Tag: 200-300

Bronsted acid catalyzed amination of 1,3-dicarbonyl compounds by iminoiodanes was written by Tejo, Ciputra;Yeo, Hui Quan;Chan, Philip Wai Hong. And the article was included in Synlett in 2014.Safety of Ethyl 3-oxo-3-(m-tolyl)propanoate This article mentions the following:

A synthetic method to aminate 1,3-dicarbonyl compounds with PhI:NTs using Bronsted acid catalysis is described herein. The method was shown to be applicable to β-keto esters and phosphonates as well as 1,3-diones, providing the corresponding α,α-acyl amino acid derivatives in moderate to excellent yields. E.g., amination of PhCOCH₂CO₂Et with PhI:NTs in the presence of 10 mol% of TFA and 4 Å MS in dichloromethane at 0 °C for 90 min gave 85% aminated product I. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Safety of Ethyl 3-oxo-3-(m-tolyl)propanoate).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Safety of Ethyl 3-oxo-3-(m-tolyl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Organic-inorganic hybrid catalysts based on ordered porous structures for Michael reaction was written by Kubota, Yoshihiro;Ikeya, Hisanori;Sugi, Yoshihiro;Yamada, Takashi;Tatsumi, Takashi. And the article was included in Journal of Molecular Catalysis A: Chemical in 2006.Product Details of 1190-39-2 This article mentions the following:

Two types of organic-inorganic hybrid base catalysts are prepared for the Michael reaction. Organic-functionalized mol. sieves (OFMSs), particularly “amine-immobilized porous silicates”, are designed based on a common idea of immobilizing active catalytic sites on silicate surface. Silicate-organic composite materials (SOCMs), such as “ordered porous silicate-quaternary ammonium composite materials”, are the precursors of ordered porous silicates obtained during the synthesis. The OFMSs are effective when the supports have large pore volume and/or surface area and the reaction is carried out in polar solvents ethanol and DMF. However, the activity of the OFMSs is considerably low in a non-polar solvent such as benzene. In contrast, the SOCMs are remarkably active in benzene. The organic cation-MCM-41 composite is more active than the composite of an organic cation and a microporous silicate such as zeolite beta and ZSM-12. In the SOCM catalysts, (SiO)₃SiO^–(⁺NR₄) moieties located at the accessible sites are considered to play some important roles. The active species are absent in the liquid phase after the reaction. The recycle of the catalyst was possible without significant loss of activity when the substrates are enough reactive. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Product Details of 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Product Details of 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jack Chambers’ mixed media paintings from the 1960s and 1970s: Painting technique and condition was written by Helwig, Kate;Thibeault, Marie-Eve;Poulin, Jennifer. And the article was included in Studies in Conservation in 2013.Application of 106-79-6 This article mentions the following:

This study describes the examination and anal. of four mixed media paintings from the 1960s and 1970s by Canadian artist Jack Chambers (1931-1978). The documentary evidence about his materials and methods is summarized and compared with the results of anal. of multilayer paint samples. The combination of Fourier transform IR spectroscopy (FTIR) and gas chromatog.-mass spectrometry (GC-MS) allowed the components of the paint media to be characterized: ortho-phthalate alkyd resins, iso-phthalate alkyd resins, drying oils, dammar, Pinaceae resin, and turpentine were identified in varying proportions. Many pigments and fillers were identified by FTIR and Raman and are enumerated. The effect that Chambers’ complex technique has had on the aging and degradation of the paintings is discussed. The severe cracking of the paint layers in one of the four paintings may be the result of a high proportion of dammar and turpentine diluent mixed with the alkyd paint and may also be related to the type of alkyd resin medium. Different history and environmental conditions may also be factors. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Application of 106-79-6).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 106-79-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin was written by Cominetti, Marco M. D.;Goffin, Sarah A.;Raffel, Ewan;Turner, Kerrie D.;Ramoutar, Jordann C.;O’Connell, Maria A.;Howell, Lesley A.;Searcey, Mark. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2015.Related Products of 313648-56-5 This article mentions the following:

Previous studies on the natural product chlorofusin have shown that the full peptide and azaphilone structure are required for inhibition of the interaction between MDM2 and p53. In the current work, the authors utilized the cyclic peptide as a template and introduced an azidonorvaline amino acid in place of the ornithine/azaphilone of the natural product and carried out click chem. with the resulting peptide. From this small library the first ever non-azaphilone containing chlorofusin analog with MDM2/p53 activity was identified. Further studies then suggested that the simple structure of the Fmoc-norvaline amino acid that had undergone a click reaction was also able to inhibit MDM2/p53 interaction. This is an example where studies of a natural product have led to the serendipitous identification of a new small mol. inhibitor of a protein-protein interaction. In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Related Products of 313648-56-5).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Related Products of 313648-56-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of α,ω-difunctional long-chain n-alkanes. I. Coupling of ω-functionalized acid chlorides by triethylamine was written by Zantour, Hedi;Pousse, Andre;Brini, Mathilde. And the article was included in Bulletin de la Societe Chimique de France in 1972.Application In Synthesis of 12-Methoxy-12-oxododecanoic acid This article mentions the following:

Ten difunctional ketones R (CH2)n-CO(CH2)nR (n = 6,8,10,15,16, 22 R = OMe, CN, Br, CH:CH2, C:O2H) are prepared by coupling of the corresponding R(CH2)n-COCl in the presence of Et3N. Β-Lactones (I) are intermediates which are isolated. In the experiment, the researchers used many compounds, for example, 12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0Application In Synthesis of 12-Methoxy-12-oxododecanoic acid).

12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application In Synthesis of 12-Methoxy-12-oxododecanoic acid

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vanillin and O-Ethyl Vanillin Esters in Reactions with 2-Naphthylamine and Cyclopentanone was written by Kozlov, N. G.;Dikusar, E. A.. And the article was included in Russian Journal of Organic Chemistry in 2019.Application of 20665-85-4 This article mentions the following:

The 4-(2,3-dihydro-1H-benzo[f]cyclopenta[c]quinolin-4-yl)-2-alkoxyphenyl esters of carboxylic acids I (R = CH₃, C₂H₅, CH(CH₃)₂; R¹ = CH₃, C₂H₅) have been synthesized by the three-component condensation of esters 4-RC(O)O-3-R¹OC₆H₃CHO derived from vanillin and O-Et vanillin with 2-naphthylamine and cyclopentanone in the presence of HCl as a catalyst. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4Application of 20665-85-4).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 20665-85-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Controlled radical copolymerization of N-vinylpyrrolidone and 1,1,1,3,3,3-hexafluoro isopropyl α-fluoroacrylate was written by Zaitsev, S. D.;Semchikov, Yu. D.;Chernikova, E. V.. And the article was included in Vysokomolekulyarnye Soedineniya, Seriya A i Seriya B in 2009.COA of Formula: C14H12S2 This article mentions the following:

Copolymers of N-vinylpyrrolidone and 1,1,1,3,3,3-hexafluoro iso-Pr α-fluoroacrylate with narrow mol. weight distribution were prepared in the presence of benzyl dithiobenzoate via pseudo-living radical polymerization with reversible chain transfer mechanism. Reactivities of the monomers were determined and alternating nature of the polymerization was confirmed. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7COA of Formula: C14H12S2).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.COA of Formula: C14H12S2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Etherlike compounds. XXVII. Turbid phases in compounds with reactivity minimums was written by Palomaa, Matti H.;Mikkila, Irma. And the article was included in Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen in 1942.SDS of cas: 1190-39-2 This article mentions the following:

In a study of the m.ps. and viscosities of esters of the oxalic acid series, it was observed that the esters of CH₂(CO₂H)₂ showed a region of turbidity before they solidified. The m.ps. and clearing points of the esters were: Me₂ -61.9°, -42.4°; Et₂ -48.9°, -40.3°; Pr₂ -77.1°, -62.9°; Bu₂ -95 ± 5°, -45.8°; Am₂ -54.9°, -34.0°. The dioctyl and di-iso-Pr esters melt clear at -6.3° and -50.7°. Esters of (CO₂H)₂, (CH₂CO₂H)₂ and (CH₂)₄(CO₂H)₂ do not show this behavior; m.ps. of the Me, Et, Pr, Bu and Am esters are given, together with reported values. The viscosity of CH₂(CO₂Me)₂ increased from 34.3 to 178.1 sec. in decreasing its temperature from 20° to -28.8° and from 225.9 to 1716.5 sec. in the range -34.90 to -57°. For the clear phase (20° to -31°) the viscosity of CH₂(CO₂Am)₂ increases from 17.9 to 154.6 sec.; for the turbid phase (-37° to -60°) the change is from 231 to 1896.8 sec. Data are given for the viscosities of (CO₂Am)₂, CH₂(CO₂Am)₂ and (CH₂CO₂Am)₂, using the same viscometer; the relative viscosity of the last ester is much greater than for the other two. The occurrence of the turbid phase is believed to be the result of a decreased cohesive power because of intermol. or intramol. saturation In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2SDS of cas: 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.SDS of cas: 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chiral Iridium Catalysts Bearing Spiro Pyridine-Aminophosphine Ligands Enable Highly Efficient Asymmetric Hydrogenation of β-Aryl β-Ketoesters was written by Xie, Jian-Hua;Liu, Xiao-Yan;Yang, Xiao-Hui;Xie, Jian-Bo;Wang, Li-Xin;Zhou, Qi-Lin. And the article was included in Angewandte Chemie, International Edition in 2012.Synthetic Route of C12H14O3 This article mentions the following:

A highly efficient asym. hydrogenation of β-dicarbonyl compounds, including β-ketoesters, β-ketoamides and β-diketones, catalyzed by iridium complexes with SpiroPAP (spiro pyridine-aminophosphine) ligands is reported. The reaction provides β-hydroxy esters/amides and diols in excellent enantioselectivity (up to 99.8% ee) and extremely high TONs (up to 1230000), which represents the highest level of efficiency in the asym. hydrogenation of β-ketoesters. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Synthetic Route of C12H14O3).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C12H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pyrene-Based Porous Organic Polymers as Efficient Catalytic Support for the Synthesis of Biodiesels at Room Temperature was written by Kundu, Sudipta K.;Bhaumik, Asim. And the article was included in ACS Sustainable Chemistry & Engineering in 2015.Related Products of 106-79-6 This article mentions the following:

New pyrene-based microporous organic polymers PPOP-1, PPOP-2, and PPOP-3 have been synthesized via Friedel-Crafts alkylation reaction between pyrene and bis(1,4-dibromomethyl)benzene at their different molar ratios in the presence of a Lewis acid catalyst FeCl₃ under refluxing conditions. Pore surfaces of PPOP-1, PPOP-2, and PPOP-3 have been functionalized by -SO₃H groups via chlorosulfonic acid treatment under controlled reaction conditions to obtain sulfonated porous organic polymers, and these are designated as SPPOP-1, SPPOP-2, and SPPOP-3, resp. Powder X-ray diffraction, N₂ sorption, HR-TEM, FE-SEM, NH₃-TPD, solid state ¹³C CP MAS-NMR, and FT-IR spectroscopic tools are employed to characterize these materials. These sulfonated porous polymers showed nanofiber-like or spherical morphol., very high surface acidity, and excellent catalytic activity for the synthesis of biodiesels via esterification/transesterification of long chain fatty acids/esters at room temperature together with very high recycling efficiency, suggesting the future potential of these sulfonated porous polymers in a wide range of sustainable acid-catalyzed chem. reactions. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Related Products of 106-79-6).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 106-79-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics