Tag: 200-300

Asymmetric Iodolactonization Utilizing Chiral Squaramides was written by Tungen, Joern E.;Nolsoee, Jens M. J.;Hansen, Trond V.. And the article was included in Organic Letters in 2012.Synthetic Route of C12H13FO3 The following contents are mentioned in the article:

Asym. iodolactonization of γ- and δ-unsaturated carboxylic acids has been explored in the presence of six different chiral organocatalysts 5-8. The catalyst I was found to facilitate the cyclization of 5-arylhex-5-enoic acids to the corresponding iodolactones with up to 96% ee. By this protocol, unsaturated carboxylic acids are converted enantioselectively to synthetically useful δ-lactones in high yields using com. available NIS. Apparently, both hydrogen bonding and aryl/aryl interactions are important for efficient stereodifferentiation. This study involved multiple reactions and reactants, such as Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2Synthetic Route of C12H13FO3).

Methyl 5-(4-fluorophenyl)-5-oxopentanoate (cas: 149437-67-2) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Synthetic Route of C12H13FO3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Enantioselective palladaelectro-catalyzed C-H olefinations and allylations for N-C axial chirality was written by Dhawa, Uttam;Wdowik, Tomasz;Hou, Xiaoyan;Yuan, Binbin;Oliveira, Joao C. A.;Ackermann, Lutz. And the article was included in Chemical Science in 2021.Reference of 3063-94-3 The following contents are mentioned in the article:

Enantioselective palladaelectro-catalyzed C-H alkenylations and allylations were achieved with easily-accessible amino acids as transient directing groups. This strategy provided access to highly enantiomerically-enriched N-C axially chiral scaffolds under exceedingly mild conditions. The synthetic utility of the above strategy was demonstrated by a variety of alkenes, while the versatility of the approach was reflected by atroposelective C-H allylations. Computational studies provided insights into a facile C-H activation by a seven-membered palladacycle. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3Reference of 3063-94-3).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 3063-94-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Regioreversed reactions of the trimethylsilyl or phenylselenyl allylic carbanion with carbonyl compounds via allylic aluminum “ate” complexes was written by Yamamoto, Yoshinori;Saito, Yoshikazu;Maruyama, Kazuhiro. And the article was included in Tetrahedron Letters in 1982.Recommanded Product: 50767-78-7 The following contents are mentioned in the article:

The Et₃Al ate complexes of anions of RCH₂CH:CH₂ (I; R = Me₃Si, PhSe) reacted with carbonyl compounds at the α-position with high regioselectivity. E.g., lithiation of I (R = Me₃Si), followed by addition of Et₃Al and EtCHO gave 94% HOCHEtCH(SiMe₃)CH:CH₂. The stereoselective synthesis of (E)-CH₂:CHCH:CH(CH₂)₈OAc, a pheromone of Diparopsis castanea, by this method is reported. This study involved multiple reactions and reactants, such as (E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7Recommanded Product: 50767-78-7).

(E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 50767-78-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Carbon-13 NMR analyses on conjugated dienic pheromones of Lepidoptera was written by Ando, Tetsu;Kusa, Koji;Uchiyama, Masaaki;Yoshida, Shigeo;Takahashi, Nobutaka. And the article was included in Agricultural and Biological Chemistry in 1983.Computed Properties of C14H24O2 The following contents are mentioned in the article:

The ¹³C NMR of all the geometrical isomers of 5,7- and 8,10-dodecadien-1-ols and 9,11-dodecadienyl acetate were assigned from the examination of ¹³C chem. shift differences of olefinic C atoms induced by diene and chain substitution and by the chem. shift changes of allylic and olefinic C atoms due to geometry conversion of the conjugated diene system. These correlations comprise a new method for assigning the ¹³C NMR of conjugated systems. The ¹H NMR of the dienols and their derivatives were also discussed. This study involved multiple reactions and reactants, such as (E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7Computed Properties of C14H24O2).

(E)-Dodeca-9,11-dien-1-yl acetate (cas: 50767-78-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Computed Properties of C14H24O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Copper-Catalyzed Three-Component Germyl Peroxidation of Alkenes was written by Luo, Yani;Xu, Boxia;Lv, Leiyang;Li, Zhiping. And the article was included in Organic Letters in 2022.Synthetic Route of C7H6F6O2 The following contents are mentioned in the article:

The concurrent incorporation of a germyl fragment and another functional group (beyond the hydrogen atom) across the C=C double bond is a highly appealing yet challenging task. Herein, the efficient germyl peroxidation of alkenes with germanium hydrides and tert-Bu hydroperoxide via a copper-catalyzed three-component radical relay strategy is demonstrated. This protocol exhibits excellent functional group tolerance and exquisite chemo- and regioselectivity under mild conditions and represents a rare example of constructing synthetically challenging metal-embedded organic peroxides. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3Synthetic Route of C7H6F6O2).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Synthetic Route of C7H6F6O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ligand-Enabled, Iridium-Catalyzed ortho-Borylation of Fluoroarenes was written by Kuleshova, Olena;Asako, Sobi;Ilies, Laurean. And the article was included in ACS Catalysis in 2021.Synthetic Route of C14H18BFO4 The following contents are mentioned in the article:

A terpyridine derivative and an iridium complex catalyze the C-H borylation of a stoichiometric amount of a fluoroarene with high ortho-selectivity and tolerance of functional groups such as bromide, chloride, ester, ketone, amine, and in situ-borylated hydroxyl. Complex drug mols. such as haloperidol can be selectively borylated ortho to the F atom. The terpyridine ligand undergoes rollover cyclometalation to produce an N,N,C-coordinated iridium complex, which may either selectively borylate the fluoroarene by itself or undergo reductive elimination to produce a borylated ligand. This study involved multiple reactions and reactants, such as Methyl 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 1638847-77-4Synthetic Route of C14H18BFO4).

Methyl 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 1638847-77-4) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C14H18BFO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ligand-Enabled, Iridium-Catalyzed ortho-Borylation of Fluoroarenes was written by Kuleshova, Olena;Asako, Sobi;Ilies, Laurean. And the article was included in ACS Catalysis in 2021.Computed Properties of C14H18BFO4 The following contents are mentioned in the article:

A terpyridine derivative and an iridium complex catalyze the C-H borylation of a stoichiometric amount of a fluoroarene with high ortho-selectivity and tolerance of functional groups such as bromide, chloride, ester, ketone, amine, and in situ-borylated hydroxyl. Complex drug mols. such as haloperidol can be selectively borylated ortho to the F atom. The terpyridine ligand undergoes rollover cyclometalation to produce an N,N,C-coordinated iridium complex, which may either selectively borylate the fluoroarene by itself or undergo reductive elimination to produce a borylated ligand. This study involved multiple reactions and reactants, such as Methyl 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 1638847-77-4Computed Properties of C14H18BFO4).

Methyl 2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 1638847-77-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C14H18BFO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fluorinated hybrid polymers by copolymerization of trialkylsilyl methacrylate with fluoroalkyl methacrylate was written by Fujiwara, Hirotada;Narita, Tadashi;Hamana, Hiroshi;Shimizu, Koichi. And the article was included in Polymer Journal (Tokyo, Japan) in 2002.Application In Synthesis of 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate The following contents are mentioned in the article:

Fluorinated hybrid polymers bearing alkylsilyl groups were synthesized by copolymerization of tributylsilyl methacrylate (NBSM) with 2,2,2-trifluoroethyl or 1-trifluoromethyl-2,2,2-trifluoroethyl methacrylate (TFEM or HxFIM). To estimate the sequential distribution of monomer units in copolymers, monomer reactivity of NBSM with TFEM or HxFIM under radical (Bu peroxide as initiator) and anionic (LiZnBuEt₂ as initiator) polymerization conditions was studied by ¹H NMR. Surface characteristics of hybrid polymers were examined by contact angle measurements. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3Application In Synthesis of 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate).

1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application In Synthesis of 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and Properties of 4′-ThioLNA/BNA was written by Maeda, Rion;Saito-Tarashima, Noriko;Wakamatsu, Hideaki;Natori, Yoshihiro;Minakawa, Noriaki;Yoshimura, Yuichi. And the article was included in Organic Letters in 2021.Quality Control of Diphenyl carbonate The following contents are mentioned in the article:

To develop a new nucleoside analog applicable to oligonucleotide therapeutics, we designed a 4′-thio analog of an LNA/BNA monomer. Synthesis of 4′-hydroxymethyl-4′-thioribonucleoside was achieved by a tandem ring-contraction-aldol reaction of a 5-thiopyranose derivative and the subsequent Pummerer-type thioglycosylation reaction of the corresponding sulfoxide. Treatment of 4′-hydroxymethyl-4′-thiopyrimidine nucleosides with di-Ph carbonate in the presence of catalytic NaHCO₃ gave the desired 4′-thioLNA/BNA monomers, which were introduced into oligonucleotides. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Quality Control of Diphenyl carbonate).

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Quality Control of Diphenyl carbonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Variable-pressure infrared studies on the molecular flexibility of the model lubricant 2-ethylhexyl benzoate (EHB) was written by Whitley, Andrew;Yarwood, Jack;Gardiner, Derek J.. And the article was included in Journal of the Chemical Society, Faraday Transactions in 1993.Application of 5444-75-7 The following contents are mentioned in the article:

A liquid-phase high-pressure IR study of the model lubricant 2-ethylhexyl benzoate (EHB) between 0 and 40 kbar (at ambient temperature) is reported. Changes in band position and bandwidth were interpreted in terms of in-chain and lateral chain interactions with a net increase in the importance of repulsive potentials and an increase in the distribution of mol. environments. Although changes in the proportion of gauche conformers in the hydrocarbon chain would be expected at higher densities, evidence of such changes were difficult to find in the IR spectrum. This study involved multiple reactions and reactants, such as 2-Ethylhexyl benzoate (cas: 5444-75-7Application of 5444-75-7).

2-Ethylhexyl benzoate (cas: 5444-75-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 5444-75-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics