Tag: 200-300

Dihydroretinoic acids and their derivatives. Synthesis and biological activity was written by Pawson, Beverly A.;Cheung, H. C.;Han, Ru-Jen L.;Trown, Patrick W.;Buck, Margaret;Hansen, Roseanne;Bollag, W.;Ineichen, U.;Pleil, H.. And the article was included in Journal of Medicinal Chemistry in 1977.Formula: C12H18O3 The following contents are mentioned in the article:

The preparation of the saturated ring analog [19907-33-6] and 12 side-chain dihydro derivatives of retinoic acid are described as well as the activities of the compounds in a chem.-induced mouse skin papilloma test and 2 in vitro vitamin A deficient assays. Dihydro derivatives I [51077-50-0], II [57399-31-2], and III [62924-38-3] retained activity in the papilloma test, but were less potent than the side-chain tetraene parents. I retained significantly more activity than the other dihydro derivatives in the in vitro assays. Structure-activity relations are discussed. This study involved multiple reactions and reactants, such as (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5Formula: C12H18O3).

(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Formula: C12H18O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Periplocain A, a New Naphthalene Derivative from Periploca aphylla Growing in Saudi Arabia was written by Al Musayeib, Nawal M.;Al-Massarani, Shaza M.;Amina, Musarat;El Dib, Rabab A.;Mohamed, Gamal A.;Ibrahim, Sabrin R. M.. And the article was included in Helvetica Chimica Acta in 2016.Recommanded Product: 5444-75-7 The following contents are mentioned in the article:

Periplocain A (I), a new naphthalene derivative together with four known compounds: 2-ethylhexyl benzoate, quercetin-3-O-α-L-rhamnopyranoside, quercetin-3-O-β-D-glucopyranoside and quercetin-3-(6-O-α-L-rhamnopyranosyl-β-D-glucopyranoside) were isolated from the AcOEt fraction of the aerial parts of Periploca aphylla (Asclepiadaceae). Their structures were established by multiple spectroscopic methods in addition to HR-ESI-MS and by comparison with literature data. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Recommanded Product: 5444-75-7).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 5444-75-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

New isoxazole derivatives of retinoids: synthesis and activity on growth and differentiation of tumor cells was written by Simoni, Daniele;Manfredini, Stefano;Tabrizi, Mojgan Aghazadeh;Bazzanini, Rita;Baraldi, Pier G.;Ferroni, Roberto;Traniello, Francesca;Nastruzzi, Claudio;Feriotto, Giordana;Gambari, Roberto. And the article was included in Drug Design and Discovery in 1992.Electric Literature of C12H18O3 The following contents are mentioned in the article:

The effects of several newly synthesized isoxazole analogs of retinoids on differentiation and proliferation of in vitro culture tumor cell lines are reported. Some of the tested compounds exhibit significant differentiating action, inducing adipogenic conversion of the Chinese hamster FH06T1-1 cell line in a range of 2-10 times the activity of retinoic acid and retinol. In addition, most of the compound tested display antiproliferative activity comparable to that of natural retinoids. The reported data could be of interest for exptl. anticancer therapy. This study involved multiple reactions and reactants, such as (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5Electric Literature of C12H18O3).

(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Electric Literature of C12H18O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Organocatalytic Decarboxylative Cyanomethylation of Difluoromethyl and Trifluoromethyl Ketones was written by Balaraman, Kaluvu;Moskowitz, Max;Wolf, Christian. And the article was included in Advanced Synthesis & Catalysis in 2018.Name: Ethyl 4-(2,2,2-Trifluoroacetyl)benzoate The following contents are mentioned in the article:

An efficient organocatalytic method for the synthesis of difluoromethyl and trifluoromethyl substituted β-hydroxynitriles RC(OH)(CXF₂)CH₂CN (R = Ph, cyclohexyl, furan-2-yl, etc.; X = H, F) is introduced. The decarboxylative cyanomethylation of fluorinated ketones RC(O)CXF₂ with readily available cyanoacetic acid gives a variety of tertiary alcs. in high yields and without concomitant water elimination. The reaction occurs in the presence of catalytic amounts of triethylamine, and can be upscaled and applied to chlorofluoromethyl ketones and difluoromethyl ketimines. This study involved multiple reactions and reactants, such as Ethyl 4-(2,2,2-Trifluoroacetyl)benzoate (cas: 898787-14-9Name: Ethyl 4-(2,2,2-Trifluoroacetyl)benzoate).

Ethyl 4-(2,2,2-Trifluoroacetyl)benzoate (cas: 898787-14-9) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Name: Ethyl 4-(2,2,2-Trifluoroacetyl)benzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of racemic 5,9-dimethylheptadecane, the sex pheromone of Leucoptera scitella (Zeller) (Lepidoptera: Lyonetidae) was written by Kovalev, B. G.;Sorochinskaya, A. M.. And the article was included in Khimiya Prirodnykh Soedinenii in 1991.SDS of cas: 37905-02-5 The following contents are mentioned in the article:

Geranyl acetate was oxidized by Me₃COOH and SeO₂ to a diol monoacetate, which was oxidized by pyridinium chlorochromate to the acetoxy aldehyde (I). Wittig reaction of I with [Ph₃PPr]Br gave EtCH:CHCMe:CHCH₂CH₂CMe:CHCH₂OAc, which underwent a Grignard reaction with Me(CH₂)₅MgBr and CuI to give EtCH:CHCMe:CHCH₂CH₂CMe:CH(CH₂)₆Me₃ (II). Hydrogenation of II over Pt/C gave 5,9-dimethylheptadecane. This study involved multiple reactions and reactants, such as (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5SDS of cas: 37905-02-5).

(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.SDS of cas: 37905-02-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Characteristic chemical components of the essential oil from white kwao krua (Pueraria mirifica) was written by Yagi, Nobuo;Nakahashi, Hiroshi;Kobayashi, Tomohiro;Miyazawa, Mitsuo. And the article was included in Journal of Oleo Science in 2013.Category: esters-buliding-blocks The following contents are mentioned in the article:

The components of the essential oil from the roots of Pueraria mirifica were analyzed by capillary gas chromatog.-mass spectrometry (GC-MS). Eighty-two components, representing 88.5% of the total oil, were identified by GC-MS. The main component of the oil was 2-pentylfuran, followed by hexanal and hexadecanol. With regard to the odor components from the essential oil of P. mirifica as determined by gas chromatog.-olfactometry and aroma extract dilution anal., it was revealed that phenylacetaldehyde and (2E)-nonenal imparted the green odor of the oil, and geraniol contributed to the sweet odor. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Category: esters-buliding-blocks).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Photo-on-demand Phosgenation Reactions with Chloroform Triggered by Cl₂ upon Irradiation with Visible Light: Syntheses of Chloroformates, Carbonate Esters, and Isocyanates was written by Suzuki, Yuto;Liang, Fengying;Okazoe, Takashi;Okamoto, Hidekazu;Takeuchi, Yu;Tsuda, Akihiko. And the article was included in Chemistry Letters in 2022.COA of Formula: C13H10O3 The following contents are mentioned in the article:

Chloroform (CHCl₃) upon bubbling with O₂ containing ∼2% Cl₂ underwent oxidative photochem. conversion to phosgene (COCl₂) when exposed to a white LED light. Cl₂ may serve as a visible light-responsive radical initiator in the radical chain reactions of CHCl₃ and O₂. This photochem. reaction allowed both in situ and stepwise one-pot phosgenation reactions, which are simple and safe methods, without expensive apparatus It can be applied to a variety of conventional organic syntheses using phosgene and phosgene oligomers. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0COA of Formula: C13H10O3).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. COA of Formula: C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Variable pressure infrared studies on the molecular dynamics and interactions of the model lubricant, 2-ethylhexyl benzoate (EHB) was written by Whitley, A.;Yarwood, J.;Gardiner, D. J.. And the article was included in Journal of Molecular Structure in 1991.Quality Control of 2-Ethylhexyl benzoate The following contents are mentioned in the article:

The IR spectra of 2-ethylhexyl benzoate (as a model lubricant) was studied at pressures between ambient and 30 kilobars at 293 K in a diamond anvil cell. The ν(C=O) vibrational band profile reflected the effects of both attractive and repulsive potentials through changes in the 1st moment (frequency shift) and dephasing rate (bandwidth). At relatively low pressures (0-5 kilobars), ordering of the mol. dipoles was accompanied by an increase in the distribution of mols. in different micro environments. This may be associated with a multiplicity of interactions at different sites of the mol. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Quality Control of 2-Ethylhexyl benzoate).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Quality Control of 2-Ethylhexyl benzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cooperative copper-squaramide catalysis for the enantioselective N-H insertion reaction with sulfoxonium ylides was written by Furniel, Lucas G.;Echemendia, Radell;Burtoloso, Antonio C. B.. And the article was included in Chemical Science in 2021.Related Products of 102-09-0 The following contents are mentioned in the article:

The first examples of a highly efficient and enantioselective carbene-mediated insertion reaction, from a sulfur ylide, were described. By way of a catalytic asym. insertion reaction into N-H bonds from carbonyl sulfoxonium ylides and anilines, using a copper-bifunctional squaramide cooperative catalysis approach, thirty-seven α-arylglycine esters were synthesized in enantiomeric ratios up to 92:8 (99:1 after a single recrystallization) and reaction yields ranging between 49-96%. Furthermore, the protocol benefited from quick reaction times and was conducted in a straightforward manner. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Related Products of 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Identification of novel GPR81 agonist lead series for target biology evaluation was written by Davidsson, Oejvind;Nilsson, Kristina;Braanalt, Jonas;Andersson, Terese;Berggren, Kristina;Chen, Yantao;Fjellstroem, Ola;Graden, Henrik;Gustafsson, Linda;Hermansson, Nils-Olov;Jansen, Frank;Johannesson, Petra;Ohlsson, Bengt;Tyrchan, Christian;Wellner, Annika;Wellner, Eric;Oelwegaard-Halvarsson, Maria. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2020.Recommanded Product: 102-09-0 The following contents are mentioned in the article:

GPR81 is a novel drug target that is implicated in the control of glucose and lipid metabolism The lack of potent GPR81 modulators suitable for in vivo studies has limited the pharmacol. characterization of this lactate sensing receptor. We performed a high throughput screen (HTS) and identified a GPR81 agonist chem. series containing a central acyl urea scaffold linker. During SAR exploration two addnl. new series were evolved, one containing cyclic acyl urea bioisosteres and another a central amide bond. These three series provide different selectivity and physicochem. properties suitable for in-vivo studies. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Recommanded Product: 102-09-0).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 102-09-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics