Tag: 100-200

Gram Scalable Method to Synthesize Biscarbodiimides and Asymmetric Monocarbodiimides: A Platform to Access an Array of Phosphaguanidines, Amidines, and Guanidines was written by Camelio, Andrew M.;Krasovskiy, Arkady;Bailey, Brad;Davis, Anna. And the article was included in Journal of Organic Chemistry in 2022.Quality Control of Isopropylisothiocyanate The following contents are mentioned in the article:

A mild, broadly functional group tolerant methodol. has been developed to access a variety of mono- and bis-carbodiimides RN=C=NR¹ (R = i-Pr, cyclohexyl, adamantan-1-yl, etc.; R¹ = Bn, cyclohexyl) and RN=C=N(CH₂)₅N=C=NR in good yield and high purity on multigram scale. Direct addition into these versatile motifs facilitated the rapid synthesis of a library of novel amidinines, guanidines, and phosphaguanidines RNHC(R²)=NR¹ (R² = diphenylphosphanyl, 9H-carbazol-9-yl, diethylaminyl, etc.) and RN=C(R²)NH(CH₂)_nNHC(R²)=NR (n = 4, 5). This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Quality Control of Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Quality Control of Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gram Scalable Method to Synthesize Biscarbodiimides and Asymmetric Monocarbodiimides: A Platform to Access an Array of Phosphaguanidines, Amidines, and Guanidines was written by Camelio, Andrew M.;Krasovskiy, Arkady;Bailey, Brad;Davis, Anna. And the article was included in Journal of Organic Chemistry in 2022.Safety of Isopropylisothiocyanate The following contents are mentioned in the article:

A mild, broadly functional group tolerant methodol. has been developed to access a variety of mono- and bis-carbodiimides RN=C=NR¹ (R = i-Pr, cyclohexyl, adamantan-1-yl, etc.; R¹ = Bn, cyclohexyl) and RN=C=N(CH₂)₅N=C=NR in good yield and high purity on multigram scale. Direct addition into these versatile motifs facilitated the rapid synthesis of a library of novel amidinines, guanidines, and phosphaguanidines RNHC(R²)=NR¹ (R² = diphenylphosphanyl, 9H-carbazol-9-yl, diethylaminyl, etc.) and RN=C(R²)NH(CH₂)_nNHC(R²)=NR (n = 4, 5). This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Safety of Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Safety of Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Alkoxycarbonylation of olefins with carbon dioxide by a reusable heterobimetallic ruthenium-cobalt catalytic system was written by Zhang, Xuehua;Shen, Chaoren;Xia, Chungu;Tian, Xinxin;He, Lin. And the article was included in Green Chemistry in 2018.Computed Properties of C8H16O2 The following contents are mentioned in the article:

The heterobimetallic ruthenium-cobalt catalytic system exhibited good catalytic performance and reusability in the reductive alkoxycarbonylation of olefins with carbon dioxide. Compared to the previous system only consisting of ruthenium catalyst, the binary catalyst system effectively reduced the usage of noble metal and ionic liquid additives. The resp. contribution of ruthenium and cobalt catalysts in this multiple-step catalytic process was investigated by a series of condition-controlled experiments The evolution of the ruthenium catalyst and the occurrence of alkene hydrogenation during the reaction was explained by theortical calculations This study involved multiple reactions and reactants, such as Methyl heptanoate (cas: 106-73-0Computed Properties of C8H16O2).

Methyl heptanoate (cas: 106-73-0) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Computed Properties of C8H16O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Transition-State Expansion: A Quantitative Model for Counterion Effects in Ionic Reactions was written by Han, Junbin;Lu, Zhichao;Hammond, Gerald B.;Xu, Bo. And the article was included in iScience in 2020.Application of 112-14-1 The following contents are mentioned in the article:

Ionic reactions are the most common reactions used in chem. synthesis. In relatively low dielec. constant solvents (e.g., dichloromethane, toluene), ions usually exist as ion pairs. Despite the importance of counterions, a quant. description of how the paired ‘counterion’ affects the reaction kinetic is still elusive. We introduce a general and quant. model, namely transition-state expansion (TSE), that describes how the size of a counterion affects the transition-state structure and the kinetics of an ionic reaction. This model could rationalize the counterion effects in nucleophilic substitutions and gold-catalyzed enyne cycloisomerizations. This study involved multiple reactions and reactants, such as Octyl acetate (cas: 112-14-1Application of 112-14-1).

Octyl acetate (cas: 112-14-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 112-14-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Access to 3-Amino-[1,2,4]-triazolo Pyridines and Related Heterocycles via Electrochemically Induced Desulfurative Cyclization was written by Hu, Yunfei;Chen, Li;Zou, Canlin;He, Jiangtao;Feng, Luanqi;Wu, Jia-Qiang;Chen, Wen-Hua;Hu, Jinhui. And the article was included in Organic Letters in 2022.Reference of 2253-73-8 The following contents are mentioned in the article:

An efficient, one-pot approach was established for synthesizing a wide range of 3-amino-[1,2,4]-triazolo pyridines and related heterocycles from the electrochem. induced desulfurative cyclization of 2-hydrazinopyridines with isothiocyanates. The protocol allowed for the formation of C-N bonds under simple conditions without transition metals or external oxidants. The practicability of this strategy was demonstrated by its broad substrate scope, good functional group compatibility, and gram-scale synthesis. The late-stage modification of 3-amino-[1,2,4]-triazolo pyridines enabled to obtain several mols. with potent anticancer activity. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Reference of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Reference of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Access to 3-Amino-[1,2,4]-triazolo Pyridines and Related Heterocycles via Electrochemically Induced Desulfurative Cyclization was written by Hu, Yunfei;Chen, Li;Zou, Canlin;He, Jiangtao;Feng, Luanqi;Wu, Jia-Qiang;Chen, Wen-Hua;Hu, Jinhui. And the article was included in Organic Letters in 2022.Product Details of 2253-73-8 The following contents are mentioned in the article:

An efficient, one-pot approach was established for synthesizing a wide range of 3-amino-[1,2,4]-triazolo pyridines and related heterocycles from the electrochem. induced desulfurative cyclization of 2-hydrazinopyridines with isothiocyanates. The protocol allowed for the formation of C-N bonds under simple conditions without transition metals or external oxidants. The practicability of this strategy was demonstrated by its broad substrate scope, good functional group compatibility, and gram-scale synthesis. The late-stage modification of 3-amino-[1,2,4]-triazolo pyridines enabled to obtain several mols. with potent anticancer activity. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Product Details of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Product Details of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides in the synthesis of a new heterocyclic [1,2,3]triazolo[4,5-e][1,4]thiazepine system was written by Syrota, Natalia A.;Kemskiy, Sergiy V.;Bol’but, Andriy V.;Chernobaev, Igor I.;Liavinets, Oleksandr S.;Vovk, Mykhailo V.. And the article was included in Chemistry of Heterocyclic Compounds in 2021.Reference of 2253-73-8 The following contents are mentioned in the article:

4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides I [R¹ = Me, Ph, 2-MeOC₆H₄, H₂CH₂CPh; R² = Et, i-Pr, t-Bu, cyclohexyl] , obtained by a sequential treatment of 4-(N-Boc-amino)-1H-1,2,3-triazoles with n-BuLi and alkyl isothiocyanates at -78 and -60°C, reacted with Et bromoacetate, forming the resp. 4-(N-Boc-amino)-5-thioimidates II , which underwent intramol. cyclocondensation upon treatment in saturated HCl solution in dioxane, producing 8-(alkylimino)-4,8-dihydro-1H-[1,2,3]triazolo[4,5-e][1,4]thiazepin-5(6H)-ones III. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Reference of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides in the synthesis of a new heterocyclic [1,2,3]triazolo[4,5-e][1,4]thiazepine system was written by Syrota, Natalia A.;Kemskiy, Sergiy V.;Bol’but, Andriy V.;Chernobaev, Igor I.;Liavinets, Oleksandr S.;Vovk, Mykhailo V.. And the article was included in Chemistry of Heterocyclic Compounds in 2021.Synthetic Route of C4H7NS The following contents are mentioned in the article:

4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides I [R¹ = Me, Ph, 2-MeOC₆H₄, H₂CH₂CPh; R² = Et, i-Pr, t-Bu, cyclohexyl] , obtained by a sequential treatment of 4-(N-Boc-amino)-1H-1,2,3-triazoles with n-BuLi and alkyl isothiocyanates at -78 and -60°C, reacted with Et bromoacetate, forming the resp. 4-(N-Boc-amino)-5-thioimidates II , which underwent intramol. cyclocondensation upon treatment in saturated HCl solution in dioxane, producing 8-(alkylimino)-4,8-dihydro-1H-[1,2,3]triazolo[4,5-e][1,4]thiazepin-5(6H)-ones III. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Synthetic Route of C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Synthetic Route of C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Density and Viscosity for Ethyl 3-Ethoxypropionate + Methacrylic Acid, + Benzyl Methacrylate, and + 2-Hydroxyethyl Methacrylate was written by Chen, Jui-Tang;Chang, Wong-Chao. And the article was included in Journal of Chemical and Engineering Data in 2005.Recommanded Product: 763-69-9 The following contents are mentioned in the article:

Densities and viscosities of binary mixtures of Et 3-ethoxypropionate with methacrylic acid, benzyl methacrylate, and 2-hydroxyethyl methacrylate were measured at (298.15, 308.15, and 318.15) K over the entire composition range. A pycnometer and a Cannon-Fenske routine viscometer were used to determine d. and kinematic viscosity, resp. The excess molar volumes (V^E) and viscosity deviations (δη) were calculated at various temperatures A Redlich-Kister type polynomial was applied to fit the isothermal excess volumes and viscosity deviations, and McAllister’s three-body and four-body interaction models were also used to correlate the kinematic viscosities. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Recommanded Product: 763-69-9).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 763-69-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Selective syntheses of aliphatic carboxylic acids, esters, and amides using sodium tetracarbonylferrate(-II) was written by Collman, James P.;Winter, Stanley R.;Komoto, Robert G.. And the article was included in Journal of the American Chemical Society in 1973.Application In Synthesis of Ethyl methyl adipate The following contents are mentioned in the article:

New routes have been developed for the conversion of alkyl halides and tosylates into carboxylic acids, esters, and amides using sodium tetracarbonylferrate(-II). Carboxylic acids are obtained from alkyl or acyl tetracarbonylferrate(0) intermediates using O2, NaClO, or I2/H2O. Esters and amides are obtained from the same intermediates using I2/ROH and I2/RR’NH resp. Advantages of these syntheses lie in their selectivity between halides and in their toleration of a wide range of functional groups including carbonyl groups. In addition, it is likely that the stereospecificity observed in one of our earlier ketone synthesis will be also found in these reactions. This study involved multiple reactions and reactants, such as Ethyl methyl adipate (cas: 18891-13-9Application In Synthesis of Ethyl methyl adipate).

Ethyl methyl adipate (cas: 18891-13-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application In Synthesis of Ethyl methyl adipate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics