Tag: 200-300

Comparison of volatile compounds released by entomopathogenic fungi was written by Bojke, Aleksandra;Tkaczuk, Cezary;Stepnowski, Piotr;Golebiowski, Marek. And the article was included in Microbiological Research in 2018.Formula: C15H22O2 The following contents are mentioned in the article:

Entomopathogenic fungi are fungal species which are used as a potential source of biopesticides. These fungi produce secondary metabolites which in insects can cause disruption in the normal functioning of their bodies, disease or even death. In order to fully characterize the physiol. of entomopathogenic fungi we should identify the volatile organic compounds which are involved in this process. Therefore, we conducted a qual. and quant. anal. of volatile compounds produced by entomopathogenic fungi. Seven different species of fungi were analyzed: Metarhizium anisopliae, Metarhizium flavoviride, Pandora sp., Isaria fumosorosea, Hirsutella danubiensis, Batkoa sp. and Beauveria bassiana. The analyses were performed using the HS-SPME/GC-MS technique. In the analyzed fungi, 63 volatile compounds were identified and classified into the following groups: aldehydes, ketones, alcs., esters, acids, terpenes and others. The results show that entomopathogenic fungi produce a wide profile of secondary metabolites. Principal Components Anal. was used to determine whether sep. classes of fungi can be distinguished from one another based on their metabolite profiles. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Formula: C15H22O2).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Formula: C15H22O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Regional convergence in the reaction of heterosubstituted allylic carbanions via allylic aluminum and boron ate complexes was written by Yamamoto, Yoshinori;Yatagai, Hidetaka;Saito, Yoshikazu. And the article was included in Journal of Organic Chemistry in 1984.Electric Literature of C14H24O2 The following contents are mentioned in the article:

The regiochem. in reactions of heterosubstituted allylic carbanions (I) is highly controlled via allylic Al or B ate complexes which direct both carbonyl compounds and reactive halides to the α-position with high regioselectivity. For example, carbonyl compounds react with I [R = Me₂CHO (II), MeOCH₂O (III), Me₂CHS (IV), PhSe, Me₃Si] at the α-position via the ate complexes. Although the reactions of the ate complexes (V) with aldehydes generally produce a mixture of erythro and threo isomers, the Al ate complex of III gives the erythro isomer with very high stereoselectivity. This procedure is applied to the stereoselective synthesis of exo-brevicomin. With allylic halides, the II and IV substituted allylic carbanions again react at the α-position via the ate complexes. However, the coupling mode is entirely different; the α-α’ coupling product is obtained from II, while the α-γ’ coupling product is produced from IV. This study involved multiple reactions and reactants, such as (E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7Electric Literature of C14H24O2).

(E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Electric Literature of C14H24O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hydrolytic degradation of isosorbide-based polycarbonates: Effects of terminal groups, additives, and residue catalysts was written by Yan, Shengdi;Wu, Guozhang. And the article was included in Polymer Degradation and Stability in 2021.SDS of cas: 102-09-0 The following contents are mentioned in the article:

The hydrolysis degradation of bisphenol-A polycarbonate (BPA-PC), isosorbide (ISB)-co-1,4-cyclohexanedimethanol (CHDM) polycarbonate (IcC-PC), and BPA-PC/IcC-PC reactive blends were systematically investigated. The terminal hydroxyl groups of BPA-PC, thermally derived chem. structure on IcC-PC chains, and derivatives from phosphite antioxidants trigger severe hydrolysis degradation 1H-NMR anal. shows that carbonate groups connected to the BPA unit are most susceptible to hydrolysis, followed by ISB and CHDM units, demonstrating that the acidity of monomers plays a key role in the hydrolysis degradation of polycarbonates. Residual catalysts may cause significant hydrolysis in BPA-PC/IcC-PC reactive blends. Hydrolysis prefers to occur on the exo position of ISB unit with a low steric hindrance rather than on the endo position with a high electrophilicity, indicating that the residual catalyst acts as a Lewis acid and likely promotes hydrolysis through coordination mechanism. The hydrolysis resistance of BPA-PC/IcC-PC blends with a Na-based catalyst is lower than that of blends with K- and Cs-based catalysts because of the strong coordination ability. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0SDS of cas: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.SDS of cas: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Amphiphilic methoxy poly(ethylene glycol)-b-poly(carbonate-selenide) with enhanced ROS responsiveness: Facile synthesis and oxidation process was written by Li, Siqi;Song, Fangqin;Sun, Chuanhao;Hu, Jieni;Zhang, Yan. And the article was included in European Polymer Journal in 2021.Electric Literature of C13H10O3 The following contents are mentioned in the article:

The synthesis of ROS-responsive polymers has attracted much attentions in recent years. Herein, we report a series of amphiphilic methoxy poly(ethylene glycol)-b-poly(carbonate-selenide)s (mPEG₄₅-b-poly(MSe)_m, m = 12, 24, 36, 48, 60) by introducing selenide groups onto the backbone via one-pot lipase-catalyzed ring-opening polymerization (ROP), the synthesized amphiphilic polymers with enhanced ROS-responsiveness can self-assemble to form nanoparticles. NMR, Gel Permeation Chromatog. and Fourier Transform IR are employed to confirm the structure of the polymers. Besides, the oxidation process of mPEG₄₅-b-poly(MSe)_m nanoparticles is also clarified. UV-visible Spectrophotometer, Dynamic Light Scattering and Transmission Electron Microscopy are further utilized to demonstrate the turbidity, morphol. and size changes under oxidization, proving that the selenide groups endow the mPEG₄₅-b-poly(MSe)_m nanoparticles with enhanced ROS-response properties. Therefore, the above studies highlight the synthesized ROS-responsive polymers and provided a potential material for further applications. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Electric Literature of C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The influence of the surface properties of silicon-fluorine hydrogel on protein adsorption was written by Xie, Haijiao;Zhao, Zhengbai;An, Shuangshuang;Jiang, Yong. And the article was included in Colloids and Surfaces, B: Biointerfaces in 2015.Name: 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate The following contents are mentioned in the article:

A range of fluorinated hydrogels were synthesized using the copolymerization of 1, 1, 1, 3, 3, 3-hexafluoroisopropyl methacrylate (HFMA) or 1H, 1H, 7H-dodecafluoroheptyl methacrylate (DFMA) with hydrophilic monomers. Bovine serum albumin (BSA) and Lysozyme (LZM) were chosen as model proteins to investigate the performance of protein adsorption on the surface of these fluorinated hydrogels. It was found that the performance of the fluorinated hydrogels toward protein adsorption was different for different proteins; simultaneously, the amount of protein adsorption was related to but not linear with the fluorine content on the hydrogel surface. With increasing HFMA content, the mass of BSA adsorption increased in the first stage and then decreased, meanwhile the mass of LZM adsorption exhibited an upward trend in general. In addition, the amount of protein adsorption was also related to the type and length of the fluorinated groups. The hydrogels made from DFMA behaved better than HFMA hydrogels in terms of reducing protein adsorption. This study might provide further reference in choosing fluorine monomer to prepare protein-repelling hydrogels. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3Name: 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Evaluation of EDTA Dianhydride Versus Diphenyl Carbonate Nanosponges for Curcumin was written by Mashaqbeh, Hadeia;Obaidat, Rana;Al-shar’i, Nizar A.. And the article was included in AAPS PharmSciTech in 2022.SDS of cas: 102-09-0 The following contents are mentioned in the article:

Cyclodextrin-based nanosponges are widely investigated for several applications and are considered potential drug carriers. The method of nanosponges preparation involves the use of chem. crosslinking agents where the properties of Nanosponges can be affected. This study compared the resulting differences in the final nanosponges’ properties using carbonate and dianhydride crosslinkers. Di-Ph carbonate and EDTA dianhydride were used for the synthesis of nanosponges. Both types of nanosponges were loaded with curcumin as a model drug. Physicochem. characterizations, including PXRD, DSC, FTIR, SEM, AFM, particle size, zeta potential, and surface area anal., were carried out for the prepared nanosponges. Curcumin release and drug content were also evaluated. Nanosponges prepared by Di-Ph carbonate crosslinker resulted in an amorphous form compared to crystalline EDTA-nanosponges. This study reported the successful inclusion and complexation of curcumin inside carbonate cross-linked cyclodextrin-based nanosponges and suggested the phys. entrapment of crystalline curcumin in EDTA dianhydride. These findings were further investigated and supported by computational modeling. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0SDS of cas: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.SDS of cas: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Enhancement of atazanavir solubility using β-cyclodextrin based nanosponges was written by Venkatesh, D. N.. And the article was included in Special Publication – Royal Society of Chemistry in 2020.Product Details of 102-09-0 The following contents are mentioned in the article:

Cyclodextrins are capable in forming inclusion complexation with various mols. resulting in increased solubility of drugs. Recently nanosponges have gained considerable attention, owing to their biocompatibility, nanoporous in nature, capable of forming supra mol. inclusion complexes with both hydrophilic and lipophilic drugs. Nanosponges are nanostructured carriers prepared by reacting cyclodextrin with suitable cross linkers such as carbonyl diimidazole, hexamethylene and di-Ph carbonate. In the present study, Atazanavir (ATZ) was selected as it is BCS Il drug having low solubility (0.11 mg/I) with a log P value of 5.6.4. It is used in the treatment of Human Immunodeficiency Virus (HIV) infection with better potency, but low oral bioavailability. Atazanavir-β-cyclodextrin based nanosponges were prepared with varying concentration of 1,1 carbonyl diimidazole (CDI) as cross linker. The prepared nanosponges were characterized for FTIR spectroscopy study, SEM and in vitro dissolution study. A remarkable increase in the solubility and dissolution rate was observed However, in vivo studies are required to establish the potential effect of this formulation is necessary. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Product Details of 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Use of simultaneous distillation-extraction, supercritical fluid extraction and solid-phase microextraction for characterisation of the volatile profile of Dipteryx odorata (Aubl.) Willd. was written by Bajer, Tomas;Surmova, Silvie;Eisner, Ales;Ventura, Karel;Bajerova, Petra. And the article was included in Industrial Crops and Products in 2018.Safety of 2-Ethylhexyl benzoate The following contents are mentioned in the article:

Head-space solid phase microextraction (HS-SPME), simultaneous distillation-extraction (SDE) and supercritical fluid extraction (SFE) were employed to prepare volatile extracts of tonka beans (Dipteryx odorata). A total of 190 compounds were assigned by gas chromatog./mass spectrometry (GC/MS) together in comparison with retention indexes. These included 156 (HS-SPME), 77 (SDE) and 36 (SFE) compounds (alcs., carbonyl compounds, acids, esters, terpenes, terpenoids, lactones, aliphatic and aromatic hydrocarbons, and other non-categorised compounds). Semiquant. evaluation of individual compounds was performed using gas chromatog. coupled with a flame ionisation detector. The main constituent detected in all extracts was coumarin (51-85%, despite the extraction method) belonging to the group of lactones. A comparison was made among the three methods in terms of volatile profiles, categorisation of compounds and representation of individual groups of compounds Extracts prepared by HS-SPME were rich in alcs., carbonyls and acids than other extracts Results can provide essential information for the application of different treatment of tonka beans in flavor industries. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Safety of 2-Ethylhexyl benzoate).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Safety of 2-Ethylhexyl benzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Design, Synthesis, and Biological Evaluation of 2-Formyl Tetrahydronaphthyridine Urea Derivatives as New Selective Covalently Reversible FGFR4 Inhibitors was written by Zhang, Zhen;Li, Jie;Chen, Hao;Huang, Jing;Song, Xiaojuan;Tu, Zheng-Chao;Zhang, Zhang;Peng, Lijie;Zhou, Yang;Ding, Ke. And the article was included in Journal of Medicinal Chemistry in 2022.HPLC of Formula: 102-09-0 The following contents are mentioned in the article:

Aberrant FGF19/FGFR4 signaling is an oncogenic driver force for the development of human hepatocellular carcinoma (HCC). A series of 2-formyl tetrahydronaphthyridine urea derivatives I (R = 2-phenylethynyl, 2-(pyridin-2-yl)ethynyl, 2-(3-methoxyphenyl)ethyl, etc.; R¹ = F, propan-2-yloxidanyl, cyclopentylaminyl, etc.) and II was designed and synthesized as new covalently reversible inhibitors of FGFR4. The representative compound II (R = 2-(pyridin-3-yl)ethynyl) (III) exhibited an IC₅₀ value of 5.4 nM against FGFR4 and demonstrated extraordinary kinome selectivity. Compound III also exhibited good oral pharmacokinetic properties with an AUC_(0-t) value of 38 950.06 h*ng/mL, a T_1/2 value of 3.06 h, and an oral bioavailability of 50.97%, at an oral dose of 25 mg/kg in Sprague-Dawley (SD) rats. Furthermore, compound III induced significant tumor regressions in a xenograft mouse model of Hep3B2.1-7 HCC cancer cells without an obvious sign of toxicity upon 30 mg/kg oral administration. Compound III may serve as a promising lead compound for further anticancer drug development. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0HPLC of Formula: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Antitumor mechanism of the essential oils from two succulent plants in multidrug resistance leukemia cell was written by Poma, Paola;Labbozzetta, Manuela;Mccubrey, James A.;Ramarosandratana, Aro Vonjy;Sajeva, Maurizio;Zito, Pietro;Notarbartolo, Monica. And the article was included in Pharmaceuticals in 2019.Synthetic Route of C15H22O2 The following contents are mentioned in the article:

Drug resistance remains a major challenge in the treatment of cancer. The multiplicity of the drug resistance determinants raises the question about the optimal strategies to deal with them. Essential oils showed to inhibit the growth of different tumor cell types. Essential oils contain several chem. classes of compounds whose heterogeneity of active moieties can help prevent the development of drug resistance. In the present paper, we analyzed, by gas chromatog.-mass spectrometry the chem. composition of the essential oil of the leaves of Kalanchoe beharensis obtained by hydrodistillation and compared the chem. composition of its essential oil with that of Cyphostemma juttae. Our results demonstrated the anticancer and proapoptotic activities of both species against acute myeloid leukemia on an in vitro model and its multidrug resistant variant involving NF-κB pathway. The essential oils of both species produced a significant decrease in many targets of NF-κB both at mRNA and protein levels. The results corroborate the idea that essential oils may be a good alternative to traditional drugs in the treatment of cancer, especially in drug resistant cancer. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Synthetic Route of C15H22O2).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C15H22O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics