Tag: 200-300

On February 5, 1986, Iwasaki, Genji; Saeki, Seitaro; Hamana, Masatomo published an article.Quality Control of tert-Butyl 2-(4-nitrophenyl)acetate The title of the article was A novel nucleophilic substitution of the formyl group in p-nitrobenzaldehyde with some carbanions. And the article contained the following:

p-O2NC6H4CHO (I) reacted with some active methylene compounds in the presence of a strong base at low temperatures to give p-substituted nitrobenzenes by a 2-step course involving the initial formation of the aldol adducts and the subsequent displacement of the carbinol moieties with excess carbanions. p-O2NC6H4CHROH were formed preferentially from RH (R = CHMeCOPh, CHMeCOEt, CH2CO2CMe3) or exclusively from RH [R = CMe2, COCHMe2, CH(CN)2]. Thus, I was added to MeCOPr in Me3COK in liquid NH3 at -70° to give 85% p-O2NC6H4CH2COPr. The experimental process involved the reaction of tert-Butyl 2-(4-nitrophenyl)acetate(cas: 29704-38-9).Quality Control of tert-Butyl 2-(4-nitrophenyl)acetate

The Article related to nucleophile substitution nitrobenzaldehyde carbanion, formyl group substitution carbanion, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Aldehydes and Derivatives, Including Sulfur Analogs and other aspects.Quality Control of tert-Butyl 2-(4-nitrophenyl)acetate

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Ester – Wikipedia,
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On August 13, 2013, Lattuada, Marco; Del Gado, Emanuela; Abete, Tiziana; de Arcangelis, Lucilla; Lazzari, Stefano; Diederich, Vincent; Storti, Giuseppe; Morbidelli, Massimo published an article.Recommanded Product: 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate) The title of the article was Kinetics of Free-Radical Cross-Linking Polymerization: Comparative Experimental and Numerical Study. And the article contained the following:

Modeling free radical polymerization processes in the presence of crosslinkers is a challenging problem that has been addressed using numerous techniques for over more than half a century. However, a model providing a comprehensive description of the phenomenon has not been proposed yet. In this work, we implement a simple free-radical polymerization scheme of a monovinyl (difunctional) monomer and a divinyl (tetrafunctional) crosslinker in a Monte Carlo (MC) scheme, which describes polymer dynamics using a bond-fluctuation model. MC simulations allow us to follow the entire polymerization kinetics and the formation of a percolating network (gel phase) by realistically taking into account diffusion limitations, to extract scaling information at the percolation threshold and to recover the distribution of number of monomer units between two successive fully crosslinked units, from which the extent of swelling can be computed. The predictions of MC simulations are also successfully compared to a kinetic model based on numerical fractionation, with kinetic constants used as fitting parameters. MC data and kinetic simulations are compared to some exptl. data on the swelling behavior of polyacrylamide hydrogels and of poly(Me methacrylate) (PMMA) gels, exhibiting good agreement. We conclude that the proposed MC simulation scheme represents a powerful tool from which precious and exptl. inaccessible information on polymerization processes in the presence of crosslinkers can be extracted The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Recommanded Product: 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

The Article related to kinetic free radical crosslinking polymerization numerical, Chemistry of Synthetic High Polymers: Polymerization Kinetics, Mechanisms, Thermodynamics, Catalysis, Catalysts and other aspects.Recommanded Product: 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 2, 1997, Gilbert, Kevin; Williams, Peter D.; Evans, Ben E.; Hobbs, Doug W.; Veber, Daniel F. published a patent.Related Products of 53838-27-0 The title of the patent was Preparation of hydantoin and succinimide-substituted derivatives of spiroindanylcamphorsulfonylamides for use as oxytocin and vasopressin antagonists. And the patent contained the following:

Camphorsulfonylamides I and II [R = heterocyclyl such as imidazolyl, pyrrolidinyl, piperidinyl, piperazinyl, maleimido; R1 = H; R1R1 = bond] were prepared as oxytocin and vasopressin antagonists useful in the treatment of preterm labor, dysmenorrhea, and for the stoppage of labor preparatory to Cesarean delivery. Thus, endo-I [R = maleimido, R1 = H] was prepared starting from bis(2-chloroethyl)amine dihydrochloride, indene, (+)-10-camphorsufonyl chloride, and maleic anhydride and showed 70% inhibition of specific binding at 1000 nM in the [3H]OT binding assay. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Related Products of 53838-27-0

The Article related to camphorsulfonylamide preparation oxytocin receptor antagonist, vasopressin receptor antagonist spiroindanylcamphorsulfonylamide preparation, Terpenes and Terpenoids: Monoterpenes (C10), Including Cannabinoids, Chrysanthemic Acids, and Iridoid Aglycons and other aspects.Related Products of 53838-27-0

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On August 6, 2021, Zhao, Yingsheng; Jiangya, Qiqi; Shi, Daqing published a patent.Application of 141940-37-6 The title of the patent was Preparation of aniline para-trifluoromethyl derivative. And the patent contained the following:

The present invention relates to the preparation of aniline para-trifluoromethyl derivative In particular, the preparation method comprises the following steps: (1) adding aniline derivative, 4,5-dichlorofluorescein, potassium persulfate and sodium trifluoromethyl sulfinate in a glass reaction tube, and using DMSO as a solvent to react at room temperature (23-25°) under a 40W blue LED to obtain aniline para-trifluoromethyl derivative, and (2) after the reaction is completed, the product is separated and purified by column chromatog. to obtain the para-trifluoromethylated aniline derivative The present invention has following advantages: (1) the raw material is readily available in many kinds; (2) the products obtained by the method of the present invention are of various types and can be directly applied to the modification of drug mols.; (3) at the same time, the synthetic route is safe and easy, the cost is low, the reaction operation and post-treatment process is simple, the selectivity is good, the side reactions are few, and the reaction can be scaled up. The experimental process involved the reaction of tert-Butyl (4-(trifluoromethyl)phenyl)carbamate(cas: 141940-37-6).Application of 141940-37-6

The Article related to trifluoromethyl sulfinate aniline photochem trifluoromethylation, aniline trifluoromethyl derivative preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Application of 141940-37-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 31, 2010, Nielsen, Simon Dalsgaard; Smith, Garrick; Begtrup, Mikael; Kristensen, Jesper Langgaard published an article.Recommanded Product: tert-Butyl (4-(trifluoromethyl)phenyl)carbamate The title of the article was Amination of Aryl Iodides Using a Fluorous-Tagged Ammonia Equivalent. And the article contained the following:

A fluorous-tagged ammonia equivalent for the Cu-catalyzed amination of aryl iodides is described in which N-Boc-protected anilines are produced in high overall yield and purity. All purification steps are performed using Fluorous Solid-Phase Extraction (F-SPE) greatly simplifying and speeding up the isolation of the desired products. The experimental process involved the reaction of tert-Butyl (4-(trifluoromethyl)phenyl)carbamate(cas: 141940-37-6).Recommanded Product: tert-Butyl (4-(trifluoromethyl)phenyl)carbamate

The Article related to aryl iodide copper heptadecafluoroundecyloxy carbamic acid tertbutyl ester amination, aniline preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Recommanded Product: tert-Butyl (4-(trifluoromethyl)phenyl)carbamate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On August 8, 2018, Serratore, Nicholas A.; Anderson, Constance B.; Frost, Grant B.; Hoang, Truong-Giang; Underwood, Steven J.; Gemmel, Philipp M.; Hardy, Melissa A.; Douglas, Christopher J. published an article.Safety of Phenyl Salicylate The title of the article was Integrating Metal-Catalyzed C-H and C-O Functionalization To Achieve Sterically Controlled Regioselectivity in Arene Acylation. And the article contained the following:

One major goal of organometallic chemists is the direct functionalization of the bonds most recurrent in organic mols.: C-H, C-C, C-O, and C-N. An even grander challenge is C-C bond formation when both precursors are of this category. Parallel to this is the synthetic goal of achieving reaction selectivity that contrasts with conventional methods. Electrophilic aromatic substitution (EAS) via Friedel-Crafts acylation is the most renowned method for the synthesis of aryl ketones, a common structural motif of many pharmaceuticals, agrochems., fragrances, dyes, and other commodity chems. However, an EAS synthetic strategy is only effective if the desired site for acylation is in accordance with the electronic-controlled regioselectivity of the reaction. Herein we report steric-controlled regioselective arene acylation with salicylate esters via iridium catalysis to access distinctly substituted benzophenones. Exptl. and computational data indicate a unique reaction mechanism that integrates C-O activation and C-H activation with a single iridium catalyst without an exogenous oxidant or base. We disclose an extensive exploration of the synthetic scope of both the arene and the ester components, culminating in the concise synthesis of the potent anticancer agent hydroxyphenstatin. The experimental process involved the reaction of Phenyl Salicylate(cas: 118-55-8).Safety of Phenyl Salicylate

The Article related to steric controlled regioselective arene acylation salicylate ester iridium catalyst, exptl computational data reaction mechanism benzophenone preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ketones and Derivatives, Including Quinones and Sulfur Analogs and other aspects.Safety of Phenyl Salicylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 31, 2020, Hao, Xiaopeng; Song, Jian; Ding, Lei; Wen, Ping; Sun, Jianping; Liu, Yang; Yuan, Zundong; Duan, Yuning; Zhang, Yong published an article.COA of Formula: C13H10O3 The title of the article was Spaceborne radiance temperature standard blackbody for Chinese high-precision infrared spectrometer. And the article contained the following:

As a radiance temperature standard source for the Chinese high-resolution spectrum IR spectrometer, the National Institute of Metrol., China, developed a spaceborne radiance temperature standard blackbody (SRTSB) combined with a series of miniature phase change fixed points (MPCFPs) for temperature calibration and emissivity verification using a thermal radiation loop (TRL). The MPCFPs of the SRTSB contain H2O, Ga, Ga-Sn alloy, and Ph salicylate. The TRL is used to measure the emissivity of the spaceborne blackbody on the basis of controlling environmental radiation. Exptl. results show that the blackbody emissivity is higher than 0.998 and the temperature control stability is better than 5 mK. Temperature control uniformity at the cavity bottom and axial are better than or equal to 11 mK and 38 mK, resp., in the working temperature range of 268.15 K to 331.15 K.. The repeatability of the MPCFPs is less than 5 mK, and the results of the continuous phase transition of the MPCFPs are in a clear temperature plateau. The expanded uncertainty of the SRTSB is lower than or equal to 0.084 K (k = 2). The experimental process involved the reaction of Phenyl Salicylate(cas: 118-55-8).COA of Formula: C13H10O3

The Article related to spaceborne radiance temperature standard blackbody thermal radiation loop, Radiation Chemistry, Photochemistry, and Photographic and Other Reprographic Processes: Information Recording and Storage and other aspects.COA of Formula: C13H10O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 26, 2019, Kotammagari, Tharun K.; Paul, Sayantan; Bhattacharya, Asish K. published an article.Computed Properties of 2873-29-2 The title of the article was Unusual Epimerization in Styryllactones: Synthesis of (-)-5-Hydroxygoniothalamin, (-)-5-Acetylgoniothalamin, and O-TBS-Goniopypyrone. And the article contained the following:

(-)-5-Hydroxygoniothalamin (I, R = H), (-)-5-acetylgoniothalamin I (R = COMe), and (+)-5-hydroxygoniothalamin (II), isolated from the Goniothalamus genus, are synthesized from triacetyl-O-D-glucal by employing the Ferrier reaction, Mitsunobu reaction, and Jones oxidation as key steps. The synthetic procedure also yields the epimers of (-)-5-hydroxygoniothalamin and (+)-5-hydroxygoniothalamin employing acid-mediated transition-metal-free epimerization at C-5 of styryllactones. Further studies reveal that the epimerization is facilitated by the Ph group present on the styryllactones. Also, depending on the dihydroxylation reaction conditions, various analogs of saturated styryllactones are synthesized utilizing oxa-Michael reaction conditions. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Computed Properties of 2873-29-2

The Article related to hydroxygoniothalamin synthesis epimerization styryllactone, ferrier reaction mitsunobu epimerization jones oxidation hydroxygoniothalamin acetylgoniothalamin synthesis, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Computed Properties of 2873-29-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On May 1, 2020, Popadynec, Michael; Gibbard, Helen; Clark, J. Stephen published an article.Related Products of 2873-29-2 The title of the article was Bidirectional Synthesis of the IJK Fragment of Ciguatoxin CTX3C by Sequential Double Ring-Closing Metathesis and Tsuji-Trost Allylation. And the article contained the following:

A novel four-step bidirectional strategy has been used to synthesize the IJK fragment (I) of the marine polyether natural product CTX3C from a simple monocyclic precursor in a concise and efficient manner. The four-step bidirectional sequence involves ring-closing metathesis, alc. oxidation, enol carbonate formation, and palladium-mediated Tsuji-Trost allylation. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Related Products of 2873-29-2

The Article related to ring closing metathesis oxidation palladium tsuji trost allylation diastereoselective, ciguatoxin ijk fragment stereoselective preparation, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Related Products of 2873-29-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 17, 2022, Romiti, Filippo; Decultot, Ludovic; Clark, J. Stephen published an article.Electric Literature of 2873-29-2 The title of the article was Convergent Synthesis of the C1-C29 Framework of Amphidinolide F. And the article contained the following:

The complete carbon framework of the macrocyclic marine natural product amphidinolide F has been prepared by a convergent synthetic route in which three fragments of similar size and complexity have been coupled. Key features of the syntheses of the fragments include the stereoselective construction of the THF in the C1-C9 fragment by oxonium ylide (free or metal-bound) formation and rearrangement triggered by the direct generation of a rhodium carbenoid from 1-sulfonyl-1,2,3-triazole, the highly diastereoselective aldol reaction between a boron enolate and an aldehyde with 1,4-control to prepare the C10-C17 fragment, and the formation of the THF in the C18-C29 fragment by intramol. nucleophilic ring opening of an epoxide with a hydroxyl group under acidic conditions. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Electric Literature of 2873-29-2

The Article related to diastereoselective aldol rearrangement nucleophilic ring opening evans tishchenko, amphidinolide f framework synthesis, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Electric Literature of 2873-29-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics