Tag: 100-200

On February 1, 2020, Watanabe, Michiko; Sasaki, Takamitsu; Takeshita, Jun-ichi; Kushida, Madoka; Shimizu, Yuki; Oki, Hitomi; Kitsunai, Yoko; Nakayama, Haruka; Saruhashi, Hitomi; Ogura, Rui; Shizu, Ryota; Hosaka, Takuomi; Yoshinari, Kouichi published an article.Application of 517-23-7 The title of the article was Application of cytochrome P450 reactivity on the characterization of chemical compounds and its association with repeated-dose toxicity. And the article contained the following:

Repeated-dose toxicity (RDT) studies are one of the critical studies to assess chem. safety. There have been some studies attempting to predict RDT endpoints based on chem. substructures, but it remains very difficult to establish such a method, and a more detailed characterization of chem. compounds seems necessary. Cytochrome P450s (P450s) comprise multiple forms with different substrate specificities and play important roles in both the detoxification and metabolic activation of xenobiotics. In this study, we investigated possible use of P 450 reactivity of chem. compounds to classify the compounds A total of 148 compounds with available rat RDT test data were used as test compounds and subjected to inhibition assays against 18 human and rat P450s. Among the tested compounds, 82 compounds inhibited at least one P 450 form. Hierarchical clustering analyses using the P 450 inhibitory profiles divided the 82 compounds into nine groups, some of which showed characteristic chem. and biol. properties. Principal component analyses of the P 450 inhibition data in combination with the calculated chem. descriptors demonstrated that P 450 inhibition data were plotted differently than most chem. descriptors in the loading plots. Finally, association analyses between P 450 inhibition and RDT endpoints showed that some endpoints related to the liver, kidney and hematol. were significantly associated with the inhibition of some P450s. Our present results suggest that the P 450 reactivity profiles can be used as novel descriptors for characterizing chem. compounds for the investigation of the toxicity mechanism and/or the establishment of a toxicity prediction model. The experimental process involved the reaction of 3-Acetyldihydrofuran-2(3H)-one(cas: 517-23-7).Application of 517-23-7

The Article related to cytochrome chem compound repeated dose toxicity, chemical descriptors, cytochrome p450, enzyme inhibition, repeated-dose toxicity, toxicity prediction, Pharmacology: Drug Interactions and General Pharmacology and other aspects.Application of 517-23-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fraser, Robert R.; Raby, Bruce F. published an article in 1972, the title of the article was Substituent effect on geminal coupling constants in allylic methylene groups.Product Details of 37480-41-4 And the article contains the following content:

The geminal proton-proton coupling constants were determined for the allylic methylene protons in a series of selectively deuterated cyclohexene derivatives The effect of substituents β to the methylene group on 2J agrees with theoretical calculations Electron-withdrawing substituents cause a neg. shift and electron-donating substituents cause a pos. shift in 2J, the total variation being 2.9 Hz. This effect is larger than that exerted by para substituents in benzylic systems as would be expected for a more polarizable double bond. The 2J’s correlate poorly with the existing substituent parameters but correlate well with the shift of the olefinic protons adjacent to the double bond. This correlation is interpreted as evidence that the change in 2J is produced primarily by a resonance interaction of the substituent with the double bond resulting in a change in the hyperconjugative withdrawal of electrons from the adjacent methylene group. The experimental process involved the reaction of Methyl 1-methyl-4-oxocyclohexanecarboxylate(cas: 37480-41-4).Product Details of 37480-41-4

The Article related to substituent effect nmr allylic methylene, Physical Organic Chemistry: Spectral and Related Studies and other aspects.Product Details of 37480-41-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xie, Haopu; Sheng, Dekun; Zhou, Yan; Xu, Shaobin; Wu, Haohao; Tian, Xinxin; Sun, Yinglu; Liu, Xiangdong; Yang, Yuming published an article in 2020, the title of the article was Thermally healable polyurethane with tailored mechanical performance using dynamic crosslinking motifs.Related Products of 517-23-7 And the article contains the following content:

Materials with self-healing abilities have gained tremendous attention in recent years but combing excellent mech. performance and splendid self-healing capacity into a single polymer material is still a great challenge. In this study, a self-healing polyurethane (SHP) material was prepared by constructing a dynamic crosslinked network via quadruple hydrogen bonds formed from 5-(2-hydroxyethyl)-6-methyl-2-aminouracil (UPy). The mech. properties of the materials could be conveniently tuned by adjusting the dynamic crosslinked d. The optimal sample, SHP-75, has excellent mech. performance, showing high tensile strength (27.02 MPa), excellent stretchability (1300%), and prominent toughness (111.37 MJ m-3). Despite such great mech. properties, SHP-75 exhibited superior self-healing abilities and could fully obtain its initial mech. strength after repairing at 80°C for 24 h. A self-healing conductive electrode was further constructed to demonstrate its application prospects in the field of sensing. The experimental process involved the reaction of 3-Acetyldihydrofuran-2(3H)-one(cas: 517-23-7).Related Products of 517-23-7

The Article related to thermally healable polyurethane tailored dynamic crosslinking motif, Plastics Manufacture and Processing: Preparation Of Resins and other aspects.Related Products of 517-23-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ji, Xiaoyue published an article in 2020, the title of the article was Investigation of the volatile components in commercial sufu (Chinese fermented soybean curd) based on HS-SPME/GC-MS combined with multivariate statistical analysis.COA of Formula: C8H14O4 And the article contains the following content:

Volatile flavor substances in com. sufu samples of different brands were investigated by headspace solid-phase microextraction (HS-SPME) coupled with gas chromatog.-mass spectrometry (GC-MS). Principal component anal. and cluster anal. of volatile substances for evaluating and distinguishing between nine com. sufu samples were carried out. The results were that a total of 36-six volatiles were identified successfully in nine different brands of sufu, including 7 alcs., 22 esters, and 6 other organic compounds Sufu can be classified into five categories by cluster anal. according to the types and contents of volatiles, and it was determined that the predominant source of difference among volatiles was the difference of esters. Meanwhile, the principal component score plot described the differences and classifications of sufu samples. It was noted that types and contents of volatiles can reflect the sufu taste and analyzing the volatile organic components in sufu provides us with valuable information. HS-SPME-GC/MS combined with multivariate statistical anal. was developed to comprehensively compare volatile components in nine brands of com. sufu with large market share in China. The anal. results indicated that there were obvious differences in the types and contents of volatile components. In this study, the difference in volatile components between the nine brands of sufu was studied and the source of some certain chem. substances were traced to explain for the special sufu flavor. This feasible method may be used as a reference for further research on the flavor of sufu and may help formulators, who are trying to improve the taste and quality of food products. The experimental process involved the reaction of Diethyl succinate(cas: 123-25-1).COA of Formula: C8H14O4

The Article related to chinese fermented soybean curd volatile component hsspme gcms, Food and Feed Chemistry: Dairy Products (Including Butter) and other aspects.COA of Formula: C8H14O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 18, 2018, Zhao, Shilin; Liu, Meng; Zhao, Liang; Zhu, Lingli published an article.COA of Formula: C6H8O3 The title of the article was Influence of Interactions among Three Biomass Components on the Pyrolysis Behavior. And the article contained the following:

Pyrolysis experiments between 25 and 800° for three main components (cellulose, hemicellulose, and lignin) mixed in different proportions were conducted on a thermogravimetric analyzer (TGA) and pyrolysis-gas chromatog./mass spectrometer (Py-GC/MS). The interactions between the three main components during the pyrolysis of biomass were explored from two aspects, namely thermogravimetric properties and pyrolysis products. The results indicate that interactions existed among the three biomass components in the co-pyrolysis process. The presence of lignin significantly reduces the pyrolysis rate of cellulose and inhibits the formation of sugars (mainly levoglucosan) in the pyrolysis of cellulose and hemicellulose. However, the existence of cellulose or hemicellulose greatly promotes the pyrolysis of lignin to produce phenolic compounds This finding is meaningful for the application of biomass pyrolysis. The experimental process involved the reaction of 3-Acetyldihydrofuran-2(3H)-one(cas: 517-23-7).COA of Formula: C6H8O3

The Article related to cellulose hemicellulose lignin biomass pyrolysis, Cellulose, Lignin, Paper, and Other Wood Products: General and other aspects.COA of Formula: C6H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Maximuck, William J.; Ganzmann, Carola; Alvi, Scheherzad; Hooda, Karan R.; Gladysz, John A. published an article in 2020, the title of the article was Rendering classical hydrophilic enantiopure Werner salts [M(en)3]n+nX- lipophilic (M/n = Cr/3, Co/3, Rh/3, Ir/3, Pt/4); new chiral hydrogen bond donor catalysts and enantioselectivities as a function of metal and charge.Application of 10472-24-9 And the article contains the following content:

Known hydrophilic halide salts of the title compounds are converted to new lipophilic BArf- (B(3,5-C6H3(CF3)2)4-) salts. These are isolated as hydrates (Λ- or Δ-[M(en)3]n+nBArf-·zH2O; z = 17-9) and characterized by NMR (acetone-d6) and microanalyses. Thermal stabilities are probed by capillary thermolyses and TGA and DSC measurements (onset of dehydration 71-151°C). In the presence of tertiary amines, they are effective catalysts for enantioselective Michael type carbon-carbon or carbon-nitrogen bond forming additions of 1,3-dicarbonyl compounds (acceptors: trans-β-nitrostyrene, di-tert-butylazodicarboxylate, 2-cyclopenten-1-one; average ee = 33%, 52%, 17%). Effects of the metal and charge upon enantioselectivities are analyzed. A number of properties appear to correlate to the NH Bronsted acidity order ([Pt(en)3]4+ > [Cr(en)3]3+ > [Co(en)3]3+ > [Rh(en)3]3+ > [Ir(en)3]3+). The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Application of 10472-24-9

The Article related to transition metal ethylene complex preparation michael reaction catalyst, thermal stability transition metal ethylene complex, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Application of 10472-24-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 30, 2013, Keul, Helmut; Mommer, Stefan; Moeller, Martin published an article.Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride The title of the article was Poly(amide urethane)s with functional/reactive side groups based on a bis-cyclic bio-based monomer/coupling agent. And the article contained the following:

Glycerol and D,L-homocysteine thiolactone – two bio-based building blocks – were used to prepare a bis-cyclic AA’ monomer (or coupler) with an ethylene carbonate and a thiolactone ring linked by an O-Me urethane spacer. On reaction of this monomer with diamines at 70 °C poly(amide urethane)s with pendant thioethyl and hydroxymethyl side groups are produced in one step. Monodisperse diamines of low mol. weight (MW), monodisperse amino telechelic poly(ethylene oxide) (MW = 897.10) and polydisperse amino telechelic polytetrahydrofuran (Mn = 1100) were used as amine building blocks. By reaction of the coupler with diamines at room temperature only the thiolactone ring is converted. Consequently, a bis(ethylene carbonate) bis(thiol) is obtained if one equivalent diamine is reacted with two equivalent of coupler. Reaction of this intermediate with a second diamine leads to poly(amide urethane)s with pendant thioethyl and hydroxymethyl side groups and alternating amine building blocks. Post-polymerization modification of thiol side groups leads to polymers with designed properties. The microstructure of the obtained polymers was proven by 1H NMR and Raman spectroscopy; the mol. weights were determined by size exclusion chromatog. The experimental process involved the reaction of 3-Aminodihydrothiophen-2(3H)-one hydrochloride(cas: 6038-19-3).Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

The Article related to polyamide polyurethane polyoxyalkylene polyester glass transition temperature, Plastics Manufacture and Processing: Preparation Of Resins and other aspects.Quality Control of 3-Aminodihydrothiophen-2(3H)-one hydrochloride

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On November 5, 2018, Wang, Jia; Xu, Chao; Zhong, Zhaoping; Deng, Aidong; Hao, Naijia; Li, Mi; Meng, Xianzhi; Ragauskas, Arthur J. published an article.Computed Properties of 517-23-7 The title of the article was Catalytic Conversion of Bamboo Sawdust over ZrO2-CeO2/γ-Al2O3 to Produce Ketonic Hydrocarbon Precursors and Furans. And the article contained the following:

A series of metal oxides including ZrO2/γ-Al2O3, CeO2/γ-Al2O3, and ZrO2-CeO2/γ-Al2O3 were synthesized and employed to conduct catalytic fast pyrolysis of bamboo sawdust via an anal. pyrolyzer/gas chromatograph/mass spectrometer (Py-GC/MS) to produce hydrocarbon precursors such as ketones and furans. Exptl. results illustrated that the use of metal oxides enhanced the formation of ketones and monoarom. hydrocarbons compared to catalyst-free trial. Among the metal oxides, ZrO2-CeO2/γ-Al2O3 exhibited the most significant ketonization and aldol condensation activities yielding the highest concentration of linear and cyclic ketones. In addition, nonacidic oxygenates such as furfural, acetol, butanedial, 2,3-dihydrobenzofuran, and Me acetate, were efficiently converted into hydrocarbon precursors over metal oxides. A dual catalytic bed system integrating ZrO2-CeO2/γ-Al2O3 and HZSM-5 significantly facilitated the production of aromatic hydrocarbons compared to pure HZSM-5 catalytic run. The use of ZrO2-CeO2/γ-Al2O3 mixed with HZSM-5 mode maximized the formation of xylenes, while ZrO2-CeO2/γ-Al2O3 mixed with bamboo sawdust catalytic trial increased the concentration of benzene, toluene, and alkylbenzenes. The experimental process involved the reaction of 3-Acetyldihydrofuran-2(3H)-one(cas: 517-23-7).Computed Properties of 517-23-7

The Article related to bamboo sawdust conversion zirconia ceria alumina ketonic hydrocarbon furan, Cellulose, Lignin, Paper, and Other Wood Products: General and other aspects.Computed Properties of 517-23-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 18, 2018, Li, Mei; Zhang, Rongchun; Li, Xiaohui; Wu, Qiang; Chen, Tiehong; Sun, Pingchuan published an article.Recommanded Product: 517-23-7 The title of the article was High-performance recyclable cross-linked polyurethane with orthogonal dynamic bonds: The molecular design, microstructures, and macroscopic properties. And the article contained the following:

Polyurethane materials (PUs) have been widely used in industry and daily life due to the versatile chem. However, despite the rapid advance in synthetic chem., it still remains a significant challenge for the facile fabrication of PUs with a single crosslinked network embedded with excellent mech. properties and recyclability. Herein, in this study, we proposed a simple strategy to fabricate a high-performance recyclable crosslinked PU and revealed the relationship between microscopic structure and macroscopic properties. The UPy (2-ureido-4-[1H]-pyrimidione) motifs were incorporated into the backbone chains of PUs, where the quadruple hydrogen bonding interactions between UPy dimers can significantly enhance the mech. strength and toughness. Furthermore, a single small mol. Diels-Alder adduct was utilized as the chem. crosslinker, rendering the final crosslinked PUs healable and recyclable. The thermal reversibility of the Diels-Alder reaction was well verified by DSC and solid-state NMR spectroscopy. Notably, it was found that the incorporation of UPy motifs could enhance the strain-induced crystallization (SIC), leading to a large stress at break. The structural and dynamic changes induced by SIC were quant. addressed by proton multiple-quantum NMR spectroscopy and SAXS experiments, where SIC further imposed restrictions on the mobility of surrounding polymer chains in the soft domain and led to the change of microphase separated nanostructures. Overall, a simple strategy is proposed here for the facile fabrication of high performance recyclable PUs, and the detailed investigation here on the structure-property relationship may further provide insights into developing high performance polymeric materials. The experimental process involved the reaction of 3-Acetyldihydrofuran-2(3H)-one(cas: 517-23-7).Recommanded Product: 517-23-7

The Article related to recyclable polyurethane orthogonal dynamic bond design microstructure, Plastics Manufacture and Processing: Preparation Of Resins and other aspects.Recommanded Product: 517-23-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xu, Kangming; Chen, Guoqing; Zhao, Mingjie; He, Weiyi; Hu, Qiaoman; Pu, Yong published an article in 2022, the title of the article was Transparent, self-recoverable, highly tough, puncture and tear resistant polyurethane supramolecular elastomer with fast self-healing capacity via “hard-soft” hard domain design.Application of 517-23-7 And the article contains the following content:

The integration of superior mech. properties and fast healing efficiency for self-healing polyurethane supramol. elastomers is challenging due to the confliction between high chain mobility for healing and high chain rigidity for mech. properties. Herein, a strategy to design a “hard-soft” hard domain by the cooperation of quadruple hydrogen bonds (HBs) in the mainchain as restriction units and single HBs in the side chain as diffusion units is reported. The resulting transparent supramol. elastomer exhibited fast self-recoverability, good puncture resistance and superior mech. properties with a tensile strength of 20.5 MPa, an extensibility of 2043.7%, a toughness of 146.1 MJ m-3 and a tear resistance of 13.8 kJ m-2. Moreover, the fast self-healing capacity (healing efficiency > 82% within 3 h under moderate condition) was realized due to the soft effects of weak HBs in the side chain on the strong HBs in the mainchain. Taking advantage of the merits of the supramol. elastomer, a flexible sensor was simply fabricated, which showed good self-repairable and stable sensing properties. Thus, the elastomer has great potential in the field of flexible electronics and wearable devices. The experimental process involved the reaction of 3-Acetyldihydrofuran-2(3H)-one(cas: 517-23-7).Application of 517-23-7

The Article related to polyurethane supramol elastomer self healing transparent puncture tear resistance, Synthetic Elastomers and Natural Rubber: Elastomer Synthesis and other aspects.Application of 517-23-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics