Esters-buliding-blocks

Coeck, Robin published the artcileOne-pot reductive amination of carboxylic acids: a sustainable method for primary amine synthesis, SDS of cas: 111-11-5, the main research area is carboxylic acid one pot reductive amination primary amine synthesis; ruthenium tungsten bimetallic catalyst green solvent.

The reductive amination of carboxylic acids is a very green, efficient and sustainable method for the production of (bio-based) amines. However, with current technol., this reaction requires two to three reaction steps. Here, we report the first (heterogeneous) catalytic system for the one-pot reductive amination of carboxylic acids to amines, with solely H2 and NH3 as the reactants. This reaction can be performed with relatively cheap ruthenium-tungsten bimetallic catalysts in the green and benign solvent cyclopentyl Me ether (CPME). Selectivities of up to 99% for the primary amine could be achieved at high conversions. Addnl., the catalyst is recyclable and tolerant for common impurities such as water and cations (e.g. sodium carboxylate).

Green Chemistry published new progress about Carboxylic acids Role: RCT (Reactant), RACT (Reactant or Reagent) (C4-C14). 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, SDS of cas: 111-11-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ghate, Tejashree published the artcileThiourea mediated ROS-metabolites reprogramming restores root system architecture under arsenic stress in rice, Formula: C24H14Cl2O7, the main research area is gene expression thiourea arsenic reactive oxygen species root rice; Amino acids; Auxin; Lateral roots; Metabolomics; Redox; Serotonin.

Arsenic (As) is a ubiquitous carcinogenic metalloid that enters into human food chain, through rice consumption. To unravel the conundrum of oxidative vs. reductive stress, the differential root-system architecture (RSA) was studied under As (a ROS producer) and thiourea (TU; a ROS scavenger) alone treatments, which indicated 0.80- and 0.74-fold reduction in the number of lateral roots (NLR), resp. compared with those of control. In case of As+TU treatment, NLR was increased by 4.35-fold compared with those of As-stress, which coincided with partial restoration of redox-status and auxin transport towards the root-tip. The expression levels of 16 ROS related genes, including RBOHC, UPB-1 C, SHR1, PUCHI, were quantified which provided the mol. fingerprint, in accordance with endogenous ROS signature. LC-MS based untargeted and targeted metabolomics data revealed that As-induced oxidative stress was metabolically more challenging than TU alone-induced reductive stress. Cis/trans-ferruloyl putrescine and γ-glutamyl leucine were identified as novel As-responsive metabolites whose levels were decreased and increased, resp. under As+TU than As-treated roots. In addition, the overall amino acid accumulation was increased in As+TU than As-treated roots, indicating the improved nutritional availability. Thus, the study revealed dynamic interplay between ′ROS-metabolites-RSA′, to the broader context of TU-mediated amelioration of As-stress in rice.

Journal of Hazardous Materials published new progress about Auxins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 2044-85-1 belongs to class esters-buliding-blocks, name is 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, and the molecular formula is C24H14Cl2O7, Formula: C24H14Cl2O7.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Quan, Hongping published the artcileThe effect of hydrogen bonds between flow improvers with asphaltene for heavy crude oil, Recommanded Product: Dodecyl 2-methylacrylate, the main research area is asphaltene heavy crude oil hydrogen bond flow improver.

A series of chem. products with characteristic groups in mol. structures were synthesized as novel flow improvers (FIs) for heavy asphaltenic crude oil. The rheol. measurement results showed that the FI-5 could behave the better performance in improving fluidity of heavy oil than FI-2 due to the former could form stronger hydrogen bonds with asphaltene in oil, which was confirmed through Fourier transform IR spectroscopy (FTIR) and energy of simulating studies. Furthermore, X-ray diffraction (XRD) anal. results demonstrated that two products altered asphaltene structure at different degree through hydrogen bonding interaction, and the aggregation-dispersion effect of FIs on asphaltene were resp. obtained through scanning electron microscope (SEM), which beneficially weakened the stable structure of asphaltene in the heavy crude oil system. Hence, the mechanisms were tried to propose that could explain the phenomenon in rheol. measurement why FI-2 was not as good as FI-5 in improving fluidity of heavy oil. Results also indicated that the asphaltene content and aggregation structure in oils were vital parameters for its viscosity.

Fuel published new progress about Aromatic compounds Role: OCU (Occurrence, Unclassified), OCCU (Occurrence). 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Recommanded Product: Dodecyl 2-methylacrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, Yanqin published the artcileAroma dynamic characteristics during the process of variable-temperature final firing of Congou black tea by electronic nose and comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry, COA of Formula: C9H10O2, the main research area is congou black tea faint scent floral aroma; Comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry; Congou black tea; Electronic nose; Final firing; Multivariate statistical analysis.

The drying technol. is crucial to the quality of Congou black tea. In this study, the aroma dynamic characteristics during the variable-temperature final firing of Congou black tea was investigated by electronic nose (e-nose) and comprehensive two-dimensional gas chromatog. coupled to time-of-flight mass spectrometry (GC x GC-TOFMS). Varying drying temperatures and time obtained distinctly different types of aroma characteristics such as faint scent, floral aroma, and sweet fragrance. GC x GC-TOFMS identified a total of 243 volatile compounds Clear discrimination among different variable-temperature final firing samples was achieved by using partial least squares discriminant anal. (R2Y = 0.95, Q2 = 0.727). Based on a dual criterion of variable importance in the projection value (VIP > 1.0) and one-way ANOVA (p < 0.05), ninety-one specific volatile biomarkers were identified, including 2,6-dimethyl-2,6-octadiene and 2,5-diethylpyrazine with VIP > 1.5. In addition, for the overall odor perception, e-nose was able to distinguish the subtle difference during the variable-temperature final firing process.

Food Research International published new progress about Amines Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, COA of Formula: C9H10O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kim, So Young published the artcileROS-mediated anti-tumor effect of Coptidis Rhizoma against human hepatocellular carcinoma Hep3B cells and xenografts, COA of Formula: C24H14Cl2O7, the main research area is reactive oxygen species antitumor Coptidis Rhizoma human hepatocellular carcinoma; Hep3B cell xenograft; Coptidis Rhizoma; Hep3B cells; apoptosis; autophagy; migration.

Coptidis Rhizoma is the dried rhizome from the Coptis chinensis Franch. that has been shown to have a number of beneficial pharmacol. properties including antioxidant, antiinflammatory, and anti-cancer effects. However, the anti-cancer effects of Coptidis Rhizoma on hepatocellular carcinoma (HCC) remain unclear. In this study, we investigated the anti-cancer properties of Coptidis Rhizoma ethanol extract (CR) in HCC Hep3B cells and in a xenograft mouse model. Our results showed that the CR significantly inhibited cell growth and induced apoptosis in Hep3B cells through increased expression of Bcl-2 associated x-protein (Bax) and cleavage of poly-ADP ribose polymerase (PARP), reduced expression of Bcl-2, and activated caspases. CR also increased the generation of intracellular reactive oxygen species (ROS), which caused a loss of mitochondrial membrane potential (MMP, ΔΨm) and activation of the mitochondria-mediated intrinsic apoptosis pathway. Moreover, N-acetylcysteine (NAC), a reactive oxygen species inhibitor, markedly blocked the effects of CR on apoptotic pathways. CR also induced the expression of light chain 3 (LC3)-I/II, a key autophagy regulator, whereas CR-mediated autophagy was significantly suppressed by NAC. In addition, pre-treatment with NAC perfectly attenuated the inhibition of cell invasion and migration of CR-stimulated Hep3B cells. Furthermore, oral administration of CR suppressed Hep3B tumor growth in xenograft mice without toxicity, alterations to body weight, or changes in hematol. and biochem. profiles. Taken together, our findings suggest that CR has anti-tumor effects that result from reactive oxygen species generation, and may be a potential pharmacol. intervention for HCC.

International Journal of Molecular Sciences published new progress about Actins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 2044-85-1 belongs to class esters-buliding-blocks, name is 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, and the molecular formula is C24H14Cl2O7, COA of Formula: C24H14Cl2O7.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Valcarcel-Munoz, Manuel J. published the artcileComparative Evaluation of Brandy de Jerez Aged in American Oak Barrels with Different Times of Use, Application of Ethyl octanoate, the main research area is brandy de Jerez aged American oak barrel different time; Brandy de Jerez; Sherry Cask®; ageing; aroma; oak wood.

Brandy de Jerez is a European Geog. Indication for grape-derived spirits aged in oak casks that have previously contained any kind of Sherry wine and, therefore, are known as Sherry Casks. Wood compounds have a substantial influence in the quality of the brandies that are aged in the barrels. In the cellar, the barrels that have been used for many years to keep Sherry wine or other wine spirits are often used for this purpose. When wooden barrels are used for the first time, they release a large amount of compounds into the liquid contained in them. Such amount decreases over time but casks life cycle has remained unexplored until now. The present work has the aim to study the brandies obtained from the same wine spirit after two years ageing in three differently oak casks: namely new, 7 years of use (4 years containing Oloroso wine and 3 years containing wine spirits) and 32 years of use (8 years containing Oloroso wine and 24 years containing wine spirits). According to the results from our experiments, even after 32 years of use, the wood barrels still contribute to modify the organoleptic characteristics of brandy. Moreover, the brandies aged in used barrels were judged more balanced than those aged in new barrels.

Foods published new progress about Acetals Role: ARU (Analytical Role, Unclassified), ANST (Analytical Study). 106-32-1 belongs to class esters-buliding-blocks, name is Ethyl octanoate, and the molecular formula is C10H20O2, Application of Ethyl octanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ianni, Andrea published the artcileEffects of selenium supplementation on chemical composition and aromatic profiles of cow milk and its derived cheese, Recommanded Product: Ethyl nonanoate, the main research area is selenium supplementation chem composition aromatic profile milk cheese; fatty acid; oxidative stability; selenium; volatile compound.

This study aimed to investigate the effect of dietary selenium supplementation of Friesian cows on chem.-nutritional and volatile fraction of caciocavallo cheese. A sample of 32 Friesian cows, balanced for parity, milk production, and days in milk, were randomly assigned to 2 groups. The control group (CG) was fed with a conventional feeding strategy, while the exptl. group (SeG) received a daily selenomethionine supplementation of 0.45 mg/kg in total mixed ration. During the exptl. period, milk yield was monitored, and samples of milk and caciocavallo cheese were collected and analyzed to obtain information on chem.-nutritional composition and volatile compounds profile. Dietary Se integration did not induce variations on milk yield or composition but significantly lowered the somatic cell count (SCC). In both milk and cheese, samples from SeG were characterized by a lower concentration of saturated fatty acids (SFA) and increases in linoleic and rumenic acids. The volatile compounds profile of dairy products was also pos. affected by dietary Se intake, with an increase in concentration of free fatty acids, esters, and aldehydes. These results suggest that Se plays a pos. role in improving bovine mammary gland functionality and the nutraceutical properties of milk and caciocavallo cheese made therefrom. Such findings could contribute to the production of cheeses with interesting organoleptic properties, although further sensorial evaluations should be performed to deeply investigate these changes and confirm consumer acceptability.

Journal of Dairy Science published new progress about Caseins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 123-29-5 belongs to class esters-buliding-blocks, name is Ethyl nonanoate, and the molecular formula is C11H22O2, Recommanded Product: Ethyl nonanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ianni, Andrea published the artcileEffects of selenium supplementation on chemical composition and aromatic profiles of cow milk and its derived cheese, Safety of Methyl octanoate, the main research area is selenium supplementation chem composition aromatic profile milk cheese; fatty acid; oxidative stability; selenium; volatile compound.

This study aimed to investigate the effect of dietary selenium supplementation of Friesian cows on chem.-nutritional and volatile fraction of caciocavallo cheese. A sample of 32 Friesian cows, balanced for parity, milk production, and days in milk, were randomly assigned to 2 groups. The control group (CG) was fed with a conventional feeding strategy, while the exptl. group (SeG) received a daily selenomethionine supplementation of 0.45 mg/kg in total mixed ration. During the exptl. period, milk yield was monitored, and samples of milk and caciocavallo cheese were collected and analyzed to obtain information on chem.-nutritional composition and volatile compounds profile. Dietary Se integration did not induce variations on milk yield or composition but significantly lowered the somatic cell count (SCC). In both milk and cheese, samples from SeG were characterized by a lower concentration of saturated fatty acids (SFA) and increases in linoleic and rumenic acids. The volatile compounds profile of dairy products was also pos. affected by dietary Se intake, with an increase in concentration of free fatty acids, esters, and aldehydes. These results suggest that Se plays a pos. role in improving bovine mammary gland functionality and the nutraceutical properties of milk and caciocavallo cheese made therefrom. Such findings could contribute to the production of cheeses with interesting organoleptic properties, although further sensorial evaluations should be performed to deeply investigate these changes and confirm consumer acceptability.

Journal of Dairy Science published new progress about Caseins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Safety of Methyl octanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Conte, Pellegrino published the artcileFast field cycling NMR relaxometry as a tool to monitor Parmigiano Reggiano cheese ripening, Recommanded Product: Methyl octanoate, the main research area is Parmigiano Reggiano cheese ripening NMR relaxometry; Ageing; Fast field cycling NMR relaxometry; Fatty acids; Maturation index; Parmigiano Reggiano cheese; Volatile compounds; Water activity.

It is widely recognized that the longer the ageing, the more valuable Parmigiano Reggiano (PR) cheese becomes, due to the improvement of its sensorial and nutritional properties. Up to now, the evaluation of PR properties has been performed on samples mainly aged up to 40 mo. For this reason, this study was aimed at collecting information about the chem.-phys. characteristics of PR cheeses after ageing at 24, 48 and 84 mo. The basic analyses on water amount, protein content and volatile organic compounds (VOC) revealed that PR ageing is associated to the decomposition of the organic components into smaller units. This drives water mols. closer to the aforementioned units, thereby leading to a reduction of water activity. Moreover, it appears, from VOC investigation, that either the total amount of long chain fatty acids (LCFA) or the sole 9Z-octadecenoic acid considerably increased with PR aging, thereby making these mol. systems good fingerprint to monitor PR ripening. Fast field cycling (FFC) NMR relaxometry revealed different components of the mol. dynamics in the complex PR cheese samples, which were attributed to water trapped in casein micelles, water bound to polar groups in organic components, proteins, and fats. In particular, the reduction of the correlation times associated to the organic components was explained by the mol. size decrement following degradation processes. The ageing-independent component of the motion was assigned to water mols. bound to polar groups in organic moieties. Finally, the ageing-independent contribution to the overall relaxation rate was assigned to water mols. in casein micelles. This study revealed that FFC NMR relaxometry can be a promising technique to monitor the chem. phys. changes during Parmigiano Reggiano cheese ripening.

Food Research International published new progress about Caseins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Recommanded Product: Methyl octanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pavlovic, Radmila published the artcileEffectiveness of different analytical methods for the characterization of propolis: a case of study in Northern Italy, HPLC of Formula: 140-11-4, the main research area is propolis phenol flavone radical scavenger HPLC GC MS; HPLC–Q-Exactive-Orbitrap®–MS analysis; phenolic glycerides; poplar; propolis.

Propolis is used as folk medicine due to its spectrum of alleged biol. and pharmaceutical properties and it is a complex matrix not still totally characterized. Two batches of propolis coming from two different environments (plains of Po Valley and the hilly Ligurian-Piedmont Apennines) of Northern Italy were characterized using different anal. methods: Spectrophotometric anal. of phenols, flavones and flavonols, and DPPH radical scavenging activity, HPLC, NMR, HSPME and GC-MS and HPLC-MS Orbitrap. Balsam and moisture content were also considered. No statistical differences were found at the spectrophotometric anal.; balsam content did not vary significantly. The most interesting findings were in the VOCs composition, with the Po Valley samples containing compounds of the resins from leaf buds of Populus nigra L. The hills (Appennines) samples were indeed characterize by the presence of phenolic glycerides already found in mountain environments. HPLC-Q-Exactive-Orbitrap-MS anal. is crucial in appropriate recognition of evaluate number of metabolites, but also NMR itself could give more detailed information especially when isomeric compounds should be identified. It is necessary a standardized evaluation to protect and valorize this production and more research on propolis characterization using different anal. techniques.

Molecules published new progress about Balsams Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, HPLC of Formula: 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics