Tag: 200-300

Synthesis of α,ω-difunctional long-chain n-alkanes. I. Coupling of ω-functionalized acid chlorides by triethylamine was written by Zantour, Hedi;Pousse, Andre;Brini, Mathilde. And the article was included in Bulletin de la Societe Chimique de France in 1972.Application In Synthesis of 12-Methoxy-12-oxododecanoic acid This article mentions the following:

Ten difunctional ketones R (CH2)n-CO(CH2)nR (n = 6,8,10,15,16, 22 R = OMe, CN, Br, CH:CH2, C:O2H) are prepared by coupling of the corresponding R(CH2)n-COCl in the presence of Et3N. Β-Lactones (I) are intermediates which are isolated. In the experiment, the researchers used many compounds, for example, 12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0Application In Synthesis of 12-Methoxy-12-oxododecanoic acid).

12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application In Synthesis of 12-Methoxy-12-oxododecanoic acid

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vanillin and O-Ethyl Vanillin Esters in Reactions with 2-Naphthylamine and Cyclopentanone was written by Kozlov, N. G.;Dikusar, E. A.. And the article was included in Russian Journal of Organic Chemistry in 2019.Application of 20665-85-4 This article mentions the following:

The 4-(2,3-dihydro-1H-benzo[f]cyclopenta[c]quinolin-4-yl)-2-alkoxyphenyl esters of carboxylic acids I (R = CH₃, C₂H₅, CH(CH₃)₂; R¹ = CH₃, C₂H₅) have been synthesized by the three-component condensation of esters 4-RC(O)O-3-R¹OC₆H₃CHO derived from vanillin and O-Et vanillin with 2-naphthylamine and cyclopentanone in the presence of HCl as a catalyst. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4Application of 20665-85-4).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 20665-85-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Controlled radical copolymerization of N-vinylpyrrolidone and 1,1,1,3,3,3-hexafluoro isopropyl α-fluoroacrylate was written by Zaitsev, S. D.;Semchikov, Yu. D.;Chernikova, E. V.. And the article was included in Vysokomolekulyarnye Soedineniya, Seriya A i Seriya B in 2009.COA of Formula: C14H12S2 This article mentions the following:

Copolymers of N-vinylpyrrolidone and 1,1,1,3,3,3-hexafluoro iso-Pr α-fluoroacrylate with narrow mol. weight distribution were prepared in the presence of benzyl dithiobenzoate via pseudo-living radical polymerization with reversible chain transfer mechanism. Reactivities of the monomers were determined and alternating nature of the polymerization was confirmed. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7COA of Formula: C14H12S2).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.COA of Formula: C14H12S2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Etherlike compounds. XXVII. Turbid phases in compounds with reactivity minimums was written by Palomaa, Matti H.;Mikkila, Irma. And the article was included in Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen in 1942.SDS of cas: 1190-39-2 This article mentions the following:

In a study of the m.ps. and viscosities of esters of the oxalic acid series, it was observed that the esters of CH₂(CO₂H)₂ showed a region of turbidity before they solidified. The m.ps. and clearing points of the esters were: Me₂ -61.9°, -42.4°; Et₂ -48.9°, -40.3°; Pr₂ -77.1°, -62.9°; Bu₂ -95 ± 5°, -45.8°; Am₂ -54.9°, -34.0°. The dioctyl and di-iso-Pr esters melt clear at -6.3° and -50.7°. Esters of (CO₂H)₂, (CH₂CO₂H)₂ and (CH₂)₄(CO₂H)₂ do not show this behavior; m.ps. of the Me, Et, Pr, Bu and Am esters are given, together with reported values. The viscosity of CH₂(CO₂Me)₂ increased from 34.3 to 178.1 sec. in decreasing its temperature from 20° to -28.8° and from 225.9 to 1716.5 sec. in the range -34.90 to -57°. For the clear phase (20° to -31°) the viscosity of CH₂(CO₂Am)₂ increases from 17.9 to 154.6 sec.; for the turbid phase (-37° to -60°) the change is from 231 to 1896.8 sec. Data are given for the viscosities of (CO₂Am)₂, CH₂(CO₂Am)₂ and (CH₂CO₂Am)₂, using the same viscometer; the relative viscosity of the last ester is much greater than for the other two. The occurrence of the turbid phase is believed to be the result of a decreased cohesive power because of intermol. or intramol. saturation In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2SDS of cas: 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.SDS of cas: 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chiral Iridium Catalysts Bearing Spiro Pyridine-Aminophosphine Ligands Enable Highly Efficient Asymmetric Hydrogenation of β-Aryl β-Ketoesters was written by Xie, Jian-Hua;Liu, Xiao-Yan;Yang, Xiao-Hui;Xie, Jian-Bo;Wang, Li-Xin;Zhou, Qi-Lin. And the article was included in Angewandte Chemie, International Edition in 2012.Synthetic Route of C12H14O3 This article mentions the following:

A highly efficient asym. hydrogenation of β-dicarbonyl compounds, including β-ketoesters, β-ketoamides and β-diketones, catalyzed by iridium complexes with SpiroPAP (spiro pyridine-aminophosphine) ligands is reported. The reaction provides β-hydroxy esters/amides and diols in excellent enantioselectivity (up to 99.8% ee) and extremely high TONs (up to 1230000), which represents the highest level of efficiency in the asym. hydrogenation of β-ketoesters. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Synthetic Route of C12H14O3).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C12H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pyrene-Based Porous Organic Polymers as Efficient Catalytic Support for the Synthesis of Biodiesels at Room Temperature was written by Kundu, Sudipta K.;Bhaumik, Asim. And the article was included in ACS Sustainable Chemistry & Engineering in 2015.Related Products of 106-79-6 This article mentions the following:

New pyrene-based microporous organic polymers PPOP-1, PPOP-2, and PPOP-3 have been synthesized via Friedel-Crafts alkylation reaction between pyrene and bis(1,4-dibromomethyl)benzene at their different molar ratios in the presence of a Lewis acid catalyst FeCl₃ under refluxing conditions. Pore surfaces of PPOP-1, PPOP-2, and PPOP-3 have been functionalized by -SO₃H groups via chlorosulfonic acid treatment under controlled reaction conditions to obtain sulfonated porous organic polymers, and these are designated as SPPOP-1, SPPOP-2, and SPPOP-3, resp. Powder X-ray diffraction, N₂ sorption, HR-TEM, FE-SEM, NH₃-TPD, solid state ¹³C CP MAS-NMR, and FT-IR spectroscopic tools are employed to characterize these materials. These sulfonated porous polymers showed nanofiber-like or spherical morphol., very high surface acidity, and excellent catalytic activity for the synthesis of biodiesels via esterification/transesterification of long chain fatty acids/esters at room temperature together with very high recycling efficiency, suggesting the future potential of these sulfonated porous polymers in a wide range of sustainable acid-catalyzed chem. reactions. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Related Products of 106-79-6).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 106-79-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A new small molecule gelator and 3D framework ligator of lead(II) was written by Knichal, Jane V.;Gee, William J.;Burrows, Andrew D.;Raithby, Paul R.;Wilson, Chick C.. And the article was included in CrystEngComm in 2015.Reference of 313648-56-5 This article mentions the following:

Reacting equimolar quantities of 5-allenyl-1,3-benzenedicarboxylic acid (H₂abd) with lead(II) acetate trihydrate in N,N-dimethylformamide (DMF) under solvothermal conditions gave a metallogel with a critical gelation percentage of 1% weight/volume Elemental anal. performed on the gel provided a mol. composition ratio of [Pb(abd)(H₂O)]_n (1). Viewing the gel by SEM identified an entangled network of crosslinked nano-fibers. ¹H-NMR aliquots of hydrated lead(II) acetate added to a solution of H₂abd in deuterated DMF allows inferences to be made about solution-state behavior that occurs during the initial gel aggregation stage. Under non-solvothermal conditions, combining H₂abd and hydrated lead(II) acetate gave single crystals suitable for x-ray diffraction, which were identified as a 3D coordination polymer with composition [Pb(abd)(DMF)] (2). Structural features observed within this 3D coordination polymer provide the basis for assigning the mol. structure to the fibrils present within gel 1. This assertion is supported by comparable vibrational profiles taken from a sample of dried gel 1 to that of crystalline 2, and the matching of early solution-state ¹H-NMR spectroscopic trends to later solid-state observations. In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Reference of 313648-56-5).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Reference of 313648-56-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cu-Catalyzed Aminodifluoroalkylation of Alkynes and α-Bromodifluoroacetamides was written by Lv, Yunhe;Pu, Weiya;Chen, Qian;Wang, Qingqing;Niu, Jiejie;Zhang, Qian. And the article was included in Journal of Organic Chemistry in 2017.Application of 185619-66-3 This article mentions the following:

The copper-catalyzed highly regioselective aminodifluoroalkylation of alkynes and α-bromodifluoroacetamides was realized for the first time. With this method, 3,3-difluoro-1H-pyrrol-2(3H)-ones were constructed in a single step from various alkynes and α-bromodifluoroacetamides substrates without using any extra oxidant. In the experiment, the researchers used many compounds, for example, tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3Application of 185619-66-3).

tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 185619-66-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Two Functional Porous Metal-Organic Frameworks Constructed from Expanded Tetracarboxylates for Gas Adsorption and Organosulfurs Removal was written by Luo, Xiaolong;Kan, Liang;Li, Xiang;Sun, Libo;Li, Guanghua;Zhao, Jun;Li, Dong-Sheng;Huo, Qisheng;Liu, Yunling. And the article was included in Crystal Growth & Design in 2016.Recommanded Product: Dimethyl 5-ethynylisophthalate This article mentions the following:

Two fof-type porous metal-organic frameworks (MOFs), [Cu₂(bdfdpa)(H₂O)₂]·8DMF·2H₂O (JLU-Liu29) and [Cu₂(btadpa)(H₂O)₂]·7DMF·8H₂O (JLU-Liu30) (H₄bdfdpa = 5,5′-(benzo[1,2-b:4,5-b’]difuran-2,6-diyl)diisophthalic acid and H₄btadpa = 5,5′-(benzo[c][1,2,5]thiadiazole-4,7-diylbis(ethyne-2,1-diyl))diisophthalic acid), have been successfully synthesized by using different expanded tetracarboxylate ligands. Both of them exhibit good permanent porosity and high surface areas of 2205 and 1791 m²g^-1, resp. Due to open metal sites, different functional groups, and suitable pore spaces, the two porous MOFs exhibit high adsorption performance for small mol. gases (CO₂, CH₄, C₂H₆, and C₃H₈) and removal of refractory organosulfur compounds In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Recommanded Product: Dimethyl 5-ethynylisophthalate).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: Dimethyl 5-ethynylisophthalate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lipase-catalyzed synthesis of polymeric prodrugs of nonsteroidal anti-inflammatory drugs was written by Qian, Xueqi;Wu, Qi;Xu, Fangli;Lin, Xianfu. And the article was included in Journal of Applied Polymer Science in 2013.Formula: C12H22O4 This article mentions the following:

Because of the potential application of prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs), Candida antarctica lipase B (CAL-B) catalyzed polycondensation of profen-containing diol monomers and diesters were designed to prepare a series of biodegradable polymeric prodrugs composed of NSAID branches and poly(amide-co-ester) backbone. The structure of the products was confirmed by Fourier transform IR spectroscopy, NMR, and gel permeation chromatog. (GPC). The reaction conditions of polymerization, such as the enzyme source, amount of catalyst, and temperature, were optimized. The mol. weights of resultant copolymers were 2170-13,270 g/mol, with corresponding polydispersities from 1.17 to 2.4. The copolymers had relatively high drug loadings of 44.7-59.7 wt % because every repeat unit contained one drug mol. The strategy of enzymic polymerization appeared to be quite general and accommodated a large number of comonomer substrates with various chain lengths and substituents. The optically pure (R)-naproxen monomer was demonstratively incorporated into the corresponding copolymers with the developed synthesis strategy. The in vitro study showed that the polyester could release the drug effectively under physiol. conditions with enzyme, which indicated that the obtained product could be a promising prodrug for extending pharmacol. effects by delayed drug release. With GPC anal., we confirmed that the prodrug was completely degradable in aqueous solution The attractive features of the copolymer were its high drug loading, biodegradability, and biocompatibility. The high tolerance of the CAL-B toward drug groups, as described in this article, provides a new route for synthesizing polymeric drugs with potential biomedical applications in mild conditions and for reducing environmental impact. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2012. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Formula: C12H22O4).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Formula: C12H22O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics