Tag: 100-200

Key Odorants of Raw and Cooked Green Kohlrabi (Brassica oleracea var. gongylodes L.) was written by Marcinkowska, Monika;Frank, Stephanie;Steinhaus, Martin;Jelen, Henryk H.. And the article was included in Journal of Agricultural and Food Chemistry in 2021.Product Details of 695-06-7 This article mentions the following:

Volatile compounds of raw and cooked green kohlrabi were investigated using a sensomics approach. A total of 55 odor-active compounds were detected and identified in raw and cooked green kohlrabi using GC-O. Twenty-eight odor-active compounds with high flavor dilution (FD) factors ranging from 64 to 1024 were quantitated, and odor activity values (OAVs) were determined Eight compounds showed high OAVs in raw and cooked kohlrabi: five sulfur compounds (di-Me trisulfide, Me 2-methyl-3-furyl disulfide, and three isothiocyanates (1-isothiocyanato-3-(methylsulfanyl)propane, benzyl isothiocyanate, and 1-isothiocyanato-4-(methylsulfanyl)butane)), two lipid oxidation products (1-octen-3-one and trans-4,5-epoxy-(2E)-dec-2-enal), and 2-isopropyl-3-methoxypyrazine. Among these, the sulfur compounds contributed most to the overall smell of the raw and cooked vegetables. The quantitation anal. indicates that the eight odorants are the backbone compounds for raw and cooked kohlrabi. The OAVs for the backbone compounds and also for minor odorants are clearly higher in raw kohlrabi than in the cooked one. Differences can be explained by the influence of the cooking process. In the experiment, the researchers used many compounds, for example, 5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7Product Details of 695-06-7).

5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 695-06-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lewis Acid-Catalyzed Synthesis of Benzofurans and 4,5,6,7-Tetrahydrobenzofurans from Acrolein Dimer and 1,3-Dicarbonyl Compounds was written by Huang, Wenbo;Xu, Jing;Liu, Changhui;Chen, Zhiyan;Gu, Yanlong. And the article was included in Journal of Organic Chemistry in 2019.Recommanded Product: 13669-10-8 This article mentions the following:

2,3-Disubstituted benzofurans such as benzofurandicarboxylate I were prepared by cyclocondensation of acrolein dimer (2H-3,4-dihydro-2-pyrancarboxaldehyde) and 1,3-dicarbonyl compounds, particularly 灏?ketoesters and 1,3-diketones, in the presence of Lewis acid catalysts [either AlCl₃ or Sc(OTf)₃ or in one case, BF₃璺疎t₂O] using N-bromosuccinimide (NBS) as an oxidant. The method was used to prepare benzbromarone and amiodarone. An oxobutylfurancarboxylate intermediate in the cyclocondensation of acrolein dimer and Me acetoacetate was isolated; cyclocondensation with indoles, 1,2,4-trimethoxybenzene, and 1,1-diphenylethylene yielded aryl- and diphenylvinyl-substituted tetrahydrobenzofurancarboxylates such as II [R = 3-indolyl, 1-methyl-3-indolyl, 2,4,5-(MeO)₃C₆H₂, Ph₂C:CH]. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Recommanded Product: 13669-10-8).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 13669-10-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

One-Pot Tandem Michael Addition/Enantioselective Conia-Ene Cyclization Mediated by Chiral Iron(III)/Silver(I) Cooperative Catalysis was written by Horibe, Takahiro;Sakakibara, Masato;Hiramatsu, Rin;Takeda, Kazuki;Ishihara, Kazuaki. And the article was included in Angewandte Chemie, International Edition in 2020.Reference of 13669-10-8 This article mentions the following:

The first one-pot tandem Michael addition/enantioselective Conia-ene cyclization of N-protected prop-2-yn-1-amines with 2-methylene-3-oxoalkanoates promoted by chiral iron(III)/silver(I) cooperative catalysts was developed. Alkyl 4-methylenepyrrolidine-3-acyl-3-carboxylates, which can be transformed into 灏?proline derivatives, were obtained in high yield with high enantioselectivity. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Reference of 13669-10-8).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 13669-10-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Electrochemical Oxidative Cyclization: Synthesis of Polysubstituted Pyrrole from Enamines was written by Chen, Zhiwei;Shi, Guang;Tang, Wei;Sun, Jie;Wang, Wenxing. And the article was included in European Journal of Organic Chemistry in 2021.Category: esters-buliding-blocks This article mentions the following:

A conceptually novel method for the preparation of pyrrole is described by electrochem.-oxidation-induced intermol. annulation via enamines. In a simple undivided cell, based on a sodium acetate-facilitated, polysubstituted pyrrole derivations has been facilely synthesized under external oxidant-free condition. This electrosynthetic approach providing an environmentally benign protocol for C-C bond cross-coupling and oxidative annulation, which features unparalleled broad scope of substrates and practicality. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Category: esters-buliding-blocks).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Phytotoxic activity of Moldavian dragonhead (Dracocephalum moldavica L.) essential oil and its possible use as bio-herbicide was written by Pouresmaeil, Mohammad;Sabzi-Nojadeh, Mohsen;Movafeghi, Ali;Aghbash, Behzad Nezhadasad;Kosari-Nasab, Morteza;Zengin, Gokhan;Maggi, Filippo. And the article was included in Process Biochemistry (Oxford, United Kingdom) in 2022.Application In Synthesis of (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate This article mentions the following:

The incessant use of synthetic herbicides may cause several ecol. problems including environmental contamination and developing herbicide-resistant species. These concerns led to exploring new eco-friendly weed control strategies. Present study is aimed to assess the phytotoxic activity of Moldavian dragonhead, Dracocephalum moldavica L., essential oil (EO) on Bromus tectorum L. All experiments were carried out as a completely randomized design with three replications. The EO of D. moldavica was analyzed using gas chromatog. coupled with mass spectrometry (GC-MS). The outcomes of GC-MS showed that geranyl acetate (32.57%), geranial (24.50%), neral (22.65%), and geraniol (8.78%) are the major bioactive compounds of EO. As a result of treatment of B. tectorum with EO, seed germination and plantlet growth parameters were reduced in a concentration-dependent manner, and were completely suppressed with an essential oil concentration of 2娓璍/mL. The content of pigments was also reduced in a dose-dependent manner. Although, antioxidant enzymes activities were enhanced in low concentrations of the EO, they were inhibited in high concentrations especially at 2娓璍/mL. H2O2 and malondialdehyde content as well as electrolyte leakage were enhanced with the increasing concentration of EO. Overall, the outcomes of present study suggest that essential oil of D. moldavica can be used industrially to develop bio-herbicides owing to its noteworthy phytotoxic activity and weed killer potential. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Application In Synthesis of (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 绾?valerolactone.Application In Synthesis of (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

One pot cascade synthesis of fused heterocycles from furan-tethered terminal alkynes and aldehydes in the presence of amines and CuBr was written by Zhang, Yan-Yan;Hao, Jian;Shi, Min. And the article was included in Organic Chemistry Frontiers in 2015.Recommanded Product: 17920-23-9 This article mentions the following:

A one-pot protocol for the construction of complex heterocycles through furan-tethered terminal alkynes, aldehydes, amines and CuBr upon heating was developed, giving the cycloadducts in moderate to high yields along with moderate to good regioselectivities. The reactions proceed through a two-component domino reaction, including allenation and subsequent intramol. Diels-Alder reaction. A wide range of aliphatic or aromatic aldehydes and furan-tethered terminal alkynes were well-tolerated, enriching the chem. of the intramol. Diels-Alder reaction related to furan. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Recommanded Product: 17920-23-9).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 17920-23-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Porphyrins. VI. The relative reactivities of substituted pyrroles was written by Badger, G. M.;Harris, R. L. N.;Jones, R. Alan. And the article was included in Australian Journal of Chemistry in 1964.Formula: C8H11NO2 This article mentions the following:

The comparative reactivities of a series of substituted pyrroles was examined by use of the diazo-coupling reaction and the Ehrlich reaction. The method used was that of Treibs and Fritz (CA 52, 13705g), but some modifications were introduced, p-AcNHC₆H₄N₂Cl was used instead of p-PhNHC₆H₄N₂Cl, and PhN₂Cl and 2,4,6-Br₃C₆H₂N₂OAc were included to improve the accuracy of classification. Six aryldiazonium salts (I-VI) were used. With I-IV the reaction was carried out by mixing an alc. solution of the pyrrole (5 mL. 1.5 鑴?10^-3M) with an aqueous solution of the diazonium salt (0.15 mL., 5 鑴?10^-2M) and with V-VI an HOAc solution of the pyrrole was mixed with an HOAc solution of the Na salt of the anti-diazotate, both with and without the addition of HCl (0.15 mL., 2N). Tests were carried out at pH 3, 5, and 7 with the following pyrroles (substituents given): 3-Me; 2,4-Me₂; 3-CO₂Et; 2,4-Me₂, 3-CO₂Et; 2-Z, 3-Me, 4-CO₂Et; 2-Q, 3-Me, 4-Ac; 3-CO₂Et, 4-Me; 3-Ac, 4-Me; 2-CO₂Et, 3,4-Me₂; 2-CO₂Et, 3,5-Me₂; 2-CO₂Et, 3,5-Me₂; 2-CO₂Et, 3-CH₂CH₂CO₂Et, 5-Me; 2-CO₂Et; 2-CH:C(CN)₂, 3,4-Me₂; 2-CH:C(CN)₂, 3-CH₂CH₂-CO₂Et, 4-Me; 2-CH:C(CN)₂, 4-Me; 2-CH:C(CN)₂, 3-Me; and 2-CH:C(CN)₂. The results showed that the dicyanovinyl group exerted a very pronounced deactivating influence on pyrroles. The dicyanovinyl group was much more deactivating than an ethoxycarbonyl group. Most of the pyrroles used were prepared earlier. Other pyrroles were prepared as follows: A solution of 50 g. 2-carboxy-3-ethoxycarbonyl-4-methylpyrrole in ethanol-amine was refluxed 1 h. and poured into 1 l. H₂O, the mixture extracted 24 h. with ether, and the aqueous solution acidified with dilute HCl to give 36 g. 2-carboxy-3-(2-hydroxyethylcarbonyl)-4-methylpyr-role (VII), m. 219鎺?(decomposition) (EtOH). VII (2.5 g.) in 10 mL. 25% aqueous NaOH was heated 15 h. in a sealed tube at 140-50鎺? the mixture extracted with ether, and the extract dried and evaporated to yield 0.67 g. 3-methylpyrrole (VIII), b. 142-3鎺? Formylation of VIII by the Vilsmeier-Haack method at 0鎺?yielded 2-formyl-3-methylpyrrole (IX), m. 92鎺? Condensation of 0.1 g. IX with 0.05 g. malononitrile in a few drops MeOH and I drop Et₂NH yielded 2-(-dicyanovinyl)-3-methylpyrrole, m. 194.5-5.5鎺?(decomposition) (MeOH). A mixture of 1 g. 2-ethoxycarbonyl-3,4-dimethylpyrrole, 1 mL. EtOH, and 10 mL. 10% aqueous KOH was refluxed 90 min. and the solution cooled and brought to pH 5-6 (HOAc) to yield 0.8 g. 2-carboxy-3,4-dimethylpyrrole (X). Refluxing 5 g. X and 5 mL. ethanolamine 1 h. and working up the mixture yielded 2.56 g. 3,4-dimethylpyrrole (XI), b₇₆₀ 164-6鎺? m. 32-3鎺? Formylation of XI (as in VIII) yielded 2-formyl-3,4-dimethylpyrrole (XII), m. 129-30鎺? XII was converted into 2-(-dicyanovinyl)-3,4-dimethylpyrrole by the method of Fischer and Hoefelman (CA 32, 3389₄). In the experiment, the researchers used many compounds, for example, Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7Formula: C8H11NO2).

Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Formula: C8H11NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of isomeric 3-aminopyridopyrimidin-4(3H)ones was written by Stanovnik, B.;Tisler M.. And the article was included in Croatica Chemica Acta in 1972.Quality Control of Methyl 2-aminonicotinate This article mentions the following:

Structural assignments of the title compounds (I, II) obtained from H2NNH2 and III or IV resp. were achieved by chem. evidence and interpretation of ir, NMR and mass spectra. III and IV (R1 = CO2Et, CN) were prepared from esters of 2-aninopyridine-3-carboxylic (V) or 3-aminopyridine-2-carboxylic acids (VI) by heating with diethyl ethoxymethylene malonate or ethyl ethoxymethylenecyanacetate (VII). The ratio of cis:trans isomers in III (R1 = CN) prepared from V and VII was (NMR) 閳?:2. Treatment of III or IV with excess H2NNH2H2O in EtOH at room temperature gave I (R = NH2), or II (R = NH2) resp. I and II (R = NH2) were also obtainable from the condensation products of V or VI with Me2NCH(OMe)2 followed by a similar treatment with H2NNH2H2O. 2-Aminonicotinic acid hydrazide and diethoxymethyl acetate cyclized into I (R = N:CHOEt) which upon hydrolysis gave I (R = NH2). Treatment of I or II (R = NH2) with amyl nitrite gave I (R = H), which was treated with AC2O-pyridine to give I or II (R = NHAc) especially Condensation of V with cis- trans-2,5-diethoxy-tetrahydrofuran in AcOH under reflux gave 3-carbomethoxy-2-(N-pyrrolo)pyridine, which with polyphosphoric acid underwent pyrrole elimination to give methyl 2-aminopyridine-3-carboxylate. In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1Quality Control of Methyl 2-aminonicotinate).

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Quality Control of Methyl 2-aminonicotinate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Flavor components in tobacco capsules identified through non-targeted quantitative analysis was written by Lim, Hyun-Hee;Choi, Kyeong-Yun;Shin, Ho-Sang. And the article was included in Journal of Mass Spectrometry in 2022.Related Products of 659-70-1 This article mentions the following:

Tobacco flavors increase the attractiveness of a tobacco brand and ultimately promote addiction. Information about what flavor and how much flavor is in flavor capsules can provide an effective way to regulate tobacco flavor. In this study, 128 flavor chems. were identified and quantified by gas chromatog.-mass spectrometry using libraries and authentic standards Validation of the developed method was performed for interference, detection limits, calibration curves, accuracy, and precision. Menthol was the main ingredient in all capsules, and the carcinogenic pulegone was detected. Detected menthofuran, benzyl alc., geraniol, and eugenol cause toxic or severe irritation, and detected lactones can increase nicotine addiction by inhibiting nicotine metabolism in smokers. Margin of exposures for carcinogenic pulegone and non-carcinogenic menthol were well below safety thresholds, indicating a significant risk of inhalation exposure. It is desirable to prohibit the use of flavor capsules in consideration of human risk. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Related Products of 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Characterization of aroma-active compounds in Jasminum sambac concrete by aroma extract dilution analysis and odour activity value was written by Zhang, Jinglin;Li, Juan;Wang, Juan;Sun, Baoguo;Liu, Yuping;Huang, Mingquan. And the article was included in Flavour and Fragrance Journal in 2021.Recommanded Product: Ethyl 2-hydroxybenzoate This article mentions the following:

Jasminum sambac is a flower and usually used in food, cosmetics or other chem. industries for its unique flavor characteristics in China. However, mol. sensory technologies have not applied to identify aroma-active compounds in J sambac concrete. In this study, gas chromatog.-olfactometry (GC-O), gas chromatog.-mass spectrometry and solvent-assisted flavor evaporation were applied to isolate the odorants in three Chinese J sambac concrete (E1, E2 and E3) obtained from different companies. A total of forty-nine, forty-eight, thirty-nine odorants were screened by GC-O with aroma extract dilution anal. in E1, E2 and E3, resp. The higher flavor dilution (FD) factors were linalool (19 683-59 049, floral), Me anthranilate (6561-19 683, grape-like) and benzyl acetate (2187-19 683, floral). Twenty-two aroma compounds were quantitated by gas chromatog.-flame ionization detection with internal standard, and then their odor activity values were obtained. Linalool, cis-3-hexenyl acetate, linalyl acetate, eugenol and Me salicylate contributed greatly to the aroma of J sambac concretes. The aroma recombination model was established by mixing twenty-two key odorants based on their measured concentrations, and the result revealed that the overall aroma profile was similar to that of the original sample. These results proved basic data for improvement of the national standard of jasmine concrete. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxybenzoate (cas: 118-61-6Recommanded Product: Ethyl 2-hydroxybenzoate).

Ethyl 2-hydroxybenzoate (cas: 118-61-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Recommanded Product: Ethyl 2-hydroxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics