Esters-buliding-blocks

Shao, Changdong published the artcileOxalic acid as the in situ carbon monoxide generator in palladium-catalyzed hydroxycarbonylation of arylhalides, Recommanded Product: 3-(Methoxycarbonyl)benzoic acid, the publication is Organic & Biomolecular Chemistry (2017), 15(23), 5033-5040, database is CAplus and MEDLINE.

An efficient palladium-catalyzed hydroxycarbonylation reaction of arylhalides using oxalic acid as a CO source was developed. The reaction features high safety, low catalyst loading, and a broad substrate scope, and provided a safe and tractable approach to access a variety of aromatic carboxylic acid compounds Mechanistic studies revealed the decomposition pattern of oxalic acid.

Organic & Biomolecular Chemistry published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C7H5Cl2NO, Recommanded Product: 3-(Methoxycarbonyl)benzoic acid.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Garcia, Caroline A. published the artcileEffects of crude protein and sodium intake on water turnover in cats fed extruded diets, SDS of cas: 121-79-9, the publication is Journal of Animal Physiology and Animal Nutrition (2021), 105(S2), 95-105, database is CAplus and MEDLINE.

The comprehension of strategies to increase urine production may be important, especially in kibble diets to prevent urolithiasis in cats. The effects of increasing amounts of crude protein (CP) and sodium on the water turnover of cats were evaluated using the water balance (WB) method and the deuterium dilution technique. The study followed a randomized block design, with three blocks of eight cats, two cats per food type in each block, and six cats per food. Four extruded diets with different amounts of CP and sodium were evaluated (on DM basis): 28% CP and 0.58% sodium; 39% CP and 0.64% sodium; 52% CP and 0.76% sodium; and 64% CP and 0.87% sodium. Cats were individually housed in cages for 8 days to measure WB, urea excretion, and faecal and urine characteristics. Deuterium oxide was used to evaluate water turnover, and during the period cats were housed in a collective cattery. The data were analyzed by an F test, and the means were compared by polynomial contrasts. The level of significance was set at 0.05. The methods were compared by Pearson correlation, and Bland and Altman anal. The increase in the CP content elevated linearly the renal excretion of urea (p < .001), and, together with the higher sodium intake, elevated the renal solute load, which resulted in a linear increase in urine production and water intake (p < .01). The urine d., metabolic water, and faecal and insensible water losses did not differ (p > .05). The water flux increased linearly when using the deuterium method (p < .001), but the obtained values were 20.85 ± 11.11 mL/cat/day higher than those verified using the WB method (p = .001). Higher CP and sodium amounts in dry diets increased the urine production and water consumption of cats, and this can be explored as a possible option to increase urination.

Journal of Animal Physiology and Animal Nutrition published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, SDS of cas: 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hernandez-Fernandez, Joaquin published the artcileExperimental study of the auto-catalytic effect of triethylaluminum and TiCl₄ residuals at the onset of non-additive polypropylene degradation and their impact on thermo-oxidative degradation and pyrolysis, COA of Formula: C42H63O3P, the publication is Journal of Analytical and Applied Pyrolysis (2021), 105052, database is CAplus.

In this article, the pyrolysis and thermo-oxidative degradation of five industrial waste products was carried out in a discontinuous quartz reactor at 550°C under the auto-catalytic effect of residues of titanium tetrachloride, triethylaluminium (TEAL), and iron (Fe). We using the coupled on-site anal. of an GC-MS/FID/PDHID with 7 valves and 8 columns in series. The study also discusses the effect of the concentration of the catalyst residuals with the Eac (activation energy) and the evolution of the profile of permanent oxygenated gases, hydrocarbons and sulfurs, as well as the functional waste groups from decomposition during pyrolysis and thermo-oxidative degradation The origin of the degradation and the beginnings of PP pyrolysis and thermo-oxidative degradation are explained by hydrolysis mechanisms and thermal reactions that imply successive reactions with these (TEAL), TiO₂, and chloride residues, giving rise to Et radicals and explaining the formation of alcs., ketones, carboxylic acids, alkynes and alkenes. The study also found that the gaseous profiles are very consistent with the DTG curves and the Eac, in terms of the appearance of peaks and relevant stages throughout the total temperature range. The effect of Cl, Fe and TEAL on the PP degradation is very high upon passing from an inert to an oxidative atm. This reduces the content of hydrocarbons and oxygenates to CO₂ between 49 and 66% because of the attack of the oxygen atom. In the pyrolysis the propylene content oscillates between 42 and 56%.

Journal of Analytical and Applied Pyrolysis published new progress about 31570-04-4. 31570-04-4 belongs to esters-buliding-blocks, auxiliary class Mono-phosphine Ligands, name is Tris(2,4-di-tert-butylphenyl) phosphite, and the molecular formula is C42H63O3P, COA of Formula: C42H63O3P.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

de Souza, Alana Gomes published the artcileNeuroprotective effects of dimethyl fumarate against depression-like behaviors via astrocytes and microglia modulation in mice: possible involvement of the HCAR2/Nrf2 signaling pathway, Application of Dimethyl fumarate, the publication is Naunyn-Schmiedeberg’s Archives of Pharmacology, database is CAplus and MEDLINE.

We postulated that di-Me fumarate (DMF) exerts neuroprotective effects against depression-like behaviors through astrocytes and microglia modulation. To ascertain our hypothesis and define the mechanistic pathways involved in effect of DMF on neuroinflammation, we used the depression model induced by chronic unpredictable mild stress (CUMS), in which, the mice were exposed to stressful events for 28 days and from the 14th day they received DMF in the doses of 50 and 100 mg/kg or fluoxetine 10 mg/kg or saline. On the 29th day, the animals were subjected to behavioral tests. Microglia (Iba1) and astrocyte (GFAP) marker expressions were evaluated by immunofluorescence analyzes and the cytokines TNF-α and IL-Iβ by immunoenzymic assay. In addition, computational target prediction, 3D protein structure prediction, and docking calculations were performed with monomethyl fumarate (DMF active metabolite) and the Keap1 and HCAR2 proteins, which suggested that these could be the probable targets related protective effects. CUMS induced anxiety- and depressive-like behaviors, cognitive deficit, decreased GFAP, and increased Iba1, TNF-α, and IL-Iβ expression in the hippocampus. These alterations were reversed by DMF. Thus, it is suggested that one of the mechanisms involved in the antidepressant effect of DMF is neuroinflammatory suppression, through the signaling pathway HCAR2/Nrf2. However, more studies must be performed to better understand the mol. mechanisms of this drug.

Naunyn-Schmiedeberg’s Archives of Pharmacology published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C6H8O4, Application of Dimethyl fumarate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Feng, Yunchao published the artcileHighly dispersed Co/N-rich carbon nanosheets for the oxidative esterification of biomass-derived alcohols: Insights into the catalytic performance and mechanism, Quality Control of 103-26-4, the publication is Journal of Catalysis (2021), 148-155, database is CAplus.

Developing the active and environmentally friendly non-noble nano-catalysts is highly desired to transform biomass-derived platform into value chems. Herein, we report a low-cost and sustainable cobalt/nitrogen-doped carbon catalyst containing both metallic Co and Co-N components exhibits satisfying activity for the oxidative esterification of 5-hydroxymethylfurfural and other investigated alcs. in methanol without the base additive under mild conditions. Exptl. results show that an appropriate ratio of Co to Co-N is responsible for the high activity of the Co/Co-N/CN catalysts towards oxidative esterification. Theor. computational results demonstrate that the Co/Co-N group synergistically promotes electron transfer from the Co adatom to the surface oxygen atoms, facilitates O₂ adsorption and activation on the Co sites, and further reduces the energy barrier for the oxidation of alcs. to aldehydes, all of which contribute to the overall activity of oxidative esterification of alcs. to the corresponding esters. In addition to exhibiting superior intrinsic activity, the as-prepared Co/Co-N/CN catalyst also shows excellent stability and recyclability.

Journal of Catalysis published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, Quality Control of 103-26-4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Larina, Nina A. published the artcileSynthesis and photochromism of a series of new 2-unsubstituted 3-(2-benzylbenzoyl)quinolin-4(1H)-ones, SDS of cas: 924-99-2, the publication is Tetrahedron (2010), 66(42), 8291-8299, database is CAplus.

Synthesis and characterization of a series of new 2-unsubstituted 3-(2-benzylbenzoyl)quinolin-4(1H)-ones is described. In addition to their potential biol. activity, these compounds exhibit photoreversible photochromic properties in anaerobic conditions. Using the 1 and 2D NMR techniques we demonstrated that the coloration occurred owing to the formation of fluorescent 5a,6-dihydrobenzo[b]acridin-(5H)-ones. The photoreaction is stereoselective and the S,R-isomers are the major products (83%) whereas the S,S-isomers are the minor (6%). In addition, the irreversible formation of two oxidation products, 3-(2-benzoylbenzoyl)quinolin-4(1H)-ones, and acridin-12(5H)-one derivatives was observed in the presence of air.

Tetrahedron published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, SDS of cas: 924-99-2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Edwards, David R. published the artcileCatalytic Proficiency: The Extreme Case of S-O Cleaving Sulfatases, Application of Potassium 4-nitrophenyl sulfate, the publication is Journal of the American Chemical Society (2012), 134(1), 525-531, database is CAplus and MEDLINE.

As benchmarks for judging the catalytic power of sulfate monoesterases, we sought to determine the rates of spontaneous hydrolysis of unactivated alkyl sulfate monoesters by S-O bond cleavage. Neopentyl sulfate proved to be unsuitable for this purpose, since it was found to undergo hydrolysis by a C-O bond cleaving mechanism with rearrangement of its carbon skeleton. Instead, we examined the temperature dependence of the spontaneous hydrolyzes of aryl sulfate monoesters, which proceed by S-O cleavage. Extrapolation of a Bronsted plot [log(k₂₅^N) = (-1.81 ± 0.09) pK_a^LG + (3.6 ± 0.7)] based on the rate constants at 25 °C for hydrolysis of a series of sulfate monoesters to a pK_a^LG value of 16.1, typical of an aliphatic alc., yields k₂₅^N = 3 × 10^-26 s^-1. Comparison of that value with established k_cat values of bacterial sulfatases indicates that these enzymes produce rate enhancements (k_cat/k_uncat) of up to 2 × 10²⁶-fold for the hydrolysis of sulfate monoesters. These rate enhancements surpass by several orders of magnitude the ∼10²¹-fold rate enhancements that are generated by phosphohydrolases, the most powerful biol. catalysts previously known. The hydrolytic rates of phosphate and sulfate monoesters are compared directly, and the misleading impression that the two classes of ester are of similar reactivity is dispelled.

Journal of the American Chemical Society published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Application of Potassium 4-nitrophenyl sulfate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lee, Ting-Lei published the artcilePhotoresponsive and fluorescence behaviors of azobenzene-containing amphiphilic block copolymers, Product Details of C23H28N2O4, the publication is Journal of Polymer Science, Part B: Polymer Physics (2017), 55(10), 793-803, database is CAplus.

The effects of solvency and mole fraction of azobenzene moieties (f_PAzoMA) on the photoresponsive and fluorescence behaviors of poly(acrylic acid)-block-poly(6-[4-(4′-methoxyphenylazo)phenoxy]hexyl methacrylate) (PAA-PAzoMA) amphiphilic diblock copolymers were investigated using UV-vis spectroscopy and fluorescence spectroscopy. The photoresponsive behavior depended strongly on the solvency and f_PAzoMA. When dissolved in a PAA-selective solvent, PAA-PAzoMA formed micelles with PAzoMA in the micelle core. The confinement of azobenzene moieties caused a steric hindrance, thereby markedly reducing the kinetics of photoisomerization compared with that of the unconfined PAA-PAzoMA in a nonselective solvent. Addnl., PAA-PAzoMA dissolved in the PAA-selective solvent caused a blue shift of the maximum absorbance, suggesting the formation of H-aggregates of azobenzene mesogens. The high H-aggregate content substantially reduced the fluorescence emission. Consequently, the fluorescence emission of PAA-PAzoMA in the nonselective solvent was more intense than that in the PAA-selective solvent. Upon UV irradiation, the enhanced bent-shaped cis isomers disturbed the compact packing of azobenzene mesogens, which substantially enhanced the fluorescence emission. Both the photoisomerization rate and fluorescence emission decreased with an increase in f_PAzoMA. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2017.

Journal of Polymer Science, Part B: Polymer Physics published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C23H28N2O4, Product Details of C23H28N2O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Gupton, John T. published the artcileReaction of Gold’s reagent with activated methylene groups derived from esters and nitroarenes, Application of Ethyl 3-(dimethylamino)acrylate, the publication is Synthetic Communications (1982), 12(12), 939-46, database is CAplus.

Acetate and malonate esters reacted with Me₂NCH:NCH:N⁺Me₂ Cl^– (I) to yield RC(:CHNMe₂)CO₂Et (R = H, Ph, CO₂Et, cyano). Similarly prepared, from nitrotoluenes and lactones, were II (R = H, Br, Cl, NO₂; R¹ = NO₂, H) and III (R = H, Me). Thus, PhCH₂CO₂Et was treated with I and NaOEt in EtOH to give PhC(:CHNMe₂)CO₂Et.

Synthetic Communications published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Application of Ethyl 3-(dimethylamino)acrylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhao, Man-Tong published the artcileGallic acid and its alkyl esters emerge as effective antioxidants against lipid oxidation during hot air drying process of Ostrea talienwhanensis, Safety of Propyl 3,4,5-trihydroxybenzoate, the publication is LWT–Food Science and Technology (2021), 110551, database is CAplus.

The antioxidant efficiency of gallic acid (GA) and its alkyl esters including Me gallate (MG), Et gallate (EG), Pr gallate (PG), Bu gallate (BG), octyl gallate (OG), lauryl gallate (LG), hexadecyl gallate (HG), and octadecyl gallate (SG) in oyster tissue during hot-air drying process was investigated. Results indicated that GA and its alkyl esters all could effectively retard lipid oxidation in oyster tissue according to peroxide value (POV), thiobarbituric acid reactive substances (TBARS) and free radical intensity. The antioxidant effects increased with the alkyl chain length until OG, thereafter, it gradually decreased. The POV of the OG treated oysters post 10 h of drying was 66.26, 68.90, 77.86, 92.61, 89.45, 70.79, 68.96 and 62.70%, resp., of those treated by GA, MG, EG, PG, BG, LG, HG and SG. The corresponding values for TBARS were 68.72, 76.59, 77.88, 84.32, 86.23, 68.31, 81.24, 77.36%, while 41.19, 58.62, 62.83, 64.49, 69.60, 61.44, 60.05 and 72.61% for free radical intensity. Pearson correlation anal. showed a pos. correlation between the antioxidant effects and the concentrations of the polyphenol compounds in oyster tissue. This report will provide the basic data for selection of suitable antioxidants to improve the oxidation stability of seafood during thermal processing.

LWT–Food Science and Technology published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C6H8O4, Safety of Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics