Tag: 200-300

Dondoy, J.; Alloing-Bernard, A.; Renson-Deneubourg, C. published an article in 1971, the title of the article was Functional analysis and gas-chromatographic separation of perfluorinated mono- and diesters of diols.Application In Synthesis of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate) And the article contains the following content:

Functional analysis. methods for fluorinated esters are discussed. Perfluorocarboxylic acid esters, such as Et perfluorooctanoate, are titrated in neutralized EtOH with 0.5N alc. KOH. The error for the above compound was ±1.8%. The classical saponification method must be used for esters F3C(CF2)nCH2CO2R (R = alkyl). When the above method is used for ethylene glycol acrylate perfluorooctanoate it specifically determines the perfluorinated acid. Hydroxyl numbers are determined by HClO4-catalyzed acetylation, and residual acidity by NH4OH titration For chromatog. of the esters a suitable stationary phase is Plastinol on a Gas Pack F support. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Application In Synthesis of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

The Article related to perfluorinated ester functional analysis, acid number perfluorocarboxylic ester, hydroxyl number perfluorocarboxylic ester, functional groups and other aspects.Application In Synthesis of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On March 6, 2020, Yang, Jiebin; Lian, Yikai; Yang, Renzhi; Lian, Yifan; Wu, Jingtong; Liu, Jingjing; Wang, Keming; Xu, Hongzhi published an article.Formula: C12H18O5 The title of the article was Upregulation of lncRNA LINC00460 Facilitates GC Progression through Epigenetically Silencing CCNG2 by EZH2/LSD1 and Indicates Poor Outcomes. And the article contained the following:

Non-protein-coding functional elements in the human genome in the postgenomic biol. field have been drawing great attention in recent years. Thousands of long non-coding RNAs (lncRNAs) have been found to be expressed in various tumors. Yet only a small proportion of these lncRNAs have been well characterized. We have demonstrated that LINC00460 could affect cell proliferation through epigenetic regulation of KLF2 and CUL4A in human colorectal cancer. However, the clin. significance and biol. role of LINC00460 in gastric cancer (GC) remain largely unknown. In this research, we discovered that LINC00460 is remarkably upregulated in GC tissues compared to the non-tumor tissues. Addnl., LINC00460 served as an independent prognostic marker in GC. Functionally, proliferation of GC cells could be regulated by LINC00460 both in vitro and in vivo. RNA sequencing (RNA-seq) anal. for the whole transcriptome indicated that LINC00460 may serve as a key regulatory factor in the tumorigenesis of GC. What′s more, the biol. function of LINC00460 was mediated, to certain extent, by the direct interaction with enhancer of zeste homolog 2 (EZH2) and lysine (K)-specific demethylase 1A (LSD1) proteins. Further analyses indicated that LINC00460 promoted GC proliferation at least partly through the downregulation of tumor suppressor-gene Cyclin G2 (CCNG2), which is mediated by EZH2 and LSD1. In conclusion, our results suggested that LINC00460 acted as an oncogene in GC to inhibit the expression of CCNG2 at least partly by binding with EZH2 and LSD1. Our study could provide addnl. insights into the development of novel target therapeutic methods for GC. The experimental process involved the reaction of Oxybis(ethane-2,1-diyl) bis(2-methylacrylate)(cas: 2358-84-1).Formula: C12H18O5

The Article related to transcriptome linc00460 ccng2 ezh2 lsd1 silencing gastric cancer progression, ezh2, linc00460, lsd1, gastric cancer, proliferation, and other aspects.Formula: C12H18O5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Loshaek, S. published an article in 1955, the title of the article was Cross-linked polymers. II. Glass temperatures of copolymers of methyl methacrylate and glycol dimethacrylates.Formula: C13H20O4 And the article contains the following content:

cf. C.A. 47, 11800h. Glass temperatures (Tg) were determined for copolymers of Me methacrylate and from 0 to 100% of the dimethacrylates of ethylene glycol (I), decamethylene glycol (II), and 2-ethyl-2-butyl-1,3-propanediol (III), and for copolymers containing 0-17 mole % of the dimethacrylate of 2,2-dimethylpropanediol. Maximum were observed in the Tg-mole fraction of dimethacrylate for the II and III copolymers. The results were considered to be caused by changes in both average copolymer composition and degree of cross-linking. The former was evaluated for I from the observed Tg-composition relation for copolymers of Me methacrylate with ethylene glycol monomethacrylate monoisobutyrate. Assuming additivity, cross-linking alone was found to increase Tg linearly with the degree of cross-linking, the proportionality constant being of the same order of magnitude as reported for styrenedivinylbenzene copolymers (cf. preceding abstract). The magnitude of the increase in Tg was independent of the nature of the cross-linking agent. The experimental process involved the reaction of 2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas: 1985-51-9).Formula: C13H20O4

2,2-Dimethylpropane-1,3-diyl bis(2-methylacrylate)(cas:1985-51-9) belongs to ethers. Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however. Formula: C13H20O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Newman, Melvin S.; Beal, Philip F. III published an article in 1950, the title of the article was Improved Wolff rearrangement in homogeneous medium.HPLC of Formula: 29704-38-9 And the article contains the following content:

The Wolff rearrangement of α-diazo ketones to esters with MeOH and Ag2O gives erratic results. BzOAg (1 g.) in 9.1 g. NEt3 with the diazo ketone in MeOH works much better. The basic properties of NEt3 seem important, as F3CCO2Ag in C6H6 did not react. The reaction can be inhibited by a solution of hydroquinone. The presence in the diazo ketone of a H in the α-position to both the carbonyl and the diazo group is necessary. A possible reaction mechanism is presented. tert-Bu p-nitrophenylacetate b10 164-8°. The experimental process involved the reaction of tert-Butyl 2-(4-nitrophenyl)acetate(cas: 29704-38-9).HPLC of Formula: 29704-38-9

tert-Butyl 2-(4-nitrophenyl)acetate(cas:29704-38-9) belongs to ethers. Oxygen is more electronegative than carbon, thus the alpha hydrogens of ethers are more acidic than those of simple hydrocarbons. They are far less acidic than alpha hydrogens of carbonyl groups (such as in ketones or aldehydes), however. HPLC of Formula: 29704-38-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 14, 2020, Zheng, Lifang; Luo, Yan; Chen, Kui; Zhang, Zexin; Chen, Gaojian published an article.Product Details of 2358-84-1 The title of the article was Highly Branched Gradient Glycopolymer: Enzyme-Assisted Synthesis and Enhanced Bacteria-Binding Ability. And the article contained the following:

A one-pot strategy was applied to synchronize enzymic monomer transformation with reversible addition fragmentation chain transfer (RAFT) polymerization for the synthesis of glycopolymers with highly branched gradient architectures. Also, the linear analogs, block glycopolymers, and gradient glycopolymers were also synthesized for comparison. The binding ability of glycopolymers toward bacteria was then studied by optical d. (OD) test, confocal laser scanning microscopy (CLSM), and quartz crystal microbalance with dissipation (QCM-D). The results show that the highly branched gradient glycopolymers have the most remarkable bacteria-binding ability compared with the two linear analogs, gradient glycopolymers, and block glycopolymers. The highly branched glycopolymers were further used as inhibitors in the anti-infection test, demonstrating a significant inhibitory effect on preventing bacteria from infecting the cells. The experimental process involved the reaction of Oxybis(ethane-2,1-diyl) bis(2-methylacrylate)(cas: 2358-84-1).Product Details of 2358-84-1

The Article related to highly branched glycopolymer preparation, Pharmaceuticals: Other and other aspects.Product Details of 2358-84-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ahmed, Ajaz; Sakander, Norein; Rasool, Faheem; Hussain, Nazar; Mukherjee, Debaraj published an article in 2022, the title of the article was Diastereoselective synthesis of glycopyrans 1,2-annulated with dioxazinanes from 1,2-anhydrosugars and N-substituted nitrones.Product Details of 2873-29-2 And the article contains the following content:

1,2-Annulated pyranose sugars fused with six membered rings, e.g. I, have emerged as an important class of carbohydrates with wide biol. and synthetic utility. We now describe zinc chloride catalyzed one pot diastereoselective synthesis of sugar fused dioxazinanes from 1,2-anhydro sugars and N-substituted aromatic nitrones. Various aromatic nitrones with different substituents undergo the reaction smoothly. The developed strategy works well with both ester and ether protection on the sugar and proceeds under mild reaction conditions. The mechanism seems to involve activation of the anhydrosugar by ZnCl2 for nucleophilic attack by the nitrone followed by cyclization. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Product Details of 2873-29-2

The Article related to stereoselective cyclization nucleophilic anhydrosugar dioxazinane glycopyran synthesis nitrone glycoside, Carbohydrates: Amines and other aspects.Product Details of 2873-29-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 17, 2020, Fukuhara, Ippei; Matsubara, Ryosuke; Hayashi, Masahiko published an article.SDS of cas: 2873-29-2 The title of the article was Selective Synthesis of Some Aminosugars via Catalytic Aminohydroxylation of Protected 2,3-Unsaturated D-Gluco- and D-Galacto-2-hexenopyranosides. And the article contained the following:

The aminohydroxylation of Me 4,6-di-O-(tert-butyldimethylsilyl)-2,3-unsaturated α-D-glucopyranoside proceeds in the presence of chloramine-T, OsO4 (4 mol %), (DHQ)2PHAL (5 mol %), and triethylbenzylammonium chloride (TEBAC) in both a stereoselective and a regioselective manner to produce protected Me α-D-mannosamide as the sole product. In contrast, the reaction of Me 2,3-unsaturated β-D-galactopyranoside under the same conditions produced a mixture of regioisomers, although the stereochem. was perfectly controlled. The regioisomeric ratio was dependent on the nature of the protecting group and the ligand used. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).SDS of cas: 2873-29-2

The Article related to aminohydroxylation catalyst aminosugar glycoside preparation ethylbenzylammonium chloride chloramine, Carbohydrates: Amines and other aspects.SDS of cas: 2873-29-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 18, 2006, Aagren, Jenny K. M.; Billing, Johan F.; Grundberg, Hans E.; Nilsson, Ulf J. published an article.Synthetic Route of 53838-27-0 The title of the article was Synthesis of a chiral and fluorescent sugar-based macrocycle by 1,3-dipolar cycloaddition. And the article contained the following:

An efficient and modular synthesis of a chiral, amphiphilic, and fluorescent macrocycle is described. A bis-acetylene was prepared by coupling the amino group of a sugar δ-amino acid with a glutamic acid propargylic amide derivative, followed by coupling of the sugar δ-amino acid carboxy group with a glutamic acid propiolyl amide. The bis-acetylene was reacted with 9,10-bis(azidomethyl)anthracene under Cu(I) catalysis to afford the target fluorescent macrocycle. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Synthetic Route of 53838-27-0

The Article related to amphiphilic fluorescent glycoside macrocycle preparation dipolar cycloaddition, Carbohydrates: Amines and other aspects.Synthetic Route of 53838-27-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 15, 1980, Johansen, Jack Taaning; Widmer, Fred published a patent.SDS of cas: 53838-27-0 The title of the patent was Enzymic production of peptides. And the patent contained the following:

Peptides are produced by reacting amino acid esters, peptide esters, depsipeptides, etc., with an amino acid in the presence of carboxypeptidase in an aqueous solution with a pH of 5-10.5. Thus, a valine [72-18-4]-KCl-EDTA solution, pH 9.8, was mixed with a Bz-Ala-OMe [7244-67-9] solution and the reaction carried out in a pH-stat at 35° with the pH maintained by the addition of NaOH. The reaction was initiated by adding carboxypeptidase Y [9046-67-7]. It was stopped after sufficient time by the addition of HCl to lower the pH to 1.0. The reaction product was purified and isolated by high-pressure chromatog. giving a 40% yield of Bz-Ala-Val-OH [71448-06-1]. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).SDS of cas: 53838-27-0

The Article related to peptide production carboxypeptidase, amino acid peptide production enzyme, amide peptide production enzyme, Fermentations: Other and other aspects.SDS of cas: 53838-27-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On August 27, 2020, Lafuente, Leticia; Rojas, Agustin H.; Piro, Oscar E.; Echeverria, Gustavo A.; Ponzinibbio, Agustin published an article.Reference of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate The title of the article was Synthesis, NMR and X-ray studies on novel heteroaromatic aldoxime O-ether 2- and 2,3-unsaturated glycosides. And the article contained the following:

We present the synthesis of novel hydrolytically stable heteroaromatic oxime ether glycosides in very good yields and high anomeric selectivity. The products obtained are α-glycosides and the double bond configuration is E. The aldoxime O-ether carbohydrate derivatives were analyzed by structural X-ray diffraction and NMR spectral data. A complete investigation on the glycoside structures, that includes conformation characteristics in the pyranose ring and heterocyclic alternative positions, is also described. The experimental process involved the reaction of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate(cas: 2873-29-2).Reference of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

The Article related to heteroaromatic aldoxime ether unsat glycoside preparation nmr conformational, Carbohydrates: Glycosides and other aspects.Reference of (2R,3S,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics