Esters-buliding-blocks

Bamisha, P. published the artcileAn easy access to 2,3-dihydrofuran derivatives by oxidative cyclization reactions, Category: esters-buliding-blocks, the publication is Materials Today: Proceedings (2022), 59(Part_1), 1138-1143, database is CAplus.

An easy and simple access to 2,3-dihydrofuran derivatives from 1,3-dicarbonyl compounds and Me cinnamate was reported. The reaction was facilitated by the CAN mediated oxidative free radical cyclization reaction. Moderate to good yields of products were obtained and preliminary studies of these showed potential medicinal activities. These compounds also find application in material chem. and in dyes.

Materials Today: Proceedings published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sourabie, Alain M. published the artcileIdentification of a Powerful Aroma Compound in Munster and Camembert Cheeses: Ethyl 3-Mercaptopropionate, Synthetic Route of 19788-49-9, the publication is Journal of Agricultural and Food Chemistry (2008), 56(12), 4674-4680, database is CAplus and MEDLINE.

With the view to investigate the presence of thiols in cheese, the use of different methods of preparation and extraction with an organomercuric compound (p-hydroxymercuribenzoate) enabled the isolation of a new compound The anal. of cheese extracts by gas chromatog. coupled with pulse flame photometry, mass spectrometry, and olfactometry detections led to the identification of Et 3-mercaptopropionate in Munster and Camembert cheeses. This compound, described at low concentrations as having pleasant, fruity, grapy, rhubarb, and empyreumatic characters, has previously been reported in wine and Concord grape but was never mentioned before in cheese. A possible route for the formation of this compound in relation with the catabolism of sulfur amino acids is proposed.

Journal of Agricultural and Food Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C10H12O4S, Synthetic Route of 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sourabie, A. M. published the artcileRecent advances in volatile sulfur compounds in cheese: thiols and thioesters, Recommanded Product: Ethyl 2-mercaptopropanoate, the publication is ACS Symposium Series (2011), 119-135, database is CAplus.

A review. Among the numerous compounds involved in cheese aroma, sulfur compounds are of particular interest because of their very powerful odors and low perception thresholds. Nevertheless, little attention has been focused until now on the possible presence of polyfunctional thiols in cheese, even if these compounds have been found to be associated with the flavor of different foods, including fermented ones. The difficulty in isolating volatile thiols in cheeses is probably due to the complexity of this matrix and to the very low concentrations of these compounds that make them undetectable using classic means. Consequently, different methods of sample preparation followed by extractions with p-hydroxymercuribenzoate were used to investigate the possible occurrence of thiol compounds in ripened cheeses. The anal. of cheese extracts by GC coupled with pulse flame photometry, MS and olfactometry detections made it possible to identify Et 2-mercaptopropionate (ET2MP) and Et 3-mercaptopropionate (ET3MP) in smear and mold-ripened cheeses for the first time. The presence of ET3MP in cheeses at concentrations of around 3 μg/kg, significantly higher than its perception threshold in cream (723 ppt), suggests that this thiol may significantly contribute to the aroma of these cheeses. Concerning other potent odors that contribute to the aroma of numerous cheeses, we also investigated the ability of Brevibacteria strains to produce S-Me thioesters in the presence of (i) methanethiol, (ii) fatty acids, or (iii) branched-chain amino acids as precursors. All the strains studied were able to yield the corresponding S-Me thioesters (i.e., S-Me thioisovalerate from L-leucine) from precursors. It was interesting to note that the data also showed that other S-Me thioesters e.g., S-Me thioacetate or S-Me thioisobutyrate, were also produced following the addition of an individual precursor (e.g., L-leucine). Enzymic and tracing experiments allowed us to propose the catabolic pathways used by the strains to produce S-Me thioesters.

ACS Symposium Series published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C8H15ClN2, Recommanded Product: Ethyl 2-mercaptopropanoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Van Lijsebetten, Filip published the artcileReprocessing of Covalent Adaptable Polyamide Networks through Internal Catalysis and Ring-Size Effects, Name: Dimethyl adipate, the publication is Journal of the American Chemical Society (2021), 143(38), 15834-15844, database is CAplus and MEDLINE.

Here, we report the introduction of internally catalyzed amide bonds to obtain covalent adaptable polyamide networks that rely on the dissociation equilibrium between dicarboxamides and imides. While amide bonds are usually considered to be robust and thermally stable, the present study shows that their dynamic character can be activated by a smart choice of available building blocks without the addition of any external catalyst or other additives. Hence, a range of polyamide-based dynamic networks with variable mech. and viscoelastic properties were obtained in a systematic study, using a straightforward curing process of dibasic ester and amine compounds Since the dissociation process involves a cyclic imide formation, the correlation between ring size and the thermomech. viscosity profile was studied for five- to seven-membered ring intermediates, depending on the chosen dibasic ester monomer. This resulted in a marked temperature response with activation energies in the range of 116-197 kJ mol^-1, yielding a sharp transition between elastic and viscous behavior. Moreover, the ease and versatility of this chem. platform were demonstrated by selecting a variety of amines, resulting in densely cross-linked dynamic networks with T_g values ranging from -20 to 110°C. With this approach, it is possible to design amorphous polyamide networks with an acute temperature response, allowing for good reprocessability and, simultaneously, high resistance to irreversible deformation at elevated temperatures

Journal of the American Chemical Society published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C12H13F2N3O4S, Name: Dimethyl adipate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Krause, Andreas published the artcileMatsuda-Heck arylation of itaconates: a versatile approach to heterocycles from a renewable resource, Name: Dimethyl itaconate, the publication is Organic & Biomolecular Chemistry (2021), 19(19), 4292-4302, database is CAplus and MEDLINE.

Itaconic acid esters and hemiesters ROC(O)CH₂C(=CH₂)C(O)OR¹ (R = Me, Et, n-Bu, i-Pr; R¹ = H, Me, Et, n-Bu) undergo Pd-catalyzed coupling reactions with arene diazonium salts ArN₂BF₄ [4-methoxy-2-nitrophenyl, 2-(methoxycarbonyl)thiophen-3-yl, 2-oxo-2H-chromen-6-yl, 2H-1,3-benzodioxol-5-yl, etc.] in high to excellent yields of arylidene succinates (E)-ArCH=C(CH₂C(O)OR)C(O)OR¹. The coupling products of ortho-nitro arene diazonium salts (E)-2-NO₂-R²C₆H₃CH=C(CH₂C(O)OR)C(O)OR¹ (R² = H, 4-Br, 5-Cl, 4-OMe) can be converted in one or two steps to benzazepine-2-ones I (R³ = H, 8-Br, 7-Cl, 8-OMe; R⁴ = methoxycarbonyl, ethoxycarbonyl, hydroxymethyl).

Organic & Biomolecular Chemistry published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, Name: Dimethyl itaconate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dodgson, K. S. published the artcileSulfatases. XV. The arylsulfatases of human serum and urine, Category: esters-buliding-blocks, the publication is Biochemical Journal (1957), 668-73, database is CAplus and MEDLINE.

cf. C.A. 51, 5895e. Human serum and urine exhibit little arylsulfatase (I) activity towards K p-acetylphenyl and p-nitrophenyl sulfates. In certain circumstances urine does show activity towards these substrates, but the activity resides in sedimentable material such as cellular debris and bacteria. Both serum and urine exhibit appreciable I activity towards nitrocatechol sulfate. The activity in urine is a feature of the urine per se and probably arises only in part from cellular debris. Two enzymes, corresponding to I A and I B of human tissues, are responsible for the bulk of the I activity of urine. Some observations on the nonenzymic catalysis by serum of the alk. hydrolysis of p-nitrophenyl sulfate are reported.

Biochemical Journal published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dodgson, K. S. published the artcileSulfatases. IX. The arylsulfatases of mammalian livers, Related Products of esters-buliding-blocks, the publication is Biochemical Journal (1955), 29-37, database is CAplus and MEDLINE.

cf. C.A. 49, 1228a. The presence of 2 arylsulfatases in the livers of rat, ox, rabbit, and mouse has been shown. The enzymes can be distinguished by the ready solubility of one of them (“soluble”) after disruption of the mitochondria by acetone-drying, incubation in hyper- and hypo-tonic solutions, or alternate freezing and thawing. In the rat the “insoluble” enzyme is localized in the microsomes of the liver cell and the soluble enzyme is found mainly in the mitochondria. The insoluble enzyme has a high affinity for p-nitrophenyl and p-acetylphenyl sulfates, while the soluble enzyme has a low affinity for these substrates but a high activity towards nitrocatechol sulfate. The soluble enzyme of rat liver has been further separated into 2 enzymes which are comparable to sulfatases A and B of ox liver.

Biochemical Journal published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dodgson, K. S. published the artcileSulfatase. XI. The purification and properties of the arylsulfatase of Alcaligenes met-alcaligenes, Formula: C6H4KNO6S, the publication is Biochemical Journal (1955), 374-80, database is CAplus and MEDLINE.

cf. C.A. 49, 13305c. The arylsulfatase of A. met-alcaligenes was concentrated and partially separated from nucleic acid and from other enzymes by paper electrophoresis. The enzyme concentrate gave pH-activity and substrate concentration-activity curves which were very similar to those obtained previously with the stage B enzyme (loc. cit.). The ratio of the activities towards the 3 substrates under the resp. optimum conditions was 5.2 p-acetylphenyl (APS), 5.0 p-nitrophenyl (NPS), and 1.0 nitrocatechol (NCS) sulfates, calculated on a molar basis. When account was taken of the inhibition by excess of substrate and the true V_maximum calculated the ratio became 15.1:14.4:1.0. The Michaelis constants, K_m, for the 3 substrates were 9.0, 4.75, and 2.2 × 10^-4M, resp. The heat of activation with NPS was 11 kcal./mol. Inhibition was obtained with the following substances at 0.025M: NaHSO₃ 17%, NaCN 82, NaHSO₃ 34, BaCl₂ 100, glucose 6-sulfate 17, K Et sulfate 12, Na benzenesulfonate 22, phenylhydrazine (0.0001 M) 87, hydrazine 43, semicarbazide 21, thiosemicarbazide 33, dimedone (0.05%, weight/volume) 27, Girards’ reagent P (2.5% weight/volume) 25, NH₂OH 97. Inhibition by p-chloromercuribenzoic acid could not be reversed by cysteine or glutathione. 2,4-Dinitrofluorobenzene at 0.005M gave 100% inhibition. The curves obtained by plotting pK_m against pH have shown the presence in the enzyme of 2 different substrate-binding groups: pK 8.2 and 9.4.

Biochemical Journal published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Formula: C6H4KNO6S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Milovanovic, Dusan published the artcileRisk assessment approach for prioritizing danube basin-specific pollutants: a case study in the novi sad region, Recommanded Product: Isobutyl palmitate, the publication is Polish Journal of Environmental Studies (2019), 28(6), 4297-4309, database is CAplus.

The aim of this work was to determine the most relevant pollutants in Danube surface water and wastewater in the city of Novi Sad, and to conduct a risk assessment approach on substances for the optimization of future monitoring programs. According to the requirements of Serbian law, obligatory and operating monitoring was focused on physico-chem. and biol. parameters while the expanded monitoring programs have not been applied – often due to practical circumstances. Novi Sad, with a population of more than 300.000 inhabitants, does not have a wastewater treatment plant, and about 2 m3 of wastewater is discharged directly to the Danube river every day. Screening analyses of the water within the Danube basin around city of Novi Sad included more than 300 different organic substances, while target anal. was conducted for all WFD pollutants. The methodol. for generating the list of priority substances was applied for the first time in the Danubian region around the city of Novi Sad. By applying the prioritization procedure, 86 organic substances were determined in screening analyses and 27 substances obtained within target analyses were identified as the most relevant. In addition, seasonal variation anal. was conducted to determine the occurrence trends of specific compounds in different seasons.

Polish Journal of Environmental Studies published new progress about 110-34-9. 110-34-9 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester, name is Isobutyl palmitate, and the molecular formula is C20H40O2, Recommanded Product: Isobutyl palmitate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Koch, Bjoern E. V. published the artcileA quantitative in vivo assay for craniofacial developmental toxicity of histone deacetylases, Quality Control of 122110-53-6, the publication is Toxicology Letters (2021), 20-25, database is CAplus and MEDLINE.

Many bony features of the face develop from endochondral ossification of preexisting collagen-rich cartilage structures. The proper development of these cartilage structures is essential to the morphol. formation of the face. The developmental programs governing the formation of the pre-bone facial cartilages are sensitive to chem. compounds that disturb histone acetylation patterns and chromatin structure. We have taken advantage of this fact to develop a quant. morphol. assay of craniofacial developmental toxicity based on the distortion and deterioration of facial cartilage structures in zebrafish larvae upon exposure to increasing concentrations of several well-described histone deacetylase inhibitors. In this assay, we measure the angle formed by the developing ceratohyal bone as a precise, sensitive and quant. proxy for the overall developmental status of facial cartilages. Using the well-established developmental toxicant and histone deacetylase-inhibiting compound valproic acid along with 12 structurally related compounds, we demonstrate the applicability of the ceratohyal angle assay to investigate structure-activity relationships.

Toxicology Letters published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Quality Control of 122110-53-6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics