Tag: 100-200

Olefin-Oriented Selective Synthesis of Linear and Branched N-Alkylated Heterocycles by Hydroamination was written by Sushmita;Aggarwal, Trapti;Saini, Kapil Mohan;Verma, Akhilesh K.. And the article was included in European Journal of Organic Chemistry in 2020.Formula: C4H7NS The following contents are mentioned in the article:

An effective base-induced selective approach for the synthesis of linear and branched N-alkylated heterocycles by hydroamination of olefins has been described. The designed C-N bond formation method was directed through the olefin, as with styrenes only linear N-alkylated product was obtained, and acrylates gave linear as well as branched alkylated heterocycles. This protocol provided the synthesis of exclusive N-alkylated product instead of the C-3 Michael addition product. The reaction was also compatible with Ph vinyl sulfone, thus leading to the formation of sulfone substituted heterocycles in good yield. Further, the method was utilized for the synthesis of medicinally important analogs of CB1 Cannabinoid receptor and Dimebon analog in short reaction sequence. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Formula: C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Formula: C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Olefin-Oriented Selective Synthesis of Linear and Branched N-Alkylated Heterocycles by Hydroamination was written by Sushmita;Aggarwal, Trapti;Saini, Kapil Mohan;Verma, Akhilesh K.. And the article was included in European Journal of Organic Chemistry in 2020.Formula: C4H7NS The following contents are mentioned in the article:

An effective base-induced selective approach for the synthesis of linear and branched N-alkylated heterocycles by hydroamination of olefins has been described. The designed C-N bond formation method was directed through the olefin, as with styrenes only linear N-alkylated product was obtained, and acrylates gave linear as well as branched alkylated heterocycles. This protocol provided the synthesis of exclusive N-alkylated product instead of the C-3 Michael addition product. The reaction was also compatible with Ph vinyl sulfone, thus leading to the formation of sulfone substituted heterocycles in good yield. Further, the method was utilized for the synthesis of medicinally important analogs of CB1 Cannabinoid receptor and Dimebon analog in short reaction sequence. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Formula: C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Formula: C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pd(II)-catalyzed acetalization of terminal olefins with electron-withdrawing groups in supercritical carbon dioxide: selective control and mechanism was written by Wang, Zhao-Yang;Jiang, Huan-Feng;Ouyang, Xiao-Yue;Qi, Chao-Rong;Yang, Shao-Rong. And the article was included in Tetrahedron in 2006.Safety of Ethyl 3-ethoxypropanoate The following contents are mentioned in the article:

Pd(II)-catalyzed acetalization of terminal olefins with electron-withdrawing groups was carried out smoothly in supercritical CO₂ under O atm. when polystyrene-supported benzoquinone (PS-BQ) or Cu^II (Cu^I) chloride was employed as cocatalyst. The higher selectivity was achieved, without any chlorinated byproduct detected, when using PS-BQ instead of Cu^II (or Cu^I) chloride. PS-BQ could be recycled with excellent catalytic activity remaining after each simple filtration. Cl ion is a promoter. The different acetalization mechanisms were revealed by the subtle relation of Cl ion and benzoquinone (BQ) to the catalytic activity of PdCl₂/PS-BQ, Pd^II-CuCl₂ or Pd(OAc)₂/PS-BQ. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Safety of Ethyl 3-ethoxypropanoate).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of Ethyl 3-ethoxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Identifying new lead structures to enhance tolerance towards drought stress via high-throughput screening giving crops a quantum of solace was written by Frackenpohl, Jens;Schneider, Linn;Decker, Luka J. B.;Dittgen, Jan;Fenkl, Franz;Fischer, Christian;Franke, Jana;Freigang, Joerg;Getachew, Rahel;Gonzalez Fernandez-Nino, Susana M.;Helmke, Hendrik;Hills, Martin J.;Hohmann, Sabine;Kleemann, Jochen;Kurowski, Karoline;Lange, Gudrun;Luemmen, Peter;Meyering, Nicole;Poree, Fabien;Schmutzler, Dirk;Wrede, Sebastian. And the article was included in Bioorganic & Medicinal Chemistry in 2019.SDS of cas: 2253-73-8 The following contents are mentioned in the article:

Novel synthetic lead structures interacting with RCAR/(PYR/PYL) receptor proteins were identified based on the results of a high-throughput screening campaign of a large compound library followed by focused SAR studies of the three most promising hit clusters. While indolinylmethyl sulfonamides 8y,z and phenylsulfonyl ethylenediamines 9y,z showed strong affinities for RCAR/ (PYR/PYL) receptor proteins in wheat, thiotriazolyl acetamides 7f,s exhibited promising efficacy against drought stress in vivo (wheat, corn and canola) combined with confirmed target interaction in wheat and arabidopsis thaliana. Remarkably, binding affinities of several representatives of 8 and 9 were on the same level or even better than the essential plant hormone abscisic acid (ABA). This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8SDS of cas: 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.SDS of cas: 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Identifying new lead structures to enhance tolerance towards drought stress via high-throughput screening giving crops a quantum of solace was written by Frackenpohl, Jens;Schneider, Linn;Decker, Luka J. B.;Dittgen, Jan;Fenkl, Franz;Fischer, Christian;Franke, Jana;Freigang, Joerg;Getachew, Rahel;Gonzalez Fernandez-Nino, Susana M.;Helmke, Hendrik;Hills, Martin J.;Hohmann, Sabine;Kleemann, Jochen;Kurowski, Karoline;Lange, Gudrun;Luemmen, Peter;Meyering, Nicole;Poree, Fabien;Schmutzler, Dirk;Wrede, Sebastian. And the article was included in Bioorganic & Medicinal Chemistry in 2019.Synthetic Route of C4H7NS The following contents are mentioned in the article:

Novel synthetic lead structures interacting with RCAR/(PYR/PYL) receptor proteins were identified based on the results of a high-throughput screening campaign of a large compound library followed by focused SAR studies of the three most promising hit clusters. While indolinylmethyl sulfonamides 8y,z and phenylsulfonyl ethylenediamines 9y,z showed strong affinities for RCAR/ (PYR/PYL) receptor proteins in wheat, thiotriazolyl acetamides 7f,s exhibited promising efficacy against drought stress in vivo (wheat, corn and canola) combined with confirmed target interaction in wheat and arabidopsis thaliana. Remarkably, binding affinities of several representatives of 8 and 9 were on the same level or even better than the essential plant hormone abscisic acid (ABA). This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Synthetic Route of C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Synthetic Route of C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

GC-MS determination of residual amounts of volatile organic compounds in solidified paint with accelerated solvent extraction was written by Ma, Teng-zhou;Chen, Jun-shui;Cheng, Yu-xiao;Ma, Ming;Zhang, Lin;Shen, Bo. And the article was included in Lihua Jianyan, Huaxue Fence in 2013.Computed Properties of C7H14O3 The following contents are mentioned in the article:

Residual amounts of 7 volatile organic compounds, i.e., toluene, ethylbenzene, xylene, hexamethylacetone, 3-ethoxypropionate, 6-methyl-2-heptanone and benzylalc. in solidified paint were determined by GC-MS. The sample was crushed and extracted (by ASE) thrice with acetone consecutively, at 50°C for 3 min in each extraction HP-5MS column was used for separation Linear relationships between values of peak area and mass concentration of the 7 volatile organic compounds were kept in definite ranges, with detection limits (3S/N) in the range of 0.01-1.35μg. Using blank sample as matrix, test for recovery was made by standard addition method, and values of recovery obtained were in the range of 84.4%-104%, with values of RSD’s (n = 6) in the range of 0.80%-13%. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Computed Properties of C7H14O3).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Computed Properties of C7H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ruthenium-catalyzed hydrogenation of CO₂ as a route to methyl esters for use as biofuels or fine chemicals was written by Wang, Zheng;Zhao, Ziwei;Li, Yong;Zhong, Yanxia;Zhang, Qiuyue;Liu, Qingbin;Solan, Gregory A.;Ma, Yanping;Sun, Wen-Hua. And the article was included in Chemical Science in 2020.Recommanded Product: Methyl heptanoate The following contents are mentioned in the article:

A novel robust diphosphine-ruthenium(II) complex has been developed that can efficiently catalyze both the hydrogenation of CO₂ to methanol and its in situ condensation with carboxylic acids to form Me esters; a TON of up to 3260 is achievable for the CO₂ to methanol step. Both aromatic and aliphatic carboxylic acids can be transformed to their corresponding Me esters with high conversion and selectivity (17 aliphatic and 18 aromatic examples). On the basis of a series of experiments, a mechanism has been proposed to account for the various steps involved in the catalytic pathway. More importantly, this approach provides a promising route for using CO₂ as a C1 source for the production of biofuels, fine chems. and methanol. This study involved multiple reactions and reactants, such as Methyl heptanoate (cas: 106-73-0Recommanded Product: Methyl heptanoate).

Methyl heptanoate (cas: 106-73-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: Methyl heptanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Novel photoacid generators for chemically amplified resists was written by Asakura, Toshikage;Yamato, Hitoshi;Matsumoto, Akira;Murer, Peter;Ohwa, Masaki. And the article was included in Journal of Photopolymer Science and Technology in 2003.Safety of Ethyl 3-ethoxypropanoate The following contents are mentioned in the article:

Recently the authors developed new class of non-ionic oxime sulfonate PAG. The compounds generate various kinds of sulfonic acids, such as n-propane, n-octane, camphor and p-toluene sulfonic acid under deep-UV exposure and trifluoromethanesulfonic acid under ArF exposure and are applicable for the corresponding chem. amplified (CA) photoresists. The application-relevant properties of the compounds such as solubility in propylene glycol monomethyl ether acetate (PGMEA), Et lactate, Et 3-ethoxypropionate, and 2-heptanone, UV absorption, thermal stability with or without poly(4-hydroxystyrene) (PHS), volatility, performance in model resist formulations were evaluated. In addition, the microlithog. simulation based on the results of DRM results of the trifluoromethanesulfonate was also studied. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Safety of Ethyl 3-ethoxypropanoate).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Safety of Ethyl 3-ethoxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Environment-friendly and efficient synthesis of 2-aminobenzo-oxazoles and 2-aminobenzothiazoles catalyzed by Vitreoscilla hemoglobin incorporating a cobalt porphyrin cofactor was written by Xu, Yaning;Li, Fengxi;Zhao, Nan;Su, Jiali;Wang, Chunyu;Wang, Ciduo;Li, Zhengqiang;Wang, Lei. And the article was included in Green Chemistry in 2021.Synthetic Route of C4H7NS The following contents are mentioned in the article:

In this study, an environment-friendly and efficient artificial Vitreoscilla Hb (VHb) for the synthesis of 2-aminobenzoxazoles and 2-aminobenzothiazoles has been reported. Authors demonstrate an expression-based porphyrin substitution strategy to produce VHb containing cobalt porphyrin instead of native hemin, which can catalyze the oxidative cyclization of corresponding 2-aminobenzoxazoles and 2-aminobenthiazoles with up to 97% yield and 4850 catalytic turnovers in water under aerobic conditions. Hence, authors provide a green and mild method for the synthesis of 2-aminobenzoxazoles and 2-aminobenzothiazoles. In addition, authors indicate the value of porphyrin ligand substitution as a strategy to tune and enhance the catalytic properties of hemoproteins in non-natural reactions. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Synthetic Route of C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Environment-friendly and efficient synthesis of 2-aminobenzo-oxazoles and 2-aminobenzothiazoles catalyzed by Vitreoscilla hemoglobin incorporating a cobalt porphyrin cofactor was written by Xu, Yaning;Li, Fengxi;Zhao, Nan;Su, Jiali;Wang, Chunyu;Wang, Ciduo;Li, Zhengqiang;Wang, Lei. And the article was included in Green Chemistry in 2021.Safety of Isopropylisothiocyanate The following contents are mentioned in the article:

In this study, an environment-friendly and efficient artificial Vitreoscilla Hb (VHb) for the synthesis of 2-aminobenzoxazoles and 2-aminobenzothiazoles has been reported. Authors demonstrate an expression-based porphyrin substitution strategy to produce VHb containing cobalt porphyrin instead of native hemin, which can catalyze the oxidative cyclization of corresponding 2-aminobenzoxazoles and 2-aminobenthiazoles with up to 97% yield and 4850 catalytic turnovers in water under aerobic conditions. Hence, authors provide a green and mild method for the synthesis of 2-aminobenzoxazoles and 2-aminobenzothiazoles. In addition, authors indicate the value of porphyrin ligand substitution as a strategy to tune and enhance the catalytic properties of hemoproteins in non-natural reactions. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Safety of Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Safety of Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics