esters-buliding-blocks Archives - Page 915 of 2796

Trovato, Emanuela et al. published their research in Separations in 2021 | CAS: 112-14-1

Octyl acetate (cas: 112-14-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Category: esters-buliding-blocks

Influence of citrus flavor addition in brewing process: characterization of the volatile and non-volatile profile to prevent frauds and adulterations was written by Trovato, Emanuela;Arigo, Adriana;Vento, Federica;Micalizzi, Giuseppe;Dugo, Paola;Mondello, Luigi. And the article was included in Separations in 2021.Category: esters-buliding-blocks The following contents are mentioned in the article:

In the last few years, the flavored beer market has increased significantly. In particular, consumers showed a growing interest in citrus-flavored beers. Citrus fruits contain, among other class of compounds, terpenes and terpenoids and oxygenated heterocyclic compounds The absence of a specific legislation concerning beer flavored production and ingredients reported on the labels makes these beers subject to possible adulterations. Solid phase micro extraction (SPME) followed by gas chromatog.-mass spectrometry (GC-MS) and gas chromatog.-flame ionization detector (GC-FID) anal. of the volatile profile together with the characterization of the oxygen heterocyclic compounds through high performance liquid chromatog. coupled to tandem mass spectrometry (HPLC-MS/MS) demonstrated to be a powerful anal. strategy for quality control. In this study, we combined the volatile and non-volatile profiles of ”citrus flavored mainstream beers”, in order to evaluate the authenticity and determine markers to prevent food frauds. The changes in the aroma composition of the unflavored types after the addition of peel, or citrus essential oil were also evaluated. The linear retention index (LRI) system was used for both techniques; in particular, its application in liquid chromatog. is still limited and represents a novelty. The coupling of the high sensitivity of the HPLC MS/MS method with the LRI system, it has made possible for the first time a reliable identification and an accurate quantification of furocoumarins in citrus-flavored beers. This study involved multiple reactions and reactants, such as Octyl acetate (cas: 112-14-1Category: esters-buliding-blocks).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mehanna, Mai et al. published their research in Metabolites in 2021 | CAS: 26662-94-2

(2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate (cas: 26662-94-2) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 26662-94-2

Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients was written by Mehanna, Mai;McDonough, Caitrin W.;Smith, Steven M.;Gong, Yan;Gums, John G.;Chapman, Arlene B.;Johnson, Julie A.;McIntyre, Lauren;Cooper-DeHoff, Rhonda M.. And the article was included in Metabolites in 2021.Product Details of 26662-94-2 The following contents are mentioned in the article:

Plasma renin activity (PRA) is a predictive biomarker of blood pressure (BP) response to antihypertensives in European-American hypertensive patients. We aimed to identify the metabolic signatures of baseline PRA and the linkages with BP response to β-blockers and thiazides. Using data from the Pharmacogenomic Evaluation of Antihypertensive Responses-2 (PEAR-2) trial, multivariable linear regression adjusting for age, sex and baseline systolic-BP (SBP) was performed on European-American individuals treated with metoprolol (n = 198) and chlorthalidone (n = 181), to test associations between 856 metabolites and baseline PRA. Metabolites with a false discovery rate (FDR) < 0.05 or p < 0.01 were tested for replication in 463 European-American individuals treated with atenolol or hydrochlorothiazide. Replicated metabolites were then tested for validation based on the directionality of association with BP response. Sixty-three metabolites were associated with baseline PRA, of which nine, including six lipids, were replicated. Of those replicated, two metabolites associated with higher baseline PRA were validated: caprate was associated with greater metoprolol SBP response (β = -1.7 ± 0.6, p = 0.006) and sphingosine-1-phosphate was associated with reduced hydrochlorothiazide SBP response (β = 7.6 ± 2.8, p = 0.007). These metabolites are clustered with metabolites involved in sphingolipid, phospholipid, and purine metabolic pathways. The identified metabolic signatures provide insights into the mechanisms underlying BP response. This study involved multiple reactions and reactants, such as (2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate (cas: 26662-94-2Product Details of 26662-94-2).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kurrimboccus, Fadilah et al. published their research in Planta Medica in 2022 | CAS: 31566-31-1

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 31566-31-1

Antimicrobial Formulation of Chrysopogon zizanioides Essential Oil in an Emulsified Lotion for Acne was written by Kurrimboccus, Fadilah;Orchard, Ane;Danckwerts, Michael Paul;van Vuuren, Sandy. And the article was included in Planta Medica in 2022.SDS of cas: 31566-31-1 The following contents are mentioned in the article:

Acne is a skin condition arising from excess sebum production and microbial overgrowth within the pilosebaceous unit. Several com. essential oils have shown promising activity against acne-related pathogens. Due to their volatility and thermal instability, the formulation of essential oils into com. products remains a pharmaceutical challenge. Thus, this study aimed to develop a viable anti-acne topical treatment as an oil-in-water emulsified lotion to overcome these challenges. Chrysopogon zizanioides(vetiver) displayed noteworthy antimicrobial activity with a mean min. inhibitory concentration of 0.14 mg/mL against Cutibacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus pyogenes. Emulsified lotions containing C. zizanioideswere developed through the hydrophilic-lipophilic balance approach. At tested hydrophilic-lipophilic balance values of 8, 9, and 10, C. zizanioidesemulsified lotions displayed maximum stability at hydrophilic-lipophilic balance 9 with a min. change in mean droplet size and polydispersity index of 20.61 and 33.33%, resp., over 84 days. The C. zizanioidesemulsified lotion at optimum hydrophilic-lipophilic balance 9 completely inhibited the growth of C. acnesand killed S. aureus, S. epidermidis, and S. pyogeneswithin 24 h. Addnl., the lotion retained antimicrobial activity against these test micro-organisms over the 84-day stability test period. Thus, the C. zizanioidesemulsified lotion demonstrated phys. stability and antimicrobial efficiency, making it an ideal natural product anti-acne treatment. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1SDS of cas: 31566-31-1).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bubmann, Tobias et al. published their research in Polymers (Basel, Switzerland) in 2022 | CAS: 102-09-0

Diphenyl carbonate (cas: 102-09-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: Diphenyl carbonate

Transparent PC/PMMA Blends with Enhanced Mechanical Properties via Reactive Compounding of Functionalized Polymers was written by Bubmann, Tobias;Seidel, Andreas;Ruckdaeschel, Holger;Altstaedt, Volker. And the article was included in Polymers (Basel, Switzerland) in 2022.Name: Diphenyl carbonate The following contents are mentioned in the article:

Reactive compounding of terminally phenolic OH-functionalized polycarbonate (PC) with epoxy-functionalized polymethylmethacrylate (PMMA) prepared by copolymerization with glycidyl methacrylate was investigated. It was spectroscopically demonstrated that a PC/PMMA copolymer was formed during the melt reaction of the functional groups. Zirconium acetylacetonate could catalytically accelerate this reaction. Correlations of the phenomenol. (optical and mech.) properties with the mol. level and mesoscopic (morphol.) structure were discussed. By the investigated reactive compounding process, transparent PC/PMMA blends with two-phase morphologies were obtained in a continuous twin-screw extruder, which, for the first time, combined the high transmission of visible light with excellent mech. performance (e.g., synergistically improved tensile and flexural strength and high scratch resistance). The transparency strongly depended on (a) the degree of functionalization in both PC and PMMA, (b) the presence of the catalyst, and (c) the residence time of the compounding process. The in-situ-formed PC/PMMA copolymer influenced the observed macroscopic properties by (a) a decrease in the interphase tension, leading to improved and stabilized phase dispersion, (b) the formation of a continuous gradient of the polymer composition and thus of the optical refractive indexes in a diffuse mesoscopic interphase layer separating the PC and PMMA phases, and (c) an increase in the phase adhesion between PC and PMMA due to mech. polymer chain entanglement in this interphase. This study involved multiple reactions and reactants, such as Diphenyl carbonate (cas: 102-09-0Name: Diphenyl carbonate).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Perestrelo, Rosa et al. published their research in Microchemical Journal in 2019 | CAS: 763-69-9

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Product Details of 763-69-9

Untargeted fingerprinting of cider volatiles from different geographical regions by HS-SPME/GC-MS was written by Perestrelo, Rosa;Silva, Catarina L.;Silva, Pedro;Medina, Sonia;Pereira, Regina;Camara, Jose S.. And the article was included in Microchemical Journal in 2019.Product Details of 763-69-9 The following contents are mentioned in the article:

The volat. fingerprint of ciders produced in different geog. regions from Madeira Island was established using headspace solid phase microextraction combined with gas chromatog. mass spectrometry (HS-SPME/GC-MS) in order to explore the effects of geog. region on the volatile pattern ciders in addition to identify potential mol. geog. markers. A total of 107 volatile organic compounds (VOCs) belonging to different chem. families were identified from which 50 VOCs are common to all ciders analyzed. Significant differences in the relative content of VOCs from ciders of different geog. regions were observed The potential of the identified VOCs for ciders discrimination according to region was assessed through chemometric tools, such as principal components anal. (PCA) and partial least squares-discriminant anal. (PLS-DA). The PCA showed significant differences among ciders from different island geog. regions. Fifteen VOCs responsible for ciders discrimination were identified by PLS-DA. Fifteen VOCs, namely five terpenoids, four alcs., three acids and three esters, present variable importance in projection (VIP) values higher than one. Our findings provide relevant information related to volatile signature of ciders produced in Madeira Island, which may be a useful tool to cider-making process contributing to improve the quality of the final product. In addition, the geog. discrimination recognizes the unique and distinctive characteristics that will allow in the future to protect the quality and typicity of products originating in certain geog. regions. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Product Details of 763-69-9).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fang, Cuifen et al. published their research in Molecules in 2022 | CAS: 2198-61-0

Isopentyl hexanoate (cas: 2198-61-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 2198-61-0

Development of the Volatile Fingerprint of Qu Aurantii Fructus by HS-GC-IMS was written by Fang, Cuifen;He, Jia;Xiao, Qi;Chen, Bilian;Zhang, Wenting. And the article was included in Molecules in 2022.SDS of cas: 2198-61-0 The following contents are mentioned in the article:

Volatile components are important active ingredients of Rutaceae. In this study, HS-GC-IMS (headspace-gas chromatog.-ion mobility spectrometry) was used to study the volatile compounds of Qu Aurantii Fructus, and a total of 174 peaks were detected, 102 volatile organic compounds (131 peaks) were identified. To compare the volatile compounds of Qu Aurantii Fructus with its similar medical herb, Aurantii Fructus, and their common adulterants, principal component anal. (PCA) and cluster anal. (CA) were performed based on the signal intensity of all the detected peaks. The results showed that Qu Aurantii Fructus and Aurantii Fructus (Citrus aurantium L.) were clustered into one group, while their common adulterants could be well distinguished in a relatively independent space. In order to distinguish Qu Aurantii Fructus from Aurantii Fructus, the peaks other than the average intensity ±2 standard deviation (95% confidence interval) were taken as the characteristic components by using the Gallery Plot plug-in software. Addnl., the fingerprint method was established based on the characteristic compounds, which can be used to distinguish among Qu Aurantii Fructus, Aurantii Fructus and their common adulterants quickly and effectively. We found that the characteristic components with higher content of Qu Aurantii Fructus were nerol, decanal, coumarin and linalool. This study provides a novel method for rapid and effective identification of Qu Aurantii Fructus and a new dimension to recognize the relationship between Qu Aurantii Fructus and Aurantii Fructus. This study involved multiple reactions and reactants, such as Isopentyl hexanoate (cas: 2198-61-0SDS of cas: 2198-61-0).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Loganathan, T. et al. published their research in Journal of Drug Delivery and Therapeutics in 2021 | CAS: 2253-73-8

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Quality Control of Isopropylisothiocyanate

GCMS profile of bioactive secondary metabolites with therapeutic potential in the ethanolic leaf extracts of Azadirachta indica: a sacred traditional medicinal plant of INDIA was written by Loganathan, T.;Barathinivas, A.;Soorya, C.;Balamurugan, S.;Nagajothi, T. G.;Ramya, S.;Jayakumararaj, R.. And the article was included in Journal of Drug Delivery and Therapeutics in 2021.Quality Control of Isopropylisothiocyanate The following contents are mentioned in the article:

Neem (Azadirachta indica) a member of Meliaceae plays an immense role in human health and disease which is attributed to its composition of Bioactive Secondary Metabolites (BASM). It has been widely used in Indian Traditional Systems of Medicine that includes Ayurveda, Siddha, Unani, Homeopathy and other Folklore Systems of Medicine practiced in the Indian Subcontinent for the treatment and prevention of various diseases. Current global health perspectives and medical practice in the post COVID era has no other way but to seek to merge alternative systems of medicine with evidence-based therapeutic aspects for a better understanding of the metabolic process and its effects in the human body. The studies based on animal model established that neem and its chief constituents play pivotal role in anticancer management through the modulation of various mol. pathways including p53, pTEN, NF-κB, PI3K/Akt, Bcl-2, and VEGF. Besides, NEEM plays a vital role in the management of diabetics and its associated long term complication through ROS scavenging and ameliorative potentials to restore oxidative injury/ inhibit enzymes linked to. Overall NEEM is considered as GRAS medicinal plant that modulates metabolic inflammations without side effects. Though it has been confirmed that neem and its constituents play role in the scavenging of free radical and prevention of disease pathogenesis, a clear scientific basis of its pharmacoinformatics is still lacking. Gas Chromatog.-Mass Spectroscopy (GC-MS) anal. of the fractions revealed the presence of 62 metabolites. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Quality Control of Isopropylisothiocyanate).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Loganathan, T. et al. published their research in Journal of Drug Delivery and Therapeutics in 2021 | CAS: 2253-73-8

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Quality Control of Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Banchero, Mauro et al. published their research in Molecules in 2018 | CAS: 763-69-9

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 763-69-9

Comparison between multi-linear- and radial-basis-function-neural-network-based QSPR models for the prediction of the critical temperature, critical pressure and acentric factor of organic compounds was written by Banchero, Mauro;Manna, Luigi. And the article was included in Molecules in 2018.SDS of cas: 763-69-9 The following contents are mentioned in the article:

Critical properties and acentric factor are widely used in phase equilibrium calculations but are difficult to evaluate with high accuracy for many organic compounds Quant. Structure-Property Relationship (QSPR) models are a powerful tool to establish accurate correlation between mol. properties and chem. structure. QSPR multi-linear (MLR) and radial basis-function-neural-network (RBFNN) models have been developed to predict the critical temperature, critical pressure and acentric factor of a database of 306 organic compounds RBFNN models provided better data correlation and higher predictive capability (an AAD% of 0.92-2.0% for training and 1.7-4.8% for validation sets) than MLR models (an AAD% of 3.2-8.7% for training and 6.2-12.2% for validation sets). The RMSE of the RBFNN models was 20-30% of the MLR ones. The correlation and predictive performances of the models for critical temperature were higher than those for critical pressure and acentric factor, which was the most difficult property to predict. However, the RBFNN model for the acentric factor resulted in the lowest RMSE with respect to previous literature. The close relationship between the three properties resulted from the selected mol. descriptors, which are mostly related to mol. electronic charge distribution or polar interactions between mols. QSPR correlations were compared with the most frequently used group-contribution methods over the same database of compounds: although the MLR models provided comparable results, the RBFNN ones resulted in significantly higher performance. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9SDS of cas: 763-69-9).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lagas, M. et al. published their research in Pharmaceutisch Weekblad in 1982 | CAS: 5003-48-5

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.HPLC of Formula: 5003-48-5

Wettability and availability of drugs was written by Lagas, M.. And the article was included in Pharmaceutisch Weekblad in 1982.HPLC of Formula: 5003-48-5 The following contents are mentioned in the article:

Water did not penetrate pellets prepared from powd. phenytoin [57-41-0] or hexobarbital (I) [56-29-1], whereas aqueous solutions of the surfactant, polysorbate 80 [9005-65-6], penetrated at a rate which depended on the polysorbate concentration (0.1-1.0%). If the drugs were rendered hydrophilic by prior mixing of the powder with a 3% Me cellulose [9004-67-5] solution and drying before compression, penetration of water, surfactant solutions, or gastric juice was practically instantaneous. The disintegration time of hard gelatin capsules containing I was 2 h in water, 15 min in 1% polysorbate 80, and 3 min (corresponding to the gelatin dissolution time) for hydrophilic I independent of the polysorbate concentration Similarly, the dissolution rate of the I capsules was increased by polysorbate and was greatest for hydrophilic I. In human subjects, 100% disintegration of capsules of hydrophilic benorilate [5003-48-5] occurred in the stomach within 60 min, as detected by release of a ⁹⁹^mTc label; disintegration of nonhydrophilic benorilate capsules was very slow. Absorption of I, phenytoin, and benorilate in humans was more rapid and resulted in higher plasma concentrations when the drugs were administered in capsules in the hydrophilic than in the nonhydrophilic forms. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5HPLC of Formula: 5003-48-5).

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics