Tag: 0-100

Synthetic Route of C5H6O2In 2021 ,《Synthesis and Toxicity Evaluation of New Pyrroles Obtained by the Reaction of Activated Alkynes with 1-Methyl-3-(cyanomethyl)benzimidazolium Bromide》 appeared in Molecules. The author of the article were Ivan, Beatrice-Cristina; Dumitrascu, Florea; Anghel, Adriana Iuliana; Ancuceanu, Robert Viorel; Shova, Sergiu; Dumitrescu, Denisa; Draghici, Constantin; Olaru, Octavian Tudorel; Nitulescu, George Mihai; Dinu, Mihaela; Barbuceanu, Stefania-Felicia. The article conveys some information:

A series of new pyrrole derivatives I (R = H, methoxycarbonyl, ethoxycarbonyl; R1 = Bz, methoxycarbonyl, ethoxycarbonyl, (propan-2-yloxy)carbonyl) were designed as chem. analogs of the 1,4-dihydropyridines drugs in order to develop future new calcium channel blockers. The new tri- and tetra-substituted N-arylpyrroles I were synthesized by the one-pot reaction of 1-methyl-3-cyanomethyl benzimidazolium bromide with substituted alkynes RCCR1 having at least one electron-withdrawing substituent, in 1,2-epoxybutane, acting both as the solvent and reagent to generate the corresponding benzimidazolium N3-ylide. The structural characterization of the new substituted pyrroles I was based on IR, NMR spectroscopy as well as on single crystal X-ray anal. The toxicity of the new compounds was assessed on the plant cell using Triticum aestivum L. species and on the animal cell using Artemia franciscana Kellogg and Daphnia magna Straus crustaceans. The compounds showed minimal phytotoxicity on Triticum rootlets and virtually no acute toxicity on Artemia nauplii, while on Daphnia magna, it induced moderate to high toxicity, similar to nifedipine. This research indicates that the newly synthesized pyrrole derivatives are promising mols. with biol. activity and low acute toxicity. The experimental part of the paper was very detailed, including the reaction process of Ethyl propiolate(cas: 623-47-2Synthetic Route of C5H6O2)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Synthetic Route of C5H6O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Langdon, Jayse; Cui, Zehao; Manthiram, Arumugam published an article in 2021. The article was titled 《Role of Electrolyte in Overcoming the Challenges of LiNiO2 Cathode in Lithium Batteries》, and you may find the article in ACS Energy Letters.Product Details of 872-36-6 The information in the text is summarized as follows:

LiNiO2 (LNO) is a high-capacity and model cathode first discovered in the 1980s that fell out of favor due to its intrinsic instabilities. However, research activities toward LNO are once again on the rise as the push for higher-energy-d. cells marches on. We demonstrate here that with appropriate modern electrolytes, major performance improvements can be achieved with LNO with no addnl. modifications. Cells with a localized high concentration electrolyte (LHCE) deliver 92% capacity retention after 200 cycles compared with 56% capacity retention in a baseline carbonate electrolyte, maintain 94% capacity after high-voltage storage compared with 77% capacity, and display a higher onset temperature of thermal runaway of 244°C compared with 188°C. These improvements are attributed to the LHCE’s high oxidative stability and its formation of fluorine-rich interphases. Although further characterization of this new class of electrolyte is necessary, this work demonstrates that modern electrolytes can be drop-in enablers of high-capacity, long-cycle-life cells. After reading the article, we found that the author used Vinylene carbonate(cas: 872-36-6Product Details of 872-36-6)

Vinylene carbonate(cas: 872-36-6) belongs to esters. Alkyl carbonates find applications as solvents for lithium ion battery electrolytes and the use of high quality battery grade electrolytes having extremely low water (<10 ppm) and acid (<10 ppm) contents are critical for achieving high electrochemical performance.Product Details of 872-36-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Reactions of alkyl 4-hydroxybut-2-ynoates with arenes under superelectrophilic activation with triflic acid or HUSY zeolite: Alternative propargylation or allenylation of arenes, and synthesis of furan-2-onesã€?were Devleshova, Natalia A.; Lozovskiy, Stanislav V.; Vasilyev, Aleksander V.. And the article was published in Tetrahedron in 2019. Safety of Ethyl propiolate The author mentioned the following in the article:

Reactions of alkyl 4-aryl(or 4,4-diaryl)-4-hydroxybut-2-ynoates [Ar(H or Ar’)(OH)C4-C3≡C2-CO2Alk], (Ar = Ar’ = Ph, 4-MeC6H4, 4-MeOC6H4, 4-BrC6H4, etc.; Alk = Me, Et) with arenes under the action of triflic acid TfOH or HUSY zeolite result in the formation of two main compounds, aryl substituted furan-2-ones I (Ar1 = Ar2 = Ph, 4-MeC6H4, 4-MeOC6H4, 4-BrC6H4, etc.; Ar3 = 2,5-di-MeC6H3, 3,4-di-MeC6H3, 3-F,4-MeC6H3, etc.) or products of propargylation II (Ar1 = Ph, 4-MeC6H4, 4-MeOC6H4, 4-BrC6H4, etc.; Ar3 = 2,5-di-MeC6H3, 3,4-di-MeC6H3, 3-F,4-MeC6H3, etc.; Alk = Me, Et) of electron rich arenes. Key reactive intermediates in these transformations are the corresponding O,O-diprotonated forms of starting butynoates, Ar(H or Ar’)(+OH2)C4-C3≡C2-C(=O+H)(OAlk), dehydration of which gives rise to mesomeric propargyl-allenyl cations Ar(H or Ar’)(OH)4C+-C3≡C2-C(=O+H)(OAlk) â†?Ar(H or Ar’)(OH)4C = C3 = 2C+-C(=O+H)(OAlk), having two electrophilic centers on the carbons C4 and C2 resp. Reactions of these species with arenes at C4 lead to products of arene propargylation, alternatively, reactions at C2 result in allenylation of arenes, followed by further transformation into furan-2-ones. Using quantum chem. calculations by the DFT method, it has been shown that the reactivity of such propargyl-allenyl cations is mainly explained by orbital factors. Plausible reaction mechanism is discussed.Ethyl propiolate(cas: 623-47-2Safety of Ethyl propiolate) was used in this study.

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Safety of Ethyl propiolate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Related Products of 623-47-2In 2020 ,《Regioselective Alkyne Cyclotrimerization with an In Situ-Generated [Fe(II)H(salen)]·Bpin Catalystã€?was published in ACS Catalysis. The article was written by Provis-Evans, Cei B.; Lau, Samantha; Krewald, Vera; Webster, Ruth L.. The article contains the following contents:

A mild, efficient, and regiospecific catalytic cyclotrimerization of alkynes to form 1,2,4-substituted arenes has been discovered. From a cheap and air-stable [Fe(salen)]2-μ-oxo complex and readily available pinacol borane (HBpin), a monomeric [FeH(salen)]·Bpin species formed in situ acts as the active catalyst. This species is shown to feature a hemilabile salen ligand stabilized via interactions with the boron entity. The formation, identity, and reaction mechanism of the active species are supported by complementary kinetic, spectroscopic, and computational data. The active catalyst undergoes hydrometallation of a coordinated alkyne to form a vinyl iron species, stepwise additions of two more alkynes across the Fe-C bond to form a pendant triene, which upon ring-closure forms the arene product. The catalytic cycle is closed by substitution of the product with the alkyne substrate. With the active [FeH(salen)]·Bpin catalyst, atom-efficient, intermol. trimerization is shown with high regioselectivity for a diverse range of substrate substitution patterns and presence of functional groups. In addition to this study using Ethyl propiolate, there are many other studies that have used Ethyl propiolate(cas: 623-47-2Related Products of 623-47-2) was used in this study.

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Related Products of 623-47-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Huang, Xin; Xu, Yingying; Li, Jianglian; Lai, Ruizhi; Luo, Yi; Wang, Qiantao; Yang, Zhongzhen; Wu, Yong published their research in Chinese Chemical Letters in 2021. The article was titled 《Synthesis of aminoisoquinolines via Rh-catalyzed [4 + 2] annulation of benzamidamides with vinylene carbonateã€?Application of 872-36-6 The article contains the following contents:

A new strategy is developed for the synthesis of 1-aminoisoquinolines I (R1 = H, 6-F, 7-Cl, 8-Me, etc.; R2 = t-Bu, n-Bu, Ph, PhCH2, etc.). This Rh(III)-catalyzed [4 + 2] annulation reaction employs benzamidines II as efficient directing groups and the vinylene carbonate as an acetylene surrogate. Addnl., the reaction features broad substrate scopes and good yields by only producing carbonate anion as byproduct. The experimental process involved the reaction of Vinylene carbonate(cas: 872-36-6Application of 872-36-6)

Vinylene carbonate(cas: 872-36-6) belongs to esters. Alkyl carbonates find applications as solvents for lithium ion battery electrolytes and the use of high quality battery grade electrolytes having extremely low water (<10 ppm) and acid (<10 ppm) contents are critical for achieving high electrochemical performance.Application of 872-36-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Metal-Free Synthesis of Pyrazoles and Chromenopyrazoles from Hydrazones and Acetylenic Estersã€?was published in ChemistrySelect in 2020. These research results belong to Bhaskaran, Rasmi P.; Janardhanan, Jith C.; Babu, Beneesh P.. Safety of Ethyl propiolate The article mentions the following:

An efficient, metal-free synthesis of pyrazoles and chromenopyrazoles from aldehyde hydrazones and acetylenic esters was developed. A library of mols. with diverse functional groups was synthesized using substituted hydrazones and alkynes, both sym. and unsym. ones. The derivatives were isolated in moderate to good yields. The experimental part of the paper was very detailed, including the reaction process of Ethyl propiolate(cas: 623-47-2Safety of Ethyl propiolate)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Safety of Ethyl propiolate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《High-throughput combinatorial screening of multi-component electrolyte additives to improve the performance of Li metal secondary batteriesã€?were Matsuda, Shoichi; Nishioka, Kiho; Nakanishi, Shuji. And the article was published in Scientific Reports in 2019. SDS of cas: 872-36-6 The author mentioned the following in the article:

Data-driven material discovery has recently become popular in the field of next-generation secondary batteries. However, it is important to obtain large, high quality data sets to apply data-driven methods such as evolutionary algorithms or Bayesian optimization. Combinatorial high-throughput techniques are an effective approach to obtaining large data sets together with reliable quality. In the present study, we developed a combinatorial high-throughput system (HTS) with a throughput of 400 samples/day. The aim was to identify suitable combinations of additives to improve the performance of lithium metal electrodes for use in lithium batteries. Based on the high-throughput screening of 2002 samples, a specific combination of five additives was selected that drastically improved the coulombic efficiency (CE) of a lithium metal electrode. Importantly, the CE was remarkably decreased merely by removing one of these components, highlighting the synergistic basis of this mixture The results of this study show that the HTS presented herein is a viable means of accelerating the discovery of ideal yet complex electrolytes with multiple components that are very difficult to identify via conventional bottom-up approach. In the part of experimental materials, we found many familiar compounds, such as Vinylene carbonate(cas: 872-36-6SDS of cas: 872-36-6)

Vinylene carbonate(cas: 872-36-6) belongs to esters. Alkyl carbonates find applications as solvents for lithium ion battery electrolytes and the use of high quality battery grade electrolytes having extremely low water (<10 ppm) and acid (<10 ppm) contents are critical for achieving high electrochemical performance.SDS of cas: 872-36-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《A dicopper(I)-dimesoionic carbene complex as a click catalyst: mechanistic implications》 was written by Beerhues, Julia; Fauche, Kevin; Cisnetti, Federico; Sarkar, Biprajit; Gautier, Arnaud. Recommanded Product: 623-47-2This research focused ontriazole copper mesoionic binuclear carboxylate bridged complex preparation; click reaction catalyst copper mesoionic binuclear ditriazolylmethane carboxylate complex; cycloaddition kinetics catalyst copper mesoionic carbene ditriazolylmethane carboxylate complex; crystal mol structure copper mesoionic carbene ditriazolylmethane carboxylate complex. The article conveys some information:

A dicopper(I) complex comprising a dimesoionic carbene, bis(triazolyl)methane, and an acetate-bridge is synthesized and fully characterized. This complex is a potent pre-catalyst for the azide-alkyne cycloaddition reaction. A full kinetic investigation shows a first order in azide and a catalyst order smaller than one due to an equilibrated dimerization of the catalyst. In addition to this study using Ethyl propiolate, there are many other studies that have used Ethyl propiolate(cas: 623-47-2Recommanded Product: 623-47-2) was used in this study.

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Recommanded Product: 623-47-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reference of Ethyl propiolateIn 2019 ,《Triple copper catalysis for the synthesis of vinyl triazoles》 appeared in Green Chemistry. The author of the article were Baldassari, Lucas L.; Cechinatto, Eduardo A.; Moro, Angelica V.. The article conveys some information:

Synthesis of vinyl 1,2,3-triazoles through a one-pot sequence, enabled by the same copper catalyst of three different reactions: hydroboration involving an alkyne, azidation for a vinyl boronate and azide-alkyne cycloaddition was reported. In the part of experimental materials, we found many familiar compounds, such as Ethyl propiolate(cas: 623-47-2Reference of Ethyl propiolate)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Reference of Ethyl propiolate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,Miele, Ermanno; Dose, Wesley M.; Manyakin, Ilya; Frosz, Michael H.; Ruff, Zachary; De Volder, Michael F. L.; Grey, Clare P.; Baumberg, Jeremy J.; Euser, Tijmen G. published an article in Nature Communications. The title of the article was 《Hollow-core optical fibre sensors for operando Raman spectroscopy investigation of Li-ion battery liquid electrolytes》.Computed Properties of C3H2O3 The author mentioned the following in the article:

Improved anal. tools are urgently required to identify degradation and failure mechanisms in Li-ion batteries. However, understanding and ultimately avoiding these detrimental mechanisms requires continuous tracking of complex electrochem. processes in different battery components. Here, we report an operando spectroscopy method that enables monitoring the chem. of a carbonate-based liquid electrolyte during electrochem. cycling in Li-ion batteries with a graphite anode and a LiNi0.8Mn0.1Co0.1O2 cathode. By embedding a hollow-core optical fiber probe inside a lab-scale pouch cell, we demonstrate the effective evolution of the liquid electrolyte species by background-free Raman spectroscopy. The anal. of the spectroscopy measurements reveals changes in the ratio of carbonate solvents and electrolyte additives as a function of the cell voltage and show the potential to track the lithium-ion solvation dynamics. The proposed operando methodol. contributes to understanding better the current Li-ion battery limitations and paves the way for studies of the degradation mechanisms in different electrochem. energy storage systems. The experimental process involved the reaction of Vinylene carbonate(cas: 872-36-6Computed Properties of C3H2O3)

Vinylene carbonate(cas: 872-36-6) belongs to esters. Alkyl carbonates find applications as solvents for lithium ion battery electrolytes and the use of high quality battery grade electrolytes having extremely low water (<10 ppm) and acid (<10 ppm) contents are critical for achieving high electrochemical performance.Computed Properties of C3H2O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics