Tag: 200-300

Romero, Eugenie; Minard, Corinne; Benchekroun, Mohamed; Ventre, Sandrine; Retailleau, Pascal; Dodd, Robert H.; Cariou, Kevin published an article in 2017, the title of the article was Base-Mediated Generation of Ketenimines from Ynamides: Direct Access to Azetidinimines by an Imino-Staudinger Synthesis.Formula: C12H14F3NO2 And the article contains the following content:

Ynamides were used as precursors for the in situ generation of highly reactive ketenimines that could be trapped with imines in a [2+2] cycloaddition This imino-Staudinger synthesis led to a variety of imino-analogs of β-lactams, namely azetidinimines I [Ar1 = Ph, 4-MeOC6H4, 4-ClC6H4, 4-BrC6H4, 4-IC6H4, 4-F3CC6H4; Ar2 = Ph, 4-MeOC6H4, 4-ClC6H4, 4-BrC6H4, 4-IC6H4, 4-MeO2CC6H4, 4-t-Bu-O2CC6H4; Ar3 = Ph, 4-MeOC6H4] that could be further functionalized through a broad range of transformations. The experimental process involved the reaction of tert-Butyl (4-(trifluoromethyl)phenyl)carbamate(cas: 141940-37-6).Formula: C12H14F3NO2

The Article related to azetidinimine preparation, ketenimine insitu generation ynamide imine imino staudinger cycloaddition, staudinger synthesis, [2+2] cycloaddition, azetidinimines, ketenimines, ynamides and other aspects.Formula: C12H14F3NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 7, 2021, Chen, Peiran; Dai, Xueqi published an article.Reference of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate The title of the article was Site-specific synthesis of 3-Se-1,2-unsaturated glycosides with R-Se-Se-R as the nucleophile precursors promoted by InCl3/Hf(OTf)4. And the article contained the following:

By using Hf(OTf)4 as the catalyst, a series of 3-Se 1,2-unsaturated glucosides, e.g. I, have been synthesized site-specifically from tri-O-acetyl-D-glucal, 3,4-di-O-acetyl-L-rhamnal or 2,4,6-tri-O-benzyl-D-glucal with alkyl(aryl) hydroselenides as the nucleophile precursors in good yield. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Reference of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

The Article related to substitution catalyst selenoglycoside preparation hafnium triflate indium chloride catalyst, selenoglycoside preparation hafnium triflate indium chloride catalyst selenylation glycal and other aspects.Reference of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On November 30, 1981, Fujisawa, Seiichiro; Masuhara, Eiichi published an article.Quality Control of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate) The title of the article was Determination of partition coefficients of acrylates, methacrylates, and vinyl monomers using high performance liquid chromatography (HPLC). And the article contained the following:

Retention times (Rt) for acrylates, methacrylates, and vinyl monomers were measured with 2 different columns (C18 Corasil and C8 LiChrosorb) using reverse-phase HPLC in order to obtain their partition coefficients between 1-octanol and water (log P). The log P values of test compounds were determined from the regression curves between Rt and log P values of a number of standards using C8 LiChrosorb. The log P values obtained in this manner agreed closely with the log P values observed in previous studies. However, the peaks of these compounds were not sharp and some compounds were eluted for > 10 min. Thus, the measurement of accurate Rt values is tedious. C18 Corasil was therefore used in a mobile phase (MeOH-H2O 85:15). The Rt of some methacrylates with P values over 4 were delayed due to the hydrophobic interaction between these compounds and the C18 packing material. However, in the measurable region of the log P values (about -1 to +4), log P correlated linearly with log Rt following 2 different regression curves: one for aliphatic and aromatic compounds with the functional groups (r = 0.92), and the other for compounds without these groups (r = 0.99). Log P values of methacrylates widely used in dentistry can be determined easily and accurately by HPLC. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Quality Control of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

The Article related to partition coefficient acrylate monomer, liquid chromatog acrylate monomer, methacrylate monomer liquid chromatog, vinyl monomer liquid chromatog, dental monomer partition coefficient and other aspects.Quality Control of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Schank, Kurt published an article in 1970, the title of the article was Base catalyzed rearrangement of α-acetoxy-β-oxosulfones. Signs for the intermediate existence of valence tautomeric α-acetoxyketenes.Category: esters-buliding-blocks And the article contains the following content:

Deprotonation of RCOCH(OAc)SO2R1 with tertiary bases leads to the formation of the shortlived intermediates RCOC-(OAc)SO2R1 ⇌ RC(O-):C(OAc)SO2R1 (I), which were trapped by azo coupling with p-N2+C6H4Cl to give RCO(AcO)C(SO2R1)N:NC6H4Cl-p (where R = Ph, C6H4CH:CH, p-MeOC6H4, or p-O2NC6H4 and R1 = Ph or p-MeC6H4). In inert solvents the tautomeric anions I undergo a fast acyl migration followed by elimination of RSO2-. The formation of the very reactive R(AcO)C:CO (II) is assumed, which can react with RSO2- in a known manner at the O atom or, depending on the p-substituents in II, can lead to the formation of p-O2NC6H4CH(OAc)SO2R (where R = Ph or p-MeC6H4) via valence tautomers of II. The experimental process involved the reaction of tert-Butyl 2-(4-nitrophenyl)acetate(cas: 29704-38-9).Category: esters-buliding-blocks

The Article related to acetoxy oxo sulfones rearrangement mechanism, oxo acetoxy sulfones rearrangement mechanism, sulfones acetoxy oxo rearrangement mechanism, rearrangement mechanism acetoxy oxo sulfones and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kumar, Harikesh; Dubey, Atul; Prajapati, Gurudayal; Kant, Ruchir; Ampapathi, Ravi S.; Mandal, Pintu Kumar published an article in 2022, the title of the article was Regioselective direct sulfenylation of glycals using arylsulfonyl chlorides in the presence of triphenylphosphine: access to C2-thioaryl glycosides.Recommanded Product: (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate And the article contains the following content:

Direct triphenylphosphine-mediated regioselective sulfenylation of glycals by using various cheap and easily available aryl sulfonyl chlorides as a sulfur source to generate different C2-S-aryl-glycosides was developed. Notably, the features of this protocol offer a milder and easier operational procedure, and broad substrate scope with complete regioselectivity at C-2. Experiments and DFT calculations supported the proposed mechanism and regioselectivity for the formation of C2-S-aryl-glycosides. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Recommanded Product: (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

The Article related to regioselective sulfenylation glycal arylsulfonyl chloride phenylphosphine aryl thioglycoside, crystal structure transition state glycal monosaccharide preparation thioaryl glycoside and other aspects.Recommanded Product: (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Abe, Haruka published an article in 2021, the title of the article was National standard and new reference material for specific heat capacity measurements.Category: esters-buliding-blocks And the article contains the following content:

Thermal anal. and calorimetry share a close relationship in the field of thermal research. With regards to the sp. heat capacity, researchers have been able to realize absolute measurement techniques by utilizing drop, conduction, and adiabatic methods that are used in calorimetry. Furthermore, it is possible to optimize differential scanning calorimetry, which is a comparative measurement technique for the sp. heat capacity used in thermal anal., by improving the absolute measurement techniques. At the National Metrol. Institute of Japan (NMIJ), we developed a new certified reference material (CRM) for comparatively measuring the sp. heat capacity, the single-crystalline silicon-NMIJ CRM 5806a, using a new type of cryogenic adiabatic calorimeter equipped with a pulse-tube refrigerator working at from 50 to 350 K. This CRM was produced in accordance with the quality specifications of NMIJ, and complies with the ISO/IEC 17025, ISO 17034, and ISO GUIDE 35 standards This paper reports on the procedure for fabricating this CRM and using it to perform sp. heat capacity measurements at low temperatures The sp. heat capacity was measured using a differential scanning calorimeter at from 280 to 340 K. NMIJ CRM 5806a was used to calibrate the heat flow. It was found that the uncertainty evaluation became easier because one factor of the uncertainty evaluation could be removed using the CRM. We show that the development of the CRM using the adiabatic calorimeter has led to an improvement in the sp. heat capacity measurement results obtained by the differential scanning calorimeter. The experimental process involved the reaction of Phenyl Salicylate(cas: 118-55-8).Category: esters-buliding-blocks

The Article related to specific heat capacity standard reference material, specific heat capacity, adiabatic calorimeter, differential scanning calorimeter, reference material, single-crystalline silicon and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mleziva, Josef; Jarusek, Jaroslav; Cermak, Vladimir; Vecera, Miroslav published an article in 1978, the title of the article was Epoxy-acrylic esters as film-formers for uv curing.Related Products of 1985-51-9 And the article contains the following content:

The effectiveness of various catalysts (quaternary ammonium salts, amines) in the esterification of bisphenol A- epichlorohydrin copolymer [25068-38-6] by methacrylic acid [79-41-4] is discussed. The effect of polyol acrylates and methacrylates on the viscosity of epoxy methacrylates and on the photochem. reactivity of coatings is described. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Related Products of 1985-51-9

The Article related to methacrylic acid esterification epoxy resin, catalyst esterification epoxy resin, epoxy resin acrylate coating, crosslinking photochem epoxy acrylate, amine catalyst esterification epoxy and other aspects.Related Products of 1985-51-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On May 10, 2020, Zhang, Kaige; Li, Shuangying; Wang, Yunhe; Fan, Jing; Zhu, Guifen published an article.Synthetic Route of 118-55-8 The title of the article was Air-assisted liquid-liquid microextraction based on solidification of floating deep eutectic solvent for the analysis of ultraviolet filters in water samples by high performance liquid chromatography with the aid of response surface methodology. And the article contained the following:

For this work, a novel air-assisted liquid-liquid microextraction based on solidification of floating deep eutectic solvent (AA-LLME-SFDES), coupled with a high performance liquid chromatog. (HPLC) method was developed for the detection of benzophenone and salicylate UV filters in water samples. Three types of fatty acid-based hydrophobic deep eutectic solvents (DESs) with low viscosity, low-d., and m.p. close to room temperature were prepared and employed as extraction solvents. This air-assisted liquid-liquid microextraction was carried out in a glass centrifuge tube. Subsequently, the glass tube was introduced into ice-water bath and held for 3 min, during which the upper DES phase was solidified. The water phase was easily extracted using a syringe equipped with a long needle, and later, the glass tube was removed from ice-water bath. The solidified DES phase was immediately melted at room temperature and used for HPLC anal. The response surface methodol. was employed to optimize some influencing parameters such as the volume of the extraction solvent, the pH value of sample solution, the number of extraction cycles, and the addition of salt. A quadratic model, namely a central composite design, was used to replace the conventional single factor anal. It was found that under optimal conditions, the limits of determination and quantification were 0.045-0.54μg L-1 and 0.15-2.0μg L-1, resp. The relative standard deviations for inter-day (n = 5) and intra-day (n = 5) precision were ≤ 4.2%, whereas the enrichment factors for the UV filters were obtained from 41 to 50. Furthermore, this novel method was successfully employed for the detection of benzophenone and salicylate UV filters from real water samples. The recoveries ranged from 87.5% to 105.8%, whereas the RSDs were lower than 3.6%. The experimental process involved the reaction of Phenyl Salicylate(cas: 118-55-8).Synthetic Route of 118-55-8

The Article related to air assisted microextraction deep eutectic uv filter water analysis, air-assisted liquid-liquid microextraction, deep eutectic solvent, response surface methodology, ultraviolet filters and other aspects.Synthetic Route of 118-55-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On February 25, 2022, Addanki, Rupa Bai; Halder, Suvendu; Kancharla, Pavan K. published an article.SDS of cas: 2873-29-2 The title of the article was TfO-···H-O-H Interaction-Assisted Generation of a Silicon Cation from Allylsilanes: Access to Phenylallyl Ferrier Glycosides from Glycals. And the article contained the following:

We demonstrate here that the strained and bulky protonated 2,4,6-tri-tert-butylpyridine (TTBPy) triflate salt serves as a mild and efficient organocatalyst for the diastereoselective C-Ferrier glycosylation of various glycals. The criticality of the role of 1/2 H2O mol. trapped in the catalyst has been disclosed. The mechanism of action involves unique anionic triflate and H2O hydrogen bond interactions assisting the activation of allylsilanes that provides unprecedented access to diastereoselective phenylallyl Ferrier glycosides. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).SDS of cas: 2873-29-2

The Article related to organocatalyst diastereoselective ferrier glycosylation glycal allylsilane hydrogen bond, crystal structure diastereoselective phenylallyl ferrier glycoside allylsilane silicon cation and other aspects.SDS of cas: 2873-29-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 30, 2020, Hasan Ali, Omar; Bomze, David; Ring, Sandra S.; Berner, Fiamma; Fassler, Mirjam; Diem, Stefan; Abdou, Marie-Therese; Hammers, Christoph; Emtenani, Shirin; Braun, Anne; Cozzio, Antonio; Mani, Bernhard; Jochum, Wolfram; Schmidt, Enno; Zillikens, Detlef; Sadik, Christian D.; Flatz, Lukas published an article.Application of 2358-84-1 The title of the article was BP180-specific IgG is associated with skin adverse events, therapy response, and overall survival in non-small cell lung cancer patients treated with checkpoint inhibitors. And the article contained the following:

Anti-programmed cell death protein 1 (PD1)/programmed death-ligand 1(PD-L1) therapy frequently entails immune-related adverse events (irAEs), and biomarkers to predict irAEs are lacking. Although checkpoint inhibitors have been found to reinvigorate T cells, the relevance of autoantibodies remains elusive. Our aim was to explore whether IgG autoantibodies directed against coexpressed antigens by tumor tissue and healthy skin correlate with skin irAEs and therapy outcome. We measured skin-specific IgG via ELISA in patients with non-small cell lung cancer (NSCLC) who received anti-PD1/PD-L1 treatment between July 2015 and Sept. 2017 at the Kantonsspital St. Gallen. Sera were sampled at baseline and during therapy after 8 wk. Anal. of publicly available tumor expression data revealed that NSCLC and skin coexpress BP180, BP230, and type VII collagen. A skin irAE developed in 16 of 40 recruited patients (40%). Only elevated anti-BP180 IgG at baseline significantly correlated with the development of skin irAEs (P = .04), therapy response (P = .01), and overall survival (P = .04). The patients were recruited in a single tertiary care center. Our data suggest that the level of anti-BP180 IgG of NSCLC patients at baseline is associated with better therapy response and overall survival and with a higher probability to develop skin irAEs during anti-PD1/PD-L1 treatment. The experimental process involved the reaction of Oxybis(ethane-2,1-diyl) bis(2-methylacrylate)(cas: 2358-84-1).Application of 2358-84-1

The Article related to bp180 igg checkpoint inhibitor nonsmall cell lung cancer, anti-pd1, autoantibodies, immune checkpoint inhibitors, immune-related adverse events, non-small cell lung cancer, skin rash and other aspects.Application of 2358-84-1

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics