Tag: 200-300

Enantioselective Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones through Organocatalytic Transfer Hydrogenation of 2-Hydroxypyrimidines was written by Meng, Fan-Jie;Shi, Lei;Feng, Guang-Shou;Sun, Lei;Zhou, Yong-Gui. And the article was included in Journal of Organic Chemistry in 2019.Quality Control of Ethyl 3-oxo-3-(m-tolyl)propanoate This article mentions the following:

Chiral phosphoric acid-catalyzed transfer hydrogenation of 2-hydroxypyrimidines has been successfully realized using Hantzsch ester or dihydrophenanthridine as the hydrogen source, furnishing the chiral 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) with excellent yields and enantioselectivities of �9%. Notably, a novel kind of chiral DHPMs with an alkyl stereogenic center can be prepared through highly chemoselective transfer hydrogenation. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Quality Control of Ethyl 3-oxo-3-(m-tolyl)propanoate).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of Ethyl 3-oxo-3-(m-tolyl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Base initiated aromatization/C-O bond formation: a new entry to O-pyrazole polyfluoroarylated ethers was written by Tang, Xiangyang;Chang, Jing;Liu, Cuibo;Zhang, Bin. And the article was included in Tetrahedron Letters in 2014.Computed Properties of C12H14O3 This article mentions the following:

A base initiated intermol. S_NAr reaction of pyrazolones with polyfluoroarenes was developed. The process involved the isomerization aromatization of pyrazolone followed by the C-O bond formation via the selective C-F bond cleavage. With this strategy, a wide range of O-pyrazole polyfluoroarylated ethers bearing diverse functional groups were synthesized in mild to good yields. Addnl., our method was also applied to the isoxazole substrates. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Computed Properties of C12H14O3).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Computed Properties of C12H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zinc perchlorate hexahydrate catalyzed mono- and bis-transesterification of malonic esters was written by Tural, Servet. And the article was included in Turkish Journal of Chemistry in 2008.Name: malonic acid dibutyl ester This article mentions the following:

Com. available zinc perchlorate hexahydrate [Zn(ClO₄)₂.6H₂O] was found to be a highly effective catalyst for the transesterification of malonic esters with alcs. The treatment of methyl-, ethyl-, or α-substituted malonic esters with primary or secondary alcs. in the presence of a catalytic amount of zinc perchlorate results in good to high yields of the corresponding esters (68%-99%). Mono-transesterification products are also obtained in moderate to good yields (22%-42%). The reaction was also carried out with 2-mono- and di-substituted malonic esters, and in this case the reaction time is, in some cases, shorter, in which the yields are comparable with unsubstituted derivatives The cyanomethyl and bis-cyanomethyl malonic ester derivatives are also used for transesterification and the corresponding products are obtained in high yields. No reaction occurs with the CN group during the reaction. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Name: malonic acid dibutyl ester).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Name: malonic acid dibutyl ester

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Controlled spatial dispersion of CdSe tetrapod nanocrystals with amphiphilic block copolymer particles was written by Seo, Seok Kyoo;Lim, Jeewoo;Lee, Hyemin;Heo, Hyeonjun;Char, Kookheon. And the article was included in Polymer in 2016.Product Details of 27249-90-7 This article mentions the following:

We report, for the first time, a nanoscale control of the spatial distribution of semiconducting tetrapod (TP) nanocrystals within block copolymer particles. Polystyrene (PS) block copolymer (BCP)/CdSe TP nanocrystal hybrid particles were prepared by the nanopptn. of TP/BCP mixtures into methanol. The BCPs consisted of short, polar terminal block bearing Me disulfide anchoring moiety which serves both to bind to CdSe TP surfaces as well as to drive self-assembly during nanopptn. into polar solvent systems. The resulting BCP/TP hybrid particles showed various spatial distribution and the number d. of TPs with respect to individual polymer particles depending on the d.p. of the block copolymer as well as the nature of the solvent in which nanopptn. was done. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Product Details of 27249-90-7).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 27249-90-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rhodium(I)-Catalyzed Coupling-Cyclization of C=O Bonds with α-Diazoketones was written by Chen, Ziyang;Hu, Xinwei;Huang, Junmin;Zeng, Wei. And the article was included in Organic Letters in 2018.Formula: C12H14O3 This article mentions the following:

An unprecedented intermol. nucleophilic attack of C=X bonds (X = O and S) on the rhodium(I)-carbenes has been developed. This transformation allows for the coupling-cyclization of aroylamides with α-diazoketones and provides concise access to 2,4,5-trisubstituted 1,3-oxazoles, e.g., I, and 1,3-thiazoles, e.g., II, with a broad tolerance of functional groups. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Formula: C12H14O3).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Formula: C12H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Oxyfunctionalization of Active Methylene Compounds Using Sodium Chlorite in Water was written by Kitanosono, Taku;Tani, Shinki;Kobayashi, Shu. And the article was included in Asian Journal of Organic Chemistry in 2018.Electric Literature of C11H20O4 This article mentions the following:

A methylene group inserted between proximal carbonyl groups underwent exclusive oxyfunctionalization with sodium chlorite in the presence of redox-inert Hf^IV in water. Although alternative routes involving prior α-functionalization can be executed under mild conditions, preparatively valuable oxidation methods that deliver high levels of both conversion and selectivity remain a prized goal from the standpoint of streamlining organic synthesis. Chlorine dioxide, which was generated as a yellowish gas during the reaction, is considered to be a bona fide oxidant against active methylene compounds The pivotal role of water was clear, given that the reaction was significantly retarded in both aqueous acetonitrile and ethanol, which can solubilize sodium chlorite. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Electric Literature of C11H20O4).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C11H20O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A Photocatalyzed Synthesis of Naphthalenes by Using Aniline as a Traceless Directing Group in [4 + 2] Annulation of Amino-benzocyclobutenes with Alkynes was written by Wang, Qile;Zheng, Nan. And the article was included in ACS Catalysis in 2017.Application In Synthesis of tert-Butyl (3-ethynylphenyl)carbamate This article mentions the following:

A visible-light-promoted synthesis of substituted naphthalenes via [4 + 2] annulation of amino-benzocyclobutenes with alkynes is reported. Amino-benzocyclobutenes, which are conveniently synthesized by [2 + 2] cycloaddition of arynes with ketenes followed by reductive amination, undergo regioselective opening of the cyclobutenyl ring to reveal a presumably distonic radical cation upon photooxidation by an excited iridium complex. The distonic radical cation undergoes the annulation with terminal and internal alkynes as well as diynes to afford structurally diverse naphthalenes. The regiochem. of the annulation follows the pattern displayed in the addition of nucleophilic carbon radicals to alkynes. The aniline group plays a dual role in which it not only directs the initial photooxidation to generate the amine radical cation but also serves as a leaving group to complete aromatization. In the experiment, the researchers used many compounds, for example, tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3Application In Synthesis of tert-Butyl (3-ethynylphenyl)carbamate).

tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application In Synthesis of tert-Butyl (3-ethynylphenyl)carbamate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dichloroethylaluminum-catalyzed reactions of alkenes with electrophilic cyclopropanes. A new cyclopentane annelation reaction was written by Beal, Richard B.;Dombroski, Mark A.;Snider, Barry B.. And the article was included in Journal of Organic Chemistry in 1986.Recommanded Product: 10203-58-4 This article mentions the following:

Reactions of cyclopropanedicarboxylates I (R, R¹ = H, Me) with alkenes and EtAlCl₂ were studied. Treatment of 1,1-di-, tri-, and tetrasubstituted alkenes with I (R = R¹ = Me) and 2 equiv of EtAlCl₂ gives zwitterions which collapse to cyclopentanedicarboxylates in good to excellent yield. This reaction provides a general procedure for the annulation of cyclopentanes to alkenes. Thus, methylenecyclohexane and 1-methylcyclohexene reacted with I and EtAlCl₂ to afford 98% spiro compound II and 60% bicyclic compound III, resp. The intermediate zwitterions undergo the 1,2-hydride and 1,2-Me shifts characteristic of carbocations, although these side reactions are generally minor. I (R = H, R¹ = Me) reacts similarly with alkenes at the more substituted carbon to give 3-methylcyclopentane-1,1-dicarboxylates. I (R = R¹ = Me) rearranges in the presence of EtAlCl₂ to di-Et isobutylidenemalonate, which reacts with alkenes and is reduced by EtAlCl₂. The intramol. Lewis acid-induced addition of alkenes to cyclopropanedicarboxylate esters occurs analogously. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Recommanded Product: 10203-58-4).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: 10203-58-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Crystal structure of tetramethyl 5,5′-(buta-1,3-diyne-1,4-diyl)diisophthalate, C₂₄H₁₈O₈ was written by Lu, Xinhua;Hu, Jin;Zhu, Caixia. And the article was included in Zeitschrift fuer Kristallographie – New Crystal Structures in 2018.HPLC of Formula: 313648-56-5 This article mentions the following:

C₂₄H₁₈O₈, monoclinic, P2₁/n (number 14), a = 3.9930(7) Å, b = 26.483(5) Å, c = 10.3307(19) Å, β = 98.136(4)°, V = 1081.5(3) ų, Z = 2, R_gt(F) = 0.0606, wR_ref(F²) = 0.1986, T = 293(2) K. In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5HPLC of Formula: 313648-56-5).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. HPLC of Formula: 313648-56-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Elucidation of the Key Role of [Ru(bpy)₃]²⁺ in Photocatalyzed RAFT Polymerization was written by Christmann, Julien;Ibrahim, Ahmad;Charlot, Vincent;Croutxe-Barghorn, Celine;Ley, Christian;Allonas, Xavier. And the article was included in ChemPhysChem in 2016.Recommanded Product: Benzyl benzodithioate This article mentions the following:

Photocatalysis reactions using [Ru^II(bpy)₃]²⁺ were studied on the example of visible-light-sensitized reversible addition-fragmentation chain transfer (RAFT) polymerization Although both photoinduced electron- and energy-transfer mechanisms are able to describe this interaction, no definitive exptl. proof has been presented so far. This paper investigates the actual mechanism governing this reaction. A set of RAFT agents was selected, their redox potentials measured by cyclic voltammetry, and relaxed triplet energies calculated by quantum mechanics. Gibbs free-energy values were calculated for both electron- and energy-transfer mechanisms. Quenching rate constants were determined by laser flash photolysis. The results undoubtedly evidence the involvement of a photoinduced energy-transfer reaction. Controlled photopolymerization experiments are discussed in the light of the primary photochem. process and photodissociation ability of RAFT agent triplet states. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Recommanded Product: Benzyl benzodithioate).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Recommanded Product: Benzyl benzodithioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics