Tag: 200-300

Farnesyl Diphosphate Analogues with ω-Bioorthogonal Azide and Alkyne Functional Groups for Protein Farnesyl Transferase-Catalyzed Ligation Reactions was written by Labadie, Guillermo R.;Viswanathan, Rajesh;Poulter, C. Dale. And the article was included in Journal of Organic Chemistry in 2007.Safety of (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate The following contents are mentioned in the article:

Eleven farnesyl diphosphate analogs, which contained ω-azide or alkyne substituents suitable for bioorthogonal Staudinger and Huisgen [3+2] cycloaddition coupling reactions, were synthesized. The analogs were evaluated as substrates for the alkylation of peptide cosubstrates by yeast protein farnesyl transferase. Five of the diphosphates were good alternative substrates for farnesyl diphosphate (FPP). Steady-state kinetic constants were measured for the active compounds, and the products were characterized by HPLC and LC-MS. Two of the analogs gave steady-state kinetic parameters (k_cat and K_m) very similar to those of the natural substrate. This study involved multiple reactions and reactants, such as (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5Safety of (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate).

(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Efficient Access to Multifunctional Trifluoromethyl Alcohols through Base-Free Catalytic Asymmetric C-C Bond Formation with Terminal Ynamides was written by Cook, Andrea M.;Wolf, Christian. And the article was included in Angewandte Chemie, International Edition in 2016.Computed Properties of C11H9F3O3 The following contents are mentioned in the article:

The asym. addition of terminal ynamides to trifluoromethyl ketones with a readily available chiral zinc catalyst gives CF₃-substituted tertiary propargylic alcs. in up to 99 % yield and 96 % ee. The exclusion of organozinc additives and base as well as the general synthetic utility of the products are key features of this reaction. The value of the β-hydroxy-β-trifluoromethyl ynamides is exemplified by selective transformations to chiral Z- and E-enamides, an amide, and N,O-ketene acetals. The highly regioselective hydration, stereoselective reduction, and hydroacyloxylation reactions proceed with high yields and without erosion of the ee value of the parent β-hydroxy ynamides. This study involved multiple reactions and reactants, such as Ethyl 4-(2,2,2-Trifluoroacetyl)benzoate (cas: 898787-14-9Computed Properties of C11H9F3O3).

Ethyl 4-(2,2,2-Trifluoroacetyl)benzoate (cas: 898787-14-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Computed Properties of C11H9F3O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Manganese-Catalyzed Hydroborations with Broad Scope was written by Ghosh, Pradip;Jacobi von Wangelin, Axel. And the article was included in Angewandte Chemie, International Edition in 2021.Application of 102-09-0 The following contents are mentioned in the article:

Reductive transformations of easily available oxidized matter are at the heart of synthetic manipulation and chem. valorization. The applications of catalytic hydrofunctionalization benefit from the use of liquid reducing agents and operationally facile setups. Metal-catalyzed hydroborations provide a highly prolific platform for reductive valorizations of stable C:X electrophiles. Here, the authors report an especially facile, broad-scope reduction of various functions including carbonyls, carboxylates, pyridines, carbodiimides, and carbonates under very mild conditions with the inexpensive pre-catalyst Mn(hmds)₂. The reaction could be successfully applied to depolymerizations This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Application of 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application of 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Field trapping of three Epinotia species with (Z,Z)-7,9-dodecadienyl acetate (Lepidoptera: Tortricidae) was written by Reed, D. W.;Chisholm, M. D.. And the article was included in Journal of Chemical Ecology in 1985.Safety of (E)-Dodeca-9,11-dien-1-yl acetate The following contents are mentioned in the article:

A field survey of the geometrical isomers of 7,9-dodecadienyl alc., acetate, and aldehyde has resulted in attractants and inhibitors for 3 species of tortricid moths. Epinotia silvertoniensis And an undescribed Epinotia species were all attracted to (Z,Z)-7,9-dodecadienyl acetate. Another Epinotia species was attracted to (Z,Z)-7,9-dodecadienyl acetate and (Z,Z)-7,9-dodecadien-1-ol. Electroantennogram data and inhibition patterns for one of the Epinotia species were also reported. In addition, E. criddleana was attracted to lures containing (E)-9-dodecenyl acetate. This study involved multiple reactions and reactants, such as (E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7Safety of (E)-Dodeca-9,11-dien-1-yl acetate).

(E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Safety of (E)-Dodeca-9,11-dien-1-yl acetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Analysis of volatile compounds in edible vegetable oils using headspace solid phase micro-extraction and GC-MS was written by Chen, Qiao-qiao;Zhang, Sheng-wan;Li, Mei-ping;Wang, Zhi-juan;Wang, Hong-yan;Li, Lu;Li, Huan. And the article was included in Shipin Kexue (Beijing, China) in 2014.Electric Literature of C15H22O2 The following contents are mentioned in the article:

The volatile compounds in seven kinds of edible vegetable oil including rapeseed oil, flaxseed oil, sesame oil, peanut oil, corn oil, sunflower seed oil, and soybean oil, were extracted and concentrated by headspace solid phase microextraction (HS-SPME), and then separated and identified by gas chromatog.-mass spectrometry (GC-MS). Totally 118 compounds were identified, including acids, aldehydes, alcs., ketones, hydrocarbons, ethers, degradation products of glucosinolates, pyrazines, furans, aromatic compounds, phenols, pyrroles, pyridines, pyrans, thiazoles, esters and other compounds Differences in major volatile compounds from these edible vegetable oils were analyzed and evaluated. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Electric Literature of C15H22O2).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Electric Literature of C15H22O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Useful Catalytic Enantioselective Cationic Double Annulation Reactions Initiated at an Internal π-Bond: Method and Applications was written by Surendra, Karavadhi;Rajendar, Goreti;Corey, E. J.. And the article was included in Journal of the American Chemical Society in 2014.Product Details of 37905-02-5 The following contents are mentioned in the article:

The 1:1 complex of o,o’-dichloro-R-BINOL and SbCl₅ initiates the enantioselective cationic polycyclization of polyunsaturated substrates at a predictable π-bond which may be either terminal or, as shown herein, internal (e.g., I â†?II). The extension of this powerful construction to internal π-bonds expands the scope of this method and opens up very short pathways to numerous chiral polycyclic mols., including natural products and their analogs. Especially simple synthetic routes are disclosed that provide access to dysideapalaunic acid, dehydroabietic acid, and epi-podocarpic acid and illustrate the value of this enantioselective approach. This study involved multiple reactions and reactants, such as (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5Product Details of 37905-02-5).

(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Product Details of 37905-02-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A highly stereoselective synthesis of (E)-1-substituted-1,3-dienes was written by Bloch, R.;Abecassis, J.. And the article was included in Tetrahedron Letters in 1982.Product Details of 50767-78-7 The following contents are mentioned in the article:

Alkylation of sulfone I (R = H) with RCH₂I [R = H, Bu, (CH₂)₇OR¹ (R¹ = tetrahydropyranyl)] gave I [R = Me, (CH₂)₄Me, (CH₂)₈OR¹] (II). Thermolysis of II in the vapor phase at 600-650° gave the corresponding (E)-RCH:CHCH:CH₂ (III) stereospecifically and in 85, 90, and 80-85% yield, resp., by retro-Diels-Alder reaction and in situ SO₂ extrusion. III [R = (CH₂)₈OAc] is a component of the sex pheromone of the red bollworm moth. This study involved multiple reactions and reactants, such as (E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7Product Details of 50767-78-7).

(E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Product Details of 50767-78-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Efficient syntheses of insect sex pheromones emitted by the boll weevil and the red bollworm moth was written by Wollenberg, Robert H.;Peries, Rohan. And the article was included in Tetrahedron Letters in 1979.Quality Control of (E)-Dodeca-9,11-dien-1-yl acetate The following contents are mentioned in the article:

Dimedone on sequential hydrazidation, treatment with aqueous K₂CO₃, hydrogenation, reaction with Z-LiCH:CHOEt (I), and rearrangement gave 44% of a 1:1 mixture of male boll weevil pheromones E– and Z-cyclohexylidene monoterpenoids II. CH₂:CHCH:CH(CH₂)₈OAc, a potent sex pheromone of the virgin female red bollworm moth, was prepared (36%) from CH₂:CH(CH₂)₈OH by sequential tetrahydropyranylation, OsO₄/NaIO₄ oxidation, reaction with I, rearrangement, Wittig methylenation, deprotection, and acetylation. This study involved multiple reactions and reactants, such as (E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7Quality Control of (E)-Dodeca-9,11-dien-1-yl acetate).

(E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Quality Control of (E)-Dodeca-9,11-dien-1-yl acetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Successful reduction of off-target hERG toxicity by structural modification of a T-type calcium channel blocker was written by Choi, Yeon Jae;Seo, Jae Hong;Shin, Kye Jung. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2014.Application of 1061284-70-5 The following contents are mentioned in the article:

To obtain an optimized T-type calcium channel blocker with reduced off-target hERG toxicity, we modified the structure of the original compound by introducing a zwitterion and reducing the basicity of the nitrogen. Among the structurally modified compounds we designed, compounds 5 and 6, which incorporate amides in place of the original compound’s amines, most appreciably alleviated hERG toxicity while maintaining T-type calcium channel blocking activity. Notably, the benzimidazole amide 5 selectively blocked T-type calcium channels without inhibiting hERG (hERG/T-type â‰?220) and L-type channels (L-type/T-type = 96), and exhibited an excellent pharmacokinetic profile in rats. This study involved multiple reactions and reactants, such as Methyl 2-(4-bromophenyl)-3-methylbutanoate (cas: 1061284-70-5Application of 1061284-70-5).

Methyl 2-(4-bromophenyl)-3-methylbutanoate (cas: 1061284-70-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 1061284-70-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Regio- and enantioselective functionalization of acyclic polyprenoids was written by Barrero, Alejandro F.;Quilez del Moral, Jose F.;Herrador, Maria del Mar;Sanchez, Elena M.;Arteaga, Jesus F.. And the article was included in Journal of the Mexican Chemical Society in 2006.Recommanded Product: (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate The following contents are mentioned in the article:

Results obtained in the positional selective functionalization of the double bond located at the terminal isopropylidene unit of acyclic polyprenoids were presented. Studies were undertaken to introduce hydroxyl or related oxygenated functions using oxidation with SeO₂ or catalytic procedures employing Pd(II) catalysts. This functionalization is found in many natural or synthetic acyclic terpenes and would permit subsequent regio- and stereoselective epoxidation reactions. Furthermore, the asym. dihydroxylation procedure was optimized using various polyprenoids in order to generalize this methodol. as the key step for the enantioselective synthesis of epoxides. This study involved multiple reactions and reactants, such as (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5Recommanded Product: (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate).

(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics