Esters-buliding-blocks

Radulovic, Niko S. published the artcileImmunomodulatory Constituents of Conocephalum conicum (Snake Liverwort) and the Relationship of Isolepidozenes to Germacranes and Humulanes, Recommanded Product: Ethyl pentadecanoate, the main research area is immunomodulatory Conocephalum isolepidozene germacrane humulane.

Structural elucidation of three new sesquiterpenoids, namely, (1Z,4E)-lepidoza-1(10),4-dien-14-ol (I), rel-(1(10)Z,4S,5E,7R)-germacra-1(10),6 diene-11,14-diol (2), and rel-(1(10)Z,4S,5E,7R)-humula-1(10),5-diene-7,14-diol (3), isolated from the liverwort Conocephalum conicum, was accomplished by a combination of extensive NMR experiments, 1H NMR simulation, and other means. Addnl., the change of the identity of bicyclogermacren-14-al, previously reported as a C. conicum constituent, to isolepidozen-14-al is proposed. Compounds 2 and 3 appear to be related to I via hydration involving a shared intermediate, a substituted cyclopropylmethyl cation, formed by a highly regio- and stereoselective protonation of I, followed by a stereospecific fission of the three-membered ring. In other words, an isolepidozene derivative might be a branchpoint to humulanes and germacranes; this transformation could be of, up to now, unknown, biosynthetic and/or synthetic relevance. Multivariate statistical anal. of the compositional data of C. conicum extract constituents was used to probe the hypothesized biochem. relations. The immunomodulatory effect of I-3 and conocephalenol (4) was evaluated in an in vitro model on both nonstimulated and mitogen-stimulated rat splenocytes. The compounds displayed varying degrees of cytotoxicity to nonstimulated splenocytes, whereas 2 and 3 were found to exert immunosuppressive effects on Con A-stimulated splenocytes while not being cytotoxic at the same concentrations

Journal of Natural Products published new progress about Conocephalum conicum. 41114-00-5 belongs to class esters-buliding-blocks, name is Ethyl pentadecanoate, and the molecular formula is C17H34O2, Recommanded Product: Ethyl pentadecanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Youqiang published the artcileA highly sensitive strain sensor based on a silica@polyaniline core-shell particle reinforced hydrogel with excellent flexibility, stretchability, toughness and conductivity, Category: esters-buliding-blocks, the main research area is polyaniline silica core shell particle reinforced hydrogel strain sensor.

Hydrogel-based flexible strain sensors for personal health monitoring and human-machine interaction have attracted wide interest among researchers. In this paper, hydrophobic association and nanocomposite conductive hydrogels were successfully prepared by introducing polyaniline coated silica (SiO2@PANI) core-shell particles into an acrylamide-lauryl methacrylate (P(AM/LMA)) copolymer matrix. The hydrophobic interaction between the SiO2@PANI core-shell particles and the hydrophobic LMA in the P(AM/LMA) chains induced the hydrogels with outstanding mech. properties. Furthermore, the polyaniline on the SiO2 surface and the inorganic salt formed a conductive network, which synergistically enhanced the conductivity of the hydrogels. The obtained hydrogels integrate high tensile strength (1398 kPa), ultra-stretchability (>1000%), wonderful strain sensitivity (gauge factor = 10.407 at 100-1100% strain), quick response (300 ms), and excellent durability (>300 cycles) due to the hydrophobic association and nanocomposite effect. The prepared SiO2@PANI-P(AM/LMA) hydrogel shows high stress sensitivity to detect human movements and displays a broad application prospect in flexible strain-sensor field.

Soft Matter published new progress about Compressive strength. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhao, Zhen published the artcileTough and self-healing hydrophobic association hydrogels with cationic surfactant, Application In Synthesis of 142-90-5, the main research area is acrylamide lauryl methacrylate copolymer hydrogel micellar copolymerization hydrophobic association; mech rheol self healing property.

Hydrophobic association (HA) hydrogels with outstanding mech., rheol. and recovery properties were successfully synthesized by micellar copolymerization of acrylamide with lauryl methacrylate. The synthesis occurred at room temperature and the synthesis condition was moderate by using the redox initiator system of ammonium persulfate – sodium bisulfite as initiators. Cationic surfactant (dodecyl tri-Me ammonium bromide) was utilized to form micelles with hydrophobe, served as phys. crosslinking points in the 3D networks of hydrogels. The HA hydrogels showed a high tensile strength of 181 kPa, superior stretchability of 2300% and excellent toughness of 2.16 MJ m-3. Moreover, they owned extraordinary self-recovery under different conditions. It is hopeful that the hydrogels with superior mech. strength and self-healing properties would be applied to the fields of biomedicine and engineering. Meanwhile, based on above materials, HA hydrogels could also be synthesized with the combination of hydrophobic association and other synergistic effects, such as latex particles, electrostatic effect and nanoparticles.

Journal of Applied Polymer Science published new progress about Cationic surfactants. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Application In Synthesis of 142-90-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Marques Cardoso, Carlos Magno published the artcileTransesterification of Pequi (Caryocar brasiliensis Camb.) bio-oil via heterogeneous acid catalysis: Catalyst preparation, process optimization and kinetics, Application of Methyl docosanoate, the main research area is Caryocar bio oil FAME heterogeneous acid catalysis.

The transesterification of Pequi (Caryocar brasiliensis Camb.) bio-oil was conduct with a heterogeneous acid catalyst prepared with the fruit’s carbonized rinds. The newly-developed catalyst was characterized by TGA/DSC, XRD diffraction, and FTIR anal. Experiments for process optimization of biodiesel production and catalyst reusability were carried out, also investigating the kinetics involved in bio-oil mass conversion. Crude FAME content was analyzed with GC-FID gas chromatographer and its fuel properties compared to worldwide standards Main finds were a crude FAME majorly composed by Me esters of palmitic acid, linoleic acid, and stearic acid, representing about 49.93, 13.24, and 10.16 weight%, resp. Optimized conditions for maximum FAME synthesis from Pequi bio-oil (99.4 ± 0.33%) were 18:1 M ratio of methanol to bio-oil, 60°C of temperature, 100 min of reaction, catalyst load of 2.5 weight%, and stirring speed of 600 rpm. Kinetics of the bio-oil mass conversion through transesterification presented reaction rates varying from 0.016 to 0.091 min-1, 63.07 kJ kg-1 of activation energy (Ea), and pre-exponential value (A) of 11.4E105. Catalyst efficiency decreased to 34.9% after 10 reuse cycles. Fuel properties of the crude FAME met worldwide standards of biodiesel quality, thus indicate that Pequi bio-oil is a viable, sustainable, and widely available feedstock option in Brazil.

Industrial Crops and Products published new progress about Caryocar brasiliense. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, Application of Methyl docosanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Cheng published the artcileAsymmetric reduction of 2-chloro-3-oxo-ester into enantiomerically high pure diltiazem precursor by a Candida ketoreductase, Application In Synthesis of 5405-41-4, the main research area is Candida ketoreductase asym reduction oxoester chiral synthon diltiazem.

Me (2R,3S)-3-(4-methoxyphenyl)glycidate [(2R,3S)-MPGM] is an advanced chiral synthon for the synthesis of the cardiovascular drug diltiazem. It can be easily accessed by cyclizing the reduction products of Me 2-chloro-3-(4-methoxyphenyl)-3-oxo-propanoate. Herein, we report an identified carbonyl reductase (CpKR) from Candida parapsilosis that displayed an excellent stereoselectivity toward the keto substituent at the C3-position of the 2-chloro-3-oxo-ester. The engineered Escherichia coli cells harboring CpKR gene were directly applied for the asym. reduction of keto ester 1a with a space-time yield of 46 g L-1 d-1, which represents the highest productivity in bio-reduction reported so far. The isolated chiral alc. products were then applied to the chem. synthesis of (2R,3S)-MPGM in 99% ee and a total yield of 76% in the two-step chemo-enzymic reactions, which far exceeded the maximum theor. yield (50%) of the existing industrial process based on a lipase-catalyzed resolution of racemic MPGM. This work provides a promising eco-friendly and cost-effective route toward industrial synthesis of pharmaceutically relevant diltiazem.

Molecular Catalysis published new progress about Candida parapsilosis. 5405-41-4 belongs to class esters-buliding-blocks, name is Ethyl 3-hydroxybutanoate, and the molecular formula is C6H12O3, Application In Synthesis of 5405-41-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Junshuai published the artcileMeasurement of the Speed of Sound in Methyl Caprylate from 298.22 to 608.38 K and up to 10 MPa, Synthetic Route of 111-11-5, the main research area is sound velocity methyl caprylate Brillouin light scattering.

Me caprylate is expected to be one of the main components of biodiesel due to its high cetane number and good oxidation stability. Details of the exptl. speeds of sound in Me caprylate are very scarce, especially in high-temperature regions. Therefore, the speed of sound in liquid Me caprylate was measured by the Brillouin light scattering method in the temperature range of 298.22-608.38 K and at pressures of up to 10 MPa. The relative expanded uncertainty of the speed of sound is estimated to be less than 1.32% (coverage factor k = 2). The variation of the speed of sound with the temperature and pressure was analyzed. Besides, the correlation for the speed of sound as a function of temperature and pressure is presented based on the exptl. data. The absolute average of relative deviation between the exptl. data and the calculated results is 0.29%.

Journal of Chemical & Engineering Data published new progress about Brillouin scattering. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Synthetic Route of 111-11-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tusskorn, Ornanong published the artcileBorassus flabellifer L. crude male flower extracts alleviate cisplatin-induced oxidative stress in rat kidney cells, Application of 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, the main research area is Borassus flabellifer cisplatin oxidative stress kidney cell.

To investigate the effects of Borassus flabellifer L. extracts on antioxidant activity, maintenance of cellular redox, and mitochondrial function in cisplatin-induced kidney injury. The extracts of Borassus flabellifer were obtained from crude male flowers using Et acetate and methanol. The antioxidant potential was evaluated by 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid), 2,2-diphenyl-1-picrylhydrazyl, and ferric reducing antioxidant power, and total phenolic content was also determined Cytoprotective activity of Et acetate and methanolic extracts was assessed after kidney cells were treated with cisplatin. Oxidative stress was determined by glutathione (GSH) assay, and formation of reactive oxygen species (ROS) and changes in mitochondrial transmembrane potential (ΔΨm) using 2″”,7″”-dichlorofluorescin diacetate and JC-10 assays, resp. Borassus flabellifer methanolic extract exhibited greater antioxidant activity than the Et acetate extract Cytoprotective effect was demonstrated in both extracts, particularly in the Et acetate extract The extracts showed protection against the cytotoxic effect of cisplatin by prevention of the increased GSSG and declined GSH/GSSG ratio. Both extracts also prevented the increase in ROS formation, and loss of ΔΨm. Both Borassus flabellifer extracts show antioxidant activity and cytoprotective effect against cisplatin-induced cytotoxicity of NRK-52E cells by preventing oxidative stress and maintenance of GSH redox status. Borassus flabellifer extracts may possess beneficial effects on the prevention of oxidative stressinduced cell injury.

Asian Pacific Journal of Tropical Biomedicine published new progress about Borassus flabellifer. 2044-85-1 belongs to class esters-buliding-blocks, name is 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate, and the molecular formula is C24H14Cl2O7, Application of 2′,7′-Dichloro-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-diyl diacetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Anonymous published the artcileModified clerodanes from the essential oil of Dodonea viscosa leaves, Computed Properties of 6259-76-3, the main research area is Dodonea leaf essential oil clerodane computational model; Dodonea viscosa; bicyclo[5.4.0]undecane skeleton; density functional theory; electronic circular dichroism; essential oil; furanoid (nor)diterpenes.

Dodonea viscosa (L.) Jacq from Reunion Island (Indian Ocean) was investigated for its leaf essential oil composition The plant was extracted by hydrodistillation and its essential oil analyzed by gas chromatog. coupled to mass spectrometry. This study revealed that oxygenated norditerpenes and diterpenes were one of the major chem. classes (> 50%) mainly consisting of three modified cyclopropylclerodanes containing a bicyclo[5.4.0]undecane ring system: one new furanoid norditerpene, dodovisate C, and two furanoid diterpenes, the known Me dodovisate A and the new Me iso-dodovisate A. These three compounds were isolated by liquid chromatog. and their structures established on the basis of spectroscopic studies. The absolute configuration of dodovisate C was elucidated through a joint exptl. and theor. (B3LYP/6-311+G(d,p)) electronic CD study. The relative configurations of Me dodovisate A and Me iso-dodovisate A were determined using linear regressions of theor. chem. shifts vs. exptl. values with the (B3LYP/6-311+G(d,p)) method.

Molecules published new progress about Bond angle, dihedral. 6259-76-3 belongs to class esters-buliding-blocks, name is Hexyl 2-hydroxybenzoate, and the molecular formula is C13H18O3, Computed Properties of 6259-76-3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Seto, Ryota published the artcileSynthesis of block copolymers through umpolung or treatment of propagating end of living cationic polytetrahydrofuran, Computed Properties of 142-90-5, the main research area is living polytetrahydrofuran anionic radical block polymerization diblock copolymer.

Block copolymers containing polyTHF segments were synthesized by umpolung or propagating end of the cationic living polymer and successive anionic polymerization of methacrylates (RMAs) or radical polymerization of RMAs, acrylonitrile (AN), and styrene (St). Living polyTHF (poly-THF) was prepared by cationic polymerization of THF, whose propagation end was reduced by Sm(II) iodide (SmI2). Anionic polymerizations of RMAs were conducted by addition of the monomers to the reduced poly-THF to obtain poly(THF-b-RMAs). However, the 2-bromoisobutyrate group, which can act as an initiator of radical polymerization, was introduced to the cationic propagating end of poly-THF by adding Na 2-bromoisobutyrate. Block copolymers were synthesized by living radical polymerization of RMAs, St, or AN using the 2-bromoisobutyrate-capped poly-THF as a macroinitiator and Cu(I) bromide (CuBr) as a catalyst.

Polymer Bulletin (Heidelberg, Germany) published new progress about Block polymerization. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Computed Properties of 142-90-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dutta, Saikat published the artcileRecent Advances in the Value Addition of Biomass-Derived Levulinic Acid: A Review Focusing on its Chemical Reactivity Patterns, SDS of cas: 539-88-8, the main research area is review levulinic acid biomass chem reaction.

Levulinic acid (LA) is one of the most prominent biomass-derived chem. building blocks that can be transformed into specialty chems. like fuels, solvents, monomers for polymers, plasticizers, surfactants, agrochems., and pharmaceuticals. Over the past three decades, an enormous amount of research data have been acquired on the preparation and downstream value addition of LA, and these works have been reviewed. However, considering the astonishing number of publications appearing every year on LA derivatives, the periodical review of recent works focusing on unique aspects of chem. must be undertaken to critically evaluate the achievements to date, reassess the challenges, and recognize new opportunities. This review discusses the chem.-catalytic synthesis of various derivatives of LA by focusing on its functionalities and reactivity patterns. Recent literature on some crucial derivatives such as γ-valerolactone, 4,4-diphenolic acid, and Et levulinate have been tabulated and discussed. The synthetic interconversion between various derivatives, mechanistic insights, critical anal. of the reaction parameters toward selective preparation of various derivatives, and their potential com. applications have been elaborated using predominantly heterogeneous catalysts. A critical assessment of the relative advantages and shortcomings of the existing synthetic strategies for various derivatives of LA has been presented to enkindle fresh ideas.

ChemCatChem published new progress about Biochemical reaction. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, SDS of cas: 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics