Tag: 100-200

On July 31, 2013, Ahn, Sung-Hyun; Choi, Moo-Seok; Im, Jun-Seop; Sheikh, Rizwan; Park, Yeung-Ho published an article.Recommanded Product: 3976-69-0 The title of the article was Improved method for immobilization of a chiral complex on PTA/alumina for asymmetric hydrogenation of a β-ketoester. And the article contained the following:

Ru-BINAP was immobilized on alumina using the well-known Augustine method with heteropoly acid (HPA) as the anchoring agent (“Augustine catalyst”). The supported catalyst was tested in a high-pressure reaction such as asym. hydrogenation of Me acetoacetate (MAA). Since the activity of the supported catalyst was significantly lower than that of the homogeneous catalyst, the solvent used in preparing PTA/Al2O3 was changed from ethanol to a solution of HCl. The modified supported catalyst (“modified Augustine catalyst”) exhibited higher conversion, better selectivity, and improved enantioselectivity compared with the catalyst prepared by the Augustine method. The modified Augustine catalyst also produced β-hydroxyesters with good yield and enantioselectivity in asym. hydrogenation of various β-ketoester derivatives The modified Augustine catalyst was examined by FT-IR, XRD, NH3-TPD, and ICP-AES, which revealed the existence of strong acid sites formed by HPA with a Keggin structure. These results were attributed to the effect of enhanced acidity on the modified Augustine catalyst. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Recommanded Product: 3976-69-0

The Article related to phosphotungstic acid ruthenium binap alumina asym hydrogenation beta ketoester, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Recommanded Product: 3976-69-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On November 28, 2012, Osawa, Tsutomu; Lee, I-Yin Sandy; Ikeda, Shinji; Kitamura, Takayuki; Inoue, Yoshihisa; Borovkov, Victor published an article.Product Details of 3976-69-0 The title of the article was Simplified preparation of chirally modified nickel catalyst for enantioselective hydrogenation: A step forward to industrial use. And the article contained the following:

A chirally modified nickel catalyst for the enantio-differentiating hydrogenation of β-ketoesters is conventionally prepared by immersing the pre-activated metallic nickel into an aqueous solution of enantiopure tartaric acid (so called “modification step”). During the pre-activation step, nickel precursor is commonly treated with hydrogen gas at elevated temperatures of up to 473 K. The X-ray photoelectron spectral examinations of chirally modified nickel catalysts obtained under the different modification conditions revealed that the chiral modification process itself plays a major role in activating the nickel surface while the pre-activation procedure is a less important factor. The corresponding enantio-differentiating hydrogenations of Me acetoacetate in the liquid phase using the prepared chiral catalysts unambiguously confirmed this conclusion, providing quant. conversions and high enantioselectivities of up to 90%. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Product Details of 3976-69-0

The Article related to chirally nickel catalyst enantioselective hydrogenation a forward industrial, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Product Details of 3976-69-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On May 6, 2022, Tang, Ling; Jiang, Shuangshuang; Huang, Xinmiao; Song, Zhiyong; Wang, Jian-bo; Ma, Ming; Chen, Bo; Ma, Yuanhong published an article.Safety of Ethyl indolizine-1-carboxylate The title of the article was Cascade of C(sp2)-H Addition to Carbonyl and C(sp2)-CN/C(sp2)-H Coupling Enabled by Bronsted Acid: Construction of Benzo[a]carbazole Frameworks. And the article contained the following:

Herein, an unprecedented cascade reaction of C(sp2)-H addition to carbonyl and the C(sp2)-CN/C(sp2)-H coupling of 2-(2-oxo-2-arylethyl)benzonitriles with indoles enabled by com. available TsOH·H2O was reported. The protocol represented the first metal-free C(sp2)-CN/C(sp2)-H coupling, affording a new route for the synthesis of various benzo[a]carbazole derivatives I [R1 = H, 3-OMe, 3-F, etc.; R2 = Ph, 2-MeC6H4, 4-ClC6H4, etc.; R3 = H, Me, Ph; R4 = H, Me, Et; R5 = H, 9-F, 8-Br, etc.] with a broad substrate scope, high yields, and simple conditions. The experimental process involved the reaction of Ethyl indolizine-1-carboxylate(cas: 93476-46-1).Safety of Ethyl indolizine-1-carboxylate

The Article related to benzocarbazole preparation, indole benzonitrile cascade addition coupling, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Safety of Ethyl indolizine-1-carboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On October 31, 2016, Osawa, Tsutomu; Kawajiri, Satoru; Ishisaki, Anna published an article.Application of 3976-69-0 The title of the article was Enantio-differentiating hydrogenation of methyl acetoacetate over tartaric acid modified Ni catalyst at atmospheric pressure of hydrogen assisted by hydrogen transfer reaction. And the article contained the following:

The enantio-differentiating hydrogenation of Me acetoacetate was carried out under the atm. pressure of hydrogen (gage pressure: 0 MPa) assisted by hydrogen transfer from 2-propanol. It was revealed that the tartaric acid-NaBr-modified supported nickel catalyst, especially Ni/CeO2, produced a higher enantioselectivity than the modified Raney nickel catalyst under the atm. pressure of hydrogen. Catalyst preparation and hydrogenation conditions for the hydrogenation over the modified Ni/CeO2 were studied. The Ni/CeO2 prepared by calcination at 773 K and reduction at 773 K gave the best result. The enantioselectivity of 64% (22% conversion) was attained under the atm. pressure of hydrogen at 323 K assisted the by hydrogen transfer from the solvent. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Application of 3976-69-0

The Article related to methyl acetoacetate tartaric acid modified hydrogen transfer reaction, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Application of 3976-69-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On March 18, 2011, Yang, Yuzhu; Chen, Li; Zhang, Zhaoguo; Zhang, Yuhong published an article.Formula: C11H11NO2 The title of the article was Palladium-Catalyzed Oxidative C-H Bond and C=C Double Bond Cleavage: C-3 Acylation of Indolizines with α,β-Unsaturated Carboxylic Acids. And the article contained the following:

A novel palladium-catalyzed C-3 acylation of indolizines with α,β-unsaturated carboxylic acids via C-H bond and C=C double bond cleavage under oxidative conditions is described. E.g., in presence of PdCl2 and K2CrO4, acylation of indolizine I with cinnamic acid II gave 64% III. The regioselectivity is assisted by the carboxylic group, and the selection of the oxidant is crucial to the reaction. The experimental process involved the reaction of Ethyl indolizine-1-carboxylate(cas: 93476-46-1).Formula: C11H11NO2

The Article related to palladium catalyst acylation indolizine unsaturated carboxylic acid, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Formula: C11H11NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shen, Chuang; Yang, Yuzhu; Liu, Zhanxiang; Zhang, Yuhong published an article in 2014, the title of the article was Palladium-Catalyzed Direct C-3 Alkynylation of Indolizines with (2,2-Dibromovinyl)arenes.Electric Literature of 93476-46-1 And the article contains the following content:

The direct C-3 alkynylation of indolizines with (2,2-dibromovinyl)arenes in the presence of palladium catalyst has been developed. This novel protocol showed wide substrate scope with respect to both indolizines and dibromoalkenes. Also this method was characterized with high efficiency and good functional group tolerance. The experimental process involved the reaction of Ethyl indolizine-1-carboxylate(cas: 93476-46-1).Electric Literature of 93476-46-1

The Article related to alkynylation indolizine dibromovinylarene palladium catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Electric Literature of 93476-46-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 30, 2014, Lu, Guo-ping; Lin, Ya-mei published an article.Quality Control of (Trimethoxymethyl)benzene The title of the article was A base-induced ring-opening process of 2-substituted-1,3,4-oxadiazoles for the generation of nitriles at room temperature. And the article contained the following:

A novel base-catalyzed 1,3,4-oxadiazole fragmentation for the synthesis of nitriles at room temperature was reported. This reaction was performed under transition-metal-free conditions, and provided a new ring cleavage reaction of 1,3,4-oxadiazoles in organic synthesis. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Quality Control of (Trimethoxymethyl)benzene

The Article related to oxadiazole aryl ring opening reaction, aryl nitrile preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Nitriles, Isonitriles, and Acyl Cyanides and other aspects.Quality Control of (Trimethoxymethyl)benzene

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kotani, Shunsuke; Sakamoto, Midori; Osakama, Kazuki; Nakajima, Makoto published an article in 2015, the title of the article was A Sterically Congested α-Cyanoamine as a Cyanating Reagent: Cyanation of Acetals and Orthoesters.Product Details of 707-07-3 And the article contains the following content:

The cyanation of acetals and ortho-esters by using a sterically congested α-cyanoamine as a cyanation reagent was investigated. The α-cyanoamine effectively facilitated cyanation in the presence of trichlorosilyl triflate to produce a variety of cyanated adducts in excellent yields. Anal. of the reaction mixture by 1H NMR spectroscopy revealed that trichlorosilyl triflate produced an oxocarbenium cation species as an intermediate. Under optimized conditions the synthesis of the target compounds was achieved using 1,1,1-trifluoromethanesulfonic acid trichlorosilyl ester as a reagent and 2-(dicyclohexylamino)acetonitrile (cyanation agent amine-cyanide) and (dimethoxymethyl)benzene (benzaldehyde acetal), (3,3-dimethoxy-1-propen-1-yl)benzene, (dimethoxymethyl)cyclohexane, 1,1′-[(phenylmethylene)bis(oxymethylene)]bis[benzene], 2-phenyl-1,3-dioxolane (cyclic acetal) as starting materials. The title compounds thus formed included α-(methoxy)benzeneacetonitrile derivatives, α-(methoxy)-1-naphthaleneacetonitrile, 2-methoxy-4-phenyl-2-butenenitrile, α-(2-hydroxyethoxy)benzeneacetonitrile. Ortho-ester reactants included (trimethoxymethyl)benzene, 1,1′,1”-[methylidynetris(oxy)]tris[ethane] and 1,1,1-triethoxypentane. Products therefrom included α,α-dimethoxybenzeneacetonitrile. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Product Details of 707-07-3

The Article related to alkoxy alkanenitrile nitrile cyanation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Nitriles, Isonitriles, and Acyl Cyanides and other aspects.Product Details of 707-07-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 2, 2014, Suresh, Dhanusu; Kanagaraj, Kuppusamy; Pitchumani, Kasi published an article.Safety of (Trimethoxymethyl)benzene The title of the article was Microwave promoted one-pot synthesis of 2-aryl substituted 1,3,4-oxadiazoles and 1,2,4-oxadiazole derivatives using Al3+-K10 clay as a heterogeneous catalyst. And the article contained the following:

An efficient, inexpensive method is developed for the one-pot synthesis of 2-aryl substituted 1,3,4-oxadiazoles and 1,2,4-oxadiazoles starting from acid hydrazides and tri-Me orthoformate under solvent-free, microwave conditions using a reusable Al3+-K10 montmorillonite clay as a heterogeneous catalyst. The novelty of the present study lies in the synthesis of oxadiazole and benzimidazole moieties in a one-pot process in high yield from easily available precursors and catalysts under mild conditions. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Safety of (Trimethoxymethyl)benzene

The Article related to aryl oxadiazole derivative microwave preparation aluminum montmorillonite clay catalyst, crystal structure ethylethyloxadiazoleylbenzoimidazole, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Safety of (Trimethoxymethyl)benzene

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On August 10, 2022, Yang, Guoqiang; Wu, Hua; Gallarati, Simone; Corminboeuf, Clemence; Wang, Qian; Zhu, Jieping published an article.COA of Formula: C9H8F2O2 The title of the article was Migrative Carbofluorination of Saturated Amides Enabled by Pd-Based Dyotropic Rearrangement. And the article contained the following:

Herein, a palladium-catalyzed migrative carbofluorination of saturated amides enabled by the activation of both the C(sp3)-H and the Cquaternary-Cσ bonds was reported for the synthesis of functionalized amides. In this transformation, the α-quaternary carbon of Weinreb amides was converted to α-tertiary fluoride with concurrent migration of an aryl or an amido group from the α- to β-carbon. DFT calculations indicate that the dyotropic rearrangement proceeds through an unusual anti-selective [2.1.0] bicyclic transition state. The experimental process involved the reaction of Methyl 2-(2,6-difluorophenyl)acetate(cas: 872046-08-7).COA of Formula: C9H8F2O2

The Article related to functionalized amide preparation, saturated amide dyotropic rearrangement migrative carbofluorination palladium catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.COA of Formula: C9H8F2O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics