Tag: 100-200

Phytoremediation, eco-restoration, and adaptive response of lemongrass (C. flexuosus Wats) grown on fly ash and vermicompost improved quality essential oil yield was written by Kumar, A.;Jnanesha, A. C.;Verma, R. K.;Kumar, D.;Lal, R. K.. And the article was included in Biochemical Systematics and Ecology in 2022.Recommanded Product: 105-87-3 This article mentions the following:

This study aimed to see how fly ash (FA) and vermicompost (VC) proportions affected lemongrass growth characteristics, essential oil yield, and quality. The application of 10% Fly ash with 90% vermicompost produced considerably greater biomass yield (69.7t/ha) and essential oil yield (429.3 kg/ha) than the rest of the cultivar, followed by 20% FA + 80% VC (68.5 t/ha and 401.2 kg/ha), resp. and 100% VC (68.3 t/ha and 371.0 kg/ha), resp. Citral content, a combination of isomeric aldehydes such as neral and geranial, was used to determine lemongrass oils quality. Geranial and neral concentrations of more than 75% are considered high-grade essential oils. Geranial and neral were our researchs most important essential oil components. All treatments except zero fertilizer, i.e., control, had higher geranial and neral content (%). However, the concentration of geranial and geranyl acetate in lemongrass is unaffected by treatment among these many treatments. 10% FA + 90% VC had greater gross return, the net return, and B: C ratios than the remainder of the treatment, followed by 20% FA + 80% VC and 100% VC. In the meantime, there was no discernible variation in bulk d. (mg m-3) or infiltration rate (cm hr-1). However, a considerable difference was seen concerning porosity, with 100% VC recorded significantly higher porosity (52.8%) than the rest of the treatment. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Recommanded Product: 105-87-3).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Recommanded Product: 105-87-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

DNA base pair-specific ligands. I. Synthesis of distamycin A and its analogs with different numbers of N-methyl-and N-propylpyrrole residues was written by Grokhovskii, S. L.;Zhuze, A. L.;Gottikh, B. P.. And the article was included in Bioorganicheskaya Khimiya in 1975.Reference of 5930-92-7 This article mentions the following:

Distamycin A (I, R = Me) and its structural analogs I (R = Pr), II (R = Me, Pr), and III (R = Me, Pr) were obtained from Et 4-nitropyrrole-2-carboxylate by alkylation, saponification, chlorination, treatment with H2NCH2CH2CN, and hydrogenation. In the experiment, the researchers used many compounds, for example, Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7Reference of 5930-92-7).

Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Reference of 5930-92-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of quaternary carbon-centered benzoindolizidinones via novel photoredox-catalyzed alkene aminoarylation: facile access to tylophorine and analogues was written by Zhang, Chao;Wang, Yi;Song, Yugang;Gao, Hongying;Sun, Yonghui;Sun, Xiuyun;Yang, Yiqing;He, Ming;Yang, Zimo;Zhan, Lingpeng;Yu, Zhi-Xiang;Rao, Yu. And the article was included in CCS Chemistry in 2019.Computed Properties of C6H12O2 This article mentions the following:

Photoredox-catalyzed aminoarylation and thioamination of unactivated alkenes was developed, providing novel synthetic routes to access synthetically challenging quaternary carbon-centered benzoindolizidinones and trifluoromethylthiolated piperidines using readily available starting materials. Notably, these transformations were enabled by merging amidyl radical generation from N-alkyl benzamides with oxidant incorporation. D. functional theory calculations were performed to understand the reaction mechanism and to rationalize the regioselectivities. Moreover, the newly developed catalytic aminoarylation provided a convenient synthetic route for natural product tylophorine and its gem-di-Me analogs with greatly improved drug-like properties such as enhanced solubility and stability. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5Computed Properties of C6H12O2).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Computed Properties of C6H12O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Catalytic, Cascade Ring-Opening Benzannulations of 2,3-Dihydrofuran O,O- and N,O-Acetals was written by Aponte-Guzman, Joel;Phun, Lien H.;Cavitt, Marchello A.;Taylor, J. Evans Jr.;Davy, Jack C.;France, Stefan. And the article was included in Chemistry – A European Journal in 2016.Application In Synthesis of Ethyl 3-oxo-3-(thiophen-2-yl)propanoate This article mentions the following:

An Al(OTf)₃-catalyzed intramol. cascade ring-opening benzannulation of 2,3-dihydrofuran O,O- and N,O-acetals was described. The cascade sequence involved the dihydrofuran ring-opening by acetal hydrolysis, an intramol. Prins-type cyclization, and aromatization to generate an array of benzo-fused (hetero)aromatic systems in up to 95 % yield. This method represented the first example of dihydrofuran acetal usage in benzannulation reactions. The approach provided excellent regiocontrol based on the choice of alkenes used to form the requisite dihydrofuran acetals. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Application In Synthesis of Ethyl 3-oxo-3-(thiophen-2-yl)propanoate).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application In Synthesis of Ethyl 3-oxo-3-(thiophen-2-yl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease was written by Harrison, Justin R.;Sarkar, Sandipan;Hampton, Shahienaz;Riley, Jennifer;Stojanovski, Laste;Sahlberg, Christer;Appelqvist, Pia;Erath, Jessey;Mathan, Vinodhini;Rodriguez, Ana;Kaiser, Marcel;Pacanowska, Dolores Gonzalez;Read, Kevin D.;Johansson, Nils Gunnar;Gilbert, Ian H.. And the article was included in Journal of Medicinal Chemistry in 2020.Product Details of 14667-47-1 This article mentions the following:

Chagas disease is caused by the protozoan parasite Trypanosoma cruzi. It is endemic in South and Central America and recently has been found in other parts of the world, due to migration of chronically infected patients. The current treatment for Chagas disease is not satisfactory, and there is a need for new treatments. In this work, we describe the optimization of a hit compound resulting from the phenotypic screen of a library of compounds against T. cruzi. The compound series was optimized to the level where it had satisfactory pharmacokinetics to allow an efficacy study in a mouse model of Chagas disease. We were able to demonstrate efficacy in this model, although further work is required to improve the potency and selectivity of this series. In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1Product Details of 14667-47-1).

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Product Details of 14667-47-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of lactic acid bacteria for improving the quality of reduced-salt dry fermented sausage: Texture, color, and flavor profiles was written by Hu, Yingying;Li, Yongjie;Li, Xiang-ao;Zhang, Hongwei;Chen, Qian;Kong, Baohua. And the article was included in LWT–Food Science and Technology in 2022.Application of 105-87-3 This article mentions the following:

The traditional dry sausage is highly appreciated in China because of its unique quality characteristics, but it contains high salt content. Hence, this study aimed to evaluate the effects of lactic acid bacteria (LAB) comprising Lactobacillus sakei (LS), Lactobacillus curvatus (LC), Lactobacillus plantarum (LP), and Weissella hellenica (WH) on the quality attributes of the reduced-salt dry fermented sausages. The results indicated that the LP sausage showed higher (P < 0.05) shear force value compared to the other sausages, while the LP, LC, and WH sausages had higher (P < 0.05) lightness values than the control sausages. Seventy-six volatile compounds were detected, and nine compounds were identified as the key differential volatile compounds among the sausages based on partial least squares discriminant anal. Clustering anal. of electronic nose results corresponded well to the volatile compound results. The sensory evaluation confirmed that the inoculation with LC and LP had a pos. impact on the aroma, color, and hardness attributes of the reduced-salt sausages. Besides, partial least squares regression anal. further indicated that L. curvatus and L. plantarum could be used as the potential starter cultures to manufacture reduced-salt dry fermented sausage having improved texture, color, and flavor. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Application of 105-87-3).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 105-87-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rhodium-Catalyzed Intramolecular Silylcarbotricyclization (SiCaT) of Triynes was written by Ojima, Iwao;Vu, An T.;McCullagh, James V.;Kinoshita, Atsushi. And the article was included in Journal of the American Chemical Society in 1999.Quality Control of Diethyl 2-(prop-2-yn-1-yl)malonate This article mentions the following:

Intramol. silylcarbotricyclization of triynes is catalyzed by various Rhodium complexes. For example the triyne HCCCH₂C(CO₂Et)₂CH₂CCCH₂C(CO₂Et)₂CH₂CCH was reacted with PhMe₂SiH in the presence Rh(acac)(CO)₂ to give the cyclization products I, II, and III. A mechanism is proposed for these cyclizations which involves silicon-initiated carbometalation followed by subsequent carbocyclization and β-hydride elimination. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Quality Control of Diethyl 2-(prop-2-yn-1-yl)malonate).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Quality Control of Diethyl 2-(prop-2-yn-1-yl)malonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor α/γ ligand LT175 was written by Piemontese, Luca;Fracchiolla, Giuseppe;Carrieri, Antonio;Parente, Mariagiovanna;Laghezza, Antonio;Carbonara, Giuseppe;Sblano, Sabina;Tauro, Marilena;Gilardi, Federica;Tortorella, Paolo;Lavecchia, Antonio;Crestani, Maurizio;Desvergne, Beatrice;Loiodice, Fulvio. And the article was included in European Journal of Medicinal Chemistry in 2015.Recommanded Product: 15399-05-0 This article mentions the following:

The effects resulting from the introduction of an oxime group in place of the distal aromatic ring of the di-Ph moiety of LT175, previously reported as a PPARα/γ dual agonist, have been investigated. This modification allowed the identification of new bioisosteric ligands with fairly good activity on PPARα and fine-tuned moderate activity on PPARγ. For the most interesting compound (S)-2-[4-(Propoxyimino-methyl)phenoxy]-3-phenylpropanoic acid ((S)-3), docking studies in PPARα and PPARγ provided a mol. explanation for its different behavior as full and partial agonist of the two receptor isotypes, resp. A further investigation of this compound was carried out performing gene expression studies on HepaRG cells. The results obtained allowed to hypothesize a possible mechanism through which this ligand could be useful in the treatment of metabolic disorders. The higher induction of the expression of some genes, compared to selective agonists, seems to confirm the importance of a dual PPARα/γ activity which probably involves a synergistic effect on both receptor subtypes. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Recommanded Product: 15399-05-0).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 15399-05-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

3D-QSAR-Assisted Drug Design: Identification of a Potent Quinazoline-Based Aurora Kinase Inhibitor was written by Ke, Yi-Yu;Shiao, Hui-Yi;Hsu, Yung Chang;Chu, Chang-Ying;Wang, Wen-Chieh;Lee, Yen-Chun;Lin, Wen-Hsing;Chen, Chun-Hwa;Hsu, John T. A.;Chang, Chun-Wei;Lin, Cheng-Wei;Yeh, Teng-Kuang;Chao, Yu-Sheng;Coumar, Mohane Selvaraj;Hsieh, Hsing-Pang. And the article was included in ChemMedChem in 2013.Application of 16413-26-6 This article mentions the following:

We describe the 3D-QSAR-assisted design of an Aurora kinase A inhibitor with improved physicochem. properties, in vitro activity, and in vivo pharmacokinetic profiles over those of the initial lead. Three different 3D-QSAR models were built and validated by using a set of 66 pyrazole (Model I) and furanopyrimidine (Model II) compounds with IC₅₀ values toward Aurora kinase A ranging from 33 nM to 10.5 μM. The best 3D-QSAR model, Model III, constructed with 24 training set compounds from both series, showed robustness (r²_CV=0.54 and 0.52 for CoMFA and CoMSIA, resp.) and superior predictive capacity for 42 test set compounds (R²_pred=0.52 and 0.67, CoMFA and CoMSIA). Superimposition of CoMFA and CoMSIA Model III over the crystal structure of Aurora kinase A suggests the potential to improve the activity of the ligands by decreasing the steric clash with Val147 and Leu139 and by increasing hydrophobic contact with Leu139 and Gly216 residues in the solvent-exposed region of the enzyme. Based on these suggestions, the rational redesign of furanopyrimidine 24 (clog P=7.41; Aurora A IC₅₀=43 nM; HCT-116 IC₅₀=400 nM) led to the identification of quinazoline 67 (clog P=5.28; Aurora A IC₅₀=25 nM; HCT-116 IC₅₀=23 nM). Rat in vivo pharmacokinetic studies showed that 67 has better systemic exposure after i.v. administration than 24, and holds potential for further development. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Application of 16413-26-6).

3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 16413-26-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Delineating the extra-virgin olive oil aroma blueprint by multiple headspace solid phase microextraction and differential-flow modulated comprehensive two-dimensional gas chromatography was written by Stilo, Federico;Segura Borrego, Maria del Pilar;Bicchi, Carlo;Battaglino, Sonia;Callejon Fernadez, Raquel Maria;Morales, Maria Lourdes;Reichenbach, Stephen E.;Mccurry, James;Peroni, Daniela;Cordero, Chiara. And the article was included in Journal of Chromatography A in 2021.Related Products of 695-06-7 This article mentions the following:

Comprehensive two-dimensional gas chromatog. with parallel mass spectrometry and flame ionization detection (GC x GC-MS/FID) enables effective chromatog. fingerprinting of complex samples by comprehensively mapping untargeted and targeted components. Moreover, the complementary characteristics of MS and FID open the possibility of performing multi-target quant. profiling with great accuracy. If this synergy is applied to the complex volatile fraction of food, sample preparation is crucial and requires appropriate methodologies capable of providing true quant. results. In this study, untargeted/targeted (UT) fingerprinting of extra-virgin olive oil volatile fractions is combined with accurate quant. profiling by multiple headspace solid phase microextraction (MHS-SPME). External calibration on fifteen pre-selected analytes and FID predicted relative response factors (RRFs) enable the accurate quantification of forty-two analytes in total, including key-aroma compounds, potent odorants, and olive oil geog. markers. Results confirm good performances of comprehensive UT fingerprinting in developing classification models for geog. origin discrimination, while quantification by MHS-SPME provides accurate results and guarantees data referability and results transferability over years. Moreover, by this approach the extent of internal standardization procedure inaccuracy, largely adopted in food volatiles profiling, is measured. Internal standardization yielded an average relative error of 208% for the fifteen calibrated compounds, with an overestimation of + 538% for (E)-2-hexenal, the most abundant yet informative volatile of olive oil, and a -89% and -80% for (E)-2-octenal and (E)-2-nonenal resp., analytes with a lower HS distribution constant Compared to existing methods based on 1D-GC, the current procedure offers better separation power and chromatog. resolution that greatly improve method specificity and selectivity and results in lower LODs and LOQs, high calibration performances (i.e., R2 and residual distribution), and wider linear range of responses. As an artificial intelligence smelling machine, the MHS-SPME-GC x GC-MS/FID method is here adopted to delineate extra-virgin olive oil aroma blueprints; an objective tool with great flexibility and reliability that can improve the quality and information power of each anal. run. In the experiment, the researchers used many compounds, for example, 5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7Related Products of 695-06-7).

5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 695-06-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics