Category: esters-buliding-blocks

Nedele, Ann-Kathrin published the artcileCharacterization of cheesy odor formed during fermentation of soy drink with Agrocybe aegerita, Computed Properties of 140-11-4, the main research area is cheesy odor fermentation soy drink Agrocybe; Agrocybe aegerita; Cheesy flavor; Fermentation; Short-chain fatty acids; Soy drink.

The market for plant protein-based substitutes for cheeses is growing, but the sensory properties are distinctively different from the original products. Hence, natural and vegan cheesy flavors are needed to aromatize the products. A cheesy, sweaty and parmesan-like aroma was produced by fermentation of soy drink with Agrocybe aegerita. Aroma dilution anal. revealed short-chain fatty acids (SCFAs) as main influencing cheesy odorants analyzed by gas chromatog.-mass spectrometry-olfactometry. In comparison to the five cheese varieties, the SCFA profile of the fermented soy drink revealed similarities with Parmesan and Emmental cheese. Meanwhile, principal component anal. showed an approximation of the aroma profile after fermentation with A. aegerita to those of cheeses. 3-Methylbutanoic acid was synthesized from the protein fraction, while the oil fraction contributed to the formation of unbranched SCFAs like butanoic acid. Accordingly, the production of these compounds can be increased by addition of the fractions.

Food Chemistry published new progress about Cyclocybe aegerita. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Computed Properties of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Dong-Hao published the artcileAsymmetric Reductive Amination of Structurally Diverse Ketones with Ammonia Using a Spectrum-Extended Amine Dehydrogenase, Application of Ethyl 4-oxopentanoate, the main research area is asym reductive amination reductive engineered amine dehydrogenase.

Amine dehydrogenase-catalyzed reductive amination of prochiral ketones with ammonia is a promising method for the synthesis of optically pure amines in the pharmaceutical and fine chem. industries. However, previously reported amine dehydrogenases show restricted catalytic capacity toward bulky ketones, which limits their widespread applications toward the production of chiral amines. Herein, we expanded the substrate scope of an engineered amine dehydrogenase GkAmDH from Geobacillus kaustophilus via laboratory evolution for the reductive amination of an extensive set of ketones. Several beneficial mutants were identified with a up to 2.2 U mg-1 activity toward bulky benzylacetone, 110-fold higher than that of M0. Using the engineered M3 and M8, structurally diverse bulky chiral amines could be synthesized with up to >99% conversion, >99% ee, and up to 18,900 TON. Among them, two key chiral intermediates used in the synthesis of the drugs medroxalol and dilevalol were produced on a gram scale in up to 85% yield and >99% ee. Addnl., the engineered enzymes M3 and M8 displayed considerable thermostability with a half-life of more than three days at 50 °C. These results demonstrate that these engineered amine dehydrogenases are promising biocatalysts for the synthesis of chiral amines. Mol. dynamics simulations provide insights into how mutations improve the amination activity toward bulky ketones and the thermostability.

ACS Catalysis published new progress about Directed evolution. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Application of Ethyl 4-oxopentanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

do Nascimento, Fernando H. published the artcileFast construction of polymer monolithic columns inside fluorinated ethylene propylene (FEP) tubes for separation of proteins by reversed-phase liquid chromatography, Recommanded Product: Dodecyl 2-methylacrylate, the main research area is polymer monolithic column fluorinated ethylene propylene protein RPHPLC; Egg white; Fluoropolymer tubes; Liquid chromatography; Monolithic columns; Photografting; Urine.

This paper describes the preparation of polymer monolithic columns in the confines of fluorinated ethylene propylene (FEP) tubes. These tubes are cheap, chem. stable, and widely used in flow anal. laboratories UV-initiated grafting with 5% benzophenone in methanol for 1 h activated the internal surface walls, thus enabling the further covalent binding of ethylene glycol dimethacrylate (EDMA) from a 15% solution in methanol, also via photografting. Both steps used 254 nm radiation under a potency of 120 mJ cm2. ATR-FTIR measurements revealed carbonyl, alkyl and vinyl groups in the functionalized FEP. The d. of vinyl groups was high enough to firmly attach a poly(lauryl methacrylate-coethylene glycol dimethacrylate) monolith in 120 × 1.57 mm internal diameter tubes, prepared via photopolymerization The total preparation lasts <2-h. The columns were permeable, (1.58 ± 0.06) x 10-13 m2, providing reproducible chromatog. parameters of retention times, retention factor, selectivity, and resolution The monoliths were stable at flow rates of 500μL min-1, collapsing only at flow rates >700μL min-1, a condition that increased the backpressure over 1000 psi (experiments at the room temperature). The separation of proteins by reversed-phase liquid chromatog. demonstrated the efficiency of the columns. Determination of egg white proteins (ovalbumin and lysozyme) and myoglobin in spiked urine proved the applicability to the anal. of real samples.

Talanta published new progress about Egg white, poultry. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Recommanded Product: Dodecyl 2-methylacrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kfoury, Miriana published the artcileContribution of headspace to the analysis of cyclodextrin inclusion complexes, Category: esters-buliding-blocks, the main research area is cyclodextrin inclusion complex headspace.

Headspace technol. is a sampling method of a gas, which has been previously in contact with a liquid or a solid matrix from which volatiles were released into the gaseous phase. It is generally coupled to a subsequent gas chromatog. anal. The headspace anal. can be carried out either as a one-step extraction (static or equilibrium headspace) or as a continuous extraction (dynamic headspace). The static headspace gas chromatog. (SH-GC) is gaining an increasing interest for the study of cyclodextrin (CD) inclusion complexes with volatile compounds CDs are natural supermol. hosts able to encapsulate volatile compounds and improve their functionalities (e.g. solubility, stability, retention, controlled release). Herein, the application of the SH-GC in the CD field will be reviewed. This paper will focus on the characterization of the inclusion complexes via the SH-GC, mainly aiming at the determination of formation constant (Kf) and encapsulation efficiency (EE%) values. Moreover, it will review the application of the SH-GC to monitor the properties of volatile compounds upon encapsulation (e.g. retention, controlled release).

Journal of Inclusion Phenomena and Macrocyclic Chemistry published new progress about Formation constant. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wei, Zheng published the artcileVolatile aroma compounds in wines from Chinese wild/hybrid species, Safety of Methyl decanoate, the main research area is volatile aroma compound wine; Chinese wild/hybrid species; HS-SPME/GC-MS; PCA; volatile compounds; wines.

The volatile aroma compounds in wines produced from Chinese wild/hybrid species were investigated in comparison to wines from European grapes. Volatiles were extracted by headspace solid-phase micro-extraction and identified by gas-chromatog./mass-spectrometry. The identification of analyte was performed by a combination of the linear retention index approach with the comparison of the obtained mass spectra. A total of 98 peaks were tentatively assigned as wine aroma components, and 15 odorants can be found at concentrations above their odor threshold among the odor activity values (OAVs) of 46 compounds evaluated in all of the wines. The “”OAVsâ€?aroma wheels”” showed that the classes of aromatic series are first fruity, next herbaceous and roasty and no spicy and caramelized notes. Via principal component anal., all the grape germplasm studied could be divided into four groups: “”Jingsheng-1,”” “”Cabernet Gernischt,”” “”Beibinghong,”” and others, which exhibited distinctive aroma features, resp. Practical applications Chinese wild grape species have many desirable properties for wine grape breeding such as possessing strong resistant genes to fungal diseases and cold condition, especially after hybridization with European grapes. As an emerging wine country, wines from Chinese wild/hybrid species have achieved much success in the last few years. The chem. content and biol. properties have been studied extensively in many but there are a few studies in our knowledge about the wine tastes of these species. In this paper, the key odorants in wines produced from the Chinese grape species of V. amurensisRupr., V. davidiiFoex., and V. quinquangularisRehd. and its hybrids were characterized in comparison to wines produced from European grapes (V. vinifera). The findings will help to the further understanding of the key aroma components in the different Chinese grapevine germplasm, and make further efforts to enrich the wine types in the marketplace.

Journal of Food Biochemistry published new progress about Gas chromatography. 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, Safety of Methyl decanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ng, Felicia published the artcileCharacterization of volatile compounds in Ylang-Ylang essential oils from Comoros and Madagascar by gas chromatography and principal component analysis, Quality Control of 140-11-4, the main research area is Ylang essential oil gas chromatog volatile compound.

Chem. composition of ylang-ylang essential oil is affected by the geog. origins of flowers used for extraction This study aimed to determine the compositional difference between the extra, first and third grades of ylang-ylang essential oil from Comoro Islands and Madagascar. The oils were characterized by both gas chromatog.-mass spectrometry (GC-MS) and gas chromatog.-flame ionization detector (GC-FID) in conjunction with principal component anal. (PCA). A total of 124 volatile compounds were identified and quantified by GC-MS and GC-FID. Twenty-two compounds that made up 85% to 90% of the oils were shortlisted to compare across grades and geog. origins. The PCA showed that the ylang-ylang essential oils are clustered according to grade and origin based on their compositions Anal. of variance was performed to determine the statistical significance of the differences between each compound across extra, first and third grades of ylang-ylang essential oil from Madagascar and Comoros. The oils of Madagascar are dominating in geranyl acetate, cis-α-farnesene, benzyl benzoate, humulene and caryophyllene, while in those of Comoros, cinnamyl acetate, benzyl salicylate, trans-farnesyl acetate and α-farnesene are found to be higher. It is possible to verify the origin and grade of an unspecified source of ylang-ylang essential oil from the biplot of the 22 compounds

Flavour and Fragrance Journal published new progress about Gas chromatography. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Quality Control of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Zhan-Ku published the artcileEthanol and formic acid as synergistic solvents for converting lignite to platform chemicals, Recommanded Product: Ethyl nonanoate, the main research area is ethanol formic acid phenol ester lignite ethanolysis.

Formic acid (FA)-catalyzed ethanolysis of Xilinguole lignite (XL) was carried out with FA to ethanol ratio of 0-1:6 mL/mL at 220-320 °C. The optimal conditions were determined to be 300 °C and FA to ethanol ratio of 1:10 mL/mL based on ethanol-soluble portion (ESP) yield and the maximum ESP yield is 48.0 wt%. Both carbon balance and Fourier transform IR spectrometric analyses confirm that FA and ethanol involved in ethanolysis of XL. Three major platform chems., i.e., arenes, phenols, and esters, were identified in ESPs by gas chromatog./mass spectrometry. The yields of arenes and phenols significantly increased from 15.67 to 58.33 mg/g and 36.02 to 168.44 mg/g with adding FA to ethanolysis of XL, resp. The alkyl groups of arenes and phenols are more abundant in ESPs from FA-catalyzed ethanolysis of XL. The results suggest that FA enhanced hydrogenolysis of aryl ethers and alkylation of ethanol during XL ethanolysis. Hydrogen generated from FA hindered dehydrogenation of ethanol, resulting in the decrease of ethanol-derived esters. Ethanol acts as in-situ hydrogen donor for hydrogenolysis and reactant for alkylation, aldol condensation, and esterification, while FA serves as acid catalyst and in-situ hydrogen donor for hydrogenolysis. Addnl., possible pathways for FA-catalyzed ethanolysis of XL were proposed.

Fuel published new progress about Aldol condensation. 123-29-5 belongs to class esters-buliding-blocks, name is Ethyl nonanoate, and the molecular formula is C11H22O2, Recommanded Product: Ethyl nonanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Zhan-Ku published the artcileEthanol and formic acid as synergistic solvents for converting lignite to platform chemicals, Formula: C7H12O3, the main research area is ethanol formic acid phenol ester lignite ethanolysis.

Formic acid (FA)-catalyzed ethanolysis of Xilinguole lignite (XL) was carried out with FA to ethanol ratio of 0-1:6 mL/mL at 220-320 °C. The optimal conditions were determined to be 300 °C and FA to ethanol ratio of 1:10 mL/mL based on ethanol-soluble portion (ESP) yield and the maximum ESP yield is 48.0 wt%. Both carbon balance and Fourier transform IR spectrometric analyses confirm that FA and ethanol involved in ethanolysis of XL. Three major platform chems., i.e., arenes, phenols, and esters, were identified in ESPs by gas chromatog./mass spectrometry. The yields of arenes and phenols significantly increased from 15.67 to 58.33 mg/g and 36.02 to 168.44 mg/g with adding FA to ethanolysis of XL, resp. The alkyl groups of arenes and phenols are more abundant in ESPs from FA-catalyzed ethanolysis of XL. The results suggest that FA enhanced hydrogenolysis of aryl ethers and alkylation of ethanol during XL ethanolysis. Hydrogen generated from FA hindered dehydrogenation of ethanol, resulting in the decrease of ethanol-derived esters. Ethanol acts as in-situ hydrogen donor for hydrogenolysis and reactant for alkylation, aldol condensation, and esterification, while FA serves as acid catalyst and in-situ hydrogen donor for hydrogenolysis. Addnl., possible pathways for FA-catalyzed ethanolysis of XL were proposed.

Fuel published new progress about Aldol condensation. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Formula: C7H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Najar, Basma published the artcileChemical Composition and in Vitro Cytotoxic Screening of Sixteen Commercial Essential Oils on Five Cancer Cell Lines, Application of Benzyl acetate, the main research area is essential oil composition cytotoxic screening; K562; MCF7; MDA-MB-231; SHSY-5Y; T47D; cytotoxicity.

The in vitro cytotoxic activity on human cancer cell lines of sixteen com. EOs such as Aloysia citriodora, Boswellia sacra, Boswellia serrata, Cinnamomum zeylanicum, Cistus ladanifer, Citrus × aurantium, Citrus limon, Citrus sinensis, Cymbopogon citratus, Foeniculum vulgare, Illicium verum, Litsea cubeba, Satureja montana, Syzygium aromaticum, Thymus capitatus and Thymus vulgaris was performed using the MTT reduction assay. The screening was carried out on human cancer cells of breast adenocarcinoma (MCF7, T47D and MDA-MB-231), chronic myelogenous erythroleukemia (K562) and neuroblastoma cell lines (SH-SY5Y). C. zeylanicum and L. cubeba EOs were the most active on almost all the cell lines studied and thus could be promising as an anticancer agent. These two species showed a difference in their composition even though they belong to the Lauraceae family. Almost 57% of the true cinnamon composition was made of (E)-cinnamaldehyde, while L. cubeba showed citral as the major compound (68.9%). The K562 cells were the most sensitive to these oils with an IC50 ranging from 5.2 parts-per million (ppm) (C. zeylanicum) to 11.1 ppm (L. cubeba). The latter oil also showed an important cytotoxicity on MDA-MB-231 (13.4 ppm).

Chemistry & Biodiversity published new progress about Aloysia citriodora. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Application of Benzyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wu, Hongguo published the artcileHot water-promoted catalyst-free reductive cycloamination of (bio-)keto acids with HCOONH4 toward cyclic amides, Recommanded Product: Ethyl 4-oxopentanoate, the main research area is keto acid ammonium formate tandem reductive cycloamination; cyclic amide preparation.

HCOONH4 was demonstrated to be capable of acting as both hydrogen and nitrogen source in the absence of any catalyst and additive for the reductive cycloamination of bio-based levulinic acid (LA) to 5-methyl-2-pyrrolidone (MPL) with more than 90% in just 60 min at 180°. Pressurized hot water remarkably enabled the reaction efficiency and rate by promoting the hydrolysis of HCOONH4 to liberated ammonia and formic acid for the cascade reactions and this catalyst-free protocol was also applicable to the efficient synthesis of various cyclic amides from relevant keto acids. Moreover, the reaction pathways were investigated by conducting deuterium-labeling experiments and kinetic studies of selected reactions.

Journal of Supercritical Fluids published new progress about Amidation kinetics. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Recommanded Product: Ethyl 4-oxopentanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics