Tag: 100-200

On June 30, 2019, Miltojevic, Ana B.; Stojanovic, Nikola M.; Randjelovic, Pavle J.; Radulovic, Niko S. published an article.COA of Formula: C9H11NO2 The title of the article was Distribution of methyl and isopropyl N-methylanthranilates and their metabolites in organs of rats treated with these two essential-oil constituents. And the article contained the following:

Two volatile alkaloids, Me (MMA) and iso-Pr N-methylanthranilates (IMA), identified in the essential oil of Choisya ternata Kunth (Rutaceae), have been proven to possess polypharmacol. properties (antinociceptive, anti-inflammatory, gastro-, hepato-, nephroprotective activities, anxiolytic and antidepressant properties, and likewise an effect on diazepam-induced sleep). In the continuation of our investigation of their urinary-metabolite profiles, we performed GC-MS analyses of the diethyl-ether extracts of selected tissues (liver, kidneys, heart, brain, lungs, quadriceps femoris muscle, and spleen) of rats i.p. treated with MMA or IMA (2 g kg-1). Organ-metabolite profiles of MMA and IMA were qual. mutually analogous (varying only in the alc. moiety of the metabolites), and generally analogous to their urinary-metabolite profiles. The principal anthranilate-related compounds in the organs of rats treated with MMA, among 12 detected, were the products of ester hydrolysis, N-methylanthranilic and anthranilic acids. In the tissues of IMA-treated rats, among 16 compounds, the most abundant ones were the unmetabolized IMA and N-methylanthranilic acid. A collection of the compositional data regarding the anthranilate-related metabolites was statistically treated by multivariate statistical anal. that provided a better insight into the possible biotransformation pathways. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).COA of Formula: C9H11NO2

The Article related to choisya essential oil methyl isopropyl n methylanthranilate organ distribution, isopropyl n-methylanthranilate, metabolite identification, methyl n-methylanthranilate, multivariate statistical analysis, organs distribution, xenobiotic and other aspects.COA of Formula: C9H11NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bao, Deng-Hui; Wu, Hui-Ling; Liu, Chao-Lun; Xie, Jian-Hua; Zhou, Qi-Lin published an article in 2015, the title of the article was Development of Chiral Spiro P-N-S Ligands for Iridium-Catalyzed Asymmetric Hydrogenation of β-Alkyl-β-Ketoesters.Electric Literature of 3976-69-0 And the article contains the following content:

The chiral tridentate spiro P-N-S ligands, e.g., I, (SpiroSAP) were developed, and their iridium complexes were prepared Introduction of a 1,3-dithiane moiety into the ligand resulted in a highly efficient chiral iridium catalyst for asym. hydrogenation of β-alkyl-β-ketoesters, producing chiral β-alkyl-β-hydroxyesters, e.g., II, with excellent enantioselectivities (95-99.9 % ee) and turnover numbers of up to 355000. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Electric Literature of 3976-69-0

The Article related to tridentate spiro ligand preparation iridium complexation, enantioselective alkyl hydroxyester preparation, alkyl ketoester asym hydrogenation iridium catalyst, asymmetric catalysis, hydrogenation, iridium, ketoesters, spiro ligands and other aspects.Electric Literature of 3976-69-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 17, 2014, Hodgson, David M.; Man, Stanislav; Powell, Kimberley J.; Perko, Ziga; Zeng, Minxiang; Moreno-Clavijo, Elena; Thompson, Amber L.; Moore, Michael D. published an article.Recommanded Product: (Trimethoxymethyl)benzene The title of the article was Intramolecular Oxonium Ylide Formation-[2,3] Sigmatropic Rearrangement of Diazocarbonyl-Substituted Cyclic Unsaturated Acetals: A Formal Synthesis of Hyperolactone C. And the article contained the following:

Rh(II)-catalyzed oxonium ylide formation-[2,3] sigmatropic rearrangement of α-diazo-β-ketoesters possessing γ-cyclic unsaturated acetal substitution, followed by acid-catalyzed elimination-lactonization, provides a concise approach to 1,7-dioxaspiro[4.4]non-2-ene-4,6-diones (e.g., I → II → III). The process creates adjacent quaternary stereocenters with full control of the relative stereochem. An unsym. monomethylated cyclic unsaturated acetal leads to hyperolactone C (IV), where ylide formation-rearrangement proceeds with high selectivity between subtly nonequivalent acetal oxygen atoms. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Recommanded Product: (Trimethoxymethyl)benzene

The Article related to hyperolactone c formal synthesis, diazo carbonyl cyclic unsaturated acetal intramol oxonium ylide formation, sigmatropic rearrangement oxonium ylide formation diazocarbonyl cyclic unsaturated acetal, oxaspirononenedione preparation and other aspects.Recommanded Product: (Trimethoxymethyl)benzene

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 31, 2020, Zhao, Chi; Su, Wei; Mu, Yingchun; Jiang, Li; Mu, Yu published an article.Safety of Diethyl succinate The title of the article was Correlations between microbiota with physicochemical properties and volatile flavor components in black glutinous rice wine fermentation. And the article contained the following:

Black glutinous rice wine (BGRW) is a popular traditional Chinese rice wine; however, the flavors profiles associated with microbiota changes during its fermentation have not yet been evaluated. In this study, we explored the correlations between microbial communities with physicochem. properties and flavor components during BGRW fermentation High-throughput sequencing was used to identify the microbial community composition of BGRW at different fermentation stages, and physicochem. properties and volatile flavor compounds (VFCs) were identified via fermentation features testing and headspace solid phase microextraction gas chromatog. mass spectrometry. First, we revealed Pantoea and Kosakonia predominated bacterial genera the early stage of BGRW fermentation, Leuconostoc, Pediococcus, Bacillus, and Lactobacillus predominated bacterial genera the later stage, while Rhizopus and Saccharomyces were the predominant fungal genera throughout fermentation Second, total sugars, titratable acids, pH, ethanol, amino acid nitrogen, and 43 VFCs were detected during fermentation Twenty-three VFCs were differentially produced according to the linear discriminant anal. effect size method. With the increase of the fermentation time, the kinds and contents of esters and alcs. were also increased, while acids decreased. Moreover, 12 microbial genera, Lactococcus, Pediococcus, Leuconostoc, Lactobacillus, Cronobacter, Pantoea, Weissella, Enterococcus, Rhizopus, Myceliophthora, Cystofilobasidium, and Aspergillus were found to be highly correlated (|ρ| > 0.7 and P < 0.05) with physicochem. properties and VFCs, by redundancy anal. (RDA) and two-way orthogonal partial least squares (O2PLS) anal. Ultimately, based on the results, a metabolic map of dominant genera in BGRW was established. Our findings provided detailed information on the dynamic changes of physicochem. properties and VFCs and selection of beneficial strains to improve the quality of BGRW. The experimental process involved the reaction of Diethyl succinate(cas: 123-25-1).Safety of Diethyl succinate

The Article related to microbiota physicochem volatile flavor component glutinous rice wine fermentation, black glutinous rice wine, correlation analysis, high throughput sequencing, microbial communities, physicochemical properties, volatile components and other aspects.Safety of Diethyl succinate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Okumura, Mikiko; Nakamata Huynh, Stephanie M.; Pospech, Jola; Sarlah, David published an article in 2016, the title of the article was Arenophile-Mediated Dearomative Reduction.Formula: C10H14O3 And the article contains the following content:

A dearomative reduction of simple arenes has been developed which employs a visible-light-mediated cycloaddition of arenes with an N-N-arenophile (N-methyl-1,2,4-triazoline-3,5-dione, MTAD) and in situ diimide reduction Subsequent cycloreversion or fragmentation of the arenophile moiety affords 1,3-cyclohexadienes, e.g., I, or 1,4-diaminocyclohex-2-enes, e.g., II, compounds that are not synthetically accessible using existing dearomatization reactions. Importantly, this strategy also provides numerous opportunities for further derivatization as well as site-selective functionalization of polynuclear arenes. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Formula: C10H14O3

The Article related to arene methyltriazolinedione dearomative cycloaddition diimide reduction light cycloreversion fragmentation, cyclohexadiene preparation, cycloreverdiaminocyclohexene preparation, arenes, arenophiles, dearomatization, functionalization, photochemistry and other aspects.Formula: C10H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 15, 2016, Xie, Sheng-Ming; Zhang, Jun-Hui; Fu, Nan; Wang, Bang-Jin; Chen, Ling; Yuan, Li-Ming published an article.Safety of (R)-Methyl 3-hydroxybutanoate The title of the article was A chiral porous organic cage for molecular recognition using gas chromatography. And the article contained the following:

Mol. organic cages as shape-persistent organic mols. with permanent and accessible cavities have attracted a lot of interest because of their importance as host-guest systems. Herein, the authors report a chiral porous organic cage (POC) CC9 diluted with a polysiloxane OV-1701 to fabricate a CC9-coated capillary column, which was used for the high-resolution gas chromatog. separation of organic compounds, including positional isomers and racemates. On the porous organic cage CC9-coated capillary column, a large number of racemic compounds such as chiral alcs., esters, ethers and epoxides can be resolved without derivatization. By comparing the chiral recognition ability of the CC9-coated column with the com. available β-DEX 120 column and the POC CC3-R coated column recently reported by the authors’ group, the CC9-coated column offered good resolution during the separation of some racemates, that were not separated using the β-DEX 120 column or POC CC3-R coated column. Therefore, the CC9-coated column can be complementary to the β-DEX 120 column and CC3-R coated column. The CC9-coated column exhibited great potential for application in the separation of positional isomers and enantiomers with great selectivity, high resolution and good reproducibility. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Safety of (R)-Methyl 3-hydroxybutanoate

The Article related to porous organic cage stationary phase gc positional isomer separation, chiral porous organic cage stationary phase gas chromatog enantioseparation, capillary column, chiral separation, chiral stationary phase, gas chromatography, porous organic cage and other aspects.Safety of (R)-Methyl 3-hydroxybutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 2, 2021, Liao, Zhehui; Zhang, Jiantao; Cao, Tongxiang; Zhu, Shifa published an article.Quality Control of Methyl 2-cyclopentanonecarboxylate The title of the article was Copper-Catalyzed Asymmetric Synthesis of Bicyclo[3.n.1]alkenones. And the article contained the following:

A series of highly strained bicyclo[3.n.1]alkenones such as I (R = Me, Et, i-Pr) have been successfully constructed in good to excellent enantioselectivities and moderate to good yields by copper-catalyzed formal [3+3] cycloaddition reaction of 2-oxocycloalkanecarboxylates and aryl vinyl ketones or arylethenyl vinyl ketones via nonracemic oxoalkyl-substituted oxocycloalkanecarboxylates such as II (R = Me, Et, i-Pr). The cycloadducts were selectively converted into various valuable bicyclic ring systems holding considerable potential for the construction of natural and bioactive compounds containing a [3.n.1] moiety. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Quality Control of Methyl 2-cyclopentanonecarboxylate

The Article related to bicycloalkenone enantioselective preparation, copper catalyst enantioselective cycloaddition ketocycloalkanecarboxylate aryl vinyl ketone, enantioselective copper catalyzed michael addition oxocycloalkanecarboxylate vinyl ketone cyclocondensation and other aspects.Quality Control of Methyl 2-cyclopentanonecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Marquardt, Fabian; Stoecker, Cornelia; Gartzen, Rita; Heine, Elisabeth; Keul, Helmut; Moeller, Martin published an article in 2018, the title of the article was Novel antibacterial polyglycidols: relationship between structure and properties.Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride And the article contains the following content:

Antimicrobial polymers are an attractive alternative to low mol. weight biocides, because they are non-volatile, chem. stable, and can be used as non-releasing additives. Polymers with pendant quaternary ammonium groups and hydrophobic chains exhibit antimicrobial properties due to the electrostatic interaction between polymer and cell wall, and the membrane disruptive capabilities of the hydrophobic moiety. Herein, the synthesis of cationic-hydrophobic polyglycidols with varying structures by post-polymerization modification is presented. The antimicrobial properties of the prepared polyglycidols against E. coli and S. aureus are examined Polyglycidol with statistically distributed cationic and hydrophobic groups (cationic-hydrophobic balance of 1:1) is compared to (i) polyglycidol with a hydrophilic modification at the cationic functionality; (ii) polyglycidol with both-cationic and hydrophobic groups-at every repeating unit; and (iii) polyglycidol with a cationic-hydrophobic balance of 1:2. A relationship between structure and properties is presented. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to escherichia staphylococcus erythrocyte polyglycidol antibacterial structure property relationship, antimicrobial polymers, functional polyethers, multifunctional polyglycidol, post-polymerization functionalization, structure-property relationship and other aspects.Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Holloway, Joshua O.; Mertens, Chiel; Du Prez, Filip E.; Badi, Nezha published an article in 2019, the title of the article was Automated synthesis protocol of sequence-defined oligo-urethane-amides using thiolactone chemistry.Electric Literature of 6038-19-3 And the article contains the following content:

An automated, iterative protocol for the synthesis of multifunctional, sequence-defined oligo-urethane-amides using thiolactone chem. is reported. Here, sequenced functionalization of the backbone is easily introduced using com. available primary amines. The chem. is carried out on solid phase using different supports for better optimization of the synthetic protocol and in order to demonstrate the versatility of the approach. This technique is very effective for iterative synthesis and solid-phase chem. and enables the exploration of full automation of this approach using a robotic peptide synthesizer. As a result, this automated protocol allows for the synthesis of a sequence-defined nonamer of high purity. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Electric Literature of 6038-19-3

The Article related to sequence defined oligo urethane amide synthesis peptide, amine solid phase peptide synthesis robotic synthesizer thiolactone aminolysis, aminolysis reaction kinetics, automated synthesis, sequence-controlled polymers, solid-phase, thiolactone and other aspects.Electric Literature of 6038-19-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chaudhury, Aritra; Maity, Sajal K.; Ghosh, Rina published an article in 2014, the title of the article was Efficient routes toward the synthesis of the d-rhamno-trisaccharide related to the A-band polysaccharide of Pseudomonas aeruginosa.COA of Formula: C10H14O3 And the article contains the following content:

The present work describes efficient avenues for the synthesis of the trisaccharide repeating unit [α-D-Rhap-(1→3)-α-D-Rhap-(1→3)-α-D-Rhap] associated with the A-band polysaccharide of Pseudomonas aeruginosa. One of the key steps involved 6-O-deoxygenation of either partially or fully acylated 4,6-O-benzylidene-1-thiomannopyranoside by radical-mediated redox rearrangement in high yields and regioselectivity. The D-rhamno-thioglycosides so obtained allowed efficient access to the trisaccharide target via stepwise glycosylation as well as a one-pot glycosylation protocol. In a different approach, a 4,6-O-benzylidene D-manno-trisaccharide derivative was synthesized, which upon global 6-O-deoxygenation followed by deprotection generated the target d-rhamno-trisaccharide. The application of the reported regioselective radical-mediated deoxygenation on 4,6-O-benzylidene d-manno thioglycoside (hitherto unexplored) has potential for ramification in the field of synthesis of oligosaccharides based on 6-deoxy hexoses. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).COA of Formula: C10H14O3

The Article related to rhamno trisaccharide sequential glycosylation synthesis pseudomonas aeruginosa, a-band polysaccharide, d-rhamno-trisaccharide, pseudomonas aeruginosa, deoxygenation on thioglycoside, multivalent glycosystems, one-pot sequential glycosylation and other aspects.COA of Formula: C10H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics