Tag: 200-300

The freezing temperature of organic substances was written by Serwy, H.. And the article was included in Bulletin des Societes Chimiques Belges in 1933.Application of 1190-39-2 This article mentions the following:

A tabulation of precise measurements of phys. properties of pure substances. Cl(CH₂)₃Cl, m. -99.5°, b. 120.4°; Cl(CH₂)₅Cl, m. -72.8°; b. 182.3°; d₄ 1.11622, d₄¹⁵ 1.10158, d₄³⁰ 1.08692; viscosity 1928 at 15°, 1481 at 30°; ns at 15° n He red 1.45858, n_α 1.45903, n He yellow 1.46161, n He green 1.46675, nβ 1.46801, n He blue 1.47189, n_γ 1.47681; Br(CH₂)₃Br, m. -34.2°, b. 167.34°; d₄ 2.01618, 1.98927 and 1.96238; viscosities 2241 and 1746; ns 1.52121, 1.52174, 1.52546, 1.53252, 1.53416, 1.53932 and 1.54464; Br(CH₂)₅Br, m. -39.5°, b. 222.3°, b₁₂ 99°; d₄ 1.72952, 1.70876 and 1.68788; viscosities 3888 and 2818; ns 1.50908, 1.50960, 1.51311, 1.51970, 1.52131, 1.52634 and 1.53072; NC(CH₂)₃CN, m. -29.45°, b₂₂ 160.4°, d₄ 1.00293, 0.99112 and 0.97930; viscosities 8104 and 5226; ns 1.43426, 1.43461, 1.43699, 1.44137, 1.44242, 1.44573 and 1.45048; NC(CH₂)₅CN, m. -31.4°, b_14.6 177.8°; d₄ 0.96181, 0.95070 and 0.93961; viscosities 9080 and 5501; ns 1.44010, 1.44044, 1.44278, 1.44721, 1.44816, 1.45167 and 1.45721; HO₂CCH₂CO₂H, m. 134.8-.9°; HO₂C(CH₂)₃CO₂H, m. 98.0-.1°; HO₂C(CH₂)₄CO₂H, m. 153.0.1°; HO₂C(CH₂)₅CO₂H, m. 105.7-.8°; EtO₂C(CH₂)₃CO₂Et, m. -23.80°, b. 233.68°, b₁₃ 117.6°; d₄ 1.04202, 1.02704 and 1.01210; viscosities 3260 and 2311; ns 1.42294, 1.42333, 1.42570, 1.42982, 1.43086, 1.43382 and 1.43820; EtO₂C(CH₂)₄CO₂Et m. -19.9°, b₁₃ 131°; d₄ 1.02589, 1.01165 and 0.99744; viscosities 3871 and 2648; ns 1.42673, 1.42708, 1.42924, 1.43362, 1.43463, 1.43783 and 1.44335; PrO₂CCH₂CO₂Pr, m. about -95°, b. 229.2°, b₁₃ 113°; d₄ 1.02929, 1.01453, 0.99977; viscosities 3161 and 2236; ns 1.41967, 1.42010, 1.42243, 1.42660, 1.42768, 1.43092 and 1.43569; PrO₂C(CH₂)₃CO₂Pr, m. -45.5°, b. 264.9°, b₁₃ 142.4°; d₄ 1.00766, 0.99385, 0.98001; viscosities 4437 and 3033; ns 1.42723, 1.42760, 1.42999, 1.43420, 1.43521, 1.43848 and 1.44144; PrO₂C(CH₂)₅CO₂Pr, m. -34°, b₁₃ 165.8°; d₄ 0.98676, 0.97371, 0.97074; viscosities 5017 and 4019; ns 1.43224, 1.43247, 1.43485, 1.43914, 1.44015, 1.44312 and 1.44890; BuO₂CCH₂CO₂Bu, m. -83°, b. 251.5°, b₁₃ 137.4°; d₄ 0.99930, 0.98560 and 0.97191; viscosities 3873 and 2682; ns, 1.42520, 1.42664, 1.42792, 1.43218, 1.43324, 1.43658 and 1.44133; BuO₂C(CH₂)₃CO₂Bu, m. -50.6°, b. 292.8°, b₁₃ 162.9°; d₄ 0.98534, 0.97227 and 0.95922; viscosities 5424 and 3659; ns 1.43147, 1.43189, 1.43426, 1.43845, 1.43955, 1.44279 and 1.44443; BuO₂C(CH₂)₅CO₂Bu, m. -30.5°, b_13.6 188.6°; d₄ 0.97509, 0.96295 and 0.95084; viscosities 8214 and 5262; ns 1.43460, 1.43673, 1.43910, 1.44344, 1.44445, 1.44771 and 1.45283; AmO₂CCO₂Am, m. -9°, b_14.8 154.1°; d₄ 0.98404, 0.97059 and 0.95718; viscosities 4983 and 3330; ns 1.42789, 1.42825, 1.43063, 1.43507, 1.43606, 1.43934 and 1.44496; AmO₂CCH₂CO₂Am, m. -60.0°, b_13.4 162.4°; d₄ 0.97853, 0.96550 and 0.95254; viscosities 5297 and 3562; ns 1.43041, 1.43080, 1.43316, 1.43748, 1.43847, 1.44180, 1.44293; AmO₂C(CH₂)₃CO₂Am, m. -35.1°, b_13.6 186.8°; d₄ 0.97607, 0.96367 and 0.95133; viscosities 8375 and 5308; ns 1.43597, 1.43631, 1.43868, 1.44313, 1.44411, 1.44740 and 1.45293; AmO₂C(CH₂)₅CO₂Am, m. -28.9°, b_17.4 213.4-3.5°; d₄ 0.95879, 0.94671 and 0.93471; viscosities 9428 and 5911. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Application of 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application of 1190-39-2

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A new procedure for the synthesis of barbituric acid was written by Dick, J.;Drugarin, C.. And the article was included in Acad. Rep. Populare Romine, Baza Cercetari Stiint. Timisoara, Studii. Cercetari Stiinte Chim. in 1961.Related Products of 1190-39-2 This article mentions the following:

A mixture of 120 g. butanol, 50 g. malonic acid, and 3.7 g. H₂SO₄ is refluxed two hours to yield 72.5% pure dibutyl malonate (I), n²⁰_D 1.4255, d₂₀ 1.0005. I (15 g.) and 6 g. urea in 50 g. butanol is added to 50 g. butanol containing 2 g. Na; the mixture is refluxed two hrs., cooled to 70° 80 g. H₂O and 10 g. HCl added, and the mixture further cooled to 40° and filtered to yield 73% barbituric acid (II). In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Related Products of 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Related Products of 1190-39-2

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Poly(N-isopropylacrylamide) capped plasmonic nanoparticles as resonance intensity-based temperature sensors with linear correlation was written by Liu, Yiyi;Dai, Xiaohui;Mallawaarachchi, Sudaraka;Hapuarachchi, Harini;Shi, Qianqian;Dong, Dashen;Thang, San H.;Premaratne, Malin;Cheng, Wenlong. And the article was included in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2017.Recommanded Product: 27249-90-7 This article mentions the following:

Thermosensitive polymer capped plasmonic nanoparticles are novel thermal nanofluids with potential sensing applications. Previous research efforts were focused only on monitoring plasmonic resonance peak shifts caused by aggregation as temperature varied. However, to date, no linear relation between the resonance peak shift and temperature was established. Here, the authors systematically study how plasmonic resonance peak intensity responds to solution temperature using poly(N-isopropylacrylamide)-capped Au nanorods (AuNRs) and nanobipyramids (AuNBPs) under aggregation-free conditions. Results clearly reveal the linear correlation between longitudinal resonance peak intensity and solution temperature for both types of particles. AuNBPs have sharper ends than AuNRs, resulting in greater thermo-sensitivity due to the presence of stronger hot spots. Further anal. and numerical studies demonstrate chem. interface damping effects by surface-capping ligand configurational changes and these theor. results agree well with exptl. observations. This damping-based sensing is reversible with excellent durability, indicating the possibility of potential real-world temperature sensing applications. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Recommanded Product: 27249-90-7).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: 27249-90-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Isosteric Substitution of 4H-1,2,4-Triazole by 1H-1,2,3-Triazole in Isophthalic Derivative Enabled Hydrogel Formation for Controlled Drug Delivery was written by Haering, Marleen;Rodriguez-Lopez, Julio;Grijalvo, Santiago;Tautz, Markus;Eritja, Ramon;Martin, Victor S.;Diaz Diaz, David. And the article was included in Molecular Pharmaceutics in 2018.Computed Properties of C12H10O4 This article mentions the following:

In this work, we demonstrated that the simple substitution of the 1,2,4-triazole moiety in 5-(4H-1,2,4-triazol-4-yl)isophthalic acid (5-TIA) by the 1H-1,2,3-triazol-5-yl unit enables the preparation of a hydrogelator (click-TIA). In sharp contrast to 5-TIA, its isostere click-TIA undergoes self-assembly in water upon sonication, leading to the formation of stable supramol. viscoelastic hydrogels with a critical gelation concentration of 6 g/L. Hydrogels made of click-TIA as well as hybrid hydrogels made of the mixture click-TIA + 5-TIA (molar ratio 1:0.2) were used to compare different properties of the materials (i.e., rheol. properties, thermal properties, mech. stability, morphol.). In terms of toxicity, neither click-TIA nor 5-TIA showed cytotoxic effects on cellular viability of HeLa cells up to 2.3 × 10^-3 g/L when compared to untreated cells incubated with DMSO. Furthermore, the hydrogels were used for the encapsulation and in vitro controlled release of oxytetracycline that followed first-order kinetics. For the hydrogel made of click-TIA, a maximum drug release of âˆ?0% was reached after âˆ? h within a pH range between 6.5 and 10. However, the release rate was reduced to approx. half of its value at pH values between 1.2 and 5.0, whereas the use of hybrid hydrogels made of click-TIA + 5-TIA allowed to reduce the original rate at pH â‰?6.5. In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Computed Properties of C12H10O4).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C12H10O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Catalytic dynamic kinetic resolutions with N-heterocyclic carbenes: Asymmetric synthesis of highly substituted β-lactones was written by Cohen, Daniel T.;Eichman, Chad C.;Phillips, Eric M.;Zarefsky, Emily R.;Scheidt, Karl A.. And the article was included in Angewandte Chemie, International Edition in 2012.Safety of Ethyl 3-oxo-3-(m-tolyl)propanoate This article mentions the following:

A new NHC-catalyzed (N-heterocyclic carbenes) DKR (dynamic kinetic resolution) with β-keto esters to generate highly substituted β-lactones with excellent levels of stereoselectivity has been developed. This process takes advantage of the conditions necessary to generate the active NHC catalyst to simultaneously promote the epimerization of a β-ketoester substrate. The present study provides efficient access to highly enantioenriched β-lactones and cyclopentenes in good yield with good to excellent diastereoselectivity. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Safety of Ethyl 3-oxo-3-(m-tolyl)propanoate).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of Ethyl 3-oxo-3-(m-tolyl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Amphiphilic mPEG-block-poly (profen amide-co-esters) copolymers: One pot biocatalytic synthesis, self-assembly in water and drug release was written by Qian, Xueqi;Wu, Qi;Xu, Fangli;Lin, Xianfu. And the article was included in Polymer in 2011.Reference of 106-79-6 This article mentions the following:

We developed a three-component, one pot biocatalytic polymerization to prepare amphiphilic diblock methoxy poly(ethylene glycol)-b-poly(profen amide-co-esters) (mPEG-PPAE) copolymers under the catalysis of Novozym-435 performed in di-Ph ether at 85° in vacuum for 48 h. 13 mPEG-PPAE copolymers with different profens, dicarboxylates, or PEG were designed and prepared as carriers for the sustained release of the ketoprofen, naproxen and ibuprofen amides. Their structure was characterized by FT-IR, ¹H NMR, and GPC measurements. These copolymers can readily self-assemble into nanosized micelles with the well dispersed sphere in aqueous solution, which were confirmed by DLS and TEM. The size of the micelles was influenced by the copolymer concentrations, and the higher copolymer concentration lead to the smaller size. The in vitro ibuprofen amide sustained release behavior indicated that the copolymer is highly sensitive to acid environment, and the release of ibuprofen amide can be effectively controlled. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Reference of 106-79-6).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Reference of 106-79-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Metabolism-Guided Design of Short-Acting Calcium-Sensing Receptor Antagonists was written by Southers, James A.;Bauman, Jonathan N.;Price, David A.;Humphries, Paul S.;Balan, Gayatri;Sagal, John F.;Maurer, Tristan S.;Zhang, Yan;Oliver, Robert;Herr, Michael;Healy, David R.;Li, Mei;Kapinos, Brendon;Fate, Gwendolyn D.;Riccardi, Keith A.;Paralkar, Vishwas M.;Brown, Thomas A.;Kalgutkar, Amit S.. And the article was included in ACS Medicinal Chemistry Letters in 2010.COA of Formula: C15H21BO4 This article mentions the following:

As part of a strategy to deliver short-acting calcium-sensing receptor (CaSR) antagonists, the metabolically labile thiomethyl functionality was incorporated into the zwitterionic amino alc. derivative I with the hope of increasing human clearance through oxidative metabolism, while delivering a pharmacol. inactive sulfoxide metabolite. The effort led to the identification of thioanisoles II (R = H, F) as potent and orally active CaSR antagonists with a rapid onset of action and short pharmacokinetic half-lives, which led to a rapid and transient stimulation of parathyroid hormone in a dose-dependent fashion following oral administration to rats. On the basis of the balance between target pharmacol., safety, and human disposition profiles, compounds II were advanced as clin. candidates for the treatment of osteoporosis. In the experiment, the researchers used many compounds, for example, Methyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 525362-07-6COA of Formula: C15H21BO4).

Methyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 525362-07-6) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C15H21BO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The synthesis and herbicidal activity of 1-alkyl-3-(α-hydroxybenzylidene)pyrrolidine-2,4-diones was written by Zhu, You-Quan;Yao, Chang-Sheng;Zou, Xiao-Mao;Hu, Fang-Zhong;Liu, Bin;Li, Yong-Hong;Yang, Hua-Zheng. And the article was included in Molecules in 2005.Product Details of 33166-79-9 This article mentions the following:

Title compounds I (R¹ = 3-NO₂, 4-NO₂, 2-Me, 3-Me, 4-Me, 2-MeO, 4-MeO, 2-Cl, 4-Cl; R² = Me, CHMe₂, CMe₃) were prepared by cyclocondensation of R¹C₆H₄COCH₂COOEt with R²NHCH₂COOEt. Preliminary bioassay results indicated that some of products have high herbicidal activity against annual dicotyledonous and monocotyledonous plants. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Product Details of 33166-79-9).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Product Details of 33166-79-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Time-resolved electron spin resonance observations of the initial stages of conventional and controlled radical polymerization processes was written by Kajiwara, Atsushi. And the article was included in ACS Symposium Series in 2018.Recommanded Product: 27249-90-7 This article mentions the following:

Structural and kinetic investigations of radicals formed in the early stage of polymerizations have been conducted by the ESR technique with various time resolutions Time-resolved ESR observations of water-soluble (meth)acrylate radicals formed in aqueous phase free-radical polymerization and controlled radical polymerization systems were conducted. These measurements had not been examined previously in spite of their fundamental importance in understanding the initiation procedures in radical polymerizations Clear and well-resolved TR ESR spectra of sodium (meth)acrylates in water were observed and the structures and mol. dynamics of the radicals formation and reactions were discussed. TR ESR spectroscopy was also applied to the RAFT controlled radical polymerization and the sequential radical addition reactions in the initial stage of the RAFT polymerizations were observed In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Recommanded Product: 27249-90-7).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 27249-90-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Exchange of Substituents between (Macro)Alkoxyamines and (Macro)RAFT Agents (ESARA): A Bridge between Nitroxide-Mediated and RAFT Controlled Radical Polymerization Techniques was written by Favier, Arnaud;Luneau, Benoit;Vinas, Jerome;Laissaoui, Nasrine;Gigmes, Didier;Bertin, Denis. And the article was included in Macromolecules (Washington, DC, United States) in 2009.Related Products of 27249-90-7 This article mentions the following:

Developing new tools to combine different polymerization techniques significantly extends the possibilities in terms of polymer design. Here, we report on a radical process abbreviated ESARA that creates a bridge between two controlled radical polymerization (CRP) techniques, nitroxide-mediated polymerization (NMP) and reversible addition-fragmentation chain transfer polymerization (RAFT). Proof of concept was first obtained with low mol. weight compounds Alkoxyamine and thiocarbonylthio control agents were shown to exchange their resp. substituents in selected exptl. conditions, opening the way for the synthesis of new original control agents. The ESARA process was then implemented at the macromol. level. Polystyryl macroalkoxyamines were converted to the corresponding polystyryl macroRAFT agents using thiocarbonylthio compounds In addition, polystyryl macroRAFT agents were converted back to polystyryl macroalkoxyamine after reaction with an alkoxyamine. The bridge created between the two CRP techniques offers an access to a large number of well-defined polymer architectures such as block copolymers that would be difficult to obtain by only one technique. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Related Products of 27249-90-7).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 27249-90-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics