Esters-buliding-blocks

Busson, P. published the artcilePreparation of Mesogen-Functionalized Dendrimers for Second-Order Nonlinear Optics, Application In Synthesis of 50670-76-3, the publication is Macromolecules (2002), 35(5), 1663-1671, database is CAplus.

Liquid crystalline dendrimers with peripheral mesogen-containing units have been prepared Multistep synthesis with several selective reactions was used in the preparation of the mesogen-containing mols., 4”-[10-(hydroxycarbonyl)decyloxy]phenyl 4-[4′-(2-(R)-octyloxy)-3′-nitrophenyl]benzoate and 4”-[10-(hydroxycarbonyl)decyloxy]biphenyl 4-[4′-(2-(R)-octyloxy)-3′-nitrophenyl]benzoate. Both mols. possessed an electron-accepting nitro group placed perpendicular to the long axis of the mols. in order to enhance the nonlinear optical activity. A second generation hydroxyl functional aliphatic dendrimer based on the dihydroxy acid, 2,2-bis(hydroxymethyl)propionic acid, was used as dendritic scaffold and was subsequently functionalized with the aforementioned groups. The purity and structure of the two liquid crystalline dendrimers were determined by ¹H NMR spectroscopy, size exclusion chromatog., and elemental anal. The synthesis of both the mesogen-containing units and the liquid crystalline dendrimers is described in detail. Investigation of the liquid crystalline properties of the materials by differential scanning calorimetry and optical microscopy showed that they exhibited different mesophases, including the chiral smectic C phase. Ferroelec. switching was observed in this tilted phase, and electrooptical properties, including tilt angle and spontaneous polarization measurements, were investigated. Finally, the nonlinear optical properties of one of the materials were preliminary characterized.

Macromolecules published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Application In Synthesis of 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Stamm, Arne published the artcilePinene-based oxidative synthetic toolbox for scalable polyester synthesis, Computed Properties of 617-52-7, the publication is JACS Au (2021), 1(11), 1949-1960, database is CAplus and MEDLINE.

Generation of renewable polymers is a long-standing goal toward reaching a more sustainable society . Herein we show how conceptually simple oxidative transformations can be used to unlock the inherent reactivity of terpene synthons in generating polyesters by two different mechanisms starting from the same α-pinene substrate. In the first pathway, α-pinene was oxidized into the bicyclic verbanone based lactone (VaL) and subsequently polymerized into star-shaped polymers via ring-opening polymerization, resulting in a biobased semicrystalline polyester with tunable glass transition and melting temperatures In a second pathway, polyesters were synthesized via polycondensation, utilizing the diol (1-(1′-hydroxyethyl)-3-(2′-hydroxyethyl)-2,2-dimethylcyclobutane (HHDC)) synthesized by oxidative cleavage of the double bond of α-pinene, together with unsaturated biobased diesters such as di-Me maleate (DMM) and di-Me itaconate (DMI), resp. The resulting families of terpene-based polyesters were thereafter successfully crosslinked by either transetherification, utilizing the terminal hydroxyl groups of the synthesized verbanone-based materials, or by UV-irradiation, utilizing the unsaturation provided by the DMM or DMI moieties within the HHDC-based copolymers. This work highlights the potential to apply an oxidative toolbox to valorize inert terpene metabolites enabling generation of bio sourced polyesters and coatings thereof by complementary mechanisms.

JACS Au published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C16H14O6, Computed Properties of 617-52-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Katritzky, Alan R. published the artcileNovel Syntheses of 2,3-Dihydro-1,5-benzothiazepin-4(5H)-ones and 2H-1,4-Benzothiazin-3(4H)-ones, SDS of cas: 19788-49-9, the publication is Journal of Organic Chemistry (2001), 66(20), 6792-6796, database is CAplus and MEDLINE.

Nucleophilic additions of α-mercaptoalkanoate esters and β-mercaptoalkanoate acids to benzoquinone diimines, followed by cyclization with trifluoroacetic acid or 1,3-dicyclohexylcarbodiimide (DCC), provide novel, high-yielding syntheses of 2H-1,4-benzothiazin-3(4H)-ones and 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones, resp.

Journal of Organic Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, SDS of cas: 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Thompson, Andrew M. published the artcileRepositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis, Product Details of C9H9NO6S, the publication is Journal of Medicinal Chemistry (2016), 59(6), 2530-2550, database is CAplus and MEDLINE.

6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazole derivatives were initially studied for tuberculosis within a backup program for the clin. trial agent pretomanid (PA-824). Phenotypic screening of representative examples against kinetoplastid diseases unexpectedly led to the identification of DNDI-VL-2098 as a potential first-in-class drug candidate for visceral leishmaniasis (VL). Addnl. work was then conducted to delineate its essential structural features, aiming to improve solubility and safety without compromising activity against VL. While the 4-nitroimidazole portion was specifically required, several modifications to the aryloxy side chain were well-tolerated e.g., exchange of the linking oxygen for nitrogen (or piperazine), biaryl extension, and replacement of Ph rings by pyridine. Several less lipophilic analogs displayed improved aqueous solubility, particularly at low pH, although stability toward liver microsomes was highly variable. Upon evaluation in a mouse model of acute Leishmania donovani infection,phenylpyridine derivative I stood out, providing efficacy surpassing that of the original preclin. lead.

Journal of Medicinal Chemistry published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C7H8O3, Product Details of C9H9NO6S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Akers, R. Patrick published the artcileResponse specificity of male olfactory receptor neurons for the major and minor components of a female pheromone blend, Synthetic Route of 16974-11-1, the publication is Physiological Entomology (1991), 16(1), 1-17, database is CAplus.

The sex attractant of the female redbanded leafroller moth, Argyrotaenia velutinana, is a blend of 7 compounds Specialized olfactory receptor neurons had been found for only 2 of the compounds, (Z)-11-tetradecenyl acetate (Z11-14:Ac) and (E)-11-tetradecenyl acetate (E11-14:Ac). These receptor neurons were always found in pairs within the long trichoid sensilla, which are the most abundant multi-pored sensilla on the male antenna. A systematic survey of all regions of the male antenna with standard extracellular recording techniques was undertaken to find receptor neurons responsive to the remaining 5 minor components of the female pheromone. Of the 113 long trichoid sensilla sampled, all contained 2 receptor neurons, one specialized for Z11-14:Ac and a second specialized for E11-14:Ac. A comparable number of recordings were then obtained from the less abundant classes of multi-pored sensilla. Two new receptor neuron types were found, responsive to the minor pheromone components (E)-9-dodecenyl acetate (E9-12:Ac) and (Z)-9-dodecenyl acetate (Z9-12:Ac). Scanning electron micrographs indicated that these recordings were obtained from shorter, narrower trichoid sensilla. The majority of these sensilla appeared to contain 3 neurons capable of spontaneous action potential production In each sensillum, only one receptor neuron appeared to respond to stimulation with a minor component of the female blend. The remaining 2 neurons did not respond to the chem. stimuli evaluated.

Physiological Entomology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Synthetic Route of 16974-11-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ozturk, Emine published the artcileInvestigation of thermodynamic properties of 4-decyloxybiphenyl-4′-carboxylic acid liquid crystal and preparation of polymer dispersed liquid crystal composite, Application In Synthesis of 50670-76-3, the publication is Journal of Molecular Liquids (2018), 24-30, database is CAplus.

In this study, firstly, retention behavior of solvents on the liquid crystalline material 4-decyloxybiphenyl-4′-carboxylic acid (DBCA) has been studied by inverse gas chromatog. (IGC) technique. Liquid crystal (LC) selectivity was investigated using the acetate isomers by the IGC method at temperatures between 333.2 K and 543.2 K. Later on, the interactions of LC with n-octane, n-nonane, n-decane, undecane, dodecane, tridecane, Pr benzene, iso-Pr benzene, ethylbenzene, chlorobenzene and toluene between 518.2 K and 543.2 K were examined LC-solvent interaction parameters for Flory-Huggins theory, χ^∞₁₂, and equation of state theory, χ^*₁₂, effective exchange energy parameters, X_eff, the weight fraction activity coefficent, Ω^∞₁, the partial molar heat of mixing at infinite dilution of the solvent, ΔH^∞₁, molar heat of vaporization of solvent, ΔH_V and the partial molar heat of sorption of the solvent, ΔH_1,s were obtained. Secondly, polymer dispersed liquid crystal (PDLC) composite film in composition 20/80 poly(Me methacrylate) (PMMA):DBCA by weight was synthesized by solvent-induced phase separation method. The mesomorphic behavior of DBCA and PDLC composite has been investigated by differential scanning calorimetry (DSC) and optical polarizing microscopy (PM).

Journal of Molecular Liquids published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Application In Synthesis of 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ozerol, Esma Ahlatcioglu published the artcileThe impedance and dielectric properties of a chiral biphenylcarboxylic acid liquid crystal, Recommanded Product: Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, the publication is Materials Research Express (2019), 6(6), 065103, database is CAplus.

We have been synthesized a chiral rod-like liquid crystal 4′-(S)-3,7-Dimethyloctyloxy-4-biphenylcarboxylic acid (DMOBC) exhibiting enantiotropic chiral nematic (N*) as a high temperature phase as well as a smectic mesophase (SmI*) in the wide temperature range. The dielec. and impedance properties of 4′-(S)-3,7-Dimethyloctyloxy-4-biphenylcarboxylic acid (DMOBC) liquid crystal have been analyzed over the frequency range from 1 Hz to 10 MHz at the room temperature

Materials Research Express published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Recommanded Product: Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sapozhnikova, Yelena published the artcileScreening of chemicals migrating from plastic food contact materials for oven and microwave applications by liquid and gas chromatography – Orbitrap mass spectrometry, Application of Tris(2,4-di-tert-butylphenyl) phosphite, the publication is Journal of Chromatography A (2021), 462261, database is CAplus and MEDLINE.

Contamination of food with chems. migrating from food contact materials (FCMs) is an important area of food safety. This study was aimed to investigate migration of chems. from plastic FCMs used for microwave and conventional oven heating. Migration tests were conducted for samples of microwave trays, microwave oven bags, and oven bags. GC- and LC-Orbitrap mass spectrometry (MS) was used for non-targeted screening and identification of chems. with mass error <5 ppm. A non-targeted identification approach was validated with isotopically labeled chems. to establish acceptable criteria for identification of migrated compounds A total of 74 migrated compounds were tentatively identified: 24 chems. by GC-Orbitrap MS with electron ionization (EI), plus 35 and 19 by LC-Orbitrap MS electrospray ionization (ESI) with pos. and neg. polarities, resp. Four migrated chems. were identified by more than one instrumental anal. Both intentionally added substances (IAS), i.e. additives used in the production of polymeric materials and plastics, and non-intentionally added substances (NIAS), i.e. derivatives and degradation/oxidation products of IAS, were identified among the migrated chems. The levels of 25 migrated chems. were significantly different (p < 0.05) between microwave treatments and conventional oven treatments, where 20 migrants had higher levels for microwave compared with 5 for conventional oven treatments. For several identified chems., no previous reports on their migration from FCMs were found.

Journal of Chromatography A published new progress about 31570-04-4. 31570-04-4 belongs to esters-buliding-blocks, auxiliary class Mono-phosphine Ligands, name is Tris(2,4-di-tert-butylphenyl) phosphite, and the molecular formula is C42H63O3P, Application of Tris(2,4-di-tert-butylphenyl) phosphite.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Asano, Akiko published the artcileConformational properties of ascydiacyclamide analogs with cyclic α-amino acids instead of oxazoline residues, SDS of cas: 106391-88-2, the publication is Bioorganic & Medicinal Chemistry (2017), 25(24), 6554-6562, database is CAplus and MEDLINE.

Ascidiacyclamide [ASC, cyclo(-Ile-oxazoline-D-Val-thiazole-)₂] is a cyclic octapeptide isolated from tunicates. We designed ASC analogs [cyclo(-Ile-Xxx-D-Val-thiazole-)₂] in which Pro or a homolog was substituted for oxazoline: [Pro]ASC (Xxx: proline), [Aze]ASC (Xxx: (S)-Azetidine-2-carboxylic acid), [Pip]ASC (Xxx: (S)-Piperidine-2-carboxylic acid) and [ΔPro]ASC (Xxx: (S)-3-pyrroline-2-carboxylic acid) to explore their potential to serve as substitutes for the oxazoline ring. The conformations of these analogs were examined using X-ray diffraction, ¹H NMR and CD spectroscopy. In both the crystal and solution states, the conformations of [Pro]ASC, [Aze]ASC and [ΔPro]ASC were novel square structures having two trans imide bonds and stabilized by two intramol. hydrogen bonds. The crystal structure of [Pip]ASC was a folded conformation with cis and trans imide bonds. Three isomers (cc, ct and tt) were present in a solution of [Pip]ASC. From crystal structures, the degree of puckering in the side chains of Pro and its homologues was estimated to be in the order Pip > Pro > Aze > ΔPro. [Pro]ASC and [Pip]ASC showed strong cytotoxicity, but [Aze]ASC and [ΔPro]ASC showed no cytotoxicity. Among the four analogs, there is consistency between the prolyl ring puckering and cytotoxicity, but not between the peptide backbone structure and cytotoxicity.

Bioorganic & Medicinal Chemistry published new progress about 106391-88-2. 106391-88-2 belongs to esters-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Aldehyde, name is (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, and the molecular formula is C10H19NO3, SDS of cas: 106391-88-2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zimra, Yael published the artcileUptake of pivaloyloxymethyl butyrate into leukemic cells and its intracellular esterase-catalyzed hydrolysis, Recommanded Product: (Pivaloyloxy)methyl butyrate, the publication is Journal of Cancer Research and Clinical Oncology (2000), 126(12), 693-698, database is CAplus and MEDLINE.

Pivaloyloxymethyl butyrate (AN-9), a butyric acid (BA) prodrug, exhibited low toxicity and significant anticancer activity in vitro and in vivo. The purpose of this study was to elucidate the basis for AN-9 increased anticancer activity compared to BA, by studying the uptake of BA and AN-9 into the cells. Methods: The uptake rate and level of [¹⁴C]-AN-9 and [¹⁴C]-BA, labeled on the carboxylic moiety of BA, into HL-60 and MEL leukemic cell lines was measured. The cells were filtered and the retained radioactivity was determined The dependence of the uptake on the activity of cellular esterases and membrane fluidity was investigated. Results: The uptake level in cells incubated with [¹⁴C]-AN-9 increased rapidly, peaked after 30 min in MEL and 1 h in HL-60 cells, and declined thereafter. This decline could be attributed to the hydrolysis of AN-9 by cellular esterases and catabolism of the released BA to CO₂. In cells pretreated with an esterase inhibitor and incubated with [¹⁴C]-AN-9, the reduction of radioactivity was less precipitous. In cells exposed to [¹⁴C]-BA, the intracellular radioactivity level was low and unaffected by treatment with an esterase inhibitor. The uptake of [¹⁴C]-AN-9 decreased significantly at 4° compared to that at 37°. Conclusion: The higher potency of AN-9 compared to BA could be at least partially attributed to the more rapid uptake of the lipophilic AN-9 and the release of BA in the cells.

Journal of Cancer Research and Clinical Oncology published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C6H8O6, Recommanded Product: (Pivaloyloxy)methyl butyrate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics