Tag: 100-200

A New Facet of Azatriene Reactivity: A Short Cut to 5-Amino-3-methyl-4-(1H-pyrrol-1-yl)thiophene-2-carboxylates and 5-Amino-3-methyl-4-(1H-pyrrol-1-yl)thiophene-2-carbonitriles was written by Nedolya, Nina A.;Tarasova, Olga A.;Albanov, Alexander I.;Trofimov, Boris A.. And the article was included in European Journal of Organic Chemistry in 2018.HPLC of Formula: 2253-73-8 The following contents are mentioned in the article:

An simple and expedient approach to highly functionalized tetrasubstituted thiophenes from readily accessible starting materials [(1H-pyrrol-1-yl)allene, isothiocyanates, and alkyl 2-bromoacetates or 2-bromoacetonitrile] has been developed. The method is based on the one-pot synthesis and fast in-situ cyclization of alkyl 2-{[2-(1H-pyrrol-1-yl)buta-2,3-dienimidoyl]sulfanyl}acetates or cyanomethyl 2-(1H-pyrrol-1-yl)buta-2,3-dienimidothioates (1-aza-1,3,4-trienes) to give previously unknown thiophene-2-carboxylates and thiophene-2-carbonitriles, resp., both bearing pyrrole substituents. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8HPLC of Formula: 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.HPLC of Formula: 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ag(I)-Catalyzed rapid access to 2-amino-4-methylenethiazolines with potential applications in bioconjugation chemistry was written by Xiang, Lingling;Wu, Haiting;Liang, Yunshi;Deng, Huiying;He, Yiting;Xu, Qin;Zhang, Jing. And the article was included in Organic & Biomolecular Chemistry in 2021.COA of Formula: C4H7NS The following contents are mentioned in the article:

An Ag(I)-catalyzed tandem addition-cyclization of isothiocyanate RNCS (R = Ph, cyclohexyl, i-Pr, etc.) and propargylamine was successfully applied to the synthesis of 2-amino-4-methylenethiazolines I. This route features an unprecedented fast reaction rate with full conversion reached within 10 min at room temperature for aromatic isothiocyanates and excellent chemoselectivity for exocyclic products. The application of this strategy is further highlighted by the accelerated bioconjugation of propargylamine with fluorescein isothiocyanate (FITC) under Ag(I)-catalysis. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8COA of Formula: C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.COA of Formula: C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ag(I)-Catalyzed rapid access to 2-amino-4-methylenethiazolines with potential applications in bioconjugation chemistry was written by Xiang, Lingling;Wu, Haiting;Liang, Yunshi;Deng, Huiying;He, Yiting;Xu, Qin;Zhang, Jing. And the article was included in Organic & Biomolecular Chemistry in 2021.Application of 2253-73-8 The following contents are mentioned in the article:

An Ag(I)-catalyzed tandem addition-cyclization of isothiocyanate RNCS (R = Ph, cyclohexyl, i-Pr, etc.) and propargylamine was successfully applied to the synthesis of 2-amino-4-methylenethiazolines I. This route features an unprecedented fast reaction rate with full conversion reached within 10 min at room temperature for aromatic isothiocyanates and excellent chemoselectivity for exocyclic products. The application of this strategy is further highlighted by the accelerated bioconjugation of propargylamine with fluorescein isothiocyanate (FITC) under Ag(I)-catalysis. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Application of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A wide-angle antireflection surface for the visible spectrum was written by Paivanranta, B.;Saastamoinen, T.;Kuittinen, M.. And the article was included in Nanotechnology in 2009.Category: esters-buliding-blocks The following contents are mentioned in the article:

A surface consisting of periodically arranged nanopyramids producing wide-angle broad-band antireflection properties is presented. The reflectance of silicon dioxide is reduced below 0.45% over the visible spectral range (380-760 nm) for viewing angles from 0° to 40°. The surface is designed by using rigorous diffraction theory and fabricated first in silicon by exploiting its strong crystalline orientation and by using the wet etching process. The structure is transferred from silicon to transparent silicon dioxide by using nano-imprint lithog. and proportional reactive ion etching. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Category: esters-buliding-blocks).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Detection of volatile compounds of supple and mellow flavor type in Yanghe’s Lansejidian liquors by liquid-liquid extraction coupled with fractionation was written by Fan, Wenlai;Xu, Yan;Yang, Tingdong;Zhang, Yubai;Zhu, Guangsheng;Zhou, Xinhu;Chen, Xiang. And the article was included in Niangjiu in 2012.Category: esters-buliding-blocks The following contents are mentioned in the article:

The volatile compounds of supple and mellow flavor type in Yanghe’s Lansejidian liquor were isolated and separated by liquid-liquid extraction (LLE) and fractionation. The total of 933 peak were detected, and 672 compounds were identified by gas chromatog.-mass spectrometry (GC-MS). Of these, 261 volatiles were unknown. These compounds were alcs., aldehydes, ketones, fatty acids, esters, aromatic compounds, phenols, sulfur-containing compounds, furans, epoxy compounds, acetals, pyrroles, pyridines, lactones, and terpenes. Lactones and terpenes were first detected in Chinese liquors. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Category: esters-buliding-blocks).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Novel tricyclic poly (ADP-ribose) polymerase-1/2 inhibitors with potent anticancer chemopotentiating activity: Design, synthesis and biological evaluation was written by Li, Hui;Hu, Yan;Wang, Xueyan;He, Guangwei;Xu, Yungen;Zhu, Qihua. And the article was included in Bioorganic & Medicinal Chemistry in 2016.Electric Literature of C7H6N2O5 The following contents are mentioned in the article:

8,9-Dihydro-2,4,7,9a-tetraazabenzo[cd]azulen-6(7H)-ones were designed and synthesized as a new class of PARP-1/2 inhibitors. The compounds displayed a variable pattern of PARP-1/2 enzymes inhibition profile that, in part, paralleled the antiproliferative activity in cell lines. Among them, compound 9e exhibited not only the significant IC₅₀ value of 28 nM in the PARP-1 and 7.7 nM in PARP-2 enzyme assay, but also a profound synergic efficacy combined with temozolomide with PF₅₀ values of 2.6, 2.5, and 6.5 against MDA-MB-468, SW-620 and A549 and cell line, resp. This study involved multiple reactions and reactants, such as Methyl 4-hydroxy-5-nitronicotinate (cas: 1214387-19-5Electric Literature of C7H6N2O5).

Methyl 4-hydroxy-5-nitronicotinate (cas: 1214387-19-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Electric Literature of C7H6N2O5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

(Propargylsulfanyl)-2-aza-1,3,5-trienes as a direct source for novel family of highly functionalized 4,5-dihydro-1,3-thiazoles was written by Nedolya, Nina A.;Tarasova, Ol’ga A.;Albanov, Alexander I.;Klyba, Lyudmila V.;Trofimov, Boris A.. And the article was included in Tetrahedron in 2017.Related Products of 2253-73-8 The following contents are mentioned in the article:

A novel, simple approach to 2-(1-alkoxyprop-1-enyl)-5-ethenylidene-4,5-dihydro-1,3-thiazoles was disclosed through the reaction of (propargylthio)-2-aza-1,3,5-trienes (readily available from alkoxyallenes, isothiocyanates, and propargyl bromide) with potassium or sodium tert-butoxide (1.1-1.4 equiv) under mild conditions [DMSO/THF (∼1:4-5), ∼-30°, 15-30 min]. The process proceeds through deprotonation of an activated SCH₂ group, followed by intramol. [1,5]-ring-closure. Unlike alkyl-, benzyl-, and allylthio-analogs, the exclusive or competitive formation of seven-membered azaheterocycles was not observed This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Related Products of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Related Products of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of fused 3-amino-1,2,4-triazoles via sequential addition of aryl hydrazines to isothiocyanates and I₂-mediated cyclodesulfurization was written by Jiao, Shufeng;Wang, Zhen;Zhao, Qiongli;Yu, Wenquan;Chang, Junbiao. And the article was included in Tetrahedron in 2018.Name: Isopropylisothiocyanate The following contents are mentioned in the article:

A variety of fused 3-amino-1,2,4-triazole derivatives I (X= CH, N; R¹ = 7-Me, 5-Me, 8-Cl, etc.; R² = Ph, 4-MeC₆H₄, 4-FC₆H₄, 2-MeC₆H₄, etc.) were synthesized via addition of aryl hydrazines to isothiocyanates followed by I₂-mediated oxidative cyclodesulfurization. This transition-metal-free synthetic process provides facile access to 1,2,4-triazolo[4,3-a]pyridines and related heterocyclic frameworks bearing a 3-amino substituent from readily accessible substrates in an efficient and scalable fashion. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Name: Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Computation of Upper Flash Point of Chemical Compounds Using a Chemical Structure-Based Model was written by Gharagheizi, Farhad;Ilani-Kashkouli, Poorandokht;Mirkhani, Seyyed Alireza;Mohammadi, Amir H.. And the article was included in Industrial & Engineering Chemistry Research in 2012.Name: Ethyl 3-ethoxypropanoate The following contents are mentioned in the article:

A quant. structure-property relationship is presented to estimate the upper flash point of pure compounds using a multi-linear equation model with 8 parameters. All parameters are solely computed based on chem. structure. To develop this model, >3000 parameters were evaluated using the genetic algorithm multi-variate linear regression method to select the most statistically effective ones. Maximum average absolute relative deviation (mARD), ARD, squared correlation coefficient, and root mean squares of error from database (DIPPR 801) values for 1294 pure compounds were 25.76%, 3.56%, 0.95, and 17.42 K, resp. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Name: Ethyl 3-ethoxypropanoate).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: Ethyl 3-ethoxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Enantioselective, Catalytic One-Pot Synthesis of γ-Butyrolactone-Based Fragrances was written by Kumru, Ceyda;Classen, Thomas;Pietruszka, Joerg. And the article was included in ChemCatChem in 2018.Recommanded Product: 106-73-0 The following contents are mentioned in the article:

Herein the preparative (1 g scale), stereoselective syntheses of various alkyl-substituted γ-butyrolactone fragrances is described. The α,β-unsaturated γ-keto esters as starting materials were synthesized by a Horner-Wadsworth-Emmons reaction and are further reduced by an ene reductase and alc. dehydrogenase in a one-pot enzyme cascade to nine desired γ-butyrolactones, among them whisky and cognac lactone. The products were obtained in moderate to good yields and very good diastereoselectivities. Furthermore, the position of a ⁿBu-substituent was permutated to study the effect on the enzyme cascade. This study involved multiple reactions and reactants, such as Methyl heptanoate (cas: 106-73-0Recommanded Product: 106-73-0).

Methyl heptanoate (cas: 106-73-0) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 106-73-0

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics