Tag: 200-300

Synthesis and Evaluation of Partly Fluorinated Block Copolymers as MRI Imaging Agents was written by Peng, Hui;Blakey, Idriss;Dargaville, Bronwin;Rasoul, Firas;Rose, Stephen;Whittaker, Andrew K.. And the article was included in Biomacromolecules in 2009.HPLC of Formula: 3063-94-3 The following contents are mentioned in the article:

A series of well-defined diblock copolymers of acrylic acid with partially fluorinated acrylate and methacrylate monomers were synthesized using ATRP as potential ¹⁹F MRI imaging agents. The diblock copolymers could undergo spontaneous self-assembly in mixed and aqueous solvents to form stable micelles with a diameter from approx. 20-45 nm, having a fluorine-rich core that provides a strong signal for MRI examinations The observed MRI image intensities were related to the NMR longitudinal and transverse relaxation times, and were found to depend on polymer structure and method of micellization. Two distinct T₂ relaxation times were measured; on comparison of expected MRI image intensities with those observed exptl., methacrylate polymers show systematically lower signal intensity than acrylate polymers. This is related to the presence of a population of nuclear spins having short T₂ relaxation times that cannot be detected under high-resolution NMR and MRI conditions. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3HPLC of Formula: 3063-94-3).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 3063-94-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

One-Pot Successive Turbo Grignard Reactions for the Facile Synthesis of α-Aryl-α-Trifluoromethyl Alcohols was written by Kani, Ryunosuke;Inuzuka, Toshiyasu;Kubota, Yasuhiro;Funabiki, Kazumasa. And the article was included in European Journal of Organic Chemistry in 2020.SDS of cas: 898787-14-9 The following contents are mentioned in the article:

A novel straightforward one-pot methodol. for two successive turbo Grignard reagent (iPrMgCl·LiCl) reactions, was developed for a facile synthesis of α-aryl-α-trifluoromethyl alcs., motifs of value in pharmaceutical chem. The method displayed broad functional group tolerance, including reducible groups. Dual roles of iPrMgCl·LiCl were exploited in the tandem reaction with com. available iodoarenes or iodoheteroarenes and 2,2,2-trifluoroethyl trifluoroacetate. The process encompasses three successive reactions in a one-pot process: the iPrMgCl·LiCl-mediated iodine/magnesium-exchange reaction of iodoarenes or iodoheteroarenes; nucleophilic addition of various generated aryl or heteroarylmagnesium reagents to 2,2,2-trifluoroethyl trifluoroacetate; and the reduction of in-situ generated aryl trifluoromethyl ketones with iPrMgCl·LiCl, to produce the corresponding α-aryl or α-heteroaryl-α-trifluoromethyl alcs. bearing various substituents, including reducible functional groups in good to excellent yields. This study involved multiple reactions and reactants, such as Ethyl 4-(2,2,2-Trifluoroacetyl)benzoate (cas: 898787-14-9SDS of cas: 898787-14-9).

Ethyl 4-(2,2,2-Trifluoroacetyl)benzoate (cas: 898787-14-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.SDS of cas: 898787-14-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Robust optical oxygen sensors based on polymer-bound NIR-emitting platinum(II)-benzoporphyrins was written by Hutter, L. H.;Muller, B. J.;Koren, K.;Borisov, S. M.;Klimant, I.. And the article was included in Journal of Materials Chemistry in 2014.Category: esters-buliding-blocks The following contents are mentioned in the article:

Several advanced optical oxygen sensor materials are presented. They are based on bright NIR-emitting platinum(II)-benzoporphyrins covalently incorporated into a variety of polymeric matrixes. The dye-polymer conjugates are prepared either via Suzuki coupling of the brominated porphyrins to the styrene backbone or via co-polymerization of the monomers with monostyryl porphyrin derivative Importantly, in both strategies a highly stable C-C bond is obtained. The resulted materials benefit from excellent photophys. properties of the benzoporphyrin dyes (high brightness, emission in the NIR part of the spectrum) and high stability of the covalently grafted materials due to complete suppression of dye migration and leaching. This is particularly important for operation of the sensors in harsh conditions e.g. during steam sterilization where the materials based on noncovalently grafted dyes showed significant drift of their calibration. Addnl., the authors present a new synthetic method for preparation of anal. pure benzoporphyrins via simple 1-step template condensation which a promising alternative to the commonly used Lindsey method. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3Category: esters-buliding-blocks).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cyclodextrin nanosponges inclusion compounds associated with gold nanoparticles for potential application in the photothermal release of melphalan and cytoxan was written by Salazar, Sebastian;Yutronic, Nicolas;Kogan, Marcelo J.;Jara, Paul. And the article was included in International Journal of Molecular Sciences in 2021.Safety of Diphenyl carbonate The following contents are mentioned in the article:

This article describes the synthesis and characterization of β -cyclodextrin-based nanosponges (NS) inclusion compounds (IC) with the anti-tumor drugs melphalan (MPH) and cytoxan (CYT), and the addition of gold nanoparticles (AuNPs) onto both systems, for the potential release of the drugs by means of laser irradiation The NS-MPH and NS-CYT inclusion compounds were characterized using SEM (SEM), X-ray powder diffraction (XRPD), energy dispersive spectroscopy (EDS), thermogravimetric anal. (TGA), UV-Vis, and proton NMR (1H-NMR). Thus, the inclusion of MPH and CYT inside the cavities of NSs was confirmed. The association of AuNPs with the ICs was confirmed by SEM, EDS, TEM, and UV-Vis. Drug release studies using NSs synthesized with different molar ratios of β -cyclodextrin and diphenylcarbonate (1:4 and 1:8) demonstrated that the ability of NSs to entrap and release the drug mols. depends on the crosslinking between the cyclodextrin monomers. Finally, irradiation assays using a continuous laser of 532 nm showed that photothermal drug release of both MPH and CYT from the cavities of NSs via plasmonic heating of AuNPs is possible. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Safety of Diphenyl carbonate).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Safety of Diphenyl carbonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of molecular architecture on the performance of ¹⁹F NMR imaging agents was written by Peng, Hui;Thurecht, Kristofer;Hsu, Steven;Blakey, Idriss;Squires, Oliver;Kurniawan, Nyoman;Rose, Stephen;Whittaker, Andrew K.. And the article was included in ACS Symposium Series in 2011.Application In Synthesis of 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate The following contents are mentioned in the article:

Traditional magnetic resonance medical imaging agents based on paramagnetic ions or particles have a number of critical limitations, namely image contrast is often limited at low concentrations and sensitivity of the agents becomes diminished at higher magnetic field strengths. In this chapter we describe the development of a new class of polymeric imaging agent which relies on direct detection of the NMR signal of fluorine nuclei and hence circumvents these potential problems. The imaging performance of the new materials relies on the maintenance of librational motion of the fluorinated segments, necessary for partial averaging of the otherwise strong dipole-dipole interactions and large chem. shift interactions of the ¹⁹F nuclei. The performance of partially-fluorinated block copolymers assembled into particles is described and related to the interactions of the polymer chains with the surrounding solvent medium. A second generation of materials based on a hyperbranched structure was developed based on the learning obtained from the earlier experiments and these demonstrated excellent in vitro and in vivo imaging performance. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3Application In Synthesis of 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

High-pressure nuclear-magnetic-resonance study of carbon-13 relaxation in 2-ethylhexyl benzoate and 2-ethylhexyl cyclohexanecarboxylate was written by Adamy, S. T.;Grandinetti, P. J.;Masuda, Y.;Campbell, D.;Jonas, J.. And the article was included in Journal of Chemical Physics in 1991.Application of 5444-75-7 The following contents are mentioned in the article:

Natural abundance ¹³C spin-lattice relaxation times and ¹³C-^Hnuclear Overhauser enhancement (NOE) times of 2-ethylhexyl benzoate (EHB) and 2-ethylhexyl cyclohexanecarboxylate (EHC) were measured along isotherms of -20, 0, 20, 40, and 80° at pressures of 1-5000 bars using high-pressure, high-resolution NMR techniques. The ability to use pressure as an exptl. variable allowed a study of a wide range of mol. motions from extreme narrowing into the slow motional regime. In addition, the high-resolution capability even at high pressure permits the measurement of ¹³C and NOE for each individual C in the mols. studied. Relaxation in both mols. is successfully analyzed in terms of a model assuming a Cole-Davidson distribution of correlation times. The comparison of parameters used in the model demonstrates the increased flexibility of the EHC ring over the EHB ring and shows how the presence of the flexible ring contributes to the increased over-all mobility of the EHC mol. The anal. of mol. reorientations in terms of activation volumes indicates that EHB motion is highly restricted at low temperature This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Application of 5444-75-7).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 5444-75-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gas-phase kinetics of OH radicals reaction with a series of fluorinated acrylates and methacrylates at atmospheric pressure and 298 K was written by Tovar, Carmen M.;Teruel, Mariano A.. And the article was included in Atmospheric Environment in 2014.HPLC of Formula: 3063-94-3 The following contents are mentioned in the article:

Rate coefficients for the gas phase reactions of OH radicals with 2,2,2-trifluoroethylmethacrylate (k₁) 1,1,1,3,3,3-hexafluoroisopropylacrylate (k₂), 1,1,1,3,3,3-hexafluoroisopropylmethacrylate (k₃), and 2,2,2-trifluoroethylacrylate (k₄) were determinated to be k₁ = (2.54 ± 0.12) × 10^-11, k₂ = (1.41 ± 0.11) × 10^-11, k₃ = (1.65 ± 0.14) × 10^-11 and k₄ = (1.25 ± 0.13) × 10^-11 cm³ mol.^-1 s^-1, resp. Kinetic experiments were performed at room temperature and atm. pressure using the relative-rate technique with GC-FID anal. This study is the first kinetic for these reactions of OH radicals under atm. pressure. Addnl., the rate constants obtained are compared with other halogenated and non halogenated acrylates and methacrylates to develop structure/reactivity relationships in terms of the presence of fluorine and ester groups and the hydrocarbon chain length. The atm. implications of the reactions were assessed by the estimation of the tropospheric lifetimes of the title reactions. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3HPLC of Formula: 3063-94-3).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.HPLC of Formula: 3063-94-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Energy harvesting by vitrimer-based moist-electric generators was written by Feng, Zihao;Zhao, Wei;Yang, Zhengxin;Deng, Yi;Yang, Tong;Ni, Yonghao. And the article was included in Journal of Materials Chemistry A in 2022.Computed Properties of C13H10O3 The following contents are mentioned in the article:

Exploitation and utilization of green energy are urgent for the sustainable development of human civilization. In this study, we report a series of novel moist-elec. generators (MEGs) based on a polyhydroxyurethane (PHU) vitrimer for the first time. In sharp contrast to traditional polymer MEGs, vitrimer moist-elec. generators (VMEGs) can provide high and sustained voltage outputs under high temperature and high moisture conditions without structural collapse and decomposition Furthermore, after doping with Ti₃C₂, the resultant VMEG can simultaneously convert energy from both water and the sun to elec. energy, providing continuous power for electronic devices, such as timers, under a natural environment. It is noteworthy that the preparation of VMEGs can be easily scaled up by using PHU/cellulose paper composites. The resultant paper-based VMEGs exhibit high elec. output, while possessing excellent mech. properties, good self-healing ability, and high flexibility and transparency. This study provides a novel strategy to fabricate advanced MEGs, and at the same time opens a novel application for vitrimer materials. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Computed Properties of C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Characterization of odors of wood by gas chromatography-olfactometry with removal of extractives as attempt to control indoor air quality was written by Liu, Ru;Wang, Chen;Huang, Anmin;Lv, Bin. And the article was included in Molecules in 2018.COA of Formula: C15H22O2 The following contents are mentioned in the article:

Indoor air quality problems are usually revealed by occupants′ complaints. In this study, the odors of two types of hardwood species, namely, Cathy poplar (Populus cathayana Rehd.) and rubberwood (Hevea brasiliensis) were selected and extracted with ethanol-toluene for removal of extractives in an attempt to eliminate the odors. The odorous components of neat and extracted woods were identified by gas chromatog.-mass spectrometry/olfactometry (GC-MS/O). The results showed that about 33 kinds of key volatile compounds (peak area above 0.2%) were detected from the GC-MS, and about 40 kinds of odorants were identified from GC-O. The components were concentrated between 15 and 33 min in GC-O, which was different from the concentration time in GC-MS. Lots of the odors identified from GC-O were unpleasant to humans, and variously described as stinky, burnt, leather, bug, herb, etc. These odors may originate from the thermos-oxidation of wood components. After extraction, the amounts and intensities of some odorants decreased, while some remained. However, the extraction process resulted in a benzene residue and led to increased benzene odor. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7COA of Formula: C15H22O2).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.COA of Formula: C15H22O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

New synthetic reactions utilizing organosilicon and tin compounds was written by Ochiai, Masahito. And the article was included in Yakugaku Kenkyu no Shinpo in 1986.Computed Properties of C14H24O2 The following contents are mentioned in the article:

Synthesis of functionalized olefins utilizing organosilicon and tin compounds are described. The silicon-directed thermal elimination from β-triethylsilyl sulfoxides followed by protodesilylation provides a new method to achieve the regiospecific introduction of a double bond. Thus, thermolysis of PhCH₂CH(CH₂SiMe₃)S(O)Ph, followed by protodesilylation, gave PhCH₂CH:CH₂. The desulfonation of vinyl sulfones via the β-elimination of β-tributylstannylorganosulfur compounds has been developed and the reaction was applied to the stereoselective synthesis of functionalized olefins, including 1,3-dienes, allenes, vinyl sulfides, vinylsilanes, vinylstannanes, and allylsilanes. Oxidative 1,4-fragmentation of γ-tributylstannyl alcs. using iodosylbenzene produces unsaturated carbonyl compounds; the fragmentation, combined with conjugate addition of tributylstannyllithium and reduction or alkylation, offers an efficient procedure for the reductive and alkylative ring opening of cyclic vinyl ketones. Medium size unsaturated lactones are synthesized by employing the fragmentation as a key step. This study involved multiple reactions and reactants, such as (E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7Computed Properties of C14H24O2).

(E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C14H24O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics