Category: esters-buliding-blocks

Phosphine-mediated domino reactions of phthalimidomalonates with allenoates or but-2-ynoate: facile entry into highly functionalized pyrroloisoindolinone derivatives was written by Huang, Zhusheng;Chen, Qingqing;Yang, Xiuqin;Liu, Yang;Zhang, Li;Lu, Tao;Zhou, Qingfa. And the article was included in Organic Chemistry Frontiers in 2017.Related Products of 1190-39-2 This article mentions the following:

A phosphine-mediated domino reaction between phthalimidomalonates and allenoates furnishes highly functionalized pyrroloisoindolinone derivatives, e.g., I, in synthetically useful yields. When Et but-2-ynoate was reacted with phthalimidomalonates under the same conditions, pyrroloisoindolinone derivatives were also obtained in good to excellent yields. The mechanism for the transformation is a tandem γ-umpolung/Wittig/γ-umpolung process. The present domino reaction not only exploits the potential of allenoates, but also extends the existing phosphine-mediated cyclization scope. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Related Products of 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Related Products of 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hybrid nanocomposites of a fluorescent block copolymer and quantum dots: An efficient way for energy transfer was written by Moura, I.;de Sa, A.;Abreu, Ana S.;Oliveira, M.;Machado, A. V.. And the article was included in Dyes and Pigments in 2017.Safety of Benzyl benzodithioate This article mentions the following:

Forster resonance energy transfer (FRET) phenomenon has great potential in several applications, whose efficiency is dependent on the energy transfer between a suitable pair of fluorophores. In this work, a new block copolymer, PS-b-PS(co-pyren-1-yl), with fluorescent properties, was synthesized and used as donor component in the fluorophores pair copolymer/cadmium telluride quantum dots (CdTe QDs). Thus, water-soluble CdTe QDs, previously transferred into organic phase, by replacing the stabilizer ligands, thioglycolic acid by 1-dodecanethiol (1-DDT), were used to prepare a new hybrid nanocomposite. FRET studies between the fluorescent copolymer and CdTe-DDT QDs revealed that this fluorophores pair can experience FRET with an efficiency of 48%, being an efficient antenna system for light harvesting applications. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Safety of Benzyl benzodithioate).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of Benzyl benzodithioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Direct Fluoro-aminosulfenylation of Active Methylenes by Dialkylaminosulfur Trifluorides under Catalyst-Free Conditions was written by Saidalimu, Ibrayim;Guo, Ming;Tokunaga, Etsuko;Shibata, Norio. And the article was included in Asian Journal of Organic Chemistry in 2016.Recommanded Product: 13669-10-8 This article mentions the following:

The direct fluoro-aminosulfenylation of active methylene compounds, e.g., 2-(2,3-dihydro-1H-inden-1-ylidene)malononitrile by diethylaminosulfur trifluoride and its derivatives F₃SR (R = dimethylamino, diethylamino, bis(2-methoxyethyl)amino, morpholino) has been disclosed. A variety of α-fluorinated α-sulfenamides with a tetrasubstituted carbon center, e.g., I were synthesized from active methylene compounds under mild reaction conditions. This direct fluoro-aminosulfenylation reaction occurs very smoothly under metal-free and base-free conditions. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Recommanded Product: 13669-10-8).

Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 13669-10-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dipyridyl amines: Potent metabotropic glutamate subtype 5 receptor antagonists was written by Kamenecka, Theodore M.;Bonnefous, Celine;Govek, Steven;Vernier, Jean-Michel;Hutchinson, John;Chung, Janice;Reyes-Manalo, Grace;Anderson, Jeffery J.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2005.Reference of 14667-47-1 This article mentions the following:

Modulation of the metabotropic glutamate subtype 5 (mGluR5) receptor may be useful in the treatment of a variety of central nervous system disorders. Here, the discovery, synthesis, and biol. evaluation of dipyridyl amines as small mol. mGluR5 antagonists, is reported. In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1Reference of 14667-47-1).

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Reference of 14667-47-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis, film-forming properties, and thermal and light sensitivity of N,N’-bis[4-hydroxy(alkoxy, acyloxy)-3-alkoxyphenylmethylidene]benzene-1,4-diamines was written by Dikusar, E. A.;Kozlov, N. G.;Potkin, V. I.;Azarko, V. A.;Yuvchenko, A. P.. And the article was included in Russian Journal of General Chemistry in 2008.Quality Control of 4-Formyl-2-methoxyphenyl isobutyrate This article mentions the following:

Previously unknown E,E-isomeric Schiff bases were synthesized by reaction of p-phenylenediamine with 4-hydroxy-3-methoxybenzaldehyde, 3-ethoxy-4-hydroxybenzaldehyde, and their O-alkyl and O-acyl derivatives in anhydrous methanol. Film-forming properties and thermal and light sensitivity of the products were studied. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4Quality Control of 4-Formyl-2-methoxyphenyl isobutyrate).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Quality Control of 4-Formyl-2-methoxyphenyl isobutyrate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ruthenium-catalyzed stereospecific benzylic alkylation of optically active benzyl esters with malonate nucleophiles was written by Tsuji, Hiroaki;Suzuki, Koki;Kawatsura, Motoi. And the article was included in Tetrahedron Letters in 2021.Name: Diethyl isobutylmalonate This article mentions the following:

Herein, the study for the ruthenium-catalyzed benzylic alkylation of chiral benzyl esters with malonates as a carbon nucleophile was described. A combination of [Cp*RuCl₂]₂ and picolinic acid found to be effective for the title reaction, provided the chiral benzylic alkylation products with retention of stereochem. of the starting material. The ruthenium catalysis was proceed via a double inversion mechanism was proposed. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Name: Diethyl isobutylmalonate).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Name: Diethyl isobutylmalonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Understanding the aroma diversity of Dancong tea (Camellia sinensis) from the floral and honey odors: Relationship between volatile compounds and sensory characteristics by chemometrics was written by Chen, Wei;Hu, Die;Miao, Aiqing;Qiu, Guangjun;Qiao, Xiaoyan;Xia, Hongling;Ma, Chengying. And the article was included in Food Control in 2022.Quality Control of 5-Ethyldihydrofuran-2(3H)-one This article mentions the following:

Dancong is a Chinese oolong tea famous for its aroma diversity. However, this diversity in characteristic is challenging to be clarified in either sensory or chem. aspects. In this study, the aromas from Dancong teas were characterized based on the typical odors of “floral” and “honey”. The volatile compounds underlying the odors were investigated through chemometrics. Seventy Dancong teas of various categories were collected to approx. the diversity in aroma. According to the sensory evaluation, the floral or honey odor was detected in every sample. For volatile characterization, 57 compounds were identified by gas chromatog.-mass spectrometry (GC-MS) coupled with headspace-solid phase microextraction (HS-SPME) across samples. The difference in floral and honey odors was related to volatile variation among the teas, as both the odor-based classification and the volatile-based unsupervised learning analyses yielded consistent sample clustering patterns. Nine volatiles were identified as putative markers for the odor difference, where indole, (E)-nerolidol, 2-phenylacetonitrile, and γ-caprolactone accounted for the floral odor predominance, while hexyl 2-methylbutanoate, (Z)-3-hexenyl pentanoate, (Z)-linalool oxide (pyranoid), (E)-linalool oxide (furanoid), and (Z)-linalool oxide (furanoid) contributed to the honey odor perception. These results point to a volatile-endorsed categorization framework based on the floral and honey odors that can assist in Dancong aroma quality control. In the experiment, the researchers used many compounds, for example, 5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7Quality Control of 5-Ethyldihydrofuran-2(3H)-one).

5-Ethyldihydrofuran-2(3H)-one (cas: 695-06-7) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Quality Control of 5-Ethyldihydrofuran-2(3H)-one

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Palladium-Catalyzed C2-Regioselective Perfluoroalkylation of the Free (NH)-Heteroarenes was written by Qin, Hong;Zhang, Jie;Qiao, Kai;Zhang, Dong;He, Wei;Liu, Chengkou;Fang, Zheng;Guo, Kai. And the article was included in Journal of Organic Chemistry in 2021.Formula: C8H11NO2 This article mentions the following:

A highly regioselective and atom-efficient strategy for the construction of fused free (NH) heteroarenes I (R = 3-Me, 4-Cl, 7-F, etc.) and II (R¹ = 2-C(O)₂Me, 3-C(O)₂Me, 3-C(O)₂Et-4-Me) through a palladium-catalyzed perfluoroalkyl insertion reaction has been accomplished. This protocol employed multiple iodofluoroalkanes R²I [R² = 1,2,2,3,3,4,4,5,5,6,6-undecafluorocyclohexyl, 1,1,2,2,3,3,3-heptafluoropropyl, (benzenesulfonyl)difluoromethyl, etc.] as practical and available perfluoroalkyl sources to provide an operationally simple and versatile route for the synthesis of perfluoroalkylated indoles III. Moreover, indoles I without the assistance of guide groups were utilized as substrates, achieving C(sp2)-H site-selective functionalization of indoles I in yields up to 95%. Furthermore, this protocol was also used for late-stage C2 perfluoroalkylation of bioactive compounds such as auxin, tryptophan, and melatonin analogs. In the experiment, the researchers used many compounds, for example, Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7Formula: C8H11NO2).

Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C8H11NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A Physical-chemical Synergetic Inhibitor for Coal Spontaneous Combustion and Its Fire Prevention Performance was written by Cai, Jiawen;Yang, Shengqiang;Zhong, Yan;Song, Wanxin;Zheng, Wancheng. And the article was included in Combustion Science and Technology in 2022.Product Details of 6683-19-8 This article mentions the following:

A single phys. or chem. inhibitor can hardly meet the uttermost requirements for coal spontaneous combustion prevention. Therefore, it has become essential to develop an efficient inhibitor with multiple inhibitory properties. In light of studies on the properties of the super absorbent polymer (SAP), the main antioxidant pentaerythritol tetrakys 3-(3,5-ditert-butyl-4-hydroxyphenyl) propionate and auxiliary antioxidant tris (2,4-di-tert-butyl-pheny) phosphite, a synergistic antioxidant with both phys. and chem. inhibitory properties was prepared According to the determination of volatile matter and calorific value of coal, the optimum molar ratio of the compound antioxidant (main antioxidant: auxiliary antioxidant = 2:1) was selected. Furthermore, the optimum formulation ratio (SAP: antioxidant = 1:3) and the optimum mass ratio (12%) were determined, taking the low-temperature oxygen consumption and cross-point temperature (CPT) of coal as indexes. Three grades of metamorphic coal were selected to obtain the gaseous product, oxygen consumption at 70°C, CPTs and inhibition rate. The addition inhibitor reduced the release of CO and C₂H₄ gas and oxygen consumption, while it raised CPTs and inhibition rate of coal oxidation The inhibiting capacity of MgCl₂ is mainly at low-temperature stage, while the synergistic inhibitor has excellent congenerous phys. and chem. effect in the whole coal oxidation process. In the experiment, the researchers used many compounds, for example, 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8Product Details of 6683-19-8).

2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 6683-19-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Amidinyl Radical Formation through Anodic N-H Bond Cleavage and Its Application in Aromatic C-H Bond Functionalization was written by Zhao, Huai-Bo;Hou, Zhong-Wei;Liu, Zhan-Jiang;Zhou, Ze-Feng;Song, Jinshuai;Xu, Hai-Chao. And the article was included in Angewandte Chemie, International Edition in 2017.Reference of 16413-26-6 This article mentions the following:

We report herein an atom-economical and sustainable approach to access amidinyl radical intermediates through the anodic cleavage of N-H bonds. The resulting nitrogen-centered radicals undergo cyclizations with (hetero)arenes, followed by rearomatization, to afford functionalized tetracyclic benzimidazoles, e.g., I (X-rays crystal structure shown), in a highly straightforward and efficient manner. This metal- and reagent-free C-H/N-H cross-coupling reaction exhibits a broad substrate scope and proceeds with high chemoselectivity. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Reference of 16413-26-6).

3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Reference of 16413-26-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics