Category: esters-buliding-blocks

A new small molecule gelator and 3D framework ligator of lead(II) was written by Knichal, Jane V.;Gee, William J.;Burrows, Andrew D.;Raithby, Paul R.;Wilson, Chick C.. And the article was included in CrystEngComm in 2015.Reference of 313648-56-5 This article mentions the following:

Reacting equimolar quantities of 5-allenyl-1,3-benzenedicarboxylic acid (H₂abd) with lead(II) acetate trihydrate in N,N-dimethylformamide (DMF) under solvothermal conditions gave a metallogel with a critical gelation percentage of 1% weight/volume Elemental anal. performed on the gel provided a mol. composition ratio of [Pb(abd)(H₂O)]_n (1). Viewing the gel by SEM identified an entangled network of crosslinked nano-fibers. ¹H-NMR aliquots of hydrated lead(II) acetate added to a solution of H₂abd in deuterated DMF allows inferences to be made about solution-state behavior that occurs during the initial gel aggregation stage. Under non-solvothermal conditions, combining H₂abd and hydrated lead(II) acetate gave single crystals suitable for x-ray diffraction, which were identified as a 3D coordination polymer with composition [Pb(abd)(DMF)] (2). Structural features observed within this 3D coordination polymer provide the basis for assigning the mol. structure to the fibrils present within gel 1. This assertion is supported by comparable vibrational profiles taken from a sample of dried gel 1 to that of crystalline 2, and the matching of early solution-state ¹H-NMR spectroscopic trends to later solid-state observations. In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Reference of 313648-56-5).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Reference of 313648-56-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synergistic Catalysis for the Umpolung Trifluoromethylthiolation of Tertiary Ethers was written by Xu, Wentao;Ma, Junyang;Yuan, Xiang-Ai;Dai, Jie;Xie, Jin;Zhu, Chengjian. And the article was included in Angewandte Chemie, International Edition in 2018.COA of Formula: C7H8O2S This article mentions the following:

The first transition-metal-free, site-specific umpolung trifluoromethylthiolation of tertiary alkyl ethers has been developed, achieving the challenging tertiary C(sp³)-SCF₃ coupling under redox-neutral conditions. The synergism of organophotocatalyst 4CzIPN and BINOL-based phosphorothiols can site-selectively cleave tertiary sp³ C(sp³)-O ether bonds in complex mols. initiated by a polarity-matching hydrogen-atom-transfer (HAT) event. The incorporation of several competing benzylic and methine C(sp³)-H bonds in alkyl ethers has little influence on the regioselectivity. Selective difluoromethylthiolation of C-O bonds has also been achieved. This represents not only an important step forward in trifluoromethylthiolation but also a promising means for site-selective C-O bond functionalization of unsym. tertiary alkyl ethers. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9COA of Formula: C7H8O2S).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.COA of Formula: C7H8O2S

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bio-augmented effect of Bacillus amyloliquefaciens and Candida versatilis on microbial community and flavor metabolites during Chinese horse bean-chili-paste fermentation was written by Lu, Yunhao;Yang, Linzi;Yang, Guohua;Chi, Yuanlong;He, Qiang. And the article was included in International Journal of Food Microbiology in 2021.Electric Literature of C10H18O2 This article mentions the following:

Chinese horse bean-chili-paste (CHCP), a fermented condiment in China, is traditionally manufactured through naturally spontaneous semi-solid fermentation procedures without intentionally inoculated microorganisms. The aim of this study was to investigate the effect on microbiota and quality variations during CHCP fermentation by inoculation of selected autochthonous microorganisms Bacillus amyloliquefaciens and Candida versatilis. The results showed that relative abundance of Bacillus in the samples inoculated with B. amyloliquefaciens were increased from about 0.6% to almost 25%, and the batches bio-augmented with C. versatilis exhibited clearly 0.7 Lg copies/g higher biomass than that of the other samples. By bio-augmentation, six enzyme activities, namely acid protease, leucine aminopeptidase, α-amylase, cellulose, β-glucosidase and esterase, were considerably enhanced. As a result, inoculation of these two strains exhibited significant effect on the volatile profiles of CHCP. B. amyloliquefaciens herein was found to contribute mainly to the accumulation of acids, sulfur-containing compounds and pyrazines, whereas C. versatilis was considerably associated with the formation of alcs., esters and phenols. This study proved that combination of B. amyloliquefaciens and C. versatilis could obtain more extensive aroma profiles, especially for the enrichment of miso-like and fruity flavors, which could provide a guideline for the tailored control of CHCP fermentation process. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Electric Literature of C10H18O2).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Electric Literature of C10H18O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cu-Catalyzed Aminodifluoroalkylation of Alkynes and α-Bromodifluoroacetamides was written by Lv, Yunhe;Pu, Weiya;Chen, Qian;Wang, Qingqing;Niu, Jiejie;Zhang, Qian. And the article was included in Journal of Organic Chemistry in 2017.Application of 185619-66-3 This article mentions the following:

The copper-catalyzed highly regioselective aminodifluoroalkylation of alkynes and α-bromodifluoroacetamides was realized for the first time. With this method, 3,3-difluoro-1H-pyrrol-2(3H)-ones were constructed in a single step from various alkynes and α-bromodifluoroacetamides substrates without using any extra oxidant. In the experiment, the researchers used many compounds, for example, tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3Application of 185619-66-3).

tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 185619-66-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Palladium catalyzed reactions of unsaturated carbohydrates. A route to C-glycosides was written by Engelbrecht, Gerhardus J.;Holzapfel, Cedric W.. And the article was included in Heterocycles in 1991.Formula: C10H14O4 This article mentions the following:

Glycosyl carbonates e.g., I, are excellent substrates for palladium catalyzed stereoselective C-glycosidations with active methylene compounds giving the C-glycosides in good yields under mild conditions. Thus, I was treated with NaMeC(CO₂Et)₂ in the presence of Pd(PPh₃)₄-PPh₃ to give >70% the C-glycoside II. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Formula: C10H14O4).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Formula: C10H14O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Manganese and rhenium-catalyzed selective reduction of esters to aldehydes with hydrosilanes was written by Wei, Duo;Buhaibeh, Ruqaya;Canac, Yves;Sortais, Jean-Baptiste. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020.Electric Literature of C10H11FO2 This article mentions the following:

The selective reduction of esters RC(O)OR¹ [R = (4-chlorophenyl)methyl, naphthalen-2-ylmethyl, nonyl, etc.; R¹ = Me, Et] to aldehydes RC(O)H (I), via the formation of stable alkyl silyl acetals RCH(OSi(C₂H₅)₃)OR¹ (II), for the first time, was achieved with both manganese, -Mn₂(CO)₁₀– and rhenium -Re₂(CO)₁₀– catalysts in the presence of triethylsilane as reductant. These two methods provide a direct access to a large variety of aliphatic and aromatic alkyl silyl acetals II and to the corresponding aldehydes I upon hydrolysis. The reactions proceeded in excellent yields and high selectivity at room temperature under photo-irradiation conditions (LED, 365 nm, 40 W, 9 h). In the experiment, the researchers used many compounds, for example, Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2Electric Literature of C10H11FO2).

Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Electric Literature of C10H11FO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

GC-MS analyses of volatile compounds of steamed breads fermented by Chinese traditional starter “Jiaozi” from different regions was written by Wang, Yuan-Hui;Zhao, Jing-Wen;Xu, Fei;Zhang, Qi-Dong;Ai, Zhi-Lu;Li, Bo-Yu. And the article was included in Journal of Food Processing and Preservation in 2021.SDS of cas: 695-06-7 This article mentions the following:

The volatile compounds of Jiaozi-steamed breads (JSBs) fermented by Jiaozi starters from eight regions in China were extracted using simultaneous distillation and extraction (SDE) and headspace solid-phase microextraction and determined using gas chromatog.-mass spectrometry (GC-MS). 1-Hexanol, 3-methyl-1-butanol, phenylethyl alc., benzaldehyde, naphthalene, ethanol, acetic acid, and n-hexadecanoic acid were the main volatiles of JSBs. Principal component anal. exhibited that the volatiles of JSBs from Nanyang City, Xi’an City, and Zhumadian City was neg. correlated to that of other five JSB samples. Cluster anal. demonstrated that the volatile characteristics of JSBs from Heze City, Minqin County, Taian City, Weinan City, and Yuncheng City belonged to a category, and the JSBs of Nanyang City, Xi’an City, and Zhumadian City were different from other five JSBs. It demonstrated that the volatile components of steamed breads in North China and South China were different. From this study, it can be seen that simultaneous distillation and extraction (SDE) can completely extract volatile compositions of steamed breads fermented by Chinese traditional starter “Jiaozi” SDE/GC-MS was suitable for the anal. of JSBs volatile composition The relative contents of 1-hexanol, 3-methyl-1-butanol, phenylethyl alc., benzaldehyde, naphthalene, ethanol, acetic acid, and n-hexadecanoic acid in JSBs were at high level, and their contents could be used as a marker to identify JSBs. The volatile compositions of JSBs made of Jiaozi starters from Heze City, Minqin County, Taian City, Weinan City, and Yuncheng City were similar. However, JSBs of Nanyang City, Xi’an City, and Zhumadian City were different from other five JSBs. The volatile components of steamed breads in North China and South China were different, which reflected the difference in dietary habit in the southern and northern areas of China. In the experiment, the researchers used many compounds, for example, 5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7SDS of cas: 695-06-7).

5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.SDS of cas: 695-06-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Metathesis cascade strategies (ROM-RCM-CM): a DOS approach to skeletally diverse sultams was written by Jeon, Kyu Ok;Rayabarapu, Dinesh;Rolfe, Alan;Volp, Kelly;Omar, Iman;Hanson, Paul R.. And the article was included in Tetrahedron in 2009.Quality Control of (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate This article mentions the following:

The development of a ring-opening metathesis/ring-closing metathesis/cross-metathesis (ROM-RCM-CM) cascade strategy to the synthesis of a diverse collection of bi- and tricyclic sultams is reported. In this study, functionalized sultam scaffolds derived from intramol. Diels-Alder (IMDA) reactions undergo metathesis cascades to yield a collection of tricyclic sultams, e.g. I. Addnl. appendage-based diversity was achieved by utilizing a variety of CM partners. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Quality Control of (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate).

(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Quality Control of (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Two Functional Porous Metal-Organic Frameworks Constructed from Expanded Tetracarboxylates for Gas Adsorption and Organosulfurs Removal was written by Luo, Xiaolong;Kan, Liang;Li, Xiang;Sun, Libo;Li, Guanghua;Zhao, Jun;Li, Dong-Sheng;Huo, Qisheng;Liu, Yunling. And the article was included in Crystal Growth & Design in 2016.Recommanded Product: Dimethyl 5-ethynylisophthalate This article mentions the following:

Two fof-type porous metal-organic frameworks (MOFs), [Cu₂(bdfdpa)(H₂O)₂]·8DMF·2H₂O (JLU-Liu29) and [Cu₂(btadpa)(H₂O)₂]·7DMF·8H₂O (JLU-Liu30) (H₄bdfdpa = 5,5′-(benzo[1,2-b:4,5-b’]difuran-2,6-diyl)diisophthalic acid and H₄btadpa = 5,5′-(benzo[c][1,2,5]thiadiazole-4,7-diylbis(ethyne-2,1-diyl))diisophthalic acid), have been successfully synthesized by using different expanded tetracarboxylate ligands. Both of them exhibit good permanent porosity and high surface areas of 2205 and 1791 m²g^-1, resp. Due to open metal sites, different functional groups, and suitable pore spaces, the two porous MOFs exhibit high adsorption performance for small mol. gases (CO₂, CH₄, C₂H₆, and C₃H₈) and removal of refractory organosulfur compounds In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Recommanded Product: Dimethyl 5-ethynylisophthalate).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: Dimethyl 5-ethynylisophthalate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lipase-catalyzed synthesis of polymeric prodrugs of nonsteroidal anti-inflammatory drugs was written by Qian, Xueqi;Wu, Qi;Xu, Fangli;Lin, Xianfu. And the article was included in Journal of Applied Polymer Science in 2013.Formula: C12H22O4 This article mentions the following:

Because of the potential application of prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs), Candida antarctica lipase B (CAL-B) catalyzed polycondensation of profen-containing diol monomers and diesters were designed to prepare a series of biodegradable polymeric prodrugs composed of NSAID branches and poly(amide-co-ester) backbone. The structure of the products was confirmed by Fourier transform IR spectroscopy, NMR, and gel permeation chromatog. (GPC). The reaction conditions of polymerization, such as the enzyme source, amount of catalyst, and temperature, were optimized. The mol. weights of resultant copolymers were 2170-13,270 g/mol, with corresponding polydispersities from 1.17 to 2.4. The copolymers had relatively high drug loadings of 44.7-59.7 wt % because every repeat unit contained one drug mol. The strategy of enzymic polymerization appeared to be quite general and accommodated a large number of comonomer substrates with various chain lengths and substituents. The optically pure (R)-naproxen monomer was demonstratively incorporated into the corresponding copolymers with the developed synthesis strategy. The in vitro study showed that the polyester could release the drug effectively under physiol. conditions with enzyme, which indicated that the obtained product could be a promising prodrug for extending pharmacol. effects by delayed drug release. With GPC anal., we confirmed that the prodrug was completely degradable in aqueous solution The attractive features of the copolymer were its high drug loading, biodegradability, and biocompatibility. The high tolerance of the CAL-B toward drug groups, as described in this article, provides a new route for synthesizing polymeric drugs with potential biomedical applications in mild conditions and for reducing environmental impact. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2012. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Formula: C12H22O4).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Formula: C12H22O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics