Tag: 100-200

Quality and volatile organic compounds emission alterations in ‘August Flame’ peaches due to low dose methyl bromide fumigation was written by Torregrosa, Laia;Illa, Josep;Allen, David;Stefanelli, Dario. And the article was included in Scientia Horticulturae (Amsterdam, Netherlands) in 2021.Quality Control of 5-Ethyldihydrofuran-2(3H)-one This article mentions the following:

As all perishable fruit, peaches must be stored in cold temperature during transportation for maintenance of fruit quality. Australian peaches exported to China must undergo fumigation quarantine treatments prior to shipment for biosecurity reasons. August Flame peaches were fumigated with Me bromide (MB) at the low dosage of 18 g/m3 for 5.5 h at flesh temperature of 18°C, as a biosecurity disinfestation treatment, with a subsequent cold storage period at 2°C and 4°C for 5 and 9 d to simulate air freight transportation. Fruit quality parameters measured during shelf life (SL) were: firmness, index of delta absorbance (IAD), ethylene production and respiration. Four families of volatile organic compounds (VOCs) from samples of fruit flesh and skin were analyzed along SL: aldehydes, alcs., esters and lactones. Overall trends in the evolution of quality parameters and VOCs emissions were identified. Fumigation, under our exptl. conditions, anticipated the climacteric ethylene peak, but did not affect fruit quality enough to be detrimental for consumption and did not cause skin or internal disorders. During SL aldehydes decreased, lactones increased, alcs. were higher in skin than in flesh, but none of these general trends were clearly affected by the fumigation. In the experiment, the researchers used many compounds, for example, 5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7Quality Control of 5-Ethyldihydrofuran-2(3H)-one).

5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Quality Control of 5-Ethyldihydrofuran-2(3H)-one

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and antineoplastic properties of (1H-1,2,3-triazol-1-yl)furazans was written by Kulikov, A. S.;Epishina, M. A.;Batog, L. V.;Rozhkov, V. Yu.;Makhova, N. N.;Konyushkin, L. D.;Semenova, M. N.;Semenov, V. V.. And the article was included in Russian Chemical Bulletin in 2013.Recommanded Product: 13669-10-8 This article mentions the following:

A method of 3-amino-4-[5-aryl(heteroaryl)-1H-1,2,3-triazol-1-yl]furazan synthesis was optimized. Condensation of these compounds with 2,5-dimethoxytetrahydrofuran resulted in a series of novel 4-[5-aryl(heteroaryl)-1H-1,2,3-triazol-1-yl]-3-(pyrrol-1-yl)furazans. All target compounds were evaluated for both antimitotic microtubule destabilizing in a phenotypic sea urchin embryo assay and cytotoxicity in human cancer cell lines. The pyrrolyl derivatives of triazolylfurazans were determined as antiproliferative compounds The most potent microtubule targeting compounds, 4-[5-(4-methoxyphenyl)- and -5-(4-ethoxyphenyl)-1H-1,2,3-triazol-1-yl]-3-(pyrrol-1-yl)furazan showed potential as antineoplastic agents. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Recommanded Product: 13669-10-8).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 13669-10-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of enzymatic aroma release on the volatile compounds of white wines presenting different aroma potentials was written by Rocha, Silvia M.;Coutinho, Paula;Delgadillo, Ivonne;Cardoso, Antonio Dias;Coimbra, Manuel A.. And the article was included in Journal of the Science of Food and Agriculture in 2005.Formula: C11H14O3 This article mentions the following:

Wines from Maria Gomes (Fernao Pires) and Bical varieties were treated with an enzymic preparation, Lallzyme de Lalvin, with β-glucosidase, pectinase, arabinosidase and rhamnosidase activity. The reference and enzyme-treated wines were, submitted to a process of continuous liquid-liquid extraction with dichloromethane and analyzed by GC-MS. The volatile contents of the wines were 199 and 188 mg1^-1, resp., for Maria Gomes and Bical. Both varieties contained aliphatic and aromatic alcs., terpenoids, esters, aliphatic acids and lactones. Enzymically treated wines showed an increase of 9% in the total amount of volatile compounds of Maria Gomes, due, mainly, to the increase of geraniol (67%), terpene diols (96%), phenols and aromatic alcs. (26%) and esters (32%). Some of them were within their perception limits and may have a contribution to the floral and fruity notes. Conversely, no significant modifications were introduced by enzymic treatment in the total amount of volatile compounds of Bical wine. The presence of aromatic alcs. in significant amounts, which may represent an interesting characteristic in Bical wines, was not increased by the treatment used. This study with two white varieties grown in the same Appellation shows that the effectiveness of aroma release by enzymic treatment, using a broad range of enzymic activities, is closely dependent on the varietal aroma potential, knowledge of which is a key determinant for full exploitation of wine qualities. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Formula: C11H14O3).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Formula: C11H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Discovery of imidazopyridine derivatives as novel c-Met kinase inhibitors: Synthesis, SAR study, and biological activity was written by Yang, Yifei;Zhang, Yuan;Yang, Ling Yun;Zhao, Leilei;Si, Lianghui;Zhang, Huibin;Liu, Qingsong;Zhou, Jinpei. And the article was included in Bioorganic Chemistry in 2017.Recommanded Product: 14667-47-1 This article mentions the following:

Receptor tyrosine kinase c-Met acts as an alternative angiogenic pathway in the process and contents of cancers. A series of imidazopyridine derivatives were designed and synthesized according to the established docking studies as possible c-Met inhibitors. Most of these imidazopyridine derivatives displayed nanomolar potency against c-Met in both biochem. enzymic screens and cellular pharmacol. studies. Especially, compound 7 g exhibited the most inhibitory activity against c-Met with IC₅₀ of 53.4 nM and 253 nM in enzymic and cellular level, resp. Following that, the compound 7 g was docked into the protein of c-Met and the structure-activity relationship was analyzed in detail. These findings indicated that the novel imidazopyridine derivative compound 7 g was a potential c-Met inhibitor deserving further investigation for cancer treatment. In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1Recommanded Product: 14667-47-1).

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 14667-47-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Insights into crucial odourants dominating the characteristic flavour of citrus-white teas prepared from citrus reticulata Blanco ‘Chachiensis’ and Camellia sinensis ‘Fudingdabai’ was written by Wang, Jiatong;Shi, Jiang;Zhu, Yin;Ma, Wanjun;Yan, Han;Shao, Chenyang;Wang, Mengqi;Zhang, Yue;Peng, Qunhua;Chen, Yuqiong;Lin, Zhi. And the article was included in Food Chemistry in 2022.Synthetic Route of C10H18O2 This article mentions the following:

Citrus-white teas (CWs), which possess a balanced flavor of tea and citrus, are becoming more popular worldwide; however, their characteristic flavor and odourants received limited research. Volatile components of two types of CWs prepared from Citrus reticulata Blanco’Chachiensis’ and Camellia sinensis ‘Fudingdabai’ were comprehensively investigated using a combination of stir bar sorptive extraction and gas chromatog.-mass spectrometry (GC-MS). Ninety-nine crucial odourants in the CWs were quantified by applying GC-olfactometry/MS, significant differences were compared, and their odor activity values (OAVs) were calculated Twenty-two odourants (in total 2628.09 and 1131.18 mg/kg resp.) were further confirmed as traditional CW (CW-A) and innovated CW (CW-B) characteristic flavor crucial contributors which all possessed > 1 OAVs, particularly limonene (72919 in CW-A) and trans-β-ionone (138953 in CW-B). The unravelling of CWs aroma composition will greatly expanding our understanding of tea aroma chem. and the potential aroma interactions will offer insights into tea blending technologies. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Synthetic Route of C10H18O2).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C10H18O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tandem catalytic oxidative deacetylation of acetoacetic esters and heteroaromatic cyclizations was written by Ju, Yeming;Miao, Di;Yu, Ruiyang;Koo, Sangho. And the article was included in Organic & Biomolecular Chemistry in 2015.Synthetic Route of C10H13NO2 This article mentions the following:

One pot syntheses of furan, thiophene, and pyrrole were accomplished by oxidative deacetylation using Mn(III)/Co(II) catalysts and the Paal-Knorr reaction from 1,5-dicarbonyl compounds, which are prepared from the conjugate addition of Et acetoacetate to α,β-unsaturated carbonyl compounds The oxidative deacetylation and reductive cyclization of β-ketoesters derived from Et acetoacetate and o-nitrobenzyl bromides efficiently produced diversely substituted indoles. In the experiment, the researchers used many compounds, for example, Ethyl 3-amino-4-methylbenzoate (cas: 41191-92-8Synthetic Route of C10H13NO2).

Ethyl 3-amino-4-methylbenzoate (cas: 41191-92-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C10H13NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Structure-Guided Design of Novel, Potent, and Selective Macrocyclic Plasma Kallikrein Inhibitors was written by Li, Zhe;Partridge, James;Silva-Garcia, Abel;Rademacher, Peter;Betz, Andreas;Xu, Qing;Sham, Hing;Hu, Yunjin;Shan, Yuqing;Liu, Bin;Zhang, Ying;Shi, Haijuan;Xu, Qiong;Ma, Xubo;Zhang, Li. And the article was included in ACS Medicinal Chemistry Letters in 2017.Category: esters-buliding-blocks This article mentions the following:

A series of macrocyclic analogs were designed and synthesized based on the cocrystal structure of small mol. plasma kallikrein (pKal) inhibitor, I, with the pKal protease domain. This led to the discovery of a potent macrocyclic pKal inhibitor II, with an IC₅₀ of 2 nM for one olefinic isomer and 42.3 nM for the other olefinic isomer. In the experiment, the researchers used many compounds, for example, Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1Category: esters-buliding-blocks).

Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effects of cigarette filter design on release behavior of monomer flavor in breakable capsule was written by Gu, Junping;Tao, Hong;Wang, Junxia;Chen, Senlin;Ouyang, Lusi;Lin, Baomin;Lu, Jiajian. And the article was included in Yancao Keji in 2021.HPLC of Formula: 659-70-1 This article mentions the following:

In order to investigate the influences of cigarette filter design on the release of monomer flavor components in breakable capsules, the effects of capsule location in filter and filter ventilation on the transfer rates and puff-by-puff releases of 40 representative monomer flavor components in mainstream cigarette smoke were analyzed. The results showed that: 1) Capsule location in filter and filter ventilation levels significantly affected the transfer rates of the aroma components. The transfer rates of the monomer aroma components were higher when the capsule was planted at 6 mm to the mouth end as compared to those at 18 mm, or when the filter was unventilated. With the increase of the mol. weight of flavor compound, the transfer rate ratios between the capsule planted at 6 mm and that at 18 mm of the same component in alc., ketone and ester homologues presented different variation trends. The transfer rate ratios when the filter was unventilated to that of ventilated of the same component in these homologues deceased. 2) The puff-by-puff releases and the puff-by-puff releases per unit TPM of monomer aroma components were higher when the capsule was planted at 6 mm than at 18 mm. The puff-by-puff releases were higher and the puff-by-puff releases per unit TPM were lower when the filter was unventilated than ventilated. 3) The releases of those aroma components with a lower b.p., such as Et hexanoate, Et heptanoate, 2-heptanone, 2-octanone and 1-pentanol, increased significantly at the fourth and fifth puffs. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1HPLC of Formula: 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.HPLC of Formula: 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Identification of Key Aroma Compounds in Cranberry Juices as Influenced by Vinification was written by Zhang, Jingying;Kilmartin, Paul A.;Peng, Yaoyao;Chen, Xiao;Quek, Siew-Young. And the article was included in Journal of Agricultural and Food Chemistry in 2020.HPLC of Formula: 868-57-5 This article mentions the following:

This study aimed to identify the key aroma-active volatiles in cranberry wines through three vinification methods (White, Red and Thermo) using GC-MS/O to identify the important aroma compounds A total of 70 compounds were detected, with 67 in wines and 61 in juices. The esters was the most diversified class, while alcs. and acids were the most abundant, especially 3-methylbutanol, methylbutyric acid, and benzoic acid. The volatile profiles of cranberry wines are distinctive from their source juices. Most alcs., esters, and acids are fermentation-derived, while terpenes, phenols, aldehydes and ketones are varietal. The Red vinification retained the most varietal volatiles from the must, while the White and Thermo vinifications produced more volatiles during fermentation Thermovinification reduced the yield of benzoic acid and its derivatives after fermentation Olfactory anal. identified 47 aroma-active compounds, among which 41 were considered as the major aroma contributors (Et benzoate had the highest modified detection frequency). In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5HPLC of Formula: 868-57-5).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 868-57-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of Heterobiaryl 4-Aryl Furans through a Base-Promoted Decarboxylative Propargylation/Cycloisomerization Annulation was written by Wang, Sasa;Song, Meimei;Li, Xiuguang;Huang, Yunhong;Zhao, Tingxiang;Wei, Zhuoji;Lan, Yanyun;Tan, Haibo. And the article was included in Organic Letters in 2020.Reference of 13669-10-8 This article mentions the following:

A transition-metal-free synthesis of heterobiaryl 4-aryl furans through a base-promoted decarboxylative propargylation/cycloisomerization annulation of ethynyl benzoxazinanones and readily accessible β-keto esters or 1,3-diketones has been developed. A series of novel heterobiaryl 4-aryl furans were accessed efficiently in the presence of base under mild reaction conditions. This protocol is significant for probing the reaction mechanism of ethynyl benzoxazinanones and even other propargylic compounds In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Reference of 13669-10-8).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Reference of 13669-10-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics