Tag: 200-300

Conversion of γ- and δ-Keto Esters into Optically Active Lactams. Transaminases in Cascade Processes was written by Mourelle-Insua, Angela;Zampieri, Luiz Arthur;Lavandera, Ivan;Gotor-Fernandez, Vicente. And the article was included in Advanced Synthesis & Catalysis in 2018.Formula: C12H13FO3 The following contents are mentioned in the article:

A one-pot two-step enzymic strategy has been designed for the production of optically active γ- and δ-lactams in aqueous medium under mild conditions. The approach is based on the biotransamination of Et or Me keto esters bearing different alkyl or aryl substitution patterns at α-position to the ketone functionality. In this manner, the keto esters were transformed into the corresponding amino esters with excellent conversions, which underwent spontaneous cyclisation in the reaction medium without addition of external reagents. Depending on the transaminase selectivity, both lactam enantiomers can be obtained, so initial enzyme screenings were performed using com. available and made in house enzymes. Reaction conditions were optimized focusing on the substrate concentration, temperature and ratio of amine donor vs acceptor. Thus, ten γ- and δ-lactams were obtained in good to high isolated yields (70-90%) and excellent selectivities (94-99%) after one or two days at 30 or 45 °C. This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2Formula: C12H13FO3).

Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Formula: C12H13FO3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Self-crosslinked poly-L-ornithine and poly-L-arginine networks: Synthesis, characterization, pH-responsibility, biocompatibility, and AIE-functionality was written by Yu, Haixiang;Tong, Zongrui;Bai, Tianwen;Mao, Zhengwei;Ni, Xufeng;Ling, Jun. And the article was included in Journal of Applied Polymer Science in 2021.Related Products of 102-09-0 The following contents are mentioned in the article:

A pH-responsive hydrogel consists of polypeptides only is a promising biomaterial with the advantages of good biocompatibility and non-toxicity. This work reports the synthesis of poly-L-ornithine(poc) (polyLOpoc) serving as the precursor for hydrogels of poly-L-ornithine (polyOrn) and poly(L-arginine-r-L-ornithine) (poly(Arg-r-Orn)). Their controllable degree of crosslinking, good mech. properties, good biocompatibility, and pH-responsibility are detailedly investigated. The swelling ratio of polyOrn hydrogel in acidic aqueous solution is 5.7 times higher than that in a basic environment. In the deprotection of phenoxycarbonyl group, polyLOpoc releases amino pendant groups, which attack the remaining poc-protected amino groups to fulfill self-crosslinking without any crosslinking agent. In addition, the pH-responsive behavior of hydrogels is visualized by aggregation-induced emission phenomena with polyOrn and poly(Arg-r-Orn) containing tetrakis(4-aminophenyl)ethene moisture. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Related Products of 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Related Products of 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Prediction of Collision Cross Section Values: Application to Non-Intentionally Added Substance Identification in Food Contact Materials was written by Song, Xue-Chao;Dreolin, Nicola;Damiani, Tito;Canellas, Elena;Nerin, Cristina. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Category: esters-buliding-blocks The following contents are mentioned in the article:

The synthetic chems. in food contact materials can migrate into food and endanger human health. In this study, the traveling wave collision cross section in nitrogen values of more than 400 chems. in food contact materials were exptl. derived by traveling wave ion mobility spectrometry. A support vector machine-based collision cross section (CCS) prediction model was developed based on CCS values of food contact chems. and a series of mol. descriptors. More than 92% of protonated and 81% of sodiated adducts showed a relative deviation below 5%. Median relative errors for protonated and sodiated mols. were 1.50 and 1.82%, resp. The model was then applied to the structural annotation of oligomers migrating from polyamide adhesives. The identification confidence of 11 oligomers was improved by the direct comparison of the exptl. data with the predicted CCS values. Finally, the challenges and opportunities of current machine-learning models on CCS prediction were also discussed. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Category: esters-buliding-blocks).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Changes of Flavor Compounds of Hydrolyzed Chicken Bone Extracts during Maillard Reaction was written by Sun, Hong-Mei;Wang, Jin-Zhi;Zhang, Chun-Hui;Li, Xia;Xu, Xiong;Dong, Xian-Bing;Hu, Li;Li, Chun-Hong. And the article was included in Journal of Food Science in 2014.Application In Synthesis of 2-Ethylhexyl benzoate The following contents are mentioned in the article:

Flavor quality, including non-volatile and volatile compounds, of hydrolyzed chicken bone extracts (HCBE) during Maillard reaction (MR) was evaluated with HPLC, tasting sensory system, Electronic-Nose (E-nose), and GC-MS. Results showed that flavor amino acids (AA) accounted for 72% to 74% of total free AA in HCBE. Taste of umami increased first and then decreased during MR, while equivalent umami concentration remained at a stable level. Results of taste sensing system and bitter AA showed that MR could reduce the bitter taste of HCBE significantly. E-Nose test showed there are great changes of volatile flavor during MR. And total of 59 volatile compounds were identified in HCBE during MR, which should responsible for the increase of flavor in HCBE. Our results indicated that MR could be used as an effective way to change the flavor compounds in HCBE, and therefore provide a strategy for preparation of meaty flavor enhancer from bone residue as a byproduct of meat industry. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Application In Synthesis of 2-Ethylhexyl benzoate).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application In Synthesis of 2-Ethylhexyl benzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Analysis of volatile composition of Chinese oat wine and Chinese quinoa wine by headspace solid phase micro-extraction and gas chromatography-mass spectrometry was written by Liu, Hao;Liu, Xiao-jie;Ren, Gui-xing. And the article was included in Shipin Gongye Keji in 2015.Name: 2-Ethylhexyl benzoate The following contents are mentioned in the article:

The volatile characteristics of Chinese oat wine and Chinese quinoa wine were investigated using headspace solid phase micro-extraction and gas chromatog.-mass spectrometry. A total of 86 volatile components were identified with 26 kinds existing simultaneously in both. And there were 57 and 55 volatile components in Chinese oat wine and Chinese quinoa wine resp. The volatile composition of Chinese quinoa wine was 15 kinds of volatile compounds (64.09%), 7 kinds of alcs. (29.36%), 13 kinds of esters (4.37%) and 22 kinds of other compounds (2.18%) while the Chinese oat wine was composed of 14 kinds of volatile compounds (43.77%), 6 kinds of alcs. (27.39%), 15 kinds of esters (22.66%) and 22 kinds of others (6.18%). The volatile compounds in high content were phenylethyl alc. and 3-methyl-1-butanol. Some compounds such as BHA and BHT were also detected in both two wines and which suggested that Chinese oat wine and Chinese quinoa wine might have strong anti-oxidant activity. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Name: 2-Ethylhexyl benzoate).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Name: 2-Ethylhexyl benzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Phosgene-free and Chemoselective Synthesis of Novel Polyureas from Activated L-Lysine with Diphenyl Carbonate was written by Yakeya, Daisuke;Yoshida, Yoshiaki;Endo, Takeshi. And the article was included in Macromolecules (Washington, DC, United States) in 2020.SDS of cas: 102-09-0 The following contents are mentioned in the article:

N_α,N_ε-(Phenoxycarbonyl)-L-lysine Me ester 1a can be expected to behave as a difunctional blocked diisocyanate monomer derived from L-lysine with di-Ph carbonate. In this report, we examined a reaction of the obtained compound 1a and 1 equiv of n-butylamine as a model reaction to find that the N_α position of compound 1a reacted selectively with an amine. This means that the reactivity of N_α– and N_ε-phenoxycarbonyl groups is different because the N_α-phenoxycarbonyl moiety has an adjacent ester group. From this result, synthesis of the corresponding polyureas was evaluated by a stepwise reaction of compound 1a with various diamines. The structure anal. and the study of thermal properties of the synthesized polyureas suggested that the carbodiimide moieties were partly constructed in the main chain because of the dehydration triggered by heat treatment of the polyureas. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0SDS of cas: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.SDS of cas: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of the Composition of Copolymers Based on Glycidyl Methacrylate and Fluoroalkyl Methacrylates on the Free Energy and Lyophilic Properties of the Modified Surface was written by Klimov, Viktor V.;Kolyaganova, Olga V.;Bryuzgin, Evgeny V.;Navrotsky, Alexander V.;Novakov, Ivan A.. And the article was included in Polymers (Basel, Switzerland) in 2022.SDS of cas: 3063-94-3 The following contents are mentioned in the article:

This study proposes to use reactive copolymers based on glycidyl methacrylate and fluoroalkyl methacrylates with a low fluorine content in the monomer unit as agents to reduce the surface free energy (SFE). This work reveals the effect of the structure and composition of copolymers on the SFE and water-repellent properties of these coatings. On a smooth surface, coatings based on copolymers of glycidyl methacrylate and fluoroalkyl methacrylates with fluorine atoms in the monomer unit ranging from three to seven are characterized by SFE values in the range from 25 to 13 mN/m, which is comparable to the values for polyhedral oligomeric silsesquioxanes and perfluoroalkyl acrylates. On textured aluminum surfaces, the obtained coatings provide time-stable superhydrophobic properties with contact angles up to 170° and sliding angles up to 2°. The possibility of using copolymers based on glycidyl methacrylate and fluoroalkyl methacrylates for the creation of self-cleaning polymer coatings is shown. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3SDS of cas: 3063-94-3).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.SDS of cas: 3063-94-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

ω-Hydroxy isoprenoid bisphosphonates as linkable GGDPS inhibitors was written by Bhuiyan, Nazmul H.;Varney, Michelle L.;Bhattacharya, Deep S.;Payne, William M.;Mohs, Aaron M.;Holstein, Sarah A.;Wiemer, David F.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2019.Computed Properties of C12H18O3 The following contents are mentioned in the article:

The enzyme geranylgeranyl diphosphate synthase (GGDPS) is a potential therapeutic target for multiple myeloma. Malignant plasma cells produce and secrete large amounts of monoclonal protein, and inhibition of GGDPS results in disruption of protein geranylgeranylation which in turn impairs intracellular protein trafficking. Our previous work has demonstrated that some isoprenoid triazole bisphosphonates are potent and selective inhibitors of GGDPS. To explore the possibility of selective delivery of such compounds to plasma cells, new analogs with an ω-hydroxy group have been synthesized and examined for their enzymic and cellular activity. These studies demonstrate that incorporation of the ω-hydroxy group minimally impairs GGDPS inhibitory activity. Furthermore conjugation of one of the novel ω-hydroxy GGDPS inhibitors to hyaluronic acid resulted in enhanced cellular activity. These results will allow future studies to focus on the in vivo biodistribution of HA-conjugated GGDPS inhibitors. This study involved multiple reactions and reactants, such as (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5Computed Properties of C12H18O3).

(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C12H18O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Profiling of volatile and non-phenolic metabolites-Amino acids, organic acids, and sugars of green tea extracts obtained by different extraction techniques was written by Das, Protiva Rani;Kim, Youngmok;Hong, Seong-Jin;Eun, Jong-Bang. And the article was included in Food Chemistry in 2019.Product Details of 5444-75-7 The following contents are mentioned in the article:

Volatile compounds and non-phenolic metabolites (amino acids, organic acids, and sugars) of aqueous green tea extracts obtained by ultrasonic extraction (UE), agitation extraction (AE), hot water extraction (HWE), and conventional extraction (CE) were determined using SPME-GC-MS and HPLC, resp. Significantly higher (P < 0.05) yields of volatiles and non-phenolic metabolites were obtained via UE and AE than via HWE and CE. UE, AE, HWE, and CE released 212, 201, 103, and 65 volatiles, resp. Sum total of amino acid and organic acid in extracts was 54.57, 54.35, 27.11, and 12.67 (mg/100 g), and 5.96, 6.19, 3.81, and 1.68 (mg/100 g) for UE, AE, HWE, and CE, resp. Volatiles except nitrogen-containing compounds had higher pos. correlations with L-theanine, sucrose, malic acid, and catechins yields. Findings of the current study suggest that an efficient extraction technique may significantly increase volatile and non-phenolic metabolite yields in aqueous green tea extract This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Product Details of 5444-75-7).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Product Details of 5444-75-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Multicolor and multistage response electrochromic color-memory wearable smart textile and flexible display was written by Wang, Chengcheng;Jiang, Xiaojun;Cui, Peng;Sheng, Mingfei;Gong, Xiaodan;Zhang, Liping;Fu, Shaohai. And the article was included in ACS Applied Materials & Interfaces in 2021.Recommanded Product: Diphenyl carbonate The following contents are mentioned in the article:

Electrochromic materials have great application in soft displays and devices, but the application of ideal electrochromic textiles still faces challenges owing to the inconvenience of a continuous power supply. Here, electrochromic color-memory microcapsules (ECM-Ms-red, -yellow, and -blue) with a low drive voltage (2.0 V), coloration efficiency (921.6 cm² C^-1), a practical response rate (34.4 s^-1), multistage response discoloration, and good color-memory performance (>72 h) and reversibility (≥1000 cycles) are developed. The color-memory performance is controlled by the energy difference of oxidation-reduction reactions. A multicolor and multistage response electrochromic color-memory wearable smart textile and flexible display are developed that are convenient and energy-efficient for application. The design philosophy of color-memory based on controllable energy difference of reactions has great potential application in sensors and smart textiles. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Recommanded Product: Diphenyl carbonate).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: Diphenyl carbonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics