Tag: 200-300

On August 7, 2019, Muramatsu, Wataru; Hattori, Tomohiro; Yamamoto, Hisashi published an article.Electric Literature of 53838-27-0 The title of the article was Substrate-directed Lewis-acid catalysis for peptide synthesis. And the article contained the following:

A Lewis-acid-catalyzed method for the substrate-directed formation of peptide bonds has been developed, and this powerful approach is utilized for the new “remote” activation of carboxyl groups under solvent-free conditions. The presented method has the following advantages: (1) the high-yielding peptide synthesis uses a tantalum catalyst for any amino acids; (2) the reaction proceeds without any racemization; (3) the new substrate-directed chem. ligation using the titanium catalyst is applicable to convergent peptide synthesis. These advantages overcome some of the unresolved problems in classical peptide synthesis. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Electric Literature of 53838-27-0

The Article related to peptide synthesis substrate directed lewis acid catalysis tantalum racemization, substrate directed ligation titanium catalyst solvent free neutralization solubility, Amino Acids, Peptides, and Proteins: Poly(Amino Acids) and Peptides and other aspects.Electric Literature of 53838-27-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 31, 2006, Kondratenko, R. M.; Baltina, L. A. Jr.; Baltina, L. A.; Baschenko, N. Zh.; Tolstikov, G. A. published an article.Product Details of 53838-27-0 The title of the article was Synthesis and immunomodulating activity of new glycopeptides of glycyrrhizic acid containing residues of L-glutamic acid. And the article contained the following:

New glycopeptides of glycyrrhizic acid [i.e., GA; (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-β-D-glucopyranuronosyl-α-D-glucopyranosiduronic acid], containing Glu residues and their α-Me esters, γ-Me esters, and α,γ-di-Me esters were synthesized using N,N’-dicyclohexylcarbodiimide in the presence of N-hydroxybenzotriazole or N-hydroxysuccinimide. Formation of amide bonds was observed on all the three COOH groups of GA, or selectively on the COOH groups of the GA carbohydrate part in dependence on the ratio of reagents and the reaction conditions. The GA glycopeptide with three residues of Glu(OH)-OMe at a dose of 2 mg/kg stimulated the production of antibody-forming cells in mouse spleen in comparison with the control. The GA glycopeptide containing Glu residues only in the GA carbohydrate part turned out to be an immunosuppressor. The glycopeptide of the 30-Me ester of GA with residues of free Glu in its carbohydrate part increased the hemagglutinin titer at oral doses of 2 and 10 mg/kg. All the studied compounds had practically no effect on the delayed-type hypersensitivity in mice. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Product Details of 53838-27-0

The Article related to immunomodulating activity glycopeptide glycyrrhizic glutamic acid preparation, licorice glycyrrhiza glabra glycopeptide glutamate preparation immunomodulator, Amino Acids, Peptides, and Proteins: Poly(Amino Acids) and Peptides and other aspects.Product Details of 53838-27-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On February 7, 2013, Babich, John W.; Zimmerman, Craig; Joyal, John L.; Lu, Genliang published a patent.Category: esters-buliding-blocks The title of the patent was Preparation of radiolabeled prostate specific membrane antigen inhibitors, particularly glutamate-urea-glutamates and glutamate-urea-lysines and their radionuclides conjugates, for diagnosis and treatment of diseases. And the patent contained the following:

The invention is related to the preparation of glutamate-urea-lysine (GUL) or glutamate-urea-glutamate (GUG) analogs in which a chelator group is conjugated to the GUL or GUG moiety via a linker, e.g., I, that are potent inhibitors of PSMA activity and to their radionuclides conjugates useful for treating or diagnosis of a disease or a condition associated with PSMA activity. Thus, I and its 111Lu-complex were prepared Biodistribution studies and affinity binding tests were conducted for the 111Lu complex. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Category: esters-buliding-blocks

The Article related to glutamate urea lysine peptide linker radionuclide conjugate psma inhibitor, radionuclide glutamate urea homodimer conjugate preparation tracer imaging agent, Amino Acids, Peptides, and Proteins: Poly(Amino Acids) and Peptides and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On February 28, 2010, Sicherl, Frank; Cupido, Tommaso; Albericio, Fernando published an article.Quality Control of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate The title of the article was A novel dipeptidomimetic containing a cyclic threonine. And the article contained the following:

An efficient and simple two-step procedure for the formation of hydroxy-Freidinger lactams is presented. The methodol. allows assembly of the cyclic threonine motif (cThr) in solution and on solid support during conventional peptide synthesis. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Quality Control of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

The Article related to peptidomimetic cyclic threonine synthesis hydroxy freidinger lactam, epoxide ring opening lactamization lactam solid phase peptide synthesis, Amino Acids, Peptides, and Proteins: Poly(Amino Acids) and Peptides and other aspects.Quality Control of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Claveau, Romain; Twamley, Brendan; Connon, Stephen J. published an article in 2018, the title of the article was Dynamic kinetic resolution of bis-aryl succinic anhydrides: enantioselective synthesis of densely functionalised γ-butyrolactones.SDS of cas: 29704-38-9 And the article contains the following content:

The efficient Dynamic Kinetic Resolution (DKR) of disubstituted anhydrides has been shown to be possible for the first time. Using an ad hoc designed organocatalyst and an enantio- and diastereoselective cycloaddition process with aldehydes, stereochem. complex γ-butyrolactone derivatives can be obtained – with control over three contiguous stereocentres, one of which is all carbon quaternary. The experimental process involved the reaction of tert-Butyl 2-(4-nitrophenyl)acetate(cas: 29704-38-9).SDS of cas: 29704-38-9

The Article related to butyrolactone enantioselective preparation, bisarylsuccinic anhydride preparation arylaldehyde dynamic kinetic resolution organocatalyst, Heterocyclic Compounds (One Hetero Atom): Pyrroles and Pyrrolizines and other aspects.SDS of cas: 29704-38-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On May 31, 2002, Gutheil, William G.; Xu, Qingchai published an article.HPLC of Formula: 53838-27-0 The title of the article was N-to-C solid-phase peptide and peptide trifluoromethylketone synthesis using amino acid tert-butyl esters. And the article contained the following:

Solid-phase peptide synthesis in the N-to-C direction, opposite to the classical C-to-N direction of peptide, synthesis, provides the synthetically versatile C-terminal carboxyl group for further modification into C-terminally modified peptide mimetics. These are of general interest as potential bioactive agents, particularly as protease inhibitors. Elaboration of peptide mimetics on the solid-phase would facilitate synthesis of peptide mimetic combinatorial libraries. This report describes an effective strategy for solid-phase inverse peptide synthesis based on readily available amino acid tert-Bu esters. The potential of this approach for peptide mimetic synthesis is demonstrated by the solid-phase synthesis of two peptide trifluoromethylketones. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).HPLC of Formula: 53838-27-0

The Article related to solid phase inverse peptide synthesis amino acid butyl ester, peptidomimetic peptide trifluoromethylketone solid phase inverse synthesis, Amino Acids, Peptides, and Proteins: Poly(Amino Acids) and Peptides and other aspects.HPLC of Formula: 53838-27-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On March 2, 1990, Agouridas, Constantin; Damais, Chantal; Fauveau, Patrick published a patent.Name: (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate The title of the patent was Preparation of glutamic acid derivatives as immunostimulants. And the patent contained the following:

HO2CCH(NH2)CH2C(:CH2)CH2CH(CO2H)NHCO(CH2)2CH(CO2H)NH-X-CO(CH2)16Me [I; X = bond, Ala], useful as an anticancer agents, antivirals, etc., are prepared E.g., I (X = Ala) was prepared in many steps via condensation of Me2CHCH2OC(O)OC(O)(CH2)2CH(CO2Me)NH-Ala-CO(CH2)16Me with EtO2CCH(NH2)CH2C(:CH2)CH2CH(NHCHO)CO2Et followed by hydrolysis. I stimulated the production of interleukin-1 and tumor necrosis factor in vitro. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Name: (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

The Article related to glutamic acid derivative preparation immunostimulant, anticancer glutamic acid derivative, antiviral glutamic acid derivative, Amino Acids, Peptides, and Proteins: Poly(Amino Acids) and Peptides and other aspects.Name: (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 24, 2021, Reddy, V. Veerabadhra; Reddy, B. V. Subba published an article.Safety of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate The title of the article was Azomethine ylide cycloaddition of 2-C-formyl glycals with α-amino acids for the synthesis of substituted pyrroles. And the article contained the following:

A novel strategy has been devised for the synthesis of pyrrole based acyclo-C-nucleosides, in particular an open-chain sugar substituted pyrrole derivatives by means of the condensation of 2-C-formyl glycals with α-amino acids through an intramol. azomethine cycloaddition under thermal conditions. The use of cyclic α-amino acids provides the corresponding bicyclic pyrrole derivatives This is a first report on the synthesis of pyrrole based acyclo-C-nucleosides. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Safety of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

The Article related to pyrrole acyclo nucleoside preparation, formyl glycal alpha amino acid condensation azomethine ylide cycloaddition, Heterocyclic Compounds (One Hetero Atom): Pyrroles and Pyrrolizines and other aspects.Safety of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 5, 2008, Fedorov, Andrei V.; Ermoshkin, Andrey A.; Neckers, Douglas C. published an article.Reference of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate) The title of the article was Remote polymerization of coatings with the release of borane from its amine complex. And the article contained the following:

We define remote polymerization as the formation of a photopolymer without the benefit of either light or a photoinitiator. In the reported experiments, a radical-generating trialkylborane-oxygen system was used with an active trialkylborane that was released from its stable amine complex by a vaporous (i.e., gas-phase) reagent. Acrylates and methacrylates were polymerized after oxidative radical formation from the highly reactive borane. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Reference of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

The Article related to remote radical polymerization coating borane release amine complex, Chemistry of Synthetic High Polymers: Organic Addition Polymerization and other aspects.Reference of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On February 28, 2022, Mimouni, Mourad; Bayou, Samir; Zeroual, Soria; Hamadneh, Imad; Mahboub, Mohammed Sadok; Ramdani, Soumia; Rihia, Ghani; Ghougali, Mebrouk published an article.SDS of cas: 2358-84-1 The title of the article was Synthesis and Characterization of Bulk Bi-2212 Superconducting Ceramic Using Photopolymerization Reaction-Based Method. And the article contained the following:

This study highlights the synthesis of Bi2Sr2CaCu2O8 (Bi-2212) superconducting ceramic using the photopolymerization reaction (PPR) and conventional solid-state reaction (SSR). The PPR sample was carried out by dissolving stoichiometric amounts of Bi, Sr, Ca, and Cu salts with the mixed monomer of DEGDMA and photoinitiator. The mixture was exposed to visible light, forming a rigid polymer. The resulted resin was calcined, palletized, and then sintered. The EDX measurements confirmed the average stoichiometry of the Bi-2212 phase. XRD confirmed the phase formation of the monoclinic phase with Bi 2212% exceeded 98%. SEM micrographs showed an irregular, flake-like structure with an average grain size (7.0μm). The elec. transport behavior for the prepared Bi 2212 showed metallic behavior with a single step feature where the offset temperature, TC(R=0) (65 K), in a single step feature. The PPR method will open the door for bulk HTSC ceramics that can be used for HTSC device applications. The experimental process involved the reaction of Oxybis(ethane-2,1-diyl) bis(2-methylacrylate)(cas: 2358-84-1).SDS of cas: 2358-84-1

The Article related to photopolymerization superconducting ceramic preparation property, Chemistry of Synthetic High Polymers: Organic Addition Polymerization and other aspects.SDS of cas: 2358-84-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics