Tag: 100-200

Baal, Eduard; Klein, Marius; Harms, Klaus; Sundermeyer, Jorg published an article in 2021. The article was titled 《2,9-Diazadibenzoperylene and 2,9-Dimethyldibenzoperylene-1,3,8,10-tetratriflates: Key to Functionalized 2,9-Diazaperopyrenes》, and you may find the article in Chemistry – A European Journal.Reference of Diethyl 2-methylmalonate The information in the text is summarized as follows:

The synthesis of 2,9-diaza-1,3,8,10-tetratriflato-dibenzoperylene and corresponding 2,9-dimethyl-1,3,8,10-tetratriflato-dibenzoperylene I [X = NH, CMe] was developed at multigram scale via reduction of one of industrially most important high-performance dyes, perylene-3,4,9,10-tetracarboxylic diimide (PTCDI) and of corresponding dihydroxy peropyrenequinone precursor. The focus of this paper was on reactivity pattern of compound I [X = NH] as key intermediate toward highly functionalized 2,9-diazadibenzopyrelenes (DDPs) II [R = 2-thienyl, C≡CSiMe3, piperidinyl, etc.] obtained via catalytic substitution of four triflate by aryl, heteroaryl, alkynyl, aminyl, and O-phosphanyl substituents. The influence of electron-donating substituents (OSiMe3, OPt-Bu2, N-piperidinyl), electron-withdrawing (OTf, 3,5-bis-trifluoromethyl-phenyl) and of electron-rich π-conjugated (2-thienyl, 4-tert-butylphenyl, trimethylsilyl-ethynyl) substituents on optoelectronic and structural properties of these functionalized DDPs II was investigated via XRD analyzes, UV/Vis, PL spectroscopy, and by electroanal. CV. These results were correlated to results of DFT and TD-DFT calculations Thus, functionalized DPPs II with easily tunable HOMO and LUMO energies and gap became available via a new and reliable synthetic strategy starting from readily available PTCDI. In the experiment, the researchers used Diethyl 2-methylmalonate(cas: 609-08-5Reference of Diethyl 2-methylmalonate)

Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Reference of Diethyl 2-methylmalonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kaur, Ravneet; Singh, Dipak; Singh, Ravi P. published their research in Journal of Organic Chemistry in 2021. The article was titled 《Stereoselective Synthesis of Dihydrocoumarins via [1,2]-Phospha-Brook Rearrangement in Three-Component Coupling Reaction of α-Ketoesters, o-Quinone Methides, and Dialkyl Phosphites》.Product Details of 4755-77-5 The article contains the following contents:

A highly regio- and diastereoselective approach for the synthesis of phosphate substituted dihydrocoumarins I (R1 = 4-methoxyphenyl, 2-(4-methylphenyl)ethenyl, 2-phenylethenyl, etc.; R2 = Ph, 3-bromophenyl, 2-thienyl, etc.; R3 = i-Pr, Et, Ph) via Bronsted base catalyzed [1,2]-phospha-Brook rearrangement is reported. The two-step, one-pot Michael addition of α-phosphonyloxy enolates proceeds by coupling of dialkyl phosphite HP(=O)(OR3)2 and α-ketoesters R2C(O)C(O)OEt to o-quinone methides II, followed by an intramol. cyclization, providing 3,4-dihydrocoumarin frameworks I. The results came from multiple reactions, including the reaction of Ethyl oxalyl monochloride(cas: 4755-77-5Product Details of 4755-77-5)

Ethyl oxalyl monochloride(cas: 4755-77-5) belongs to acyl chlorides. In the laboratory, acyl chlorides are generally prepared by treating carboxylic acids with thionyl chloride (SOCl2). The reaction is catalyzed by dimethylformamide and other additives.Product Details of 4755-77-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bettoni, Leo; Joly, Nicolas; Lohier, Jean-Francois; Gaillard, Sylvain; Poater, Albert; Renaud, Jean-Luc published their research in Advanced Synthesis & Catalysis in 2021. The article was titled 《Ruthenium-Catalyzed Three-Component Alkylation: A Tandem Approach to the Synthesis of Nonsymmetric N,N-Dialkyl Acyl Hydrazides with Alcohols》.Recommanded Product: Methyl 4-fluorobenzoate The article contains the following contents:

The borrowing hydrogen strategy has been applied in the synthesis of nonsym. N,N-dialkylated acyl hydrazides via a tandem three-component reaction catalyzed by a phosphine free diaminocyclopentadienone ruthenium tricarbonyl complex. This strategy represents the first direct one-pot approach to nonsym. functionalized acyl hydrazides. Different aromatic acyl hydrazides underwent dialkylation with a variety of primary or secondary alcs. and methanol or ethanol as alkylating agents in mild reaction conditions and good yields. Deuterium labeling experiments suggested that the primary or secondary alc. was the hydrogen source in this tandem process. DFT calculations show that the combination of the tandem mixed product cannot be perfectly explained neither structurally nor electronically, but might be dependent of the phys. state of the aldehyde or ketone intermediate (gaz vs. liquid) at the reaction temperatureMethyl 4-fluorobenzoate(cas: 403-33-8Recommanded Product: Methyl 4-fluorobenzoate) was used in this study.

Methyl 4-fluorobenzoate(cas: 403-33-8) is an organic fluorinated building block used for the synthesis of various pharmaceutical compounds. It can be used for the preparation of Blonanserin.Recommanded Product: Methyl 4-fluorobenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Direct Construction of NOBINs via Domino Arylation and Sigmatropic Rearrangement Reactions》 was published in Chinese Journal of Chemistry in 2020. These research results belong to Zhang, Ji-Wei; Qi, Liang-Wen; Li, Shaoyu; Xiang, Shao-Hua; Tan, Bin. Name: N-tert-Butoxycarbonylhydroxylamine The article mentions the following:

Privileged 2-amino-2′-hydroxy-1,1′-binaphthyl (NOBIN) frameworks were constructed through a novel domino arylation of naphthylhydroxylamines with diarylhalonium salts and sigmatropic rearrangement in a transition metal-free fashion. This protocol bears broad substrate generality and proceeded under mild reaction conditions, affording diversified NOBINs in high efficiency with absolute regiocontrol during the rearrangement process. Optically active product was accessible by chiral N-heterocyclic carbene-catalyzed kinetic resolution in one pot or diastereoselective [3,3]-rearrangement guided by a removable chiral auxiliary. Remarkably, diarylchloronium and diarylbrominium salts were employed as arylation reagents for the first time in assembling such representative biaryl frameworks.N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3Name: N-tert-Butoxycarbonylhydroxylamine) was used in this study.

N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3) belongs to anime. Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Naturally occurring amines include the alkaloids, which are present in certain plants; the catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a local chemical mediator, histamine, that occurs in most animal tissues.Name: N-tert-Butoxycarbonylhydroxylamine

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Compression-responsive photonic crystals based on fluorine-containing polymers》 were Kredel, Julia; Gallei, Markus. And the article was published in Polymers (Basel, Switzerland) in 2019. Application In Synthesis of Benzyl acrylate The author mentioned the following in the article:

Fluoropolymers represent a unique class of functional polymers due to their various interesting and important properties such as thermal stability, resistance toward chems., repellent behaviors, and their low refractive indexes in comparison to other polymeric materials. Based on the latter optical property, fluoropolymers are particularly of interest for the preparation of photonic crystals for optical sensing application. Within the present study, photonic crystals were prepared based on core-interlayer-shell particles focusing on fluoropolymers. For particle assembly, the melt-shear organization technique was applied. The high order and refractive index contrast of the individual components of the colloidal crystal structure lead to remarkable reflection colors according to Bragg’s law of diffraction. Due to the special architecture of the particles, consisting of a soft core, a comparably hard interlayer, and again a soft shell, the resulting opal films were capable of changing their shape and domain sizes upon applied pressure, which was accompanied with a (reversible) change of the observed reflection colors as well. By the incorporation of adjustable amounts of UV crosslinking agents into the opal film and subsequent treatment with different UV irradiation times, stable and pressure-sensitive opal films were obtained. It is shown that the present strategy led to (i) pressure-sensitive opal films featuring reversibly switchable reflection colors and (ii) that opal films can be prepared, for which the written pattern-resulting from the compressed particles-could be fixed upon subsequent irradiation with UV light. The herein described novel fluoropolymer-containing photonic crystals, with their pressure-tunable reflection color, are promising candidates in the field of sensing devices and as potential candidates for anti-counterfeiting materials. The experimental part of the paper was very detailed, including the reaction process of Benzyl acrylate(cas: 2495-35-4Application In Synthesis of Benzyl acrylate)

Benzyl acrylate(cas: 2495-35-4) is a reagent that can be used in the preparation of 2-(Phosphonomethyl)pentanedioic Acid, a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor. It can also be used in the preparation of high refractive index polyacrylates.Application In Synthesis of Benzyl acrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Palladium-Catalyzed Synthesis of Indolines from Aroyloxycarbamates through a Tandem Decarboxylative Amination/Heck/Annulation Reaction》 were Wang, Zheng; Li, Peihe; Fu, Hui; Dai, Qipu; Hu, Changwen. And the article was published in Advanced Synthesis & Catalysis in 2019. Product Details of 36016-38-3 The author mentioned the following in the article:

A novel synthesis of functionalized indolines via a Pd-catalyzed tandem decarboxylative amination/Heck/annulation reaction has been developed. This process features operational simplicity, mild conditions, and the use of a readily available and environmentally friendly starting material, namely carboxylic acid. Furthermore, the reaction shows good functional group tolerance and chem. selectivity.N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3Product Details of 36016-38-3) was used in this study.

N-tert-Butoxycarbonylhydroxylamine(cas: 36016-38-3) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Product Details of 36016-38-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Fully Printed Organic Electrochemical Transistors from Green Solvents》 were Schmatz, Brian; Lang, Augustus W.; Reynolds, John R.. And the article was published in Advanced Functional Materials in 2019. Quality Control of Diethyl 2-methylmalonate The author mentioned the following in the article:

To achieve the full potential of scalable and cost-effective organic electronic devices, developments are being made in both academic and industry environments to move toward continuous solution-processing techniques that make use of safe and environmentally benign “”green”” solvents. In this work, the first example of a transistor device that is fully solution processed using only green solvents is demonstrated. This achievement is enabled through a novel multistage cleavable side chain process that provides aqueous solubility for semiconducting conjugated polymers, paired with aqueous inkjet printing of PEDOT:PSS electrodes, and a solution deposited ion gel electrolyte as the dielec. layer. The resulting organic electrochem. transistor devices operate in accumulation mode and reach maximum transconductance values of 1.1 mS at a gate voltage of – 1 V. Normalizing the transconductance value to the channel dimensions yields gm/W = 2200 S m-1 (μC* = 22 F cm-1 V-1 s-1), making these devices suitable for a range of applications requiring small signal amplification such as transistors, biosensors, and ion pumps. This new material design and device process paves the way toward scalable, safe, and efficient production of organic electronic devices. In the experiment, the researchers used many compounds, for example, Diethyl 2-methylmalonate(cas: 609-08-5Quality Control of Diethyl 2-methylmalonate)

Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Quality Control of Diethyl 2-methylmalonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2017,Rajendiran, Senkuttuvan; Park, Kwangho; Lee, Kwangyeol; Yoon, Sungho published 《Ionic-Liquid-Based Heterogeneous Covalent Triazine Framework Cobalt Catalyst for the Direct Synthesis of Methyl 3-Hydroxybutyrate from Propylene Oxide》.Inorganic Chemistry published the findings.Computed Properties of C4H8O3 The information in the text is summarized as follows:

β-Hydroxy esters are considered as potential building blocks for the production of fine chems. and potential drug mols. in various industries. Developing an efficient and recyclable catalyst for the synthesis of β-hydroxy esters is challenging. Here we report the first ionic-liquid-based heterogenized cobalt catalyst, [imidazolium-CTF][Co(CO)4], for the direct ring-opening carbonylation of propylene oxide to Me 3-hydroxybutyrate (MHB) with 86% selectivity (>99% conversion). In addition to this study using Methyl 3-hydroxypropanoate, there are many other studies that have used Methyl 3-hydroxypropanoate(cas: 6149-41-3Computed Properties of C4H8O3) was used in this study.

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Computed Properties of C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2006,Kim, Hoon Sik; Bae, Jin Yong; Lee, Je Seung; Jeong, Cheong Il; Choi, Dae Ki; Kang, Sang Ook; Cheong, Minserk published 《An efficient catalytic system for the carbomethoxylation of ethylene oxide》.Applied Catalysis, A: General published the findings.Synthetic Route of C4H8O3 The information in the text is summarized as follows:

Me β-hydroxypropionate (MHP), an intermediate to propane-1,3-diol (PDO) was produced in high yield from the carbomethoxylation of ethylene oxide (EO) using a catalytic system consisting of Co2(CO)8 and ZnX2L2 (1: L = pyridine; 2: L = phosphine; X = Cl, Br, I). The carbomethoxylation was greatly influenced by the variation of temperature and CO pressure. The increase of temperature increased the EO conversion, but decreased the selectivity to MHP. Both the yield and the selectivity of MHP increased with increasing CO pressure. FT-IR spectroscopic studies show that Co2(CO)8 interacts with (C5H5N)2ZnBr2, affording a new ionic cobalt carbonyl species. After reading the article, we found that the author used Methyl 3-hydroxypropanoate(cas: 6149-41-3Synthetic Route of C4H8O3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Synthetic Route of C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Related Products of 30414-53-0On March 1, 2019, Huang, Wenbo; Xu, Jing; Liu, Changhui; Chen, Zhiyan; Gu, Yanlong published an article in Journal of Organic Chemistry. The article was 《Lewis Acid-Catalyzed Synthesis of Benzofurans and 4,5,6,7-Tetrahydrobenzofurans from Acrolein Dimer and 1,3-Dicarbonyl Compounds》. The article mentions the following:

2,3-Disubstituted benzofurans such as benzofurandicarboxylate I were prepared by cyclocondensation of acrolein dimer (2H-3,4-dihydro-2-pyrancarboxaldehyde) and 1,3-dicarbonyl compounds, particularly β-ketoesters and 1,3-diketones, in the presence of Lewis acid catalysts [either AlCl3 or Sc(OTf)3 or in one case, BF3·Et2O] using N-bromosuccinimide (NBS) as an oxidant. The method was used to prepare benzbromarone and amiodarone. An oxobutylfurancarboxylate intermediate in the cyclocondensation of acrolein dimer and Me acetoacetate was isolated; cyclocondensation with indoles, 1,2,4-trimethoxybenzene, and 1,1-diphenylethylene yielded aryl- and diphenylvinyl-substituted tetrahydrobenzofurancarboxylates such as II [R = 3-indolyl, 1-methyl-3-indolyl, 2,4,5-(MeO)3C6H2, Ph2C:CH]. The experimental part of the paper was very detailed, including the reaction process of Methyl 3-oxovalerate(cas: 30414-53-0Related Products of 30414-53-0)

Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.Related Products of 30414-53-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics