Tag: 200-300

One-pot ozonolytic synthesis of acyclic α,ω-bifunctional compounds from methyl 10-undecenoate and 10-undecen-1-ol was written by Legostaeva, Yu. V.;Botsman, L. P.;Nazarov, I. S.;Yakovleva, M. P.;Garifullina, L. R.;Khalikov, R. M.;Ishmuratov, G. Yu.. And the article was included in Russian Journal of Applied Chemistry in 2015.Category: esters-buliding-blocks This article mentions the following:

Transformations of peroxy products formed by ozonolysis of undecylenic acid derivatives (Me ester and hydride reduction product, 10-undecen-1-ol) in various protic and aprotic solvents (MeOH, PrⁱOH, THF, 1: 5 AcOH-CH₂Cl₂ mixture), occurring under the action of such reductants as hydroxylamine and semicarbazide hydrochlorides, were studied. These reductants exhibit high performance and in some cases high chemoselectivity, which allowed the development of a number of one-pot procedures for the synthesis of acyclic α,ω-bifunctional compounds, the majority of which are widely used in medicine, perfumery, cosmetics, engineering, and chem. industry, e.g., as block synthons in targeted organic synthesis. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Category: esters-buliding-blocks).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Aggregation behavior of polystyrene-b-poly(acrylic acid) at the air-water interface was written by Wang, Xiaolu;Ma, Xiaoyan;Zang, Duyang. And the article was included in Soft Matter in 2013.Recommanded Product: Benzyl benzodithioate This article mentions the following:

The aggregation behavior of amphiphilic block copolymer polystyrene-b-poly(acrylic acid) (PS-b-PAA) at the air-water interface was investigated through surface pressure measurements (isotherms, compression-expansion hysteresis and compression relaxation experiments), Brewster Angle Microscopy (BAM) imaging and Atomic Force Microscopy (AFM) imaging. It is found that PS-b-PAA (M_n = 11 490 g mol^-1, PAA wt%∼62%) forms a stable Langmuir monolayer on the water surface (pH = 7) by using N,N-dimethylformamide (DMF) as the spreading solvent. The aggregation of block copolymer is induced by an initial diffusion of DMF into water from the interface. Upon compression of the film, the pseudoplateau observed in the Langmuir isotherm corresponds to a “pancake-to-brush” transition with the PAA chains gradually dissolving in the water subphase and stretching underneath the PS cores. Based on the isotherms and the BAM images, it is suggested that the polymer chain dynamics in spreading solutions with different concentrations at the time of solvent diffusion influence the interfacial behavior of block copolymers significantly. The Langmuir-Blodgett (LB) films prepared at different surface pressures from different spreading solution concentrations were scanned by AFM. A variety of morphologies such as wormlike, porous and reticulate structures, and dots were observed The isotherms and AFM images show the spreading solution concentration and surface pressure dependence of the aggregation behavior of PS-b-PAA copolymer at the air-water interface. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Recommanded Product: Benzyl benzodithioate).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: Benzyl benzodithioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Three-component coupling using arynes and DMF: straightforward access to coumarins via ortho-quinone methides was written by Yoshida, Hiroto;Ito, Yu;Ohshita, Joji. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2011.SDS of cas: 1190-39-2 This article mentions the following:

ortho-Quinone methides, arising from a formal [2+2] cycloaddition between arynes and DMF, were found to facilely undergo a [4+2] cycloaddition with ester enolates or ketenimine anions to produce diverse coumarins in a straightforward manner. E.g., coumarin derivative I was prepared with 79% yield by reacting CH₂(CO₂Et)₂ and F₃CSO₂O-2-C₆H₄SiMe₃ with Me₂NCHO using KF at 80°. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2SDS of cas: 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.SDS of cas: 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Preparation and characterization of novel organic/inorganic hybrid nanoparticles containing an organotin core and a polystyrene shell was written by Jia, Yong-Guang;Jiang, Jian;Liu, Ling-Yan;Chang, Wei-Xing;Li, Jing. And the article was included in Journal of Applied Polymer Science in 2012.HPLC of Formula: 27249-90-7 This article mentions the following:

A series of well-defined nanoparticles containing an organotin core and a polystyrene shell were obtained by crosslinking of n-Bu₂SnO with amphiphilic styrene-[6-(4-vinylphenoxy)hexanoic acid] diblock copolymers with various mol. weights The amphiphilic copolymers were synthesized via reversible addition fragmentation chain transfer polymerization and hydrolysis. The structures of the nanoparticles were studied by the transmission electron microscopy, SEM, and XPS anal. The morphol. of the crosslinked copolymer showed individual nanoparticles with regularly spherical shape. And the nanoparticle diameters decreased with increasing number of organotin carboxylate units. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7HPLC of Formula: 27249-90-7).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.HPLC of Formula: 27249-90-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Preparation of porous materials by amphiphilic block copolymer polystyrene-block-poly (vinyl pyrrolidone) self-assembly was written by Li, Ying;Han, Han;Yuan, Jinfang. And the article was included in Gongneng Cailiao in 2016.HPLC of Formula: 27249-90-7 This article mentions the following:

A series of diblock copolymers, polystyrene-block-poly (vinyl pyrrolidone) (PSt-b-PVP), with different hydrophilic/hydrophobic ratios was prepared by reversible addition fragmentation chain transfer (RAFT) polymerization The structures and properties of the diblock copolymers were characterized by FT IR, 1H NMR and GPC. Different additives and a series of PSt-b-PVP with different hydrophilic/hydrophobic ratios dissolved in selective solvents. After solvent evaporation, the transparent film was obtained by rising with water. FESEM was used to study the morphol. and size of the polymer porous material. The influence of additives, solvent evaporation temperature, the solvents and the hydrophilic/hydrophobic ratios on pore size were also studied. The results show that if the structure that we uses contains -OH functional groups or the monomer itself is used as additive, the porous polymer formed would have smaller holes. Meanwhile, reducing the heat is benefit to reduce the size of porous. And if we can use the structure which hydrophilic/hydrophobic ratios is PSt₁₀₁-b-PVP₇₉, it would be more easier to form smaller porous. Besides, using volatile solvent can be good for the forming of porous. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7HPLC of Formula: 27249-90-7).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.HPLC of Formula: 27249-90-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vanillin Alkanoates in the Synthesis of Hexahydrobenzacridine and Octahydroxanthene Derivatives was written by Kozlov, N. G.;Basalaeva, L. I.. And the article was included in Russian Journal of General Chemistry in 2005.COA of Formula: C12H14O4 This article mentions the following:

Cascade heterocyclization of 1,3-cyclohexanedione and dimedone with 2-naphthylamine and vanillin esters gave 2-methoxy-4-(alkyl-11-oxo-7,8,9,10,11,12-hexahydrobenz[a]acridin-12-yl)- and 2-methoxy-4-(alkyl-1,8-dioxo-2,3,4,5,6,7,8,9-octahydro-1H-xanthen-9-yl)phenyl esters of aliphatic (C₁-C₄) carboxylic acids. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4COA of Formula: C12H14O4).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. COA of Formula: C12H14O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

One-pot synthesis of 5-alkylthio-3H-1,2-dithiole-3-thiones: advantages and scopes was written by Aimar, Mario L.;De Rossi, Rita H.. And the article was included in Synthesis in 2000.Application of 1190-39-2 This article mentions the following:

The reaction of dialkyl malonate esters, ROCOCHR¹CO₂R [R = H, Me, Et, Pr, i-Pr, Ph, Bu, hexyl, octyl, decyl, benzyl, 2-ethoxyethyl, R¹ = H; R = Et, R¹ = Me, benzyl, Ph, Cl, OMe, Br, Br₂, NO₂], with P₂S₅/S₈ in boiling xylene in the presence of 2-mercaptobenzothiazole/ZnO as catalyst produced the corresponding 5-alkylthio-3H-1,2-dithiole-3-thiones I as major identifiable product. Moderate yields were obtained with malonate esters of primary alcs. The reaction failed with malonate esters of secondary alcs. Regarding the substituent in position two, dialkyl malonates with groups such as CH₃, Ph, CH₂Ph, OCH₃ and Cl afford the corresponding 4-substituted derivatives whereas with Br and NO₂ did not give the expected products. Some mechanistic evidences were described. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Application of 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of aromatic azomethines from anesthesin and derivatives of vanillin and vanillal was written by Dikusar, E. A.;Potkin, V. I.;Kozlov, N. G.;Yuvchenko, A. P.. And the article was included in Vestsi Natsyyanal’nai Akademii Navuk Belarusi, Seryya Khimichnykh Navuk in 2007.Formula: C12H14O4 This article mentions the following:

Novel aromatic azomethines 3-R¹O-4-R²OC₆H₃CH:NR³ (R¹ = Me, Et; R² = H, COMe, PhCH₂CO, BrCH₂CO, PhCO, etc.; R³ = 4-EtO₂CC₆H₄), containing ether and ester groups from vanillin, vanillal and their esters, were synthesized in 90-94% yields by condensation of the corresponding aldehydes 3-R¹O-4-R²OC₆H₃CHO with Et 4-aminobenzoate at reflux in absolute methanol in the absence of any catalyst. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4Formula: C12H14O4).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Formula: C12H14O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Small-Molecule TLR8 Antagonists via Structure-Based Rational Design was written by Hu, Zhenyi;Tanji, Hiromi;Jiang, Shuangshuang;Zhang, Shuting;Koo, Kyoin;Chan, Jean;Sakaniwa, Kentaro;Ohto, Umeharu;Candia, Albert;Shimizu, Toshiyuki;Yin, Hang. And the article was included in Cell Chemical Biology in 2018.Application of 525362-07-6 This article mentions the following:

Rational design of drug-like small-mol. ligands based on structural information of proteins remains a significant challenge in chem. biol. In particular, designs targeting protein-protein interfaces have met little success given the dynamic nature of the protein surfaces. Herein, we utilized the structure of a small-mol. ligand in complex with Toll-like receptor 8 (TLR8) as a model system due to TLR8′s clin. relevance. Overactivation of TLR8 has been suggested to play a prominent role in the pathogenesis of various autoimmune diseases; however, there are still few small-mol. antagonists available, and our rational designs led to the discovery of six exceptionally potent compounds with ~picomolar IC₅₀ values. Two X-ray crystallog. structures validated the contacts within the binding pocket. A variety of biol. evaluations in cultured cell lines, human peripheral blood mononuclear cells, and splenocytes from human TLR8-transgenic mice further demonstrated these TLR8 inhibitors′ high efficacy, suggesting strong therapeutic potential against autoimmune disorders. In the experiment, the researchers used many compounds, for example, Methyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 525362-07-6Application of 525362-07-6).

Methyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 525362-07-6) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application of 525362-07-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chemical constituents analysis in ground part of Gentiana macrophylla pall by SFE-GC-MS was written by Wang, Yanping;Ma, Xiao. And the article was included in Zhongguo Xiandai Yingyong Yaoxue in 2011.Computed Properties of C12H22O4 This article mentions the following:

The objective of this paper is to identify compounds in supercritical fluids extraction of ground part of Gentiana macrophylla Pall. GC-MS was used to analyze the constituents and the sample was extracted by supercritical fluids. The AT-SE54 capillary column (30 m × 0.25 mm × 0.25 μm) was used and inlet temperature was maintained at 260°. The column oven was begun at 80°, then programmed from 80° to 290° at 4° min^-1, and hold for 30 min. Helium at a constant flow rate of 1.2 mL/min^-1 was used as carrier gas. Ion source temperature was 230° and ionization energy was 70 eV. Results show that the total of 72 components were separated and 70 components were identified from flowers of Gentiana macrophylla Pall, accounting for 84.1% of total extractant. A total of 67 components were separated and 66 components were identified from stems and leaves of Gentiana macrophylla Pall, accounting for 93.1% of total extractant. It was concluded that the results will provide important foundation for understanding the constituents and further exploitation for ground part of Gentiana macrophylla Pall. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Computed Properties of C12H22O4).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Computed Properties of C12H22O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics