mentions the following:

In recent years, the ecol. risks of plastics to marine environments and organisms have attracted increasing attention, especially the leachates from plastics. However, a comprehensive knowledge about the leaching characteristics and subsequent toxicol. effects of leachates is still sparse. In this study, 15 different plastic products were immersed in simulated seawater and fish digest for 16 h. The leachates were analyzed through non-target and target analyses and their toxicol. signatures were assessed by bioassays. In total, 240 additives were identified from the plastic leachates, among which plasticizers represented the most (16.7%), followed by antioxidants (8.7%) and flame retardants (7.1%). Approx. 40% of plastic leachates exhibited significant inhibitory effects on the bioluminescence using a recombinant luminescent assay. In addition, both the hyperactive and hypoactive behaviors were displayed in the larvae of marine medaka (Oryzias melastigma) exposed to some plastic leachates. In general, the number and amount of identified compounds under simulated fish digest were less than those under simulated seawater. However, the simulated fish digest leachates triggered higher toxicity. Redundancy anal. demonstrated that identified additives did not adequately explain the toxicol. effects. Future research should focus on the identification of more additives in the plastic leachates and their potential ecol. risks. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7COA of Formula: C20H26O4).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C20H26O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics