Esters-buliding-blocks

Anitha, Rajan published the artcileAnti-corrosive potential of Cyperus rotundus as a viable corrosion inhibitor for mild steel in sulphuric acid, Formula: C7H12O3, the main research area is cyperus rotundus mild steel sulfuric acid corrosion inhibitor.

Over the past decade, plant extracts are ultimate green candidatures to substitute the expensive and noxious synthetic corrosion inhibitors. In this regard, this study aims to focus on evaluating anti-corrosion properties of green inhibitor Cyperus rotundus (C. rotundus), a perennial herb found throughout India. Design/methodol./approach: The biocompatible components present in C. rotundus extract was analyzed by gas chromatog.-mass spectroscopy anal. Findings: Predominant components such as octadecanoicacid, ethylester, n-hexadecanoic acid, pentanoicacid-4-oxoethyl ester, cyclotrisiloxane, hexamethyl, cyclotetrasiloxane and octamethyl were identified from the extract of C. rotundus. Impedance study demonstrated that the addition of inhibitor reduces the double-layer capacitance and increases the charge transfer resistance. Furthermore, polarization studies indicated that the extract of C. rotundus acted as a mixed-type inhibitor with decrease in corrosion c.d. with increase in concentration AFM study evinced the formation of inhibitor film on mild steel surface. The donor-acceptor interactions of active sites of predominant phytoconstituents were substantiated by computational anal. (DFT). Originality/value: This paper deals with the inhibition effect of extract of C. rotundus on mild steel in 0.5M H2SO4. C. rotundus has a capability to adsorb on the metal surface, thus hindering corrosion.

Pigment & Resin Technology published new progress about Band gap. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Formula: C7H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Beilin published the artcileNovel drug targets for treatment of cryptosporidiosis, Recommanded Product: 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, the main research area is review nitazoxanide cryptosporidiosis HIV; Cryptosporidium; cryptosporidiosis; drug targets; protozoa.

IntroductionCryptosporidiumspecies are protozoan parasites that are important causes of diarrheal disease including waterborne outbreaks, childhood diarrhea in resource-poor countries, and diarrhea in compromised hosts worldwide. Recent studies highlight the importance of cryptosporidiosis in childhood diarrhea, malnutrition, and death in resource-poor countries. Despite this, only a single drug, nitazoxanide, has demonstrated efficacy in human cryptosporidiosis and its efficacy is limited in malnourished children and patients with HIV. Areas coveredIn this review, we highlight work on potential targets for chemotherapy and review progress on drug development. A number of new targets have been identified for chemotherapy and progress has been made at developing drugs for these targets. Targets include parasite kinases, nucleic acid synthesis and processing, proteases, and lipid metabolism Other groups have performed high-throughput screening to identify potential drugs. Several compounds have advanced to large animal studies. Expert opinionDevelopment of drugs for cryptosporidiosis has been plagued by a lack of success. Barriers have included poor correlations between in vitro activity and clin. success as well as frequent unanticipated adverse effects. Without a clear pathway forward, it is wise to maintain a diverse development pipeline. Drug developers should also realize that success will likely require a sustained, methodical effort.

Expert Opinion on Therapeutic Targets published new progress about Animalia. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, Recommanded Product: 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ding, Lianqin published the artcileAn in vivo and in vitro model on the protective effect of corilagin on doxorubicin-induced cardiotoxicity via regulation of apoptosis and PI3-K/AKT signaling pathways, Synthetic Route of 2044-85-1, the main research area is corilagin doxorubicin cardiotoxicity apoptosis AKT signaling pathway oxidative stress; H9c2 cells; PI3-K/AKT; apoptosis; cardiotoxicity; corilagin; doxorubicin.

Globally, doxorubicin (DOX)-induced cardio dysfunction is a serious cause of morbidity and mortality in cancerous patients. An adverse event of cardiotoxicity is the main deem to restrict in the clin. application by oncologists. Corilagin (CN) is well known for its antioxidative, anti-fibrosis, and anticancer effects. Herein, we aimed to evaluate the action of CN on DOX-induced exptl. animals and H9c2 cells. The myocardium-specific marker, CK-MB, and the influx of mitochondrial calcium levels were measured by using com. kits. Biochem. indexes reflecting oxidative stress and antioxidant attributes such as malondialdehyde, glutathione peroxidase, reduced glutathione, superoxide dismutase, and catalase were also analyzed in DOX-induced cardiotoxic animals. In addition, mitochondrial ROS were measured by DCFH-DA in H9c2 cells under fluorescence microscopy. DOX induction significantly increased oxidative stress levels and also modulated apoptosis/survival protein expressions in myocardial tissues. Western blots were used to measure the expressional levels of Bax/Bcl-2, caspase-3, PI3-K/AKT, and PPARγsignaling pathways. Histol. studies were executed to observe morphol. changes in myocardial tissues. All of these DOX-induced effects were attenuated by CN (100 mg/kg bw). These in vitro and in vivo results point towards the fact that CN might be a novel cardioprotective agent against DOX-induced cardiotoxicity through modulating cardio apoptosis and oxidative stress.

Journal of Biochemical and Molecular Toxicology published new progress about Animalia. 2044-85-1 belongs to class esters-buliding-blocks, name is 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, and the molecular formula is C24H14Cl2O7, Synthetic Route of 2044-85-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Erukainure, Ochuko L. published the artcileL-leucine stimulation of glucose uptake and utilization involves modulation of glucose – lipid metabolic switch and improved bioenergetic homeostasis in isolated rat psoas muscle ex vivo, Related Products of esters-buliding-blocks, the main research area is leucine glucose lipid metabolism bioenergetic homeostasis; Glucose-uptake; Glucose–Lipid switch; Leucine; Metabolomics; Type 2 diabetes.

The antidiabetic effect of l-leucine has been attributed to its modulatory effect on glucose uptake and lipid metabolism in muscles. However, there is a dearth on its effect on glucose metabolism in muscles. Thus, the present study investigated the effect of l-leucine – stimulated glucose uptake on glucose metabolism, dysregulated lipid metabolic pathways, redox and bioenergetic homeostasis, and proteolysis in isolated psoas muscle from Sprague Dawley male rats. Isolated psoas muscles were incubated with l-leucine (30-240 μg/mL) in the presence of 11.1 mMol glucose at 37 C for 2 h. Muscles incubated in only glucose served as the control, while muscles not incubated in l-leucine and/or glucose served as the normal control. Metformin (6.04 mM) was used as the standard antidiabetic drug. Incubation with l-leucine caused a significant increase in muscle glucose uptake, with an elevation of glutathione levels, superoxide dismutase, catalase, E-NTPDase and 5′nucleotidase activities. It also led to the depletion of malondialdehyde and nitric oxide levels, ATPase, chymotrypsin, acetylcholinesterase, glycogen phosphorylase, glucose-6-phosphatase, fructose-1,6-bisphosphatase and lipase activities. There was an alteration in lipid metabolites, with concomitant activation of glycerolipid metabolism, fatty acid metabolism, and fatty acid elongation in mitochondria in the glucose-incubated muscle (neg. control). Incubation with l-leucine reversed these alterations, and concomitantly deactivated the pathways. These results indicate that l-leucine-enhanced muscle glucose uptake involves improved redox and bioenergetic homeostasis, with concomitant suppressed proteolytic, glycogenolytic and gluconeogenetic activities, while modulating glucose – lipid metabolic switch.

Amino Acids published new progress about Animalia. 41114-00-5 belongs to class esters-buliding-blocks, name is Ethyl pentadecanoate, and the molecular formula is C17H34O2, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Onkarappa, Sharath Bandibairanahalli published the artcilePreparation of alkyl levulinates from biomass-derived 5-(halomethyl)furfural (X = Cl, Br), furfuryl alcohol, and angelica lactone using silica-supported perchloric acid as a heterogeneous acid catalyst, Quality Control of 539-88-8, the main research area is alkyl levulinate halomethylfurfural furfuryl alc lactone silica perchloric acid; biomass heterogeneous acid catalyst.

This work reports the synthesis of a series of alkyl levulinates from biomass-derived 5-(halomethyl)furfural (X = Cl, Br), furfuryl alc., and angelica lactone using silica-supported perchloric acid (HClO4-SiO2) as a heterogeneous acid catalyst. The solvent-free, one-pot preparation afforded levulinate esters in excellent isolated yields (> 84%). The reactions were performed at 120 °C for 6 h in a batch-type glass pressure reactor using XMF and furfuryl alc. in presence of excess of the alc. reagent and 4 weight% of the HClO4-SiO2 catalyst (0.028 mmol HClO4). Furthermore, the reaction protocol was extended for the synthesis of ALs starting with angelica lactone at 90 °C for 2 h in a round-bottomed flask by using excess alc. and 4 weight% of the HClO4-SiO2 catalyst.

Biomass Conversion and Biorefinery published new progress about Angelica. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Quality Control of 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Xinran published the artcileIdentification of changes in volatile compounds in sea cucumber Apostichopus japonicus during seasonings soaking using HS-GC-IMS, Formula: C9H10O2, the main research area is volatile compound Apostichopus japonicus gas chromatog ion mobility spectrometry.

The flavor fingerprint of sea cucumbers was developed and volatile compounds were investigated by HS-GC-IMS. A total of 73 typical target compounds were identified. The differences of flavor compounds in sea cucumbers from different seasonings soaking samples areas were observed After soaking, the concentration of compounds such as 1-octen-3-one and 3-methyl-2-butanol in sea cucumbers were decreased, while the concentration of representative flavor compounds in seasonings such as β-ocimene, linalool and furaneol were increased. Subsequently, PCA was performed based on the signal intensity of the identified flavor compounds, and the results clearly showed that the sea cucumbers without seasonings group and seasonings-soaked sea cucumbers samples in a relatively independent space would be well distinguished. The results showed that the flavor fingerprint of sea cucumbers was established by HS-GC-IMS and PCA based on the identified volatile compounds

LWT–Food Science and Technology published new progress about Analysis. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Formula: C9H10O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Alabi, Okunola A. published the artcileIn vitro cytotoxicity of co-exposure to superparamagnetic iron oxide and solid lipid nanoparticles, Synthetic Route of 2044-85-1, the main research area is superparamagnetic iron oxide solid lipid nanoparticle cytotoxicity co exposure; Superparamagnetic iron oxide nanoparticles; co-exposure; cytotoxicity; in vitro study; solid lipid nanoparticles.

Increased production and use of different types of nanoparticles (NPs) in the last decades has led to increased environmental release of these NPs with potential detrimental effects on both the environment and public health. Information is scarce in the literature on the cytotoxic effect of co-exposure to many NPs as this concern is relatively recent. Thus, in this study, we hypothesized scenarios of cell′ s co-exposure to two kinds of NPs, solid lipid nanoparticles (SLNs) and superparamagnetic iron oxide nanoparticles (SPIONs), to assess the potential cytotoxicity of exposure to NPs combination. Cytotoxicity of SPIONs, SLNs, and their 1:1 mixture (MIX) in six tumor and six non-tumor cell lines was investigated. The mechanisms underlining the induced cytotoxicity were studied through cell cycle anal., detection of reactive oxygen species (ROS), and alterations in mitochondrial membrane potential (ΔΨM). Double staining with acridine orange and ethidium bromide was also used to confirm cell morphol. alterations. The results showed that SPIONs induced low cytotoxicity compared to SLNs. However, the mixture of SPIONs and SLNs showed synergistic, antagonistic, and additive effects based on distinct tests such as viability assay, ROS generation, ΔΨM, and DNA damage, depending on the cell line. Apoptosis triggered by ROS and disturbances in ΔΨM are the most probable related mechanisms of action. As was postulated, there is possible cytotoxic interaction between the two kinds of NPs.

Toxicology and Industrial Health published new progress about Analysis. 2044-85-1 belongs to class esters-buliding-blocks, name is 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, and the molecular formula is C24H14Cl2O7, Synthetic Route of 2044-85-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Pei-Xia published the artcileChemical constituents analysis of ethyl acetate extract from MSR-1707 by GC-MS, SDS of cas: 929-77-1, the main research area is chem constituent analysis ethyl acetate extract MSR.

To analyze the chem. constituents of Et acetate extract from MSR-1707 to promote the rational utilization of the mushroom resources. MSR-1707 belongs to the genus Nigrospora sp. It was extracted by Et acetate, then the extract was analyzed by Gas Chromatog.-Mass Spectrometer (GC-MS). Identification of compounds was achieved according to their GC retention indexes (RI) and database search using the library of NIST05, as well as a comparison of the fragmentation pattern of the mass spectra with data published in the literature. Seventy-three compounds were separated by gas chromatog. Based on the NIST05 spectral library and corresponding literature information, fifty-three compounds were identified. Their relative percentage of contents accounted for 95.62% of the outflow peak. Some of the identified peaks are 9-Octadecenoic acid, Me ester(E)(18.50%),9-Tricosene(Z)(8.30%), 13-Docosenamide (E)(5.26%) and Myristic acid glycidyl ester (3.11%). This is the first report of chem. constituents of the Et acetate extract of Nigrospora sp. using GC-MS, which offer some theor. basis for the further exploration and application of this mushroom.

Asian Journal of Biology published new progress about Analysis. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, SDS of cas: 929-77-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Karabagias, Ioannis K. published the artcilePhysico-chemical parameters complemented with aroma compounds fired up the varietal discrimination of wine using statistics, Computed Properties of 106-32-1, the main research area is wine elec conductivity phenolic compound salinity.

Wine comprises a beloved food and human companion since the early times of humans on earth. In this study, wine samples of different type (red, white, and rose) and variety (Agiorgitiko, Augoustiatis, Cabernet Sauvignon, Syrah, Vlahiko, Assyrtiko, Chardonnay, Debina, Moschofilero, Vidiano, Syrah plus Mandilari, and Xinomavro) were subjected to physico-chem. and aroma compounds analyses, in an effort to characterize their identity and discriminate these samples according to variety using statistics. Results showed significant differences (p < 0.05) for wine samples of different variety in regard to the measured physico-chem. parameters (pH, elec. conductivity, total dissolved solids, salinity, L*, a*, b*, and Chroma*) and aroma compounds (alcs., esters, phenolic compounds, pyran compounds, and terpenoids/norisoprenoids). Application of multivariate anal. of variance, linear discriminant anal., and weighted least-squares regression anal. fired up the perfect varietal discrimination (100%) of wine samples and modeling of results, contributing to new information in the literature about the identity of these wine varieties. European Food Research and Technology published new progress about Alcohols. 106-32-1 belongs to class esters-buliding-blocks, name is Ethyl octanoate, and the molecular formula is C10H20O2, Computed Properties of 106-32-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lopes, Ana Claudia Alencar published the artcileImpact of Saccharomyces cerevisiae single inoculum and mixed inoculum with Meyerozyma caribbica on the quality of mead, Recommanded Product: Ethyl nonanoate, the main research area is Meyerozyma Saccharomyces single inoculum mead quality.

The sensory quality of fermented beverages, such as mead, is directly related to the raw material, microorganisms, and production process. The aim of this study was to evaluate the impact of Saccharomyces cerevisiae as single inoculum and co-inoculated with Meyerozyma caribbica on the physicochem. and sensory quality of mead. The meads were characterized according to their sugar, ethanol, furfural, hydroxymethylfurfural, Et carbamate, phenolics, volatile compounds, and sensory profile. Both starter cultures showed good fermentative capacity, resulting in beverages with 12% (w/v) alc. content. 4-Methylumbelliferone and gallic acid were the most abundant phenolic compounds detected in both beverages. Et carbamate was not detected; furfural detected below the quantification limit and 5-hydroxymethylfurfural was not higher than 0.3 mg/L. In general, unlike expected, the mixed inoculum resulted in a reduction of the volatile compounds The mead produced with S. cerevisiae presented 1403.3 μg/L of esters and while mixed inoculum, 1084 μg/L. This result impacted the sensory anal., in which the scores for flavor, aroma, and purchase intention were slightly higher for the mead produced with S. cerevisiae, although there was no statistical difference from the mixed inoculum. The results of this work indicate that further studies, such as on the adequacy of the must composition, are necessary for a better understanding of the potential of the used mixed inoculum.

European Food Research and Technology published new progress about Alcohols. 123-29-5 belongs to class esters-buliding-blocks, name is Ethyl nonanoate, and the molecular formula is C11H22O2, Recommanded Product: Ethyl nonanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics