Esters-buliding-blocks

Yasukouchi, Hiroaki published the artcileEfficient and Practical Deacylation Reaction System in a Continuous Packed-Bed Reactor, Recommanded Product: Benzyl acetate, the main research area is alc preparation; chemoselective deacylation ester packed bed reactor ion exchange resin; ion exchange resin catalyst deacylation ester packed bed reactor.

Esters such as benzyl acetate underwent deacylation using a packed-bed reactor containing the ion-exchange resins DIAION 306 and DIAION PA 308 (after anion exchange with sodium hydroxide or methoxide) in flow to yield alcs.; the flow process offers improved isolability and yields over the comparable batch process. The deacylation reaction was used for hydrolysis of intermediates towards efinaconazole and atorvastatin.

Organic Process Research & Development published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Recommanded Product: Benzyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sousa, Sara C. A. published the artcileBench-Stable Manganese NHC Complexes for the Selective Reduction of Esters to Alcohols with Silanes, HPLC of Formula: 111-11-5, the main research area is alc preparation chemoselective; ester reduction manganese catalyst.

Selective reduction of esters to alcs. RCH2OH [R = cyclohexyl, Ph, 4-ClC6H4, etc.] was accomplished through Mn(I)-mediated hydrosilylation reaction. The manganese tricarbonyl complex [Mn(bis-NHC)(CO)3Br] resulted an active pre-catalyst for the reduction of a variety of esters using phenylsilane and the cheap and readily available polymethylhydrosiloxane.

Advanced Synthesis & Catalysis published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, HPLC of Formula: 111-11-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, Xintuo published the artcilePalladium(II)-Catalyzed Enantioselective Hydrooxygenation of Unactivated Terminal Alkenes, Application In Synthesis of 583-04-0, the main research area is terminal alkene carboxylic acid palladium catalyst enantioselective hydrooxygenation; ester preparation.

A novel Pd(II)-catalyzed enantioselective Markovnikov hydrooxygenation of unactivated terminal alkenes using a substituted pyridinyl oxazoline (Pyox) ligand was developed. Herein it was discovered that the (EtO)2MeSiH/BQ redox system is vital for the highly selective and efficient hydrooxygenation, where the alkylpalladium(II) species generated from enantioselective oxypalladation step was reduced by silane. This method provides efficient access to optically pure alc. esters from easily available alkenes with excellent enantioselectivities and features a broad substrate scope.

Journal of the American Chemical Society published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Application In Synthesis of 583-04-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Xiaomin published the artcileA novel hafnium-graphite oxide catalyst for the Meerwein-Ponndorf-Verley reaction and the activation effect of the solvent, Application In Synthesis of 539-88-8, the main research area is hafnium graphite oxide catalyst preparation; alc preparation; carbonyl compound Meerwein Ponndorf Verley hydrogenation hafnium graphite oxide.

A novel, efficient, and easily prepared hafnium-graphite oxide (Hf-GO) catalyst was constructed via the coordination between Hf4+ and the carboxylic groups in GO. Prepared catalyst was aplied for synthesis of alcs., e.g., I via hydrogenation of biomass derived carbonyl compounds using Meerwein-Ponndorf-Verley (MPV) reaction. The catalyst gave high efficiency under mild conditions. An interesting phenomenon was found whereby the activity of the catalyst increased gradually in the initial stage during reaction. The solvent, isopropanol, was proved to have an activation effect on the catalyst, and the activation effect varied with different alcs. and temperatures Further characterizations showed that isopropanol played the activation effect via replacing the residual solvent (DMF) in micro- and mesopores during the preparation process, which was hard to be completely removed by common drying process.

RSC Advances published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Application In Synthesis of 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Yuxin published the artcileDirect use of the solid waste from oxytetracycline fermentation broth to construct Hf-containing catalysts for Meerwein-Ponndorf-Verley reactions, Safety of Ethyl 4-oxopentanoate, the main research area is hafnium based oxytetracycline fermentation broth residue catalyst preparation; alc green preparation; biomass derived carbonyl compound hafnium catalyst Meerwein Ponndorf Verley.

In this study, a novel route of using oxytetracycline fermentation broth residue (OFR) was proposed that OFR was used as the organic ligands to construct a new hafnium based catalyst (Hf-OFR) for Meerwein-Ponndorf-Verley (MPV) reactions of biomass-derived platforms. The acidic groups in OFR were used to coordinate with Hf4+, and the carbon skeleton structures in OFR were used to form the spatial network structures of the Hf-OFR catalyst. The results showed that the synthesized Hf-OFR catalyst could catalyze the MPV reduction of various carbonyl compounds under relatively mild reaction conditions, with high conversions and yields. Besides, the Hf-OFR catalyst could be recycled at least 5 times with excellent stability in activity and structures. The prepared Hf-OFR catalyst possesses the advantages of high efficiency, a simple preparation process, and low cost in ligands. The proposed strategy of constructing catalysts using OFR might be provide new routes for both valuable utilization of the OFR solid waste in the fermentation industry and the construction of efficient catalysts for biomass conversion.

RSC Advances published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Safety of Ethyl 4-oxopentanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chiu, Ting-Yu published the artcileA Dinuclear Dysprosium Complex as an Air-Stable and Recyclable Catalyst: Applications in the Deacetylation of Carbohydrate, Aliphatic, and Aromatic Molecules, Recommanded Product: Benzyl acetate, the main research area is dinuclear dysprosium complex catalyst green preparation; alc green preparation chemoselective; ester deacetylation dinuclear dysprosium catalyst; carbohydrates; deacetylation; dysprosium; homogeneous catalysis.

Three dinuclear dysprosium complexes, [Dy2(hmb)2(OTf)2(H2O)4].HOTf.2THF (A.HOTf.2THF), [Dy2(hmb)2(OTf)2(H2O)4].(CH3)2CO (A.(CH3)2CO) and [Dy2(hmi)3(H2O)2].2HOTf (B.2HOTf), were synthesized by the reaction of Dy(OTf)3 and the Schiff-base ligands H2hmb (N’-(2-hydroxy-3-methoxybenzylidene)benzohydrazide) or H2hmi ((2-hydroxy-3-methoxyphenyl)methylene isonicotinohydrazine). Complex A.HOTf.2THF was an effective and chemoselective catalyst for the deacetylation of esters in methanol. This method offered an efficient route to selectively deacetylated monosaccharides and disaccharides in high yields and a green catalyst that can be easily recycled and reused. This method was especially valuable for the preparation of peracetylated hemiacetal of monosaccharides and disaccharides with yields of 85 to 88 and 65 to 85%, resp. Complex (B.2HOTf), in comparison, indicated that coordinated triflate ions were key to activation of the regioselective anomeric deacetylation.

Chemistry – An Asian Journal published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Recommanded Product: Benzyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Leng, Yan published the artcileA tannin-derived zirconium-containing porous hybrid for efficient Meerwein-Ponndorf-Verley reduction under mild conditions, Related Products of esters-buliding-blocks, the main research area is reusable zirconium tannin complex catalyst preparation property; carbonyl compound zirconium Meerwein Ponndorf Verley reduction green chem; alc preparation.

Tannins were simply assembled with zirconium in water for the scalable preparation of a heterogeneous zirconium-tannin hybrid catalyst (Zr-tannin) was studied. Various characterizations demonstrated the formation of robust porous inorganic-organic frameworks and strong Lewis acid-base sites in Zr-tannin. The cooperative effect of these acid-base sites and the abundant porosity endowed Zr-tannin with a remarkable catalytic performance for the MPV reduction of a broad range of carbonyl compounds to alcs. with 2-propanol under mild conditions. Moreover, Zr-tannin exhibited good recyclability for at least five reaction cycles. This novel strategy using tannins as the raw materials to construct heterogeneous catalytic materials may have a huge potential for green chem. synthesis due to low cost, nontoxicity, and sustainability.

Green Chemistry published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yao, Zi-Jian published the artcileCatalytic hydrogenation of carbonyl and nitro compounds using an [N,O]-chelate half-sandwich ruthenium catalyst, Application In Synthesis of 5405-41-4, the main research area is ruthenium sandwich catalyst preparation crystal structure; nitro compound ruthenium sandwich catalyst hydrogenation; carbonyl compound ruthenium sandwich catalyst hydrogenation.

A series of N,O-chelate half-sandwich ruthenium complexes for both carbonyl and nitro compound hydrogenation have been synthesized based on β-ketoamino ligands. All complexes exhibited high activity for the catalytic hydrogenation of a series of ketones and nitroarenes with mol. H2 as the reducing reagent in aqueous medium. Consequently, the catalytic system showed the catalytic TON values of 950 for 1-phenylethanol in acetophenone hydrogenation and 1960 for 1-chloro-4-nitrobenzene in p-chloroaniline hydrogenation. Good catalytic activity was displayed for various kinds of substrates with either electron-donating or electron-withdrawing groups. The neutral ruthenium complexes 1-4 were fully characterized using NMR, IR, and elemental anal. Mol. structures of complexes 2 and 4 were further confirmed using single-crystal X-ray diffraction anal.

Dalton Transactions published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 5405-41-4 belongs to class esters-buliding-blocks, name is Ethyl 3-hydroxybutanoate, and the molecular formula is C6H12O3, Application In Synthesis of 5405-41-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Feng, Xuanyu published the artcileAluminum Hydroxide Secondary Building Units in a Metal-Organic Framework Support Earth-Abundant Metal Catalysts for Broad-Scope Organic Transformations, Application In Synthesis of 140-11-4, the main research area is metal organic framework catalyst organic transformation.

The intrinsic heterogeneity of alumina (Al2O3) surface presents a challenge for the development of alumina-supported single-site heterogeneous catalysts and hinders the characterization of catalytic species at the mol. level as well as the elucidation of mechanistic details of the catalytic reactions. Here we report the use of aluminum hydroxide secondary building units (SBUs) in the MIL-53(Al) metal-organic framework (MOF) with the formula Al(μ2-OH)(BDC) (BDC = 1,4-benzenedicarboxylate) as a uniform and structurally defined functional mimic of Al2O3 surface for supporting Earth-abundant metal (EAM) catalysts. The μ2-OH groups in MIL-53(Al) SBUs were readily deprotonated and metalated with CoCl2 and FeCl2 to afford MIL-53(Al)-CoCl and MIL-53(Al)-FeCl precatalysts which were characterized by powder X-ray diffraction, nitrogen sorption, elemental anal., d. functional theory, and extended X-ray fine structure spectroscopy. Activation with NaBEt3H converted MIL-53(Al)-CoCl to MIL-53(Al)-CoH which effectively catalyzed hydroboration of alkynes and nitriles and hydrosilylation of esters. XPS and X-ray absorption near-edge spectroscopy (XANES) indicated the presence of AlIII and CoII centers in MIL-53(Al)-CoH while deuterium labeling studies suggested σ-bond metathesis as a key step for the MIL-53(Al)-CoH-catalyzed addition reactions. MIL-53(Al)-FeCl competently catalyzed oxidative Csp3-H amination and Wacker-type alkene oxidation XANES anal. revealed the oxidation of FeII to FeIII centers in the activated MIL-53(Al)-FeCl catalyst and suggested that oxidative Csp3-H amination occurs via the formation of FeIII-OtBu species by single electron transfer between FeII centers in MIL-53(Al)-FeCl and (tBuO)2 with concomitant generation of 1 equiv of tBuO· radical, C-H activation through hydrogen atom abstraction to generate alkyl radicals, protonation of FeIII-OtBu by aniline to generate MIL-53(Al)-FeIII-anilide, and finally C-N coupling between the FeIII-anilide and alkyl radical to form the Csp3-H amination product and regenerate the FeII catalyst. These highly active single-site MOF-based solid catalysts were readily recovered and reused up to five times without significant decrease in catalytic activity. This work thus demonstrates the great potential of using the aluminum hydroxide SBUs in MOFs to support EAM catalysts for important organic transformations.

ACS Catalysis published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Application In Synthesis of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Feng, Xuanyu published the artcileAluminum Hydroxide Secondary Building Units in a Metal-Organic Framework Support Earth-Abundant Metal Catalysts for Broad-Scope Organic Transformations, Application In Synthesis of 111-11-5, the main research area is metal organic framework catalyst organic transformation.

The intrinsic heterogeneity of alumina (Al2O3) surface presents a challenge for the development of alumina-supported single-site heterogeneous catalysts and hinders the characterization of catalytic species at the mol. level as well as the elucidation of mechanistic details of the catalytic reactions. Here we report the use of aluminum hydroxide secondary building units (SBUs) in the MIL-53(Al) metal-organic framework (MOF) with the formula Al(μ2-OH)(BDC) (BDC = 1,4-benzenedicarboxylate) as a uniform and structurally defined functional mimic of Al2O3 surface for supporting Earth-abundant metal (EAM) catalysts. The μ2-OH groups in MIL-53(Al) SBUs were readily deprotonated and metalated with CoCl2 and FeCl2 to afford MIL-53(Al)-CoCl and MIL-53(Al)-FeCl precatalysts which were characterized by powder X-ray diffraction, nitrogen sorption, elemental anal., d. functional theory, and extended X-ray fine structure spectroscopy. Activation with NaBEt3H converted MIL-53(Al)-CoCl to MIL-53(Al)-CoH which effectively catalyzed hydroboration of alkynes and nitriles and hydrosilylation of esters. XPS and X-ray absorption near-edge spectroscopy (XANES) indicated the presence of AlIII and CoII centers in MIL-53(Al)-CoH while deuterium labeling studies suggested σ-bond metathesis as a key step for the MIL-53(Al)-CoH-catalyzed addition reactions. MIL-53(Al)-FeCl competently catalyzed oxidative Csp3-H amination and Wacker-type alkene oxidation XANES anal. revealed the oxidation of FeII to FeIII centers in the activated MIL-53(Al)-FeCl catalyst and suggested that oxidative Csp3-H amination occurs via the formation of FeIII-OtBu species by single electron transfer between FeII centers in MIL-53(Al)-FeCl and (tBuO)2 with concomitant generation of 1 equiv of tBuO· radical, C-H activation through hydrogen atom abstraction to generate alkyl radicals, protonation of FeIII-OtBu by aniline to generate MIL-53(Al)-FeIII-anilide, and finally C-N coupling between the FeIII-anilide and alkyl radical to form the Csp3-H amination product and regenerate the FeII catalyst. These highly active single-site MOF-based solid catalysts were readily recovered and reused up to five times without significant decrease in catalytic activity. This work thus demonstrates the great potential of using the aluminum hydroxide SBUs in MOFs to support EAM catalysts for important organic transformations.

ACS Catalysis published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Application In Synthesis of 111-11-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics