Esters-buliding-blocks

Synthesis of Nα-protected amino acid/peptide Weinreb amides employing N,N’-carbonyldiimidazole as activating agent; studies on docking and antibacterial activities was written by Uma, K.;Lalithamba, H. S.;Raghavendra, M.;Chandramohan, Vivek;Anupama, C.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2016.Computed Properties of C16H24N2O4 This article mentions the following:

An efficient method for the synthesis of Nα-protected amino/peptide Weinreb amides (N-methoxy-N-methylamides) employing N,N’-carbonyldiimidazole (CDI) has been achieved. Nα-protected amino/peptide acids were treated with N,N’-carbonyldiimidazole, followed by the addition of N,O-dimethylhydroxylamine hydrochloride salt to yield the desired compounds The synthesized compounds were mainly gums, a few were solids, after the simple workup, and were characterized by IR, ¹H NMR, ¹³C NMR and HRMS. The Weinreb amides were subjected to in silico studies, to predict the preferred orientation and binding affinity between the mols. using scoring functions. The ligand N-Fmoc-L-Phe-N(OCH₃)CH₃ showed min. binding energy – 29.85 kcal/mol with Escherichia coli and the ligand N-Fmoc-L-Ala-N(OCH₃)CH₃ showed min. binding energy -24.79 kcal/mol with Pseudomonas aeruginosa, -25.01 kcal/mol with Staphylococcus aureus. Based on the min. binding energies, antibacterial activities have been conducted for a few of the synthesized compounds In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Computed Properties of C16H24N2O4).

(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C16H24N2O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Artemisia magellanica. Chemical composition of the essential oil from an unexplored endemic species of Patagonia was written by Gonzalez, Silvia B.;Gastaldi, Bruno;Catalan, Cesar;Di Leo Lira, Paola;Retta, Daiana;van Baren, Catalina M.;Bandoni, Arnaldo L.. And the article was included in Chemistry & Biodiversity in 2019.Electric Literature of C6H12O2 This article mentions the following:

The essential oil composition of the aerial parts of Artemisia magellanica Sch. Bip. (Asteraceae), native to Patagonia, was analyzed by GC-FID-MS. This is the first report on the essential oil composition of A. magellanica. A total of 113 components were identified accounting for 95.6-95.7% of the oil. The essential oil was characterized by a high percentage of γ-costol (21.0-43.5%), selina-4,11-diene, (Z)-β-ocimene, (E)-β-farnesene, (Z)-en-yn-dicycloether and 23 different esters (28.7%). In turn, Artemisia biennis, a species native to North America, which is considered by some authors to be conspecific with A. magellanica, yielded an essential oil that was rich in (Z)-β-ocimene (34.7%), (E)-β-farnesene (40.0%) and the acetylenes (Z)- and (E)-en-yn-dicycloethers (11.0%). Thus, as A. biennis lacks the three main components present in A. magellanica, namely γ-costol, 2-methylbutyl 2-methylbutyrate and selina-4,11-diene, these compounds could be considered as potential chem. markers for A. magellanica since they are absent or only found as minor constituents in other members of the genus. The data presented herein is also useful for genus taxonomy. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5Electric Literature of C6H12O2).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C6H12O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Preparation the composite with high toughness and strength by recycled cyclic olefin copolymer was written by Sun, Ming Yang;Liu, Wen Chuan;Wu, Yuan Sheng;Qian, Hao. And the article was included in Polymer Engineering & Science in 2022.SDS of cas: 6683-19-8 This article mentions the following:

At present, it is of great significance to develop an effective method of recycling cyclic olefin copolymers (rCOC) due to its increasing application. But, its poor toughness is still an important difficulty to limit its effective recycling. In this article, we introduced PA6 into the POE-g-MAH/rCOC composites. Because of the good compatibility of POE-g-MAH between PA6 and rCOC, it just led to an overall improvement in mech. properties of PA6/POE-g-MAH/rCOC (45/15/40) composites. Its tensile strength reached 42.3 MPa, which was more than 41.9% compared with that of POE-g-MAH/rCOC composites. Its notched impact strength was 11.7 kJ/m², which was higher than 875.0% compared with rCOC. Furthermore, the component of PA6 was wrapped by nonpolar rCOC and POE-g-MAH, resulting in a low water absorption rate (1.0%). So, the strength of the composites only dropped a little after water adsorption. In summary, the addition of PA6 helped the composites effectively utilize the toughness of POE-g-MAH. Thus, we developed an easy method to recycle rCOC and prepare the responding composites with high strength and toughness. In the experiment, the researchers used many compounds, for example, 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8SDS of cas: 6683-19-8).

2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.SDS of cas: 6683-19-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A Pan Photoaffinity Probe for Detecting Active Forms of Matrix Metalloproteinases was written by Nury, Catherine;Czarny, Bertrand;Cassar-Lajeunesse, Evelyne;Georgiadis, Dimitris;Bregant, Sarah;Dive, Vincent. And the article was included in ChemBioChem in 2013.Formula: C10H14O4 This article mentions the following:

A photoaffinity probe based on the scaffold of a potent broad-spectrum phosphinic peptide inhibitor of matrix metalloproteinases (MMPs) has been developed. A photolabile diazirine group for covalent modification of MMP active forms was incorporated at the P₁‘ position, and a tritium radioactive label for the sensitive detection of MMP covalent adducts by radioimaging was attached. The probe was characterized on seven catalytic domains of human MMPs (MMP-2, -3, -8, -9, -12, -13 and -14) and was found to display nanomolar affinities toward this set of MMPs, covalently modifying them with crosslinking yields varying from 12 to 58 %, thus leading to highly sensitive detection of these MMPs. In a complex proteome complemented with four recombinant MMPs (MMP-2, -9, -12 and -13), this probe enabled their simultaneous detection with a threshold of few femtomoles and low background labeling. Those properties should make this new pan-activity-based MMP probe a valuable tool for the detection of MMP active forms from biol. fluids or tissue extracts In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Formula: C10H14O4).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C10H14O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

α-Amino ketones from amino acids as precursors for the Knorr pyrrole synthesis was written by Hamby, James M.;Hodges, John C.. And the article was included in Heterocycles in 1993.Product Details of 87694-53-9 This article mentions the following:

A useful and versatile modification of the Knorr pyrrole synthesis is described. Key α-amino ketone intermediates for the Knorr condensation were readily prepared from the N-methoxy-N-methylamides of amino acids and condensed with 1,3-dicarbonyl compounds to afford tetrasubstituted pyrroles, e.g. I, in good yields. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Product Details of 87694-53-9).

(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 87694-53-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Microwave-assisted palladium-catalyzed isonitrile insertion in 2-bromophenylureas for efficient synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines was written by Pandey, Garima;Batra, Sanjay. And the article was included in RSC Advances in 2015.Recommanded Product: 16413-26-6 This article mentions the following:

A general route to the synthesis of 4-substituted imino 4H-benzo[d][1,3]oxazin-2-amines via palladium-catalyzed isonitrile insertion in 2-bromophenylureas succeeded by a C-O cross-coupling of the intermediate imidoylpalladium species under microwave irradiation was reported. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Recommanded Product: 16413-26-6).

3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 16413-26-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Role of pretreatment and evidence for the enhanced biodegradation and mineralization of low-density polyethylene films by greater waxworm was written by Kundungal, Harsha;Gangarapu, Manjari;Sarangapani, Saran;Patchaiyappan, Arunkumar;Devipriya, Suja Purushothaman. And the article was included in Environmental Technology in 2021.Recommanded Product: 84-61-7 This article mentions the following:

The present study reports the role of pretreatment for the enhanced biodegradation of low-d. polyethylene (LDPE) with Galleria mellonella (Greater waxworm). The pretreatment of the LDPE film was carried out under solar radiation. The pretreated LDPE (PTLDPE) and untreated LDPE (UTLDPE) were characterized with AFM, FTIR and ¹H NMR techniques. The qual. anal. for the biodegradation of pretreated and untreated LDPE was examined by analyzing the Excreta residue (ER) of Galleria mellonella fed with LDPE. The mineralization of the ER of waxworm fed on Waxcomb (WC), UTLDPE and PTLDPE were studied by analyzing the changes in physiochem. properties through FTIR, ¹H NMR and GC-MS techniques in addition to weight loss percentage of PTLDPE and survival rates of the tested greater waxworms. Solar pretreatment of LDPE led to increased surface roughness which favored the waxworms to feed voraciously on PTLDPE. The post degradation studies of Waxcomb (WC), PTLDPE and UTLDPE showed 92.03 ± 2.1%, 18.57 ± 1.8% and 55.8 ± 1.2% weight loss, resp. The FTIR, ¹H NMR and GC-MS results confirm that the ER of waxworm fed on WC, UTLDPE and PTLDPE showed the presence of new carbonyl and alc. groups with increase in unsaturated hydrocarbon indicating enhanced mineralization of LDPE. The efficient mineralization of PTLDPE by waxworm was observed without affecting its survivability. A plausible mechanism of LDPE degradation has also been proposed. The rapid and cost effective biodegradation of PTLDPE through waxworm paves a new and facile route for hazardous plastic waste treatment. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Recommanded Product: 84-61-7).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 84-61-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Diastereoselective Synthesis of Rauhut-Currier-Type Adducts via an Unexpected α-Addition of α,β-Unsaturated γ-Butyrolactams to Coumarin Derivatives was written by Yang, Shu-Mei;Madhusudhan Reddy, Ganapuram;Liu, Meng-Hsien;Wang, Tzu-Ping;Yu, Jhen-Kuei;Lin, Wenwei. And the article was included in Journal of Organic Chemistry in 2017.Application In Synthesis of Ethyl 3-oxo-3-(thiophen-2-yl)propanoate This article mentions the following:

A novel, base-catalyzed and highly diastereoselective direct Michael addition-isomerization sequence is presented for the efficient synthesis of Rauhut-Currier-type adducts. An unexpected α-addition of γ-butyrolactam onto the 3-acyl coumarin derivatives was observed rather than the γ-addition, which is more common. The adducts could further undergo hydrolysis/decarboxylation to generate the products which are equivalent to those obtained by α-addition of γ-butyrolactam onto the corresponding chalcones. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Application In Synthesis of Ethyl 3-oxo-3-(thiophen-2-yl)propanoate).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application In Synthesis of Ethyl 3-oxo-3-(thiophen-2-yl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Simultaneous chemical and sensory analysis of domestic cat urine and feces with headspace solid-phase microextraction and GC-MS-olfactometry was written by Banik, Chumki;Koziel, Jacek A.;Li, James Z.. And the article was included in Separations in 2021.HPLC of Formula: 868-57-5 This article mentions the following:

The association between humans and cats (Felis catus) is well known. This domestic animal is also known for its malodorous urine and feces. The complexity of the odorous urine and feces impacts human life by triggering the human sensory organ in a neg. way. The objective of this research was to identify the volatile organic chems. (VOCs) and associated odors in cat urine and feces using gas chromatog.-mass spectrometry and simultaneous sensory anal. of fresh and aged samples. The solid-phase microextraction (SPME) technique was used to preconc. the VOCs emitted from urine or feces samples. Twenty-one compounds were identified as emitted from fresh urine, whereas 64 compounds were emitted from fresh feces. A contrasting temporal impact was observed in the emission of VOCs for urine and feces. On aging, the emission increased to 34 detected chems. for stale urine, whereas only 12 chems. were detected in stale feces. Not all compounds were malodorous; some compounds had a pleasant hedonic smell to the human nose. Although trimethylamine, low-mol.-weight organic acids, and ketones were contributors to the odor to some extent, phenolic compounds and aromatic heterocyclic organic N compounds generated the most intense odors and substantially contributed to the overall malodor, as observed by this study. This work might be useful to formulate cat urine and feces odor remediation approaches to reduce odor impacts. In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5HPLC of Formula: 868-57-5).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.HPLC of Formula: 868-57-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Catalytic asymmetric allylic alkylation in water with a recyclable amphiphilic resin-supported P,N-chelating palladium complex was written by Uozumi, Yasuhiro;Shibatomi, Kazutaka. And the article was included in Journal of the American Chemical Society in 2001.Related Products of 20637-09-6 This article mentions the following:

The PS-PEG resin-bound [(diphenylphosphino)phenyl]pyrroloimidazolones I and II (R = H, HO; Q = polystyrene resin) were prepared and formed palladium complexes with [PdCl(η³-C₃H₅)]₂. These immobilized complexes were catalysts for the asym. allylic alkylation of both cyclic and acyclic α,β-unsaturated carbonates in water with enantioselectivities up to 98% ee. Thus, reaction of the cyclohexenyl carbonate III with di-Me malonate in H₂O containing Li₂CO₃ and the complex I-[PdCl(η³-C₃H₅)]₂ gave (S)-cyclohexenylmalonate IV in 78% yield and 89% enantiomeric excess. In the experiment, the researchers used many compounds, for example, Methyl 4-(4-aminophenyl)butanoate (cas: 20637-09-6Related Products of 20637-09-6).

Methyl 4-(4-aminophenyl)butanoate (cas: 20637-09-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Related Products of 20637-09-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics