Tag: 100-200

AgBF₄-catalyzed deoxygenative C2-amination of quinoline N-oxides with isothiocyanates was written by Xie, Long-Yong;Peng, Sha;Jiang, Li-Lin;Peng, Xia;Xia, Wen;Yu, Xianyong;Wang, Xing-Xing;Cao, Zhong;He, Wei-Min. And the article was included in Organic Chemistry Frontiers in 2019.Reference of 2253-73-8 The following contents are mentioned in the article:

A general, effective and convenient protocol for the direct synthesis of various 2-aminoquinolines I [R¹ = H, 3-Me, 6-CH=CHPh, etc.; R² = H, n-Bu, 2-pyridyl, etc.] through AgBF₄-catalyzed amination of quinoline N-oxides with isothiocyanates under base-, oxidant-free and mild conditions was developed. A sequential one-pot amination/cyclization could be performed to convert the quinoline-N-oxide into benzo[4,5]imidazo[1,2-a]quinoline without isolating any reaction intermediates. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Reference of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

AgBF₄-catalyzed deoxygenative C2-amination of quinoline N-oxides with isothiocyanates was written by Xie, Long-Yong;Peng, Sha;Jiang, Li-Lin;Peng, Xia;Xia, Wen;Yu, Xianyong;Wang, Xing-Xing;Cao, Zhong;He, Wei-Min. And the article was included in Organic Chemistry Frontiers in 2019.Safety of Isopropylisothiocyanate The following contents are mentioned in the article:

A general, effective and convenient protocol for the direct synthesis of various 2-aminoquinolines I [R¹ = H, 3-Me, 6-CH=CHPh, etc.; R² = H, n-Bu, 2-pyridyl, etc.] through AgBF₄-catalyzed amination of quinoline N-oxides with isothiocyanates under base-, oxidant-free and mild conditions was developed. A sequential one-pot amination/cyclization could be performed to convert the quinoline-N-oxide into benzo[4,5]imidazo[1,2-a]quinoline without isolating any reaction intermediates. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Safety of Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Safety of Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chemoselective Ullmann Reaction of α-Trisubstituted Thioamides: Synthesis of Novel 2-Iminobenzothiolanes was written by Bhattacharya, Anwesha;Thirupathi, Annaram;Natarajan, Pradeep;Peruncheralathan, Saravanan. And the article was included in ACS Omega in 2021.Related Products of 2253-73-8 The following contents are mentioned in the article:

New classes of unexplored benzo[b]thiolanes I [R = H, 6-F, 6-Cl, etc.; R¹ = Me, Et, Bn, etc.; R² = Et, Ph, Bn, etc.] were synthesized from trisubstituted thioamides through copper-catalyzed intramol. S-arylation of thioamides for the first time. This method provided good to excellent yields with fully controlled chemoselectivity. Unusually, iminobenzo[b]thiolanes were very stable under mild acidic conditions. A plausible mechanism was proposed for the chemoselective S-arylation process. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Related Products of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chemoselective Ullmann Reaction of α-Trisubstituted Thioamides: Synthesis of Novel 2-Iminobenzothiolanes was written by Bhattacharya, Anwesha;Thirupathi, Annaram;Natarajan, Pradeep;Peruncheralathan, Saravanan. And the article was included in ACS Omega in 2021.Reference of 2253-73-8 The following contents are mentioned in the article:

New classes of unexplored benzo[b]thiolanes I [R = H, 6-F, 6-Cl, etc.; R¹ = Me, Et, Bn, etc.; R² = Et, Ph, Bn, etc.] were synthesized from trisubstituted thioamides through copper-catalyzed intramol. S-arylation of thioamides for the first time. This method provided good to excellent yields with fully controlled chemoselectivity. Unusually, iminobenzo[b]thiolanes were very stable under mild acidic conditions. A plausible mechanism was proposed for the chemoselective S-arylation process. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Reference of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Reference of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

One-Pot Synthesis and Intramolecular Cyclization of 5-(Prop-2-ynylsulfanyl)-1H-pyrrol-2-amines: A Simple Approach to 2,7-Dihydrothiopyrano[2,3-b]pyrrol-6-amines was written by Nedolya, Nina A.;Tarasova, Olga A.;Albanov, Alexander I.;Trofimov, Boris A.. And the article was included in Synthesis in 2016.Formula: C4H7NS The following contents are mentioned in the article:

An expedient approach for the preparation of previously unknown 2,7-dihydrothiopyrano[2,3-b]pyrrol-6-amines I (R = Me, Et, Pr; RR = (CH₂)₄; R¹ = Me, Et, i-Pr, n-Bu, etc.) from readily accessible starting materials (propargylamines, isothiocyanates, and propargyl bromide) has been developed. The methodol. is based on the one-pot synthesis and thermally-induced fast rearrangement of 5-(prop-2-ynylsulfanyl)-1H-pyrrol-2-amines into 2,7-dihydrothiopyrano[2,3-b]pyrrol-6-amines. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Formula: C4H7NS).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Formula: C4H7NS

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

5-((3-bromoallyl)sulfonyl)-1H-tetrazoles for bromodiene synthesis was written by Suzuki, Takuro;Fukagawa, Seiya;Yoshino, Tatsuhiko;Anada, Masahiro;Matsunaga, Shigeki. And the article was included in Heterocycles in 2018.Application of 2253-73-8 The following contents are mentioned in the article:

Reagents I (R = Me, Ph, 1-adamantyl, etc.) for one-step construction of conjugated bromodienes (1E,3E)/(1E,3Z)-BrCH=CHCH=CHR¹ (R¹ = t-Bu, 4-chlorphenyl, cyclohexyl, etc.) from aldehydes R¹CHO are described. Various 1-alkyl- and 1-aryl-tetrazolyl bromoallylic sulfones I were synthesized and evaluated in bromodiene synthesis. 1-alkyl-tetrazolyl sulfones selectively afforded (1E,3Z)-bromodienes, while 1-aryl-tetrazolyl sulfones resulted in low selectivity. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Application of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comparative study of volatile compounds in the fresh fruits of Mandragora autumnalis was written by Hanus, L. O.;Dembitsky, V. M.;Moussaieff, A.. And the article was included in Acta Chromatographica in 2006.Name: Ethyl 3-ethoxypropanoate The following contents are mentioned in the article:

Extracts of Mandragora autumnalis (mandrake) fruit have been analyzed by GC-MS. One-hundred and thirty-five compounds were identified in extracts obtained from the fruit after removal of the seeds – twenty-three n-alkanes, one branched-chain alkane, two cyclohexanes, eight alkenes, two branched-chain alkenes, three alcs., three aldehydes, six ketones, eight heterocyclic compounds, four thio compounds, six benzene hydrocarbons, three phenols, eighteen carboxylic acids, and forty-eight esters of carboxylic acids. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Name: Ethyl 3-ethoxypropanoate).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Name: Ethyl 3-ethoxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent in Vitro and in Vivo Anticancer Activities was written by Medellin, Derek C.;Zhou, Qiong;Scott, Robert;Hill, R. Matthew;Frail, Sarah K.;Dasari, Ramesh;Ontiveros, Steven J.;Pelly, Stephen C.;van Otterlo, Willem A. L.;Betancourt, Tania;Shuster, Charles B.;Hamel, Ernest;Bai, Ruoli;LaBarbera, Daniel V.;Rogelj, Snezna;Frolova, Liliya V.;Kornienko, Alexander. And the article was included in Journal of Medicinal Chemistry in 2016.Product Details of 763-69-9 The following contents are mentioned in the article:

Docking studies of tubulin-targeting C2-substituted 7-deazahypoxanthine analogs of marine alkaloid rigidins led to the design and synthesis of compounds containing linear C2-substituents. The C2-alkynyl analog I was found to have double- to single-digit nanomolar antiproliferative IC₅₀ values and showed statistically significant tumor size reduction in a colon cancer mouse model at nontoxic concentrations These results provide impetus and further guidance for the development of these rigidin analogs as anticancer agents. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Product Details of 763-69-9).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Product Details of 763-69-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Design, synthesis and fungicidal bioactivity of 1,2,4-triazoles or thiadiazoles containing a benzenesulfonamide moiety was written by Chen, Minggui;Hua, Xuewen;Wei, Wei;Zhang, Dongkai;Liu, Ming;Wu, Changchun;Zhou, Sha;Li, Yuxin;Wang, Baolei;Zhou, Sha;Li, Zhengming. And the article was included in Yingyong Huaxue in 2017.Related Products of 2253-73-8 The following contents are mentioned in the article:

In order to explore efficient, low toxic and eco-friendly fungicides, a series of 1,2,4-triazole and thiadiazole derivatives containing benzenesulfonamide moieties was designed and synthesized. Their chem. structures were confirmed by NMR spectroscopy (NMR), mass spectrometry and elemental anal. Preliminary fungicidal bioassay in vitro was carried out against seven plant pathogenic fungi and the results showed that the prepared compounds exhibited moderate fungicidal activities against Fusarium moniliforme in comparison with com. Azoxystrobin. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Related Products of 2253-73-8).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Related Products of 2253-73-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

I₂-Catalyzed Oxidative N-S Bond Formation: Metal-Free Regiospecific Synthesis of N-Fused and 3,4-Disubstituted 5-Imino-1,2,4-thiadiazoles was written by Tumula, Nagaraju;Jatangi, Nagesh;Palakodety, Radha Krishna;Balasubramanian, Sridhar;Nakka, Mangarao. And the article was included in Journal of Organic Chemistry in 2017.Application In Synthesis of Isopropylisothiocyanate The following contents are mentioned in the article:

A novel and expeditious approach for the synthesis of N-fused and 3,4-disubstituted 5-imino-1,2,4-thiadiazole derivatives has been achieved through the mol. iodine-catalyzed oxidative cyclization of 2-aminopyridine/amidine and isothiocyanate via N-S bond formation at ambient temperature The present one-pot transition-metal-free protocol provides the facile and highly efficient regiospecific synthesis of various 1,2,4-thiadiazole derivatives in a scaled-up manner with good to excellent yields using inexpensive I₂ as a catalyst. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Application In Synthesis of Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics