Category: esters-buliding-blocks

Synthesis of novel photoactive enkephalin-like peptides was written by Sumbatyan, N. V.;Topin, A. N.;Taranenko, M. V.;Korshunova, G. A.. And the article was included in Vestnik Moskovskogo Universiteta, Seriya 2: Khimiya in 2001.Recommanded Product: 133467-01-3 This article mentions the following:

Two new analogs of enkephalin containing photoactive residue of N-azide-L-phenylalanine and N-[3-(trifluoromethyl)-3H-diazirin-3-yl]-L-phenylalanine were synthesized. The photochem. property of prepared enkephalin derivatives and their ability to bind opioid receptors were studied. In the experiment, the researchers used many compounds, for example, Boc-D-Leu-OMe (cas: 133467-01-3Recommanded Product: 133467-01-3).

Boc-D-Leu-OMe (cas: 133467-01-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 133467-01-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Highly efficient [2 + 2] intramolecular cyclizations of allenynes under microwave irradiation: construction of fused bicyclic compounds was written by Oh, Chang Ho;Gupta, Arun Kumar;Park, Dai In;Kim, Nakjoong. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2005.Quality Control of Diethyl 2-(prop-2-yn-1-yl)malonate This article mentions the following:

A palladium [2 + 2] cycloaddition of 1,6- and 1,7- allenyne carboxylates and microwave-mediated [2 + 2] cycloaddition of various 1,n-allenynes were developed and, particularly, the microwave irradiated [2 + 2] cycloaddition of allenynes can provide a simple, general and eco-friendly synthetic method to fused bicyclo[m,2,0]alkadienes. E.g., microwave irradiation of allenyne CH₂:C:CHCH₂N(Ts)CH₂CCCO₂Et gave 89% bicyclo[m,2,0]alkadiene I. In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Quality Control of Diethyl 2-(prop-2-yn-1-yl)malonate).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of Diethyl 2-(prop-2-yn-1-yl)malonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Volatile components of Borassus aethiopum was written by Mahmout, Yaya;Mbaiguinam, Mbailao;Bessiere, Jean-Marie. And the article was included in Journal de la Societe Ouest-Africaine de Chimie in 2001.Recommanded Product: Ethyl 2-hydroxy-3-phenylpropanoate This article mentions the following:

The essential oil and the methylene chloride extract of the pulp of B. aethiopum of Chad were analyzed. The essential yield of the samples was 0.5-0.7%, while methylene chloride extracts gave 1.3% of the residue. The essential oil was characterized by (E)-Et cinnamate and geranylacetone (10.5%) with lesser amounts of 3-phenylpropanol (8.6%) and farnesylacetone (5%). The other main esters were Et 3-hydroxybutanoate (3.4%), Et 3-phenylpropanoate (2.7%), Et benzoate (1.7%), (E)-Me cinnamate (0.8%), Et 3-hydroxyisohexanoate (0.6%) and phenylethyl tiglate (0.6%). The richness of ester compounds may have contributed significantly to the pleasant odor of the ripe fruits of B. aethiopum. The presence of (E)-Et cinnamate in the oil of B. aethiopum was the most major difference noticed on comparison of the essential oil of samples from Sudan. Most of the identified components were not previously known to be present in the volatile extracts of B. aethiopum. These compositional differences may be chemotaxonomically significant. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Recommanded Product: Ethyl 2-hydroxy-3-phenylpropanoate).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: Ethyl 2-hydroxy-3-phenylpropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Facile synthesis of δ-ketoesters via formal two-carbon insertion into β-ketoesters was written by Jiang, Yan;Xi, Song;Wang, Qi;Fu, Lin;He, Ling;Wang, Zhen;Zhang, Min. And the article was included in Tetrahedron Letters in 2022.Category: esters-buliding-blocks This article mentions the following:

A formal two-carbon insertion into β-ketoesters with vinylmetal has been developed for the rapid synthesis of δ-ketoesters. This method features high efficiency, simple operation, and mild conditions without the usage of bases and catalysts. The reaction is postulated to proceed via a tandem process in volving nucleophilic addition of vinylmetal to ketone, retro-aldol reaction to give an enolate anion and an enone, and finally Michael addition of these two intermediates. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Category: esters-buliding-blocks).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The carboxyl group. Infrared absorption and ionization was written by Peltier, Daniel;Pichevin, Annick. And the article was included in Bulletin de la Societe Chimique de France in 1960.Application of 81245-24-1 This article mentions the following:

PK, ν_OH(monomeric), and ν_C:O (monomeric and dimeric) values of 17 substituted benzoic, 34 o-toluic, 17 m-toluic, and 12 p-toluic acids, as well as the ν_C:O values of 55 Me and Et esters were tabulated. For all the acids except the 6-substituted o-toluic acids (6-NO₂, I, Br, Cl, OH, NH₂), ν_OH (cm.^-1) = 3498 + 9pK. The ν_C:O (monomeric) of the o-OH and o-NH₂ acids were on the average 55 cm.^-1 lower and those of nonchelated, 6-substituted o-toluic acids were approx. 5 cm.^-1 higher than calculated from the appropriate equations (CA 53, 17954e). For acids free of chelation and steric effects, ν_OH = 5,028 – 0.857 ν_C:O (monomeric) (cm.^-1). For 3-, 4-, and 5-substituted o-toluic acids, ν_OH = 5053 – 0.874 ν_C:O. The carbonyl frequencies of the Et esters were approx. 5 cm.^-1 lower than those of the corresponding Me esters. These results are explained by electronic effects of H or alkyl group on the carbonyl group. 6-HO(or H₂N)-2-MeC₆H₃CO₂Me exhibited 2 carbonyl frequencies related to chelated and nonchelated forms. Similar data were presented for 2,3- (I), 2,4-, and 2,6-(MeO)MeC₆H₃CO₂H, and o-MeOC₆H₄CO₂H. The dimeric carbonyl absorptions were weak, the ν_OH were lower, and the ν_C:O were higher, based on the relations with pK, than expected for nonchelated acids. I was exceptional, as it gave a strong dimeric carbonyl absorption. In the experiment, the researchers used many compounds, for example, Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1Application of 81245-24-1).

Methyl 2-methoxy-4-methylbenzoate (cas: 81245-24-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 81245-24-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rapid analysis of 13 phthalates in textiles by Py-GC-MS method was written by Bao, Haifeng;Zhao, Hailang;Tan, Yujing. And the article was included in Yinran in 2021.Category: esters-buliding-blocks This article mentions the following:

A method for rapid determination of 13 phthalates in textiles by pyrolysis gas chromatog. mass spectrometry (Py GC-MS) was established. The optimized anal. conditions of the pyrolyzer were the initial temperature of 200 °C, heating to 350 °C at 50 °C/min, holding for 2 min. The linear correlation coefficient was R²>0.99, the detection limit was 0.08-6.17 mg/kg, the recovery was 89.2-97.1%, and the relative standard deviation was 1.2-4.4% (n = 6). The method is simple, rapid, accurate and reliable, which can meet the daily detection requirements of 13 phthalates in textiles. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Category: esters-buliding-blocks).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Iron Catalyzed Asymmetric Hydrogenation of Ketones was written by Li, Yanyun;Yu, Shenluan;Wu, Xiaofeng;Xiao, Jianliang;Shen, Weiyi;Dong, Zhenrong;Gao, Jingxing. And the article was included in Journal of the American Chemical Society in 2014.Safety of Ethyl 3-oxo-3-(m-tolyl)propanoate This article mentions the following:

Chiral mols., such as alcs., are vital for the manufacturing of fine chems., pharmaceuticals, agrochems., fragrances, and novel materials. These mols. need to be produced in high yield and high optical purity and preferentially catalytically. Among all the asym. catalytic reactions, asym. hydrogenation with H₂ (AH) is the most widely used in the industry. With few exceptions, these AH processes use catalysts based on the three critical metals, rhodium, ruthenium, and iridium. Herein we describe a simple, industrially viable iron catalyst that allows for the AH of ketones, a process currently dominated by ruthenium and rhodium catalysts. By combining a chiral, 22-membered macrocyclic ligand with the cheap, readily available Fe₃(CO)₁₂, a wide variety of ketones have been hydrogenated under 50 bar H₂ at 45-65°, affording highly valuable chiral alcs. with enantioselectivities approaching or surpassing those obtained with the noble metal catalysts. In contrast to AH by most noble metal catalysts, the iron-catalyzed hydrogenation appears to be heterogeneous. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Safety of Ethyl 3-oxo-3-(m-tolyl)propanoate).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Safety of Ethyl 3-oxo-3-(m-tolyl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Photolactonization: a novel synthetic entry to macrolides was written by Quinkert, Gerhard;Billhardt, Uta Maria;Jakob, Harald;Fischer, Gerd;Glenneberg, Juergen;Nagler, Peter;Autze, Volker;Heim, Nana;Wacker, Manfred. And the article was included in Helvetica Chimica Acta in 1987.COA of Formula: C11H14O3 This article mentions the following:

o-Quinol acetates, hydroxyalkylated at C-6 (e.g., I), are easily accessible from simple phenols by Wessely acetoxylation (preferentially catalyzed by BF₃). On UV irradiation (in the presence of an appropriate tertiary amine), they are smoothly converted to macrocyclic lactones, e.g., II. Subtle conditions were elaborated to lead to high overall yields, and the scope of the conversion of phenols to macrolides was elucidated. In the experiment, the researchers used many compounds, for example, Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7COA of Formula: C11H14O3).

Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C11H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Volatile compositions of strawberry fruit during shelf life using pre and postharvest hexanal treatment was written by Oz, Ayse Tuelin;Kafkas, Ebru. And the article was included in Journal of Food Processing and Preservation in 2022.Product Details of 706-14-9 This article mentions the following:

Changes in volatile compositions were determined in Rubygem strawberry variety related to pre and postharvest hexanal application during shelf life. For this concern, Rubygem variety was treated with hexanal vapor and spray applications which were, doses (0%, 0.01%, 0.02%) pre and postharvest after hexanal applications strawberry fruits were stored at 2°C and RH 90% conditions. Effects of hexanal spray and vapor applications of strawberry fruit volatile profiles were analyzed with HS-SPME/GC-MS techniques. Differences among treatments were identified in volatile compositions at 3 days intervals during 15 days of shelf life. The results showed that, hexanal application type and concentration effected the percentage of volatile composition of esters, ketones, terpens, alcs., acids, aldehydes, and others during shelf life. The hexanal application form and concentration were effected the amount and composition of volatiles of Rubygem strawberry fruit. As a result, hexanal spray application has important effects on ester percentage, however, hexanal vapor treatment increased the alcs. percentage of strawberries at the end of shelf life. Practical applications : Application of organic substances of hexanal pre and postharvest season has been successfully used due to their environmentally friendly effects. Hexanal is volatile gases, organic aldehydes which are the source of plant extract and used as food additives. There are many research on hexanal application to prevent microbial growth after harvest. In the present study, hexanal spray and vapor applications were used to determined the volatiles profile strawberries fruit during shelf life. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Product Details of 706-14-9).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 706-14-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An Improved Preparation of Arylboronates: Application in One-Pot Suzuki Biaryl Synthesis was written by Zhu, Lei;Duquette, Jason;Zhang, Mingbao. And the article was included in Journal of Organic Chemistry in 2003.HPLC of Formula: 525362-07-6 This article mentions the following:

The Miyaura arylboronate synthesis was modified by substituting a ligandless palladium catalyst for PdCl₂(dppf). Palladium acetate, free of ligand, was highly effective for these coupling reactions. This modified procedure is advantageous over the original Miyaura synthesis in ease of workup, catalyst removal, and low catalyst cost. Furthermore, the boronates formed in this manner can be used directly for Suzuki coupling reactions in a one-pot fashion. The biaryl products have improved impurity profiles and reduced heavy metal contamination. Thus, 4-BrC₆H₄COMe and bis(pinacolato)diboron reacted in DMF containing Pd(OAc)₂ and KOAc for 2-3 h at 80° and the cooled reaction mixture treated with 4-BrC₆H₄NO₂ in the presence of cesium carbonate and Pd(PPh₃)₄ at 80° overnight to give 1-(4′-nitrobiphenyl-4-yl)ethanone in >99% yield and >95% purity. In the experiment, the researchers used many compounds, for example, Methyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 525362-07-6HPLC of Formula: 525362-07-6).

Methyl 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (cas: 525362-07-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.HPLC of Formula: 525362-07-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics