Tag: 200-300

Sivergin, Yu. M.; Usmanov, S. M.; Shashkova, V. T.; Berlin, A. A.; Selenev, Yu. V. published an article in 1976, the title of the article was Nuclear resonance investigations on the molecular mobility in oligoester acrylates and polymers derived from them.Computed Properties of 1985-51-9 And the article contains the following content:

Application of the theory of R. Kubo and K. Tomita (1954) to correlation times for α- and β’-relaxations in oligoester acrylates [1,3-propanediol bis(2-hydroxyethyl carbonate) dimethacrylate [60028-80-0], neopentylglycol bis(2-hydroxyethyl carbamate) dimethacrylate [54547-48-7], 2,2-bis(chloromethyl)-1,3-propanediol bis(2-hydroxyethyl carbonate) dimethacryalate [54547-50-1], neopentyl glycol dimethacrylate [1985-51-9]] and the corresponding polymers determined by NMR gave relatively low correlation values when compared with data from dielec. and mech. measurements. Application of the K.-T. theory is not justified, since is applies only to spherical mols. undergoing rotational Brownian movement, and not to 3-dimensional polymers. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Computed Properties of 1985-51-9

The Article related to relaxation oligoester methacrylate, nmr relaxation oligoester methacrylate, mobility oligoester methacrylate, acrylate oligoester relaxation, Synthetic High Polymers: Physical Properties Of Polymers and other aspects.Computed Properties of 1985-51-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 15, 2020, Uto, Takuya; Nakamura, Shota; Yamamoto, Kazuya; Kadokawa, Jun-ichi published an article.Application In Synthesis of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate The title of the article was Evaluation of artificial crystalline structure from amylose analog polysaccharide without hydroxy groups at C-2 position. And the article contained the following:

In this study, we found that a new artificial crystalline structure was fabricated from an amylose analog polysaccharide without hydroxy groups at the C-2 position, i.e., 2-deoxyamylose. The polysaccharide with a well-defined structure was synthesized by facile thermostable α-glucan phosphorylase-catalyzed enzymic polymerization Powder X-ray diffraction (XRD) anal. of the product indicated the formation of a specific crystalline structure that was completely different from the well-known double helix of the natural polysaccharide, amylose. Mol. dynamics simulations showed that the isolated chains of 2-deoxyamylose spontaneously assembled to a novel double helix based on building blocks with controlled hydrophobicity arising from pyranose ring stacking. The simulation results corresponded with the XRD patterns. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Application In Synthesis of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

The Article related to polysaccharide amylose crystalline structure mol dynamics simulation, amylose, helical structures, molecular dynamics, polysaccharides, Industrial Carbohydrates: Starches and Their Derivatives and other aspects.Application In Synthesis of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mohr, Margaret A.; Wong, Angela M.; Sukumar, Gauthaman; Dalgard, Clifton L.; Hong, Weizhe; Wu, T. John; Wu, Ye Emily; Micevych, Paul E. published an article in 2021, the title of the article was RNA-sequencing of AVPV and ARH reveals vastly different temporal and transcriptomic responses to estradiol in the female rat hypothalamus.Recommanded Product: Oxybis(ethane-2,1-diyl) bis(2-methylacrylate) And the article contains the following content:

In females, estrogens have two main modes of action relating to gonadotropin secretion: pos. feedback and neg. feedback. Estrogen pos. and neg. feedback are controlled by different regions of the hypothalamus: the preoptic area/anterior portion (mainly the anteroventral periventricular nucleus, AVPV) of the hypothalamus is associated with estrogen pos. feedback while the mediobasal hypothalamus (mainly the arcuate nucleus of the hypothalamus, ARH), is associated with estrogen neg. feedback. In this study, we examined the temporal pattern of gene transcription in these two regions following estrogen treatment. Adult, ovariectomized, Long Evans rats received doses of estradiol benzoate (EB) or oil every 4 days for 3 cycles. On the last EB priming cycle, hypothalamic tissues were dissected into the AVPV+ and ARH+ at 0 h (baseline/oil control), 6 h, or 24 h after EB treatment. RNA was extracted and sequenced using bulk RNA sequencing. Differential gene anal., gene ontol., and weighted correlation network anal. (WGCNA) was performed. Overall, we found that the AVPV+ and ARH+ respond differently to estradiol stimulation. In both regions, estradiol treatment resulted in more gene up-regulation than down-regulation. S100g was very strongly up-regulated by estradiol in both regions at 6 and 24 h after EB treatment. In the AVPV+ the highest number of differentially expressed genes occurred 24 h after EB. In the ARH+, the highest number of genes differentially expressed by EB occurred between 6 and 24 h after EB, while in the AVPV+, the fewest genes changed their expression between these time points, demonstrating a temporal difference in the way that EB regulates transcription these two areas. Several genes strongly implicated in gonadotropin release were differentially affected by estradiol including Esr1, encoding estrogen receptor-α and Kiss1, encoding kisspeptin. As an internal validation, Kiss1 was up-regulated in the AVPV+ and down-regulated in the ARH+. Gene network anal. revealed the vastly different clustering of genes modulated by estradiol in the AVPV+ compared with the ARH+. These results indicate that gene expression in these two hypothalamic regions have specific responses to estradiol in timing and direction. The experimental process involved the reaction of Oxybis(ethane-2,1-diyl) bis(2-methylacrylate)(cas: 2358-84-1).Recommanded Product: Oxybis(ethane-2,1-diyl) bis(2-methylacrylate)

The Article related to estradiol rat hypothalamus avpv arh rna sequencing temporal transcriptomics, Mammalian Biochemistry: Classical Genetics and Phylogeny and other aspects.Recommanded Product: Oxybis(ethane-2,1-diyl) bis(2-methylacrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 31, 1978, Fujisawa, S.; Imai, Y.; Kojima, K.; Masuhara, E. published an article.Related Products of 1985-51-9 The title of the article was Studies on hemolytic activity of bisphenol A diglycidyl methacrylate (BIS-GMA). And the article contained the following:

To clarify the high hemolytic activity of Bis-GMA (I) [1565-94-2], the molar concentrations production 50% hemolysis (H50) and the partition coefficient in octanol-water were determined using I and various types of methacrylates. The strong hemolytic potency of I is probably due to the high hydrophobic nature of the compound The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Related Products of 1985-51-9

The Article related to dental methacrylate resin hemolysis, glycidyl methacrylate hemolysis, Pharmacodynamics: Effects On Test Systems and Nonmammals and other aspects.Related Products of 1985-51-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 30, 2021, Sun, Guanqing; Wu, Xingyi; Liu, Ren published an article.Computed Properties of 2358-84-1 The title of the article was A comprehensive investigation of acrylates photopolymerization shrinkage stress from micro and macro perspectives by real time MIR-photo-rheology. And the article contained the following:

The acrylate photocuring system with the high curing rate are widely used in various industries. However, the rapid polymerization kinetics can cause the surge of resin viscosity and the gel point can be reached in advance. This can results in the restriction of mol. chain movement and internal stress release is thus hindered during the photopolymerization Finally, it usually leads to the poor performance of UV-cured materials with lower double bond conversion and large volume shrinkage and shrinkage stress. In order to understand the relationship between properties and polymerization process, this paper employed the combined technique of the mid-IR spectrometer and photo-rheometer to monitor the acrylate free radical photopolymerization process. The effects of curing conditions (curing temperature, radiant intensity and sample thickness) and system compositions (diluent functionality, diluent segment length) on the rheol. properties and chem. conversion of materials were fully investigated. Finally, a standard protocol is established to evaluate the reactivity, mech. properties and volume shrinkage of the photocuring system. Simultaneously, the double bond conversion of the reaction system can be achieved through calculation of peak area of IR absorption. A complex nonlinear relationship between the storage modulus, shrinkage stress and double bond conversion is established. The experimental process involved the reaction of Oxybis(ethane-2,1-diyl) bis(2-methylacrylate)(cas: 2358-84-1).Computed Properties of 2358-84-1

The Article related to acrylate photopolymerization shrinkage stress rheol property, Coatings, Inks, and Related Products: Epoxy Resin Coatings and other aspects.Computed Properties of 2358-84-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 17, 1974, Wuensch, Erich; Wendlberger, Gerhard; Jaeger, Ernst; Scharf, Regine; Deimer, Karl H.; Stocker, Hans published a patent.Name: (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate The title of the patent was Norleucine-13-motiline. And the patent contained the following:

Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Glu-Arg-Nle-Glu-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln (I) was prepared by successive coupling and deblocking of Arg(HBr)-Asn-Lys(CO2CMe3)-Gly-Gln-OCMe3.HBr, PhCH2O2C-Glu(OCMe3)-Glu(OCMe3)-Lys-(CO2CMe3)-Glu(OCMe3)-OH, PhCH2O2C-Arg[δ,ω – (CO2CH2Ph)2]Nle-OH, PhCH2O2C-Glu(OCMe3)-Leu-Gln-OH, Thr(CMe3)-Tyr(CMe3)-Gly-OH, and Me3CO2C-Phe-Val-Pro-Ile-Phe-OH, which were prepared by standard coupling methods. I, after purification on ion exchange resin, had 90% of the activity of naturally occurring motilin. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Name: (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

The Article related to motilin norleucine analog, stomach motilin norleucine analog, Synthesis of Amino Acids, Peptides, and Proteins: Peptides and other aspects.Name: (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Moroder, Luis; Borin, Gianfranco; Filippi, Bruno; Stivanello, Diego; Marchiori, Fernando published an article in 1977, the title of the article was Studies on cytochrome c. XII. Synthesis of the protected undecapeptide (sequence 66-76) and pentadecapeptide (sequence 66-80) of horse heart cytochrome c.COA of Formula: C10H19NO4 And the article contains the following content:

Z-Glu-Tyr-Leu-Glu-Asn-Pro-Lys(TFA)-Lys(TFA)-Tyr-Ile-Pro-NHNH2 (I; Z = PhCH2O2C, TFA = CF3CO), the protected 66-76 fragment of horse heart cytochrome c was prepared by coupling Z-Glu(OCMe3)-Tyr-Leu-Glu(OCMe3)-NHNH2 (II) to H-Asn-Pro-Lys(TFA)-Lys(TFA)-Tyr(CMe3)-Ile-Pro-NHNHCO2CMe3 by the azide method and partially deblocking the resulting undecapeptide with CF3CO2H. I was coupled to H-Gly-Thr(CMe3)-Lys(TFA)-Met-NHNHCO2Me3 (III) by the azide method to give the corresponding protected pentadecapeptide which was the protected 66-80 fragment of cytochrome c. II and III were prepared by conventional stepwise peptide couplings. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).COA of Formula: C10H19NO4

The Article related to cytochrome c undecapeptide pentadecapeptide synthesis, Synthesis of Amino Acids, Peptides, and Proteins: Peptides and other aspects.COA of Formula: C10H19NO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 1, 2015, Brownstein, Michael J. published a patent.Reference of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate The title of the patent was Preparation of substituted azetidinone derivatives for use in the treatment of neurodegenerative diseases. And the patent contained the following:

Title compounds I [A = carboxylic acid, ester, or amide; D = carboxylic acid, ester, amide, alc., or thiol; R1 = H or alkyl; R2 = H, CN, halo, alkyl, etc.; R3 = (un)substituted amino, amido, acylamido, etc.], and their pharmaceutically acceptable salts, are prepared and disclosed for use in the treatment of neurodegenerative diseases. Thus, e.g., II was prepared by a multistep procedure (preparation given). Select I were evaluated in Via receptor binding assays, e.g., II demonstrated an IC50 value of 2.92 nM. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Reference of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

The Article related to azetidinone preparation neurodegenerative disease, Heterocyclic Compounds (One Hetero Atom): 4-Membered Rings and other aspects.Reference of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On March 21, 2019, Brownstein, Michael J. published a patent.Application In Synthesis of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate The title of the patent was Preparation of azetidinone derivatives for use in treating brain injury. And the patent contained the following:

Title compounds I [A = CO2H, ester, or amide; B = OH, SH, CO2H, ester, or amide; R1 = H or alkyl; R2 = H, halo, CN, alkyl, alkoxy, etc.; R3 = amino, amido, acylamido, (un)substituted ureido, etc.; R4 = alkyl, (un)substituted aryl, arylalkyl, etc.], and their pharmaceutically acceptable salts, are prepared and disclosed for use in treating brain injurys. Thus, e.g., II was prepared by a multistep procedure (preparation given). Select I were evaluated in V1a binding assays, e.g., II demonstrated an IC50 value of 0.49 nM. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Application In Synthesis of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

The Article related to azetidinone preparation brain injury, Heterocyclic Compounds (One Hetero Atom): 4-Membered Rings and other aspects.Application In Synthesis of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 7, 1977, Wuensch, Erich; Wendlberger, Gerhard; Jaeger, Ernst published a patent.COA of Formula: C10H19NO4 The title of the patent was L-Leucine-13-motiline. And the patent contained the following:

H-Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Glu-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln-OH (I), 13-L-leucine-motiline, was prepared by peptide fragment condensations. Thus, Z-Asn-Lys(BOC)-OH (Z = PhCH2O2C, BOC = Me3CO2C) and H-Gly-Gln-OCMe3 were prepared and coupled together by dicyclohexylcarbodiimide (DCC) in the presence of N-hydroxysuccinimide (HOSu) to give the protected tetrapeptide. The latter was Z-deblocked by hydrogenation and then coupled to Z-Arg(Z2)-OC6H4NO2-4 to give the protected pentapeptide which was hydrogenated and treated with HBr to give H-Arg-Asn-Lys(BOC)-Gly-Gln-OCMe3.2HBr (II), the protected 18-22 sequence of I. Z-Glu(OCMe3)-Glu(OCMe3)-Lys(BOC)-Glu(OCMe3)-OH (III), the 14-17 sequence, Z-Arg(Z2)-Leu-OH (IV), the 12-13 sequence, Z-Glu(OCMe3)-Leu-Gln-OH (V), the 9-11 sequence, H-Thr(CMe3)-Tyr(CMe3)-Gly-OH (VI), the 6-8 sequence, and BOC-Phe-Val-Pro-Ile-Pro-OH (VII), the 1-5 sequence, were also prepared II was coupled to III by DCC-HOSu to give the protected 14-22 sequence which was Z-deblocked and coupled to IV by DCC-HOSu to give the protected 12-22 sequence. The latter was Z-deblocked and coupled to V by DCC-HOSu to give the protected 9-11 sequence which was Z-deblocked and coupled to the protected 1-8 sequence to give the protected 1-22 sequence. The latter was deblocked with CF3CO2H to give I. The protected 1-8 sequence was prepared by coupling VI to VII by the HOSu active ester. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).COA of Formula: C10H19NO4

The Article related to leucine motiline, peptide motiline, Synthesis of Amino Acids, Peptides, and Proteins: Peptides and other aspects.COA of Formula: C10H19NO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics