Esters-buliding-blocks

Kongkaew, A. published the artcileSynthesis of polyisoprene-poly(methyl methacrylate) block copolymers by using polyisoprene as a macro-iniferter, Formula: C12H17NS2, the publication is Polymer Bulletin (Berlin) (1999), 43(4-5), 327-332, database is CAplus.

Polyisoprene (PI) was prepolymerized by using benzyl diethyldithiocarbamate (BDC) as an iniferter. The obtained PI was subsequently used to react with Me methacrylate (MMA) in order to investigate whether the relevant block copolymers can be achieved. Results from ¹H-NMR and GPC reveal that the PI-PMMA block copolymers were formed. This suggests that polymerization of isoprene through the use of BDC proceeded via a (pseudo) “living” mechanism.

Polymer Bulletin (Berlin) published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Formula: C12H17NS2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Kongkaew, A. published the artcilePolymerization of isoprene by using benzyl diethyldithiocarbamate as an iniferter, COA of Formula: C12H17NS2, the publication is ScienceAsia (1999), 25(1), 35-41, database is CAplus.

The polymerization of isoprene using of benzyl N,N-diethyldithiocarbamate (BDC) as iniferter was investigated. The monomer concentration was kept constant at 2.8 mol/L while the BDC concentration was varied. The product, characterized by FTIR, ¹H-NMR and DSC, was mainly 1,4-polyisoprene. The mol. weight, polydispersity, and percentage yield of the polymer were affected by the BDC concentration The yield increased initially, and then decreased after a critical BDC concentration was reached. The mol. weightdecreased with BDC concentration The polydispersity was 1.8-4.7 and decreased with increasing BDC concentration

ScienceAsia published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, COA of Formula: C12H17NS2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Kongkaew, A. published the artcileEffects of reaction conditions on poly(methyl methacrylate) polymerized by living radical polymerization with iniferter, Safety of Benzyl diethylcarbamodithioate, the publication is Journal of Applied Polymer Science (2000), 75(7), 938-944, database is CAplus.

Living radical polymerization of Me methacrylate (MMA) through the use of benzyl diethyldithiocarbamate (BDC) was studied. The aim was to investigate the role of the concentration, BDC-to-MMA mol ratio, and reaction time upon the mol. weight, polydispersity, and conversion of the product. It was found that the mol. weight and the conversion increase with increase of the concentration at the expense of low polydispersity. The reaction time also played a significant role, especially at a relatively long reaction time where mol. weight, polydispersity, and conversion increased with increasing reaction time. In terms of the mol ratio effect, it was found that there was a critical mol ratio for maximum conversion. The results indicate that the kinetics of polymerization of MMA through the use of a BDC iniferter is different from that in the presence of a conventional initiator.

Journal of Applied Polymer Science published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Safety of Benzyl diethylcarbamodithioate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Atkinson, Benjamin N. published the artcileRegioselective and enantiospecific synthesis of the HSP co-inducer arimoclomol from chiral glycidyl derivatives, SDS of cas: 115314-17-5, the publication is Organic & Biomolecular Chemistry (2017), 15(46), 9794-9799, database is CAplus and MEDLINE.

A new efficient chiral synthesis of enantiopure arimoclomol is reported from (R)-(-)-glycidyl nosylate with complete retention of chiral integrity. Off-target pharmacol. of arimoclomol was evaluated against a representative set of drug targets and showed modest binding to a few kinases. Pharmacokinetic data was generated in vivo in mouse and showed a low brain : plasma ratio. These studies will be helpful towards a better understanding of the PK-PD relationship of arimoclomol in disease models.

Organic & Biomolecular Chemistry published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, SDS of cas: 115314-17-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nguyen, Duc H. published the artcileSolid-Supported MADIX Polymerization of Vinyl Acetate, Category: esters-buliding-blocks, the publication is Macromolecules (Washington, DC, United States) (2008), 41(19), 7071-7078, database is CAplus.

A simple, one-pot synthesis of a surface-tethered MADIX agent was established via the reaction of 1,1′-thiocarbonyl diimidazole (TCDI) with a thiol, followed by reaction with the hydroxyl groups of a Wang resin. The supported RAFT agent was used to control the polymerization of vinyl acetate in toluene. The amount of surface-bound polymer was found to greatly increase with increasing content of solid MADIX agent, reaching values of almost 80%. The grafted PVAc chains were cleaved from the Wang resin support via radical reaction with tert-amyl peroxy acetate (TAPA), and the mol. weight distributions exhibited the typical shape of polymers formed via a well-controlled living radical polymerization (LRP), with the free polymers showing a slightly higher mol. weight than the living fraction. The M_n values of both living polymer fraction (surface-bound polymer) and dead polymer (free polymer) increased steadily with monomer conversion-as expected for a well controlled MADIX polymerization-and were in good agreement with the theor. mol. weights PDI values of both polymer fractions scatter around 1.5, with a slight tendency of narrower mol. weight distributions of the living polymer, which shows a min. value of 1.43. Addition of free MADIX agent to the solution phase led to a decrease in PDI values of both free and bound polymer, and the exptl. molar masses were in good agreement with theor. predictions.

Macromolecules (Washington, DC, United States) published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C5H10O2S, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Burkhardt, George N. published the artcileNitroarylsulfuric acids and their reduction products, Product Details of C6H4KNO6S, the publication is Journal of the Chemical Society (1929), 141-52, database is CAplus.

ClSO₃H (1.4 mols.) was added to 3.7 mols. PhNMe₂ in 500 cc. CS₂ kept below 16°; to the mixture, heated to 35°, O₂NC₆H₄OH or O₂NC₁₀H₆OH (1 mol.) was added all at once; after stirring at 35° for 1 hrs., the product was poured into dilute KOH; details for the separation of the K salts are given. K o-nitrophenyl sulfate, solubility in H₂O at 17°6”; the p-isomer has the same solubility; K 1-nitro-2-naphthyl sulfate, pale yellow needles; the 4-nitro-1-naphthyl derivative forms fine, pale yellow needles. These are all rapidly hydrolyzed by very dilute HCl at 70° and slowly at 100° by 10% Ba(OH)₂, or dilute AcOH containing AcONa. Reduction with FeSO₄ in a suspension of CaCO₃ or BaCO₃ gives the corresponding NH₂ derivatives, which give Ac and benzylidene derivatives without loss of the SO₄ group. K o-aminophenyl sulfate, gives with Br a faint violet color; the p-isomer crystallines with 1 H₂O, gives a violet color with Br and with HCl or AcOH and H derivative; the K benzylidene derivative crystallines with 0.5 H₂O. K 1-amino-2-naphthyl sulfate, crystallines with 0.5 H₂O; solubility in H₂O at 17° 1.1%; Br gives a dirty green precipitate, changing to yellow with excess of Br; FeCl₃ gives an opalescence and then a blue precipitate, which changes to brown; HCl or AcOH precipitates the H derivative, needles. p-H₂NC₅H₄SO₄H yields a diazo compound, which couples with m-C₆H₄(OH)₂, giving K dihydroxybenzeneazophenyl sulfate, orange plates with 1.5 H₂O; boiling with dilute HCl splits off the HSO₄ group; the 2-hydroxynaphthalene derivative, dark red, crystallines with 0.5 H₂O; precipitates are formed with BaCl₂, CaCl₂, HgNO₃ and MgSO₄. Results of dye tests with wool are given. The SO₄H group is removed when it is o- to the NH₄ group, but the diazo oxide results. Alk. reduction of o-O₂NC₆H₄SO₄K gives a mixture of azo and hydrazo derivatives K azobenzene 2,2′-disulfate, orange plates with 0.5 H₂O, rapidly hydrolyzed at 70° by HCl. K hydrazobenzene 2,2′-disulfate, needles; solubility in H₂O at 19° 3.2%, at 32° 5.4%; a saturated solution at 20° with concentrated HCl deposits 4,4′-diaminodiphenylene di-H 3,3′-disulfate, needles with 2.5 H₂O; the K salt crysts, with 1 H₂O; characteristic reactions with Br and FeCl₃ are given. Diacetyldihydroxybenzidine, m. 292° (decomposition); heating at 300-20° for 0.75 hr. gives the dianhydro derivative, m. 164-5°; the same compound was prepared from the sulfate.

Journal of the Chemical Society published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Product Details of C6H4KNO6S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xie, Peizhong published the artcileCalcium-catalyzed regioselective dehydrative cross-coupling of propargylic alcohols with 1,3-dicarbonyl compounds, Synthetic Route of 517-23-7, the publication is Green Chemistry (2019), 21(19), 5207-5211, database is CAplus.

A novel calcium-catalyzed in situ dehydrative cross-coupling reaction of propargylic alcs. with 1,3-dicarbonyl compounds was developed. This catalytic system can suppress the competitive Meyer-Schuster rearrangement, control regioselectivity, and enable the desired process to occur under solvent-free conditions at room temperature with water as the only byproduct. A variety of vicinal tertiary and all-carbon quaternary centers can be obtained in high yields with broad functional group tolerance.

Green Chemistry published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C11H8O3, Synthetic Route of 517-23-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Francio, G. published the artcileHighly efficient enantioselective catalysis in supercritical carbon dioxide using the perfluoroalkyl-substituted ligand (R,S)-3-H²F⁶-BINAPHOS, Formula: C22H12F6O6S2, the publication is Journal of Organometallic Chemistry (2001), 621(1-2), 130-142, database is CAplus.

Perfluoroalkyl-substitution of the aryl groups in the BINAPHOS skeleton was achieved using a synthetic strategy based on the Cu(I)-catalyzed cross coupling of arylmagnesium bromide and F(CF₂)₆(CH₂)₂I. The rhodium complexes of the new ligand (R,S)-3-H²F⁶-BINAPHOS exhibited spectroscopic properties and reactivities similar to those of the unsubstituted parent compounds The substitution provided a high affinity of the ligand and its complexes for scCO₂ allowing the development of ecol. benign protocols for catalytic asym. synthesis and even the spectroscopic detection of catalytically active intermediates. Using this new system, a large variety of substrates were hydroformylated in scCO₂ with rates and enantioselectivities comparable to those of the parent system in benzene solution At the same time, the CO₂-philic substitution pattern resulted in a significantly higher regioselectivity towards the desired chiral aldehydes. Preliminary results indicated for the first time also a remarkable potential of BINAPHOS-derived ligands for asym. hydrogenation reactions. The possibility to develop new work-up schemes for product purification and/or catalyst immobilization based on scCO₂ as the only medium for catalysis and extraction (CESS process) was exptl. verified using a rhodium catalyst containing the title ligand.

Journal of Organometallic Chemistry published new progress about 126613-06-7. 126613-06-7 belongs to esters-buliding-blocks, auxiliary class Chiral Diphenols, name is (R)-[1,1′-Binaphthalene]-2,2′-diyl bis(trifluoromethanesulfonate), and the molecular formula is C22H12F6O6S2, Formula: C22H12F6O6S2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Maczka, Wanda published the artcileBiotransformation of α-acetylbutyrolactone in Rhodotorula strains, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one, the publication is International Journal of Molecular Sciences (2018), 19(7), 2106/1-2106/11, database is CAplus and MEDLINE.

Due to its structural similarity, the α-1-hydroxyethyl-γ-butyrolactone obtained by reduction of (±)-α-acetyl-γ-butyrolactone may have a similar function in the body to γ-butyrolactone (GBL). In the work presented, biotransformation of α-acetyl-γ-butyrolactone by three Rhodotorula strains was performed obtaining enantiomerically enriched alc. The process was carried out in growing and resting cultures. We studied how both media composition and organic solvent volume affected stereoselectivity and effectiveness of biotransformation. After 2 h, the enantiomerically pure (3R, 1 S)-α-1-hydroxyethyl-γ-butyrolactone was obtained using the R. marina AM77 strain in YPG (Yeast extract-Peptone-Glucose) medium enriched with 5% glycerol. To our best knowledge there is no previous information in the literature about the (±)-α-acetyl-γ-butyrolactone biotransformation performed in medium with addition of organic and deep eutectic solvents.

International Journal of Molecular Sciences published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C6H8O3, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Holman, Samuel D. L. published the artcileElectrochemical Synthesis of Isoxazolines: Method and Mechanism, Quality Control of 624-49-7, the publication is Chemistry – A European Journal (2022), 28(13), e202103728, database is CAplus and MEDLINE.

An electrochem. method for the green and practical synthesis of a broad range of substituted isoxazoline cores is presented. Both aryl and more challenging alkyl aldoximes are converted to the desired isoxazoline in an electrochem. enabled regio- and diastereoselective reaction with electron-deficient alkenes. Addnl., in-situ reaction monitoring methods compatible with electrochem. equipment have been developed in order to probe the reaction pathway. Supporting analyses from kinetic (time-course) modeling and d. functional theory support a stepwise, radical-mediated mechanism, and discounts hypothesised involvement of closed shell [3+2] cycloaddition pathways.

Chemistry – A European Journal published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C6H8O4, Quality Control of 624-49-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics