Tag: 200-300

Long-chain functionally substituted aromatic Schiff bases derived from cetylamine was written by Dikusar, E. A.;Potkin, V. I.;Kozlov, N. G.. And the article was included in Russian Journal of Organic Chemistry in 2009.Electric Literature of C12H14O4 This article mentions the following:

A series of long-chain functionally substituted aromatic Schiff bases I containing alkoxy and acyloxy groups, as well as carborane fragments, was synthesized by condensation of the corresponding benzaldehydes of the vanillin series with cetylamine. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4Electric Literature of C12H14O4).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Electric Literature of C12H14O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A thiourea-functionalized metal-organic macrocycle for the catalysis of Michael additions and prominent size-selective effect was written by Yang, Lu;Zhao, Liang;Zhou, Zhen;He, Cheng;Sun, Hui;Duan, Chunying. And the article was included in Dalton Transactions in 2017.Reference of 1190-39-2 This article mentions the following:

A discrete tetranuclear thiourea-based metal-organic macrocycle (MOM) with a large size was constructed by a well-designed organic ligands 1-(2-pyridylmethyleneamino)-3-[4-[4-[(2-pyridylmethyleneamino)carbamothioylamino]phenyl]sulfonylphenyl]thiourea (SPT) and 1-(2-pyridylmethyleneamino)-3-[3-[(2-pyridylmethyleneamino)carbamothioylamino]phenyl]thiourea (PDT) with nickel(II) ions via self-assembly. Incorporation of thiourea groups as hydrogen-bond donors into a metal-organic complex system led to a new approach for synthesis of functionalized heterogeneous catalysts, as this not only introduced coordination sites serving as chelators, but also overcomes the issues of self-association via intermol. H-bonding, often occurring in homogeneous systems. The packing structure of this material formed a confined environment suitable for the access of substrate mols. dragged by the strong hydrogen-bond interactions from the thiourea groups, thus achieving a high catalytic performance in Michael additions of β-nitrostyrenes to nitroalkanes I [R = C₆H₅, 4-ClC₆H₄, 4-MeC₆H₄, etc.], with remarkable yields and size-selectivity in heterogeneous phase. Moreover, a comparison of the IR spectrum of Ni-SPT with the spectra of di-Me malonate- and β-nitrostyrene-impregnated Ni-SPT indicated that both substrate mols., β-nitrostyrene and di-Me malonate, were able to access the cavity of the trimeric subunit. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Reference of 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Reference of 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Controlled Synthesis of Methacrylic Acid-Methyl Acrylate Copolymers and Their Properties at Various Interfaces was written by Zamyshlyayeva, O. G.;Ionychev, B. N.;Frolova, A. I.;Baten’kin, M. A.;Simonova, M. A.;Kopylova, N. A.;Zaitsev, S. D.;Semchikov, Yu. D.. And the article was included in Russian Journal of Applied Chemistry in 2019.Electric Literature of C14H12S2 This article mentions the following:

Conditions were found for controlled reversible addition-fragmentation chain-transfer radical polymerization to obtain narrow-dispersity gradient methacrylic acid-Me acrylate copolymer (Mn = 1.59 × 10⁴). A copolymer of similar composition and mol. mass (M_n = 1.81 × 10⁴) with random distribution of units was obtained by radical copolymerization in the presence of dodecyl mercaptan. The behavior of the gradient and random copolymers, each containing ∼14 mol% methacrylic acid units, was studied in solutions, Langmuir monolayers, and Langmuir-Blodgett films. Several ranges of the existence of associates and micelles, preserved upon transfer in a Langmuir-Blodgett film, were revealed for the narrow-dispersity copolymer at the water-air interface depending on pH of the subphase. Associates in the form of ribbon structures and mol. ensembles of nanometric size (network structure with loop-like fragments) are observed in the AFM images of Langmuir-Blodgett films of the gradient and random copolymers, resp. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Electric Literature of C14H12S2).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C14H12S2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Novel (3,5-di-tert-butyl-2-hydroxy-phenylcarbamoyl)-alkanoic acids as potent antioxidants was written by Lodyato, Vladimir I.;Yurkova, Irina L.;Sorokin, Viktor L.;Shadyro, Oleg I.;Dolgopalets, Vladimir I.;Kisel, Mikhail A.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2004.Recommanded Product: 12-Methoxy-12-oxododecanoic acid This article mentions the following:

A series of novel phenolic antioxidants, e.g., I, of amphiphilic structure has been synthesized. Investigations into the influence of aliphatic spacer length and nature of a hydrophilic anchor on the antioxidant activity allowed elucidating certain structure requirements for the membrane-addressed antioxidant designing. In the experiment, the researchers used many compounds, for example, 12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0Recommanded Product: 12-Methoxy-12-oxododecanoic acid).

12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Recommanded Product: 12-Methoxy-12-oxododecanoic acid

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Controlled Relay Process to Access N-Centered Radicals for Catalyst-free Amidation of Aldehydes under Visible Light was written by Lee, Wongyu;Jeon, Hyun Ji;Jung, Hoimin;Kim, Dongwook;Seo, Sangwon;Chang, Sukbok. And the article was included in Chem in 2021.Safety of 4-Formyl-2-methoxyphenyl isobutyrate This article mentions the following:

Here, a new relay process involving the slow in situ generation of a photoactive N-chloro species via C-N bond formation, which subsequently enables mild and selective access to N-centered radicals under visible light conditions was reported. The utility of this approach was demonstrated by the conversion of aldehydes to amides I [R¹ = t-Bu, cyclopropyl, Ph, etc.; R² = Boc, Cbz, Ts, etc.], employing N-chloro-N-sodio carbamates as a practical amidating source. This synthetic operation obviated the need for catalysts, external oxidants, and coupling reagents that were typically required in related processes, consequently allowed high functional group tolerance and excellent applicability for late-stage functionalization. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4Safety of 4-Formyl-2-methoxyphenyl isobutyrate).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of 4-Formyl-2-methoxyphenyl isobutyrate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Well-defined epoxide-containing styrenic polymers and their functionalization with alcohols was written by McLeod, David C.;Tsarevsky, Nicolay V.. And the article was included in Journal of Polymer Science, Part A: Polymer Chemistry in 2016.Recommanded Product: 27249-90-7 This article mentions the following:

Polymers containing electrophilic moieties, such as activated esters, epoxides, and alkyl halides, can be readily modified with a variety of nucleophiles to produce useful functional materials. The modification of epoxide-containing polymers with amines and other strong nucleophiles is well-documented, but there are no reports on the modification of such polymers with alcs. Using phenyloxirane and glycidyl butyrate as low mol. weight model compounds, it was determined that the acid-catalyzed ring-opening of aryl-substituted epoxides by alcs. to form β-hydroxy ether products was significantly more efficient than that of alkyl-substituted epoxides. An aryl epoxide-type styrenic monomer, 4-vinylphenyloxirane (4VPO), was synthesized in high yield using an improved procedure and then polymerized in a controlled manner under reversible addition-fragmentation chain-transfer (RAFT) polymerization conditions. A successful chain extension with styrene proved the high degree of chain-end functionalization of the poly4VPO-based macro chain transfer agent. Poly4VPO was modified with a library of alcs. and phenols, some of which contained reactive functionalities, e.g., azide, alkyne, allyl, etc., using either CBr₄ (in PhCN at 90 °C for 2-3 days) or BF₃ (in CH₂Cl₂ at ambient temperature over 30 min) as the catalyst. The resulting β-hydroxy ether-functionalized homopolymers were characterized using size exclusion chromatog., ¹H NMR and IR spectroscopy, and thermal gravimetric anal. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Recommanded Product: 27249-90-7).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 27249-90-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rh(III)-Catalyzed C(7)-H Alkylation of Quinolines in the Synthesis of Angular π-Extended Pyrroloquinolines for Single-Component White-Light Emission was written by Khot, Nandkishor Prakash;Mahato, Paritosh;Sajeev, T. K.;Mukherjee, Saptarshi;Kapur, Manmohan. And the article was included in Organic Letters in 2022.Category: esters-buliding-blocks This article mentions the following:

Reported herein is a sustainable approach for a regioselective Rh(III)-catalyzed C(7)-H alkylation of 8-aminoquinolines via metal carbene migratory insertion. This transformation displays a high functional group tolerance and exquisite site selectivity to afford the C-7 alkylated products I [R¹ = H, 2-Me, 3-Br, etc., R² = Me, Et, Ar = Ph, 4-FC₆H₄, 2-furyl, etc.]. These products were derivatized to afford π-extended angular pyrroloquinolines II [R³ = H, Me, R⁴ = H, 7-(4-HOC₆H₄), 7-(4-MeOC₆H₄), Ar¹ = Ph, 3-FC₆H₄, 2-thienyl, etc.], one of which, II [R³ = R⁴ = H, Ar = 2-thienyl], showed white-light emission (WLE) with CIE coordinates (0.26, 0.34). An excellent cell viability and in vivo cellular imaging substantiated the nontoxic nature of these compounds In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Category: esters-buliding-blocks).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vaporization/sublimation enthalpies of mono- and dimethyl-esters estimated by solution calorimetry method was written by Samatov, Aizat A.;Nagrimanov, Ruslan N.;Miroshnichenko, Evgeniy A.;Solomonov, Boris N.. And the article was included in Thermochimica Acta in 2020.Formula: C12H22O4 This article mentions the following:

The additive scheme for calculating the solvation enthalpies of aliphatic compounds has been developed for linear mono- and dimethyl-esters. Ester group contribution to the enthalpy of solvation in n-heptane was obtained. Accuracy of the proposed approach for determination of solvation enthalpies of linear mono- and dimethyl-esters was tested by comparison with exptl. solvation enthalpies. In most cases, deviations do not exceed 1 kJ·mol^-1. It was found that the dependence of the solution enthalpies of mono- and dimethyl-esters on the number of carbon atoms in the mol. can be fitted by power function. This dependence and a group-additivity scheme for solvation enthalpy were used for estimation of the enthalpies of phase transitions of mono- and dimethyl-esters. Evaluated values of sublimation, vaporization, and fusion enthalpies at 298.15 K are in good agreement with exptl. data obtained by conventional methods. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Formula: C12H22O4).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Formula: C12H22O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Functionalization and patterning of reactive polymer brushes based on surface reversible addition and fragmentation chain transfer polymerization was written by Choi, Jiyeon;Schattling, Philipp;Jochum, Florian D.;Pyun, Jeffrey;Char, Kookheon;Theato, Patrick. And the article was included in Journal of Polymer Science, Part A: Polymer Chemistry in 2012.Related Products of 27249-90-7 This article mentions the following:

We present the synthesis of reactive polymer brushes prepared by surface reversible addition-fragmentation chain transfer polymerization of pentafluorophenyl acrylate. The reactive ester moieties can be used to functionalize the polymer brush film with virtually any functionality by simple post-polymerization modification with amines. Dithiobenzoic acid benzyl-(4-ethyltrimethoxylsilyl) ester was used as the surface chain transfer agent (S-CTA) and the anchoring group onto the silicon substrates. Reactive polymer brushes with adjustable mol. weight, high grafting d., and conformal coverage through the grafting-from approach were obtained. Subsequently, the reactive polymer brushes were converted with amino-spiropyrans resulting in reversible light-responsive polymer brush films. The wetting behavior could be altered by irradiation with UV or visible light. Furthermore, a patterned surface of polymer brushes was obtained using a lithog. technique. UV irradiation of the S-CTA-modified substrates leads to a selective degradation of S-CTA in the exposed areas and gives patterned activated polymer brushes after a subsequent RAFT polymerization step. Conversion of the patterned polymer brushes with 5-((2-aminoethyl)amino)naphthalene-1-sulfonic acid resulted in patterned fluorescent polymer brush films. The utilization of reactive polymer brushes offers an easy approach in the fabrication of highly functional brushes, even for functionalities whose introduction is limited by other strategies. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Related Products of 27249-90-7).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Related Products of 27249-90-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Click chemistry-based synthesis and cytotoxic activity evaluation of 4α-triazole acetate podophyllotoxin derivatives was written by Hou, Wei;Zhang, Guanjun;Luo, Zhi;Su, Lin;Xu, Hongtao. And the article was included in Chemical Biology & Drug Design in 2019.Application In Synthesis of tert-Butyl (3-ethynylphenyl)carbamate This article mentions the following:

A series of novel 4α-triazole acetate podophyllotoxin derivatives were synthesized via click chem. In vitro cytotoxic activity evaluation showed that most of the derivatives exhibited potent inhibitory activities against the tested cancer cell lines with low nanomolar IC₅₀ values. Further studies demonstrated that compound I exhibited broad-spectrum cytotoxic activities, effectively overcame drug-resistance, and showed relatively weak cytotoxicity on non-cancer cells. Preliminary mechanistic studies indicated that I might have action on microtubule, cause cell cycle arrest at G₂/M phase, and induce apoptosis in human PC-3 cancer cells. In the experiment, the researchers used many compounds, for example, tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3Application In Synthesis of tert-Butyl (3-ethynylphenyl)carbamate).

tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of tert-Butyl (3-ethynylphenyl)carbamate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics