Tag: 100-200

The author of 《Cp*CoIII-catalyzed formal [4+2] cycloaddition of benzamides to afford quinazolinone derivatives》 were Yang, Jingshu; Hu, Xiao; Liu, Zijie; Li, Xueyuan; Dong, Yi; Liu, Gang. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Computed Properties of C9H8O4 The author mentioned the following in the article:

A Cp*CoIII-catalyzed arene C-H bond amidation/annulation of benzamides was developed to afford quinazolinone derivatives in one-pot with high yields and broad substrate scope. This method could be applied to the synthesis of quinazolinone drugs and late-stage modification of natural products. The experimental process involved the reaction of 3-(Methoxycarbonyl)benzoic acid(cas: 1877-71-0Computed Properties of C9H8O4)

3-(Methoxycarbonyl)benzoic acid(cas: 1877-71-0) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Computed Properties of C9H8O4 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2021,Phosphorus, Sulfur and Silicon and the Related Elements included an article by Yu, Zhiqun; Yao, Hongmiao; Xu, Qilin; Liu, Jiming; Le, Xingmao; Ren, Minna. Computed Properties of C7H13NO2. The article was titled 《Bronsted acid-catalyzed chlorination of aromatic carboxylic acids》. The information in the text is summarized as follows:

The chlorination of aromatic carboxylic acids with SOCl2 has been effectively performed by reacting with a Bronsted acid as the catalyst. Based on this discovery, an efficient catalytic method that is cheaper than traditional catalytic methods was developed. 20 substrates were chlorinated offering excellent yields in a short reaction time. And the SOCl2/Bronsted acid system has been used in a larger scale preparative reaction. A dual activation mechanism was proposed to prove the irreplaceable system of SOCl2/Bronsted acid. The experimental part of the paper was very detailed, including the reaction process of Ethyl 3-(dimethylamino)acrylate(cas: 924-99-2Computed Properties of C7H13NO2)

Ethyl 3-(dimethylamino)acrylate(cas: 924-99-2) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).Computed Properties of C7H13NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: Methyl 3-hydroxypropanoateIn 2009 ,《Theoretical study on the thermolysis of methyl 3-hydroxypropanoate in m-xylene solution》 was published in Journal of Molecular Structure: THEOCHEM. The article was written by Rodriguez-Linares, Diana; Codorniu-Hernandez, Edelsys; Velez-Ortiz, Ederley; Murillo-Lopez, Juliana-Andrea; Villegas-Bolanos, Paola-Andrea; Quijano-Tobon, Jairo. The article contains the following contents:

Solvent effects on the thermolysis of Me 3-hydroxypropanoate in m-xylene were studied through the SCIPCM model (MP2/6-31G(d)) and the Multiple Min. Hypersurfaces Procedure (MMH). Important information about the kinetic and thermodn. behavior of the reaction is provided by the combination of explicit and implicit models. Quantum mech. optimizations and statistical thermodn. of MMH allow to obtain thermodn. magnitudes of the reaction in solution The optimum configurations for solute-solvent associations with the explicit addition of m-xylene mols. are provided. MMH could be used as a fast and reliable way for the prediction of a reaction in certain media and addnl. information about the solute-solvent intermol. association can be obtained. After reading the article, we found that the author used Methyl 3-hydroxypropanoate(cas: 6149-41-3Recommanded Product: Methyl 3-hydroxypropanoate)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: Methyl 3-hydroxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Category: esters-buliding-blocksIn 2021 ,《A supramolecular double-helix based on complementary phosphate-guanidinium pairing》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Thiele, Maike; Octa-Smolin, Frescilia; Thoelke, Simon; Woelper, Christoph; Linders, Juergen; Mayer, Christian; Haberhauer, Gebhard; Niemeyer, Jochen. The article contains the following contents:

A double-helical supramol. structure was formed by self-assembly of 1,1′;-binaphthyl-based bisguanidines and bisphosphoric acids. Interestingly the homochiral (S,S) + (S,S)-pair forms a left-handed double-helix, while the heterochiral (S,S) + (R,R)-pair forms a non-helical dimer. The results came from multiple reactions, including the reaction of tert-Butyl carbamate(cas: 4248-19-5Category: esters-buliding-blocks)

tert-Butyl carbamate(cas: 4248-19-5) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,Wang, Wen-Tao; Zhang, Sen; Tao, Ling-Fei; Pan, Zi-Qi; Qian, Linghui; Liao, Jia-Yu published an article in Chemical Communications (Cambridge, United Kingdom). The title of the article was 《Cooperative catalysis-enabled C-N bond cleavage of biaryl lactams with activated isocyanides》.Computed Properties of C5H11NO2 The author mentioned the following in the article:

The catalytic reaction of biaryl lactams with activated isocyanides was reported for the first time. By employing a cooperative catalytic system, oxazole-containing axially chiral biaryl anilines, e.g., I were obtained in high yields with excellent enantioselectivities. The key to the success was in the atroposelective amide C-N bond cleavage with activated isocyanides. In the experiment, the researchers used tert-Butyl carbamate(cas: 4248-19-5Computed Properties of C5H11NO2)

tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Computed Properties of C5H11NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,Wang, Guangzhu; Shen, Chaoren; Ren, Xinyi; Dong, Kaiwu published an article in Chemical Communications (Cambridge, United Kingdom). The title of the article was 《Ni-Catalyzed enantioselective reductive arylcyanation/cyclization of N-(2-iodo-aryl) acrylamide》.Application In Synthesis of Diethyl 2-methylmalonate The author mentioned the following in the article:

A Ni/(S,S)-BDPP-catalyzed intramol. Heck cyclization of N-(2-iodo-aryl)acrylamides with 2-methyl-2-phenylmalononitrile was developed to give oxindoles with good enantioselectivities. By utilizing such an electrophilic cyanation reagent could tackle the deleterious effect of the coordinative cyanide ion in the asym. alkene arylcyanation. The experimental part of the paper was very detailed, including the reaction process of Diethyl 2-methylmalonate(cas: 609-08-5Application In Synthesis of Diethyl 2-methylmalonate)

Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Application In Synthesis of Diethyl 2-methylmalonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,Feng, Minghao; Madegard, Lea; Riomet, Margaux; Louis, Manon; Champagne, Pier Alexandre; Pieters, Gregory; Audisio, Davide; Taran, Frederic published an article in Chemical Communications (Cambridge, United Kingdom). The title of the article was 《Selective chlorination of iminosydnones for fast release of amide, sulfonamide and urea-containing drugs》.Computed Properties of C5H11NO2 The author mentioned the following in the article:

Herein, a methodol. for iminosydnone chlorination is described, and the high beneficial effect of this modification on the reactivity of these mesoionic dipoles in strain-promoted cycloaddition reactions is demonstrated. These new iminosydnones were used in reactions with azacyclooctyne for bioorthogonal release of amide, urea and sulfonamide containing drugs. Notably, drugs containing a terminal amide function were released for the first time with good kinetic constants In addition to this study using tert-Butyl carbamate, there are many other studies that have used tert-Butyl carbamate(cas: 4248-19-5Computed Properties of C5H11NO2) was used in this study.

tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. To avoid the problem of multiple alkylation, methods have been devised for “blocking” substitution so that only one alkyl group is introduced. The Gabriel synthesis is one such method; it utilizes phthalimide, C6H4(CO)2NH, whose one acidic hydrogen atom has been removed upon the addition of a base such as KOH to form a salt.Computed Properties of C5H11NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sun, Zhongwen; Chen, Lijun; Qiu, Kaixiong; Liu, Bo; Li, Hongtao; Yu, Fang published an article in 2022. The article was titled 《Enantioselective Peroxidation of C-alkynyl imines enabled by chiral BINOL calcium phosphate》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Formula: C5H11NO2 The information in the text is summarized as follows:

Herein, a catalytic enantioselective addition of C-alkynyl imines, generated in-situ from N,O-acetals R1CCCH(OEt)NHR2 (R1 = Me3Si, Ph, 2-ClC6H4, 1-naphthyl, 2-thienyl, 3-pyridinyl, etc., R2 = Boc; R1 = Ph, R2 = Teoc, PhCO, Fmoc, Cbz) with hydroperoxides R3OOH (R3 = t-Bu, PhCH2, EtMe2, etc.) catalyzed by chiral BINOL calcium phosphate, affording a broad range of enantioenriched α-peroxy propargylamines (R)-R1CCCH(OOR3)NHR2 in good yields (80-99%) with high enantioselectivities (up to 94% ee) is reported. The protocol is characterized by mild conditions, easy accessibility and good practicability. In the experiment, the researchers used many compounds, for example, tert-Butyl carbamate(cas: 4248-19-5Formula: C5H11NO2)

tert-Butyl carbamate(cas: 4248-19-5) belongs to anime. Left-handed and right-handed forms (mirror-image configurations, known as optical isomers or enantiomers) are possible when all the substituents on the central nitrogen atom are different (i.e., the nitrogen is chiral). With amines, there is extremely rapid inversion in which the two configurations are interconverted.Formula: C5H11NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Supramolecularly regulated copper-bisoxazoline catalysts for the efficient insertion of carbenoid species into hydroxyl bonds》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Iniesta, Ester; Vidal-Ferran, Anton. Recommanded Product: 609-14-3 The article mentions the following:

The catalytic insertion of copper carbenoids into O-H bonds affords synthetically useful α-alkyl/aryl-α-alkoxy/aryloxy derivatives Herein, the design, preparation and application of supramolecularly regulated copper(I) complexes of bisoxazoline ligands is reported. The catalytic performance of these systems can be modulated using an external mol. (i.e. the regulation agent), which interacts with a polyethyleneoxy chain on the ligand (i.e. the regulation site) via supramol. interactions. This approach was applied to an array of structurally diverse alcs. (cycloalkyl, alkyl and aryl derivatives). Moreover, the authors used this methodol. to synthesize advanced synthetic intermediates of biol. relevant compoundsEthyl 2-methyl-3-oxobutanoate(cas: 609-14-3Recommanded Product: 609-14-3) was used in this study.

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Recommanded Product: 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Chiral stimuli-responsive metallo-supramolecular assembly induced by CuII/CuI redox change》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Marinova, Maya; Bonnefont, Antoine; Achard, Thierry; Maisse-Francois, Aline; Bellemin-Laponnaz, Stephane. Synthetic Route of C8H14O4 The article mentions the following:

Authors investigated the selective formation of homoleptic and heteroleptic metal complexes controlled by the chiral mol. instruction of the ligand and the coordination geometry of the metal. The results showed that chiral self-recognition or self-discrimination may be induced by the CuI/CuII redox transition using cyclic voltammetry. The further use of chiral ditopic ligands led to metallo-supramol. copolymers with stimuli-responsive controlled arrangement. In the experiment, the researchers used many compounds, for example, Diethyl 2-methylmalonate(cas: 609-08-5Synthetic Route of C8H14O4)

Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Synthetic Route of C8H14O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics