Tag: 100-200

Aromatic and sensory characterization of Maturana Blanca wines made with different technologies was written by Naranjo, Ana;Martinez-Lapuente, Leticia;Ayestaran, Belen;Guadalupe, Zenaida;Perez, Irene;Canals, Clara;Adell, Elena. And the article was included in Beverages in 2021.Reference of 706-14-9 This article mentions the following:

Vitis vinifera L. cv. Maturana Blanca is an autochthonous minor variety recently recovered in the Rioja Qualified Denomination of Origin (D.O.Ca Rioja, Spain) for the production of monovarietal white wines with singular and differentiated characteristics. In this paper, Maturana Blanca wines made with different technologies were analyzed by sensory anal. and aromatic profile by gas chromatog.-mass detector. Maturana Blanca wines were characterized by low pH, high acidity, and yellowish tonalities. The compounds that most influenced the aroma of Maturana Blanca wines were those related to fruity (acetates and Et esters), floral aromas (2-phenylethanol), and spicy notes (γ-decalactone). These wines were mainly characterized by volatile compounds of fruity aromas of banana and apple. The use of pre-fermentative maceration increased the concentration of Et esters and acetates and produced wines with higher odor activity values, indicating a greater aromatic intensity. The aromatic profile of Maturana Blanca wines fermented in oak barrels showed a greater complexity as they were also characterized by the presence of important amounts of furfural, whiskey lactone, and eugenol. The sensory anal. confirmed the results obtained in the aromatic anal., and described the wines as fresh and balanced in mouth, with notes of acidity and medium to high persistence. These results will contribute to a better knowledge of this white variety. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Reference of 706-14-9).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Reference of 706-14-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bifunctional acyclic nucleoside phosphonates: 2. Symmetrical 2-{[bis(phosphono)methoxy]methyl}ethyl derivatives of purines and pyrimidines was written by Vrbkova, Silvie;Dracinsky, Martin;Holy, Antonin. And the article was included in Collection of Czechoslovak Chemical Communications in 2007.Electric Literature of C9H16O4 This article mentions the following:

Novel bisphosphonate alkylating agent, tetraisopropyl {2-[(mesyloxy)methyl]propane-1,3-diyl}bis(oxymethylene)bisphosphonate (I), was synthesized from di-Et 2,2-bis-(hydroxymethyl)malonate. Decarbethoxylation of the di-Et 2,2-dimethyl-1,3-dioxane-5,5-dicarboxylate was followed by chloromethylation of 2-[(benzyloxy)methyl]propane-1,3-diol and Arbuzov reaction with triisopropyl phosphite. Bisphosphonate building block I was used in the alkylation of various nucleobases (2-amino-6-chloropurine, adenine, 2-amino-6-(cyclopropyl)aminopurine, cytosine, uracil and 4-methoxy-5-methylpyrimidin-2(1H)-one). N⁹-Substituted purines and N¹-substituted pyrimidines were converted to appropriate free bisphosphonic acids. No antiviral or cytostatic activity was detected. In the experiment, the researchers used many compounds, for example, Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate (cas: 82962-54-7Electric Literature of C9H16O4).

Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate (cas: 82962-54-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Electric Literature of C9H16O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Production of volatile compounds by wild-type yeasts in a natural olive-derived culture medium was written by Montano, Alfredo;Cortes-Delgado, Amparo;Sanchez, Antonio Higinio;Ruiz-Barba, Jose Luis. And the article was included in Food Microbiology in 2021.COA of Formula: C6H12O2 This article mentions the following:

The production of volatile compounds in naturally fermented green table olives from Manzanilla cultivar was investigated. A total of 62 volatile compounds were detected after 24 wk of fermentation To clarify the contribution of yeasts to the formation of these compounds, such microorganisms were isolated from the corresponding fermenting brines. Five major yeast strains were identified: Nakazawaea molendinolei NC168.1, Zygotorulaspora mrakii NC168.2, Pichia manshurica NC168.3, Candida adriatica NC168.4, and Candida boidinii NC168.5. When these yeasts were grown as pure cultures in an olive-derived culture medium, for 7 days at 25°C, the number of volatiles produced ranged from 22 (P. manshurica NC168.3) to 60 (C. adriatica NC168.4). Contribution of each yeast strain to the qual. volatile profile of fermenting brines ranged from 19% (P. manshurica NC168.3) to 48% (Z. mrakii NC168.2 and C. adriatica NC168.4). It was concluded that C. adriatica NC168.4 presented the best aromatic profile, being a solid candidate to be part of a novel starter culture to enhance the organoleptic properties of naturally fermented green table olives. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5COA of Formula: C6H12O2).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. COA of Formula: C6H12O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rapid Assembly of Saturated Nitrogen Heterocycles in One-Pot: Diazo-Heterocycle “Stitching” by N-H Insertion and Cyclization was written by Boddy, Alexander J.;Affron, Dominic P.;Cordier, Christopher J.;Rivers, Emma L.;Spivey, Alan C.;Bull, James A.. And the article was included in Angewandte Chemie, International Edition in 2019.Synthetic Route of C10H11FO2 This article mentions the following:

Methods that provide rapid access to new heterocyclic structures in biol. relevant chem. space provide important opportunities in drug discovery. Here, a strategy is described for the preparation of 2,2-disubstituted azetidines, pyrrolidines, piperidines, and azepanes bearing ester and diverse aryl substituents. A one-pot rhodium catalyzed N-H insertion and cyclization sequence uses diazo compounds to stitch together linear 1,m-haloamines (m = 2-5) to rapidly assemble 4-, 5-, 6-, and 7-membered saturated nitrogen heterocycles in excellent yields. Over fifty examples are demonstrated, including examples with diazo compounds derived from biol. active compounds The products can be functionalized to afford α,α-disubstituted amino acids and applied to fragment synthesis. In the experiment, the researchers used many compounds, for example, Ethyl 2-fluorophenylacetate (cas: 584-74-7Synthetic Route of C10H11FO2).

Ethyl 2-fluorophenylacetate (cas: 584-74-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Synthetic Route of C10H11FO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The nature of field effects and their fall-off with distance: the acidity of substituted quinuclidinium and bicyclooctylammonium ions was written by Adcock, W.;Anvia, F.;Butt, G.;Cook, A.;Duggan, P.;Grob, C. A.;Marriott, S.;Rowe, J.;Taagepera, M.. And the article was included in Journal of Physical Organic Chemistry in 1991.Application In Synthesis of Methyl 4-aminobicyclo[2.2.2]octane-1-carboxylate This article mentions the following:

Gas-phase acidities are reported for a series of substituted quinuclidinium and bicyclo[2.2.2]octylammonium ions. Ab initio calculation are also reported for these equilibrium at the STO-3G and 3-21G (for the quinuclidines) bases and can be used to extend the results. PK_a values obtained for the bicyclooctylammonium ions are compared with previously reported results for the quinuclidinium ions. The results, as a whole, are considered together with similar values obtained for other saturated systems, to look at the varying transmission of field effects with distance. The fall-off observed between the two series in the gas phase is considerably less than expected from simple electrostatics. In contradiction with a recent claim, it is also shown that field effects, as measured by the parameter σ_F, give a good measure of the effect of the substituents in each series compared with a combination of resonance and electronegativity effects. In the experiment, the researchers used many compounds, for example, Methyl 4-aminobicyclo[2.2.2]octane-1-carboxylate (cas: 135908-33-7Application In Synthesis of Methyl 4-aminobicyclo[2.2.2]octane-1-carboxylate).

Methyl 4-aminobicyclo[2.2.2]octane-1-carboxylate (cas: 135908-33-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application In Synthesis of Methyl 4-aminobicyclo[2.2.2]octane-1-carboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The effect of an alkoxy group on the kinetic and thermodynamic acidity of benzene and toluene was written by Schlosser, Manfred;Maccaroni, Paola;Marzi, Elena. And the article was included in Tetrahedron in 1998.Product Details of 81245-24-1 This article mentions the following:

2-, 3- And 4-Methoxytoluene can be selectively metalated at an O-adjacent ortho position when butylithium or tert-butyllithium in the presence of sodium (potassium) tert-butoxide or N,N,N’,N”,N”-pentamethyldiethylenetriamine are employed as reagents. In contrast, lithium diisopropylamide or lithium 2,2,6,6-tetramethylpiperidide deprotonate the benzylic α-position of 2- and 3-methoxytoluene exclusively and of 4-methoxytoluene preferentially. These relative reactivities can be rationalized by an interplay of transition state stabilizing and destabilizing forces (dipole matching and metal coordination vs. lone pair repulsion). In the experiment, the researchers used many compounds, for example, Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1Product Details of 81245-24-1).

Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Product Details of 81245-24-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comparative investigation on aroma profiles of five different mint (Mentha) species using a combined sensory, spectroscopic and chemometric study was written by Zhang, Jiguang;Li, Man;Zhang, Hongfei;Pang, Xueli. And the article was included in Food Chemistry in 2022.Synthetic Route of C6H12O2 This article mentions the following:

Mint is a widely used aromatic plant, and the aroma varies among different species. The aroma of five mint species, Mentha citrata L. (MC), Mentha piperita L. (MPI), Mentha spicata L. (MSP), Mentha persicaria L. (MPE), and Mentha suaveolens L. (MSU), were comparatively studied on the sensorial and mol. level. Quant. descriptive anal. revealed that MC presented a pronounced lemon-like note, MSU is dominated by citrus and floral aromas, MPI has a prominent minty flavor, MSP and MPE have a similar scent, both of which are flavored with a spearmint-like note. Forty-one odorants with odor activity values (OAVs) ≥1 were characterized. Principal component anal. and orthogonal partial least squares discrimination anal. based on OAVs indicated that α-citral, menthofuran, isomenthone, menthol, carvone, and linalool were potential odor-active markers for five mint species discrimination. This study herein will provide guidance for mint resources utilization and also aid mint breeding with better flavor. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5Synthetic Route of C6H12O2).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Synthetic Route of C6H12O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Flavor components in tobacco capsules identified through non-targeted quantitative analysis was written by Lim, Hyun-Hee;Choi, Kyeong-Yun;Shin, Ho-Sang. And the article was included in Journal of Mass Spectrometry in 2022.Related Products of 706-14-9 This article mentions the following:

Tobacco flavors increase the attractiveness of a tobacco brand and ultimately promote addiction. Information about what flavor and how much flavor is in flavor capsules can provide an effective way to regulate tobacco flavor. In this study, 128 flavor chems. were identified and quantified by gas chromatog.-mass spectrometry using libraries and authentic standards Validation of the developed method was performed for interference, detection limits, calibration curves, accuracy, and precision. Menthol was the main ingredient in all capsules, and the carcinogenic pulegone was detected. Detected menthofuran, benzyl alc., geraniol, and eugenol cause toxic or severe irritation, and detected lactones can increase nicotine addiction by inhibiting nicotine metabolism in smokers. Margin of exposures for carcinogenic pulegone and non-carcinogenic menthol were well below safety thresholds, indicating a significant risk of inhalation exposure. It is desirable to prohibit the use of flavor capsules in consideration of human risk. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Related Products of 706-14-9).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Related Products of 706-14-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Analysis and reconstitution of characteristic aromas in Tie Guanyin tea based on sensory-oriented separation and its application in cigarette flavoring was written by Cao, Xiaoliang;Zhang, Feng;Chai, Guobi;Liu, Jiazeng;Hong, Zucan;Zhou, Peichen;Sun, Shihao;Hu, Jun;Mao, Zhongyi;Ji, Lingbo;Fu, Yingjie;Xi, Hui. And the article was included in Zhongguo Yancao Xuebao in 2021.Application In Synthesis of 5-Hexyldihydrofuran-2(3H)-one This article mentions the following:

[Objective] This study aims to establish a method of natural flavor aroma reconstruction and style enhancement and applied it to cigarette flavoring. [Methods] With Tie Guanyin tea extracts as the object, characteristic aroma groups of Tie Guanyin tea were collected by sensory-oriented gel chromatog. separation Qual. and quant. anal. was conducted by HS-SPME combined with GC/MS anal. The olfactory thresholds of the 41 aroma components in ethanol were determined by three-alternative forcedchoice method, and their odor activity values (OAVs) were calculated on the basis of their mass fraction. On this basis, their contributions to the aroma of tea were estimated Organoleptic evaluation of the key aroma components based on OAV was verified by recombining reconstitution of the key aroma components in tea extracts, comparative evaluation based on aroma profile method and enhancement of characteristic aromas. [Results] 1) 117 streams were collected by sensory-oriented Gel chromatog. separation, in which 28 characteristic aroma streams of Tie Guanyin tea were separated and enriched. 2) 41 characteristic aroma components in Tie Guanyin tea extract were identified by screening, among which 22 aroma components, such as linalool, nerolidol, phenethyl alc., geraniol, citral, indole, Me jasmonate, and Et caproate, contribute the most to the sensory effects. 3) The aroma profile of the recombinant of key aroma components was basically consistent with that of Tie Guanyin tea extracts, so it could reproduce the aroma characteristics style of tea better. 4) The combination of tea aroma recombinants and tea extracts could enhance the tea flavor in cigarettes, enhance the floral scent, delicate fragrance, fruity fragrance significantly, increase the aroma intensity significantly and improve the smoking quality of cigarettes. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Application In Synthesis of 5-Hexyldihydrofuran-2(3H)-one).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application In Synthesis of 5-Hexyldihydrofuran-2(3H)-one

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hit to Lead Account of the Discovery of Bisbenzamide and Related Ureidobenzamide Inhibitors of Rho Kinase was written by Morwick, Tina;Buttner, Frank H.;Cywin, Charles L.;Dahmann, Georg;Hickey, Eugene;Jakes, Scott;Kaplita, Paul;Kashem, Mohammed A.;Kerr, Steven;Kugler, Stanley;Mao, Wang;Marshall, Daniel;Paw, Zofia;Shih, Cheng-Kon;Wu, Frank;Young, Erick. And the article was included in Journal of Medicinal Chemistry in 2010.Category: esters-buliding-blocks This article mentions the following:

A highly selective series of bisbenzamide inhibitors of Rho-associated coiled-coil forming protein kinase (ROCK) and a related ureidobenzamide series, both identified by high throughput screening (HTS), are described. Details of the hit validation and lead generation process, including structure-activity relationship (SAR) studies, a selectivity assessment, target-independent profiling (TIP) results, and an anal. of functional activity using a rat aortic ring assay are discussed. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Category: esters-buliding-blocks).

3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics