Esters-buliding-blocks

Arnold, Michelle E. published the artcileMicrophase-Separated Block Copolymers Comprising Low Surface Energy Fluorinated Blocks and Hydrophilic Blocks: Synthesis and Characterization, Category: esters-buliding-blocks, the publication is Macromolecules (2002), 35(9), 3697-3707, database is CAplus.

The synthesis and characterization of diblock and triblock copolymers produced by a two-component iniferter system is reported. These materials, designed for possible water treatment applications, consist of a hydrophilic poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) block and a very low surface energy poly(1,1′-dihydroperfluorooctyl methacrylate) (PFOMA) or poly(1,1,2,2-tetrahydroperfluorooctyl acrylate) (PTAN) block. Angle-dependent X-ray spectroscopy results and water contact angle measurements indicate that the surfaces of PDMAEMA-b-PFOMA diblock copolymers consist primarily of PFOMA. Transmission electron microscopy reveals that the block copolymers are microphase-separated, exhibiting either cylindrical or layered morphologies that do not change appreciably upon exposure to water. Both water uptake and water flux increase with increasing PDMAEMA content.

Macromolecules published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nagarkar, Rahul A. published the artcileEfficient Process for the Production of Alkyl Esters, Application of Dimethyl adipate, the publication is ACS Omega (2022), 7(32), 28129-28137, database is CAplus.

This article reports a scalable process development for the production of alkyl esters through the esterification route by utilizing fly ash as a catalyst. The catalyst consisting of mixed oxides such as alumina, iron oxide, calcium oxide, magnesium oxide, and silica was employed for the esterification reaction without modification. The catalyst was evaluated for the conversion of feedstock containing variable amounts of free fatty acids, mono/dibasic acid, and alc./polyols into the corresponding alkyl esters. Three types of fly ash catalysts, viz., FS-1, FP-1, and FC-1, were chosen from three different industrial sources. Synthesis of di-Me adipate was studied as a model reaction. FS-1 fly ash gave the highest yield of di-Me adipate, whereas FC-1 gave a low yield of di-Me adipate. The recyclability of FS-1 was evaluated for three cycles, and no loss of yield was observed Furthermore, the catalyst FS-I was found to be capable of producing good yields for various esterification reactions with different substrates.

ACS Omega published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Application of Dimethyl adipate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Skalicka, M. published the artcileContents of Selected Elements in the Blood Serum of Broiler Chickens After Supplementation of Humic Substances, Application of Propyl 3,4,5-trihydroxybenzoate, the publication is Folia Veterinaria (2022), 66(2), 46-53, database is CAplus.

This study was conducted to determine the concentrations of mineral substances, such as: calcium (Ca), magnesium (Mg), copper (Cu), and zinc (Zn); in the blood serum of broiler chicks after supplementation of humic substances. Group 1 (G1) was supplemented with 0.7% Humac Natur Mycosorb (HNMy); G2 with 0.7% Humac Natur Monogastric (HNM); G3 with 0.3% HNMy; and the control group (GC) received a basal diet without any supplements. In the G2 group, the serum Ca level increased slightly compared to the other exptl. groups. A statistically significant decrease (P < 0.001) in the blood serum of Mg was detected in the broilers from group G2 (0.60 mmol.l^-1) and G1 (P < 0.05; 0.68 mmol.l^-1) in comparison to the GC. The Zn in the blood serum of broilers from group G2 (22.05μmol.l^-1) was significantly increased (P < 0.05) in broilers from group G2 in comparison to the control group (19.47μmol.l^-1) and G1 group (19.61μmol.l^-1). The serum Cu (12.72μmol.l^-1) was significantly increased (P < 0.001) in broilers from group G2 in comparison to the GC (10.28μmol.l^-1). In the group G1 there was a significant decrease (P < 0.05) in the level of the Cu in the blood serum (8.69μmol.l^-1) in comparison to the serum Cu in broilers from groups G3 (10.45μmol.l^-1) and G2 (12.72μmol.l^-1). The addition of Humac Natur Mycosorb (0.3% and 0.7%) in the feed caused a strong correlation in the blood serum between the Ca and Mg (r = 0.7494; r = 0.7648). The addition of 0.3% Humac Natur Mycosorb in the feed caused a high neg. correlation (r = -0.7078) in the blood serum between the Mg and Zn.

Folia Veterinaria published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C19H17N2NaO4S, Application of Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Teixeira, Natercia published the artcileIn-depth phenolic characterization of iron gall inks by deconstructing representative Iberian recipes, Recommanded Product: Methyl 3-phenyl-2-propenoate, the publication is Scientific Reports (2021), 11(1), 8811, database is CAplus and MEDLINE.

Iron-gall ink is one of the most important inks in the history of western civilization. The deep black color results from Fe³⁺ complexes with phenolic compounds available in gall extracts Unfortunately, it induces the degradation of both ink and support over time. Furthermore, our knowledge of these complex mol. structures is limited. This work aims to overcome this gap, revealing essential information about the complex structures of these pigments and dyes that will create a breakthrough in the next generation of conservation treatments. It presents the first in-depth phenolic identification and quantification of extracts and inks, prepared with and without gum arabic (an essential additive in medieval recipes). Five representative Iberian recipes were selected and prepared Their phenolic profile was analyzed by HPLC-DAD and HPLC-ESI-MS, which revealed that the phenolic compounds present in higher concentration, in the gall extracts, are pentagalloylglucose and hexagalloylglucose (0.15 ± 0.01-32 ± 3 mg/mL), except for one recipe, in which gallic acid is the main phenolic. The influence of the ingredients is also discussed by deconstructing the recipes: extracts of additives as pomegranate peel and solvents used in the extraction of the galls (vinegar and white wine) were characterized.

Scientific Reports published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C3H6O2, Recommanded Product: Methyl 3-phenyl-2-propenoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

D. Desai, Prashil published the artcileSynthesis of ultraviolet curable bisphenol-based epoxy acrylates and comparative study on its physico-chemical properties, Product Details of C15H20O6, the publication is Journal of Applied Polymer Science (2022), 139(17), 52022, database is CAplus.

Photocuring resins have emerged as cutting-edge technol. in coatings, adhesives, composites, additive manufacturing, and so forth. In the present work, different bisphenol, namely A, F, and S, were used to synthesize low mol. weight epoxy resin, which was further reacted with acrylic acid monomer to form bisphenol-based epoxy acrylate (BEA). The BEA resins were formulated using reactive diluents, trimethylolpropane triacrylate, and hexanediol diacrylate in the ratio of 0-40 wt% at the increment of 10 wt% alongside a fixed quantity photoinitiator. These resins were then cast into dumbbell-shaped specimens by irradiating them under UV light. The structural elucidation of BEA resins was performed using Fourier transform IR, NMR, and UV-Vis spectroscopy. The formulated resins were also studied for their rheol. properties. Further, the UV cured specimens were evaluated for mech., thermal, contact angle, and extent of curing. These outcomes were utilized for establishing the structure-property relationship based on the functionality, reactivity, and mol. structure of synthesized BEA resins, which controllers the design architecture and crosslinking d. of UV-cured specimens.

Journal of Applied Polymer Science published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Product Details of C15H20O6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Rauma, Ilkka published the artcileSafety of alemtuzumab in a nationwide cohort of Finnish multiple sclerosis patients, Application of Dimethyl fumarate, the publication is Journal of Neurology (2022), 269(2), 824-835, database is CAplus and MEDLINE.

Alemtuzumab is an effective disease-modifying therapy (DMT) for highly active multiple sclerosis (MS). However, safety concerns limit its use in clin. practice. To evaluate the safety of alemtuzumab in a nationwide cohort of Finnish MS patients. In this retrospective case series study, we analyzed the data of all but two MS patients who had received alemtuzumab in Finland until 2019. Data were systematically collected from patient files. Altogether 121 patients were identified, most of whom had received previous DMTs (82.6%). Median follow-up time after treatment initiation was 30.3 mo and exceeded 24 mo in 78 patients. Infusion-associated reactions (IARs) were observed in 84.3%, 57.3%, and 57.1% of patients during alemtuzumab courses 1-3, resp. Serious adverse events (SAEs) were observed in 32.2% of patients, serious IARs in 12.4% of patients, and SAEs other than IARs in 23.1% of patients. Autoimmune adverse events were observed in 30.6% of patients. One patient died of hemophagocytic lymphohistiocytosis, and one patient died of pneumonia. A previously unreported case of thrombotic thrombocytopenic purpura was documented. SAEs were more frequent in the present cohort than in previous studies. Even though alemtuzumab is a highly effective therapy for MS, vigorous monitoring with a long enough follow-up time is advised.

Journal of Neurology published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C6H8O4, Application of Dimethyl fumarate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Albaneze-Walker, Jennifer published the artcilePractical application of new catalytic methods: a concise synthesis of a potent PDE IV inhibitor, Category: esters-buliding-blocks, the publication is Tetrahedron (2005), 61(26), 6330-6336, database is CAplus.

An efficient synthesis of a potent PDE IV inhibitor I is described. The synthesis is highlighted by two practical and efficient catalytic reactions: a highly selective catalytic palladium mediated carbonylation of the pyridine side chain and an efficient palladium-catalyzed Suzuki-Miyaura coupling of a chloropyridine-N-oxide.

Tetrahedron published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hobdy, Erole published the artcileAN-9 (Titan), Recommanded Product: (Pivaloyloxy)methyl butyrate, the publication is Current Opinion in Investigational Drugs (Thomson Scientific) (2004), 5(6), 628-634, database is CAplus and MEDLINE.

A review. Titan is developing AN-9 for the potential treatment of various cancers. AN-9 is a histone deacetylase inhibitor analog of butyric acid that causes apoptosis of cancer cells through signaling cellular differentiation. In Mar. 2001, a phase I/II study involving patients with liver tumors was initiated. By Nov. 2001, enrollment had been completed in a second phase II study of refractory non-small-cell lung cancer (NSCLC). In June 2003, Titan began enrollment for a phase IIb trial of AN-9 in combination with docetaxel in patients with NSCLC.

Current Opinion in Investigational Drugs (Thomson Scientific) published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Recommanded Product: (Pivaloyloxy)methyl butyrate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Gorshkov, N. I. published the artcileMixed-Ligand Gallium Complexes with N-Vinylpyrrolidone-N-Vinylformamide-N-Vinyliminodiacetic Acid Terpolymers Containing Dithiocarbamates as a Coligand, Formula: C12H17NS2, the publication is Doklady Chemistry (2019), 485(2), 105-108, database is CAplus.

Terpolymers with a mol. weight of 65 and 13 kDa containing 90 mol % of N-vinylpyrrolidone, 7 mol % of N-vinylformamide, and 3 mol % of N-vinyliminodiacetic acid units have been synthesized. Diethyldithiocarbamate and benzyldithiocarbamate have been used as coligands. The mixed-ligand complexation with Ga³⁺ ion has been studied by HPLC. The composition and structure of the resulting metal-polymer complexes have been determined by exclusion chromatog. and spectral (IR, ¹H NMR) data.

Doklady Chemistry published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Formula: C12H17NS2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Rafter, Eoin published the artcileSynthesis of P-stereogenic BINAP bissulfide analogues, Application of (R)-[1,1′-Binaphthalene]-2,2′-diyl bis(trifluoromethanesulfonate), the publication is Tetrahedron: Asymmetry (2011), 22(16-17), 1680-1686, database is CAplus.

BINAP disulfide analogs (1R)-C₂₀H₁₂-2-P(S)Ph₂-2′-P(S)R¹R² (11–15, R¹, R²: Me, Ph; 2-MeOC₆H₄, Ph; 2-MeC₆H₄, Ph; 2-MeOC₆H₄, 2-MeOC₆H₄; 2-MeC₆H₄, 2-MeC₆H₄), containing stereogenic phosphorus center, were prepared by phosphination of 2,2′-BINOL ditriflate with HPPh₂, HPR¹R³ and phosphine oxides with subsequent sulfuration. The synthesis of these ligands was achieved by step-wise palladium and nickel-catalyzed coupling reactions of the precursor binaphthyl triflate with secondary phosphines and phosphine oxides, resp. C₂-Unsym. BINAP bissulfide analogs with the same aryl substituents were also synthesized for the sake of comparison. Preliminary studies of the reduction of these sulfides to the free phosphines are also described.

Tetrahedron: Asymmetry published new progress about 126613-06-7. 126613-06-7 belongs to esters-buliding-blocks, auxiliary class Chiral Diphenols, name is (R)-[1,1′-Binaphthalene]-2,2′-diyl bis(trifluoromethanesulfonate), and the molecular formula is C22H12F6O6S2, Application of (R)-[1,1′-Binaphthalene]-2,2′-diyl bis(trifluoromethanesulfonate).

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics