Esters-buliding-blocks

Rader, Chris published the artcileBiobased Polyester-Amide/Cellulose Nanocrystal Nanocomposites for Food Packaging, Product Details of C8H14O4, the publication is Macromolecular Materials and Engineering (2021), 306(3), 2000668, database is CAplus.

The worldwide plastic waste production is steadily increasing, since the use of polymeric materials continues to rise. One area of particular high plastic consumption is food packaging. Flexible and rigid packaging films are typically made from petrochem.-sourced polymers, which are utilized because of their low cost, ductility, melt-processability, and gas barrier properties, but a major downside is their inability to biodegrade in a reasonable time. Packaging-relevant properties of nanocomposites based on polyester-amides (PEAs) are reported, which are chosen on account of their tunable crystallinity, biobased starting materials, and biodegradability. These polymers are synthesized via melt polycondensation of a building block made from caprolactone and 1,4-diaminobutane, with the addition of 1,4-butanediol and di-Me adipate. The fraction of the amide segment is varied between 25 and 75 mol%. The oxygen transmission rate (O₂TR) drops upon increasing the amide content from 1.6 × 105 to 2.9 × 10^-4 cm³ m^-2 d^-1 on account of increasing crystallinity. In order to improve the gas barrier properties further, nanocomposites of the PEAs and 1-10 weight% cellulose nanocrystals (CNCs) are prepared These nanocomposites have indeed lower O₂TR values than the neat PEAs, with reductions of as much as 50% for a CNC content of 10 weight%.

Macromolecular Materials and Engineering published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Product Details of C8H14O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Liang, Yutong published the artcileAging of Volatile Organic Compounds in October 2017 Northern California Wildfire Plumes, Recommanded Product: Methyl 3-phenyl-2-propenoate, the publication is Environmental Science & Technology, database is CAplus and MEDLINE.

In the western United States, the number and severity of large wildfires have been growing for decades. Biomass burning (BB) is a major source of volatile organic compounds (VOCs) to the atm. both globally and regionally. Following emission, BB VOCs are oxidized while being transported downwind, producing ozone, secondary organic aerosols, and secondary hazardous VOCs. In this research, we measured VOCs using proton transfer reaction time-of-flight mass spectrometry (PTR-ToF-MS) in an urban area 55-65 km downwind of the Oct. 2017 Northern California wildfires. Nonaromatic oxygenated compounds were the dominant component of BB VOCs measured. In the smoke plumes, the VOCs account for 70-75% of the total observed organic carbon, with the remainder being particulate matter (with a diameter of <2.5 μm, PM_2.5). We show that the correlation of VOCs with furan (primary BB VOC) and maleic anhydride (secondary BB VOC) can indicate the origin of the VOCs. This was further confirmed by the diurnal variations of the VOCs and their concentration-weighted trajectories. Oxidation during transport consumed highly reactive compounds including benzenoids, furanoids, and terpenoids and produced more oxygenated VOCs. Furthermore, wildfire VOCs altered the ozone formation regime and raised the O₃ levels in the San Francisco Bay Area.

Environmental Science & Technology published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, Recommanded Product: Methyl 3-phenyl-2-propenoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Takizawa, Toshiya published the artcileTotal synthesis of spiruchostatin A, a potent histone deacetylase inhibitor, Related Products of esters-buliding-blocks, the publication is Heterocycles (2008), 76(1), 275-290, database is CAplus.

Total synthesis of spiruchostatin A, a potent histone deacetylase inhibitor, was achieved. The method features (i) Julia-Kocienski olefination of a tetrazolyl sulfone with an appropriate aldehyde to install the requisite (E)-olefin unit, (ii) amide coupling to produce the key seco-acid, and (iii) subsequent macrolactonization employing Shiina reagent to efficiently construct the desired 15-membered macrocycle.

Heterocycles published new progress about 106391-88-2. 106391-88-2 belongs to esters-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Aldehyde, name is (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, and the molecular formula is C6H12O2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nakata, Yasukazu published the artcileA new type of main-chain liquid-crystal polymer derived from 4-hydroxybiphenyl-4-carboxylic acid and its smectic mesophase behavior, Quality Control of 50670-76-3, the publication is Journal of Materials Chemistry (1994), 4(11), 1699-703, database is CAplus.

A homologous series of polymers (PHBC-n) was prepared from 4′-hydroxybiphenyl-4-carboxylic acid and ω-bromoalkan-1-ols containing 5-9 CH₂ units which can serve as mesogen and flexible spacer groups, resp. The PHBC-n polymers are characterized by having 2 different linkage groups, ether and ester groups, to connect the biphenyl mesogen to the methylene spacer, and are considered to be a new type of main-chain liquid-crystal polymer. All polymers exhibit the enantiotropic smectic phase. The smectic behavior and structure were examined by differential scanning calorimetry, optical microscopic and x-ray diffraction methods, and are discussed in comparison with the corresponding data of the BB-n polyesters, which include only the ester linkage group.

Journal of Materials Chemistry published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Quality Control of 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zimra, Yael published the artcileButyric acid and pivaloyloxymethyl butyrate, AN-9, a novel butyric acid derivative, induce apoptosis in HL-60 cells, Formula: C10H18O4, the publication is Journal of Cancer Research and Clinical Oncology (1997), 123(3), 152-160, database is CAplus and MEDLINE.

It is shown that AN-9 and butyrate induce cell death by apoptosis. Exposure of HL-60 cells to butyrate and AN-9 decreased cell numbers and induced cell differentiation and the appearance of typical apoptotic features. Induction of apoptosis and/or differentiation was dependent on the concentration and the time of exposure to the drugs. The advantage of An-9 over butyrate was further confirmed. AN-9-induced apoptosis occurred after a shorter exposure and at lower drug concentrations than that induced by butyrate. Apoptosis by AN-9 was accompanied by reduction in Bcl-2 expression. Preincubation with antioxidants did not protect HL-60 cells from apoptosis induced by AN-9.

Journal of Cancer Research and Clinical Oncology published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C19H36BNO2Si, Formula: C10H18O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yamazaki, Tatsumi published the artcileAmino sugars. 127. The synthesis of uridine diphosphate N-acetylhexosamines and uridine 5′-(2-acetamido-2-deoxy-α-D-mannopyranosyluronic acid diphosphate), Formula: C14H19NO8, the publication is Canadian Journal of Chemistry (1981), 59(15), 2247-52, database is CAplus.

2-Methyl-(2-acetamido-3,4,6-trio-O-acetyl-1,2-dideoxy-β-D-mannopyrano)-[2,1-d]-2-oxazoline was efficiently converted into 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-mannopyranosyl phosphate (I), by treatment with dibenzyl phosphate, followed by catalytic hydrogenolysis of the benzyl groups. Similarly, 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl phosphate and -galactopyranosyl phosphate were synthesized from the resp. peracetyl oxazolines. In each case, the procedures for preparing the oxazoline, and conversion into the glycosyl phosphate, were modified to give high yields of pure products. I was coupled with 2′,3′-di-O-acetyluridine 5′-monophosphate by a modification of the mixed anhydride procedure, to give 2′,3′-di-O-acetyluridine 5′-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-mannopyranosyl diphosphate), which was readily purified by preparative TLC and O-deacetylated to give uridine diphosphate N-acetylmannosamine (II) in high yield. Similarly, uridine 5′-(2-acetamido-2-deoxy-α-D-glucopyranosyl- and -galactopyranosyl diphosphates) were synthesized by rapid, efficient procedures, not involving ion-exchange chromatog. II was converted into mannopyranosyluronic acid III, required for biosynthetic studies, without the preparation of a special Pt catalyst. All the synthetic uridine diphosphate sugars were characterized by optical rotation, ¹H NMR spectrum, and elemental anal.

Canadian Journal of Chemistry published new progress about 10378-06-0. 10378-06-0 belongs to esters-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Ester,Inhibitor,Inhibitor, name is (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, and the molecular formula is C25H34N4O2S, Formula: C14H19NO8.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhang, Ziyang published the artcileTi³⁺ Tuning the Ratio of Cu⁺/Cu⁰ in the Ultrafine Cu Nanoparticles for Boosting the Hydrogenation Reaction, SDS of cas: 627-93-0, the publication is Small (2021), 17(23), 2008052, database is CAplus and MEDLINE.

Hydrogenation of diesters to diols is a vital process for chem. industry. The inexpensive Cu⁺/Cu⁰-based catalysts are highly active for the hydrogenation of esters, however, how to efficiently tune the ratio of Cu⁺/Cu⁰ and stabilize the Cu⁺ is a great challenge. In this work, it is demonstrated that doped Ti ions can tune the ratio of Cu⁺/Cu⁰ and stabilize the Cu⁺ by the Ti-O-Cu bonds in Ti-doped SiO₂ supported Cu nanoparticle (Cu/Ti-SiO₂) catalysts for the high conversion of di-Me adipate to 1,6-hexanediol. In the synthesis of the catalysts, the Ti⁴⁺-O-Cu²⁺ bonds promote the reduction of Cu²⁺ to Cu⁺ by forming Ti³⁺-O_V-Cu⁺ (O_V: oxygen vacancy) bonds and the amount of Ti doping can tune the ratio of Cu⁺/Cu⁰. In the catalytic reaction, the O vacancy activates C-O in the ester by forming new Ti^3+δ-O_R-Cu^1+δ bonds (O_R: reactant oxygen), and Cu⁰ activates hydrogen. After the products are desorbed, the Ti^3+δ-O_R-Cu^1+δ bonds return to the initial state of Ti³⁺$-O_V-Cu⁺ bonds. The reversible Ti-O-Cu bonds greatly improve the activity and stability of the Cu/Ti-SiO₂ catalysts. When the content of Ti is controlled at 0.4 wt%, the conversion and selectivity can reach 100% and 98.8%, resp., and remain stable for 260 h without performance degradation

Small published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C9H9ClN2, SDS of cas: 627-93-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xu, Yan-Li published the artcileOrganocatalytic enantioselective electrophilic amination of benzoyl butyrolactones, HPLC of Formula: 517-23-7, the publication is Tetrahedron Letters (2022), 153745, database is CAplus.

Organocatalytic electrophilic amination of benzoyl butyrolactones with azodicarboxylates was demonstrated to highly efficiently prepare quaternary carbon stereocenter-bearing α-amino-γ-butyrolactones I [R = Me, Ph, OBn, etc.], key framework in numerous bioactive compounds The squaramide catalyst II realized the highest yield (99%) and enantioselectivity (93%).

Tetrahedron Letters published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C24H29N5O3, HPLC of Formula: 517-23-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Song, Runzhe published the artcileDesign and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity, Quality Control of 924-99-2, the publication is Bioorganic Chemistry (2020), 104176, database is CAplus and MEDLINE.

The desfluoroquinolone-based hybrids with involvement of C-7 aminopyrimidine functional group were designed and synthesized. The biol. results showed majority of these hybrids still demonstrated potent anti-MRSA activity with MIC values between 0.38 and 1.5μg/mL, despite the lack of the typical C-6 fluorine atom. Particularly, the most active 1-cyclopropyl-7-((4-(3,4-dimethylphenoxy)pyrimidin-2-yl) amino)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid exhibited activities at submicromolar concentrations against a panel of MRSA strains including vancomycin-intermediate strains, levofloxacin-resistant isolates, and linezolid-resistant isolates, etc. As expected, it also displayed highly selective toxicity toward bacterial cells and low hERG inhibition. Further resistance development study indicated MRSA is unlikely acquired resistance against 1-cyclopropyl-7-((4-(3,4-dimethylphenoxy)pyrimidin-2-yl)amino)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. The docking study revealed that two hydrogen bonds were formed between the C-7 substituent and the surrounding DNA bases, which contributed to resistance by reducing the dependence on the magnesium-water bridge interactions with topoisomerase IV. These indicated a promising strategy for developing new antibiotic quinolones to combat multidrug resistance and cardiotoxicity was resulted.

Bioorganic Chemistry published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C9H7NO3, Quality Control of 924-99-2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Kong, Xianqiang published the artcileCyanation and cyanomethylation of trimethylammonium salts via electrochemical cleavage of C-N bonds, SDS of cas: 10287-53-3, the publication is Organic Chemistry Frontiers (2022), 9(5), 1288-1294, database is CAplus.

A practical and mild electrochem. protocol for cyanation and cyanomethylation of trimethylammonium salts through a pathway involving C-N bond cleavage without the need for an external stoichiometric reducing agent or a sacrificial anode was developed. The reaction employed tosyl cyanide (TsCN) or azido allyl alc. as the cyanation or cyanomethylation reagent, resp. It showed high functional group compatibility and can be applied for the cyanation of natural product derivatives Preliminary mechanistic studies indicated the involvement of a radical addition pathway.

Organic Chemistry Frontiers published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, SDS of cas: 10287-53-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics