Category: esters-buliding-blocks

Wan, Feifei published the artcileThe transfer hydrogenation of high concentration levulinic acid to γ-valerolactone catalyzed by glucose phosphate carbamide zirconium, Quality Control of 539-88-8, the main research area is glucose phosphate carbamide zirconium levulinic acid transfer hydrogenation catalyst; gamma valerolactone turnover frequency.

Zr-Based catalysts have been extensively applied in Meerwein-Ponndorf-Verley type catalytic transfer hydrogenation (CTH) reactions, but they are easily deactivated in the CTH conversion of high concentrations of levulinic acid (LA) to γ-valerolactone (γ-GVL). This work discloses that by using cheap glucose and ZrCl4 as two main raw materials, glucose phosphate carbamide zirconium (GluPC-Zr) is easily synthesized at large scale and low cost via a simple two-step conversion. The constructed GluPC-Zr has enhanced Lewis acid-base properties and good porosity, thus exhibiting outstanding activity for the CTH reactions of LA or its esters with isopropanol (IPA), providing 95-98% γ-GVL yields. Because of the excellent esterification performance of the introduced acidic phosphate groups, GluPC-Zr also works well at high LA concentrations, achieving a much higher turnover frequency (TOF, 8.2 mmol γ-GVL per g catalyst per h) than previously reported Zr-based catalysts (TOF, 0.2-2.4). And it shows excellent reusability in the reaction of LA with IPA, still providing ca. 95% γ-GVL yield after the seventh cycle run. This work provides a preferential esterification strategy for LA to hamper catalyst deactivation, which is of special significance for the large-scale production of γ-GVL from biomass-derived LA and a low-cost GluPC-Zr catalyst.

Green Chemistry published new progress about Bronsted acidity. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Quality Control of 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

He, Jian published the artcileDual acidic mesoporous KIT silicates enable one-pot production of γ-valerolactone from biomass derivatives via cascade reactions, Recommanded Product: Ethyl 4-oxopentanoate, the main research area is zirconium silica catalyst biomass derivative valerolactone one pot synthesis; morphol physicochem property.

γ-Valerolactone (GVL) is an interesting bio-based platform mol. that is utilized as green solvent and a versatile building block for the synthesis of bio-fuels and chems. Herein, an investigation on the efficient production of GVL from biomass-based carbonyl compounds such as furfural, levulinic acid, and its esters using 2-propanol as H-donor and solvent over stable Zr-incorporated mesoporous silica (KIT-5) catalysts was presented. Both Lewis and Bronsted acid sites were generated by the introduction of Zr into KIT-5, and the acid d. of the resulting Zr-KIT-5(Si/Zr) could be controlled by simply adjusting Si/Zr molar ratio. Among these bifunctional catalysts, Zr-KIT-5(10) showed superior catalytic performance in the production of GVL (>91% selectivity) from biomass-derived carboxides (ca. 94% conversion), which was demonstrated to pos. correlate with its large amount of acidic sites and facile access of active sites to interconnected pores. Moreover, the spent catalyst held about 90% of its original activity in the sixth run. Due to the presence of Bronsted and Lewis dual acidic sites in Zr-KIT-5, the direct conversion of furfural to GVL was also permitted in a single pot via tandem reactions involving hydrogenation, ring-opening, secondary hydrogenation, and subsequent cyclization.

Renewable Energy published new progress about Bronsted acidity. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Recommanded Product: Ethyl 4-oxopentanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Garcia, Margarita published the artcileSequential Non-Saccharomyces and Saccharomyces cerevisiae fermentations to reduce the alcoholcontent in wine, COA of Formula: C6H12O3, the main research area is Saccharomyces Wickerhamomyces Meyerozyma Metschnikowia fermentation alc reduction wine.

Over the last decades, the average alc. content of wine has increased due to climate change and consumer preferences for particular wine styles that resulted in increased grape sugar levels at harvest. Therefore, alc. reduction is a current challenge in the winemaking industry. Among several strategies under study, the use of non-conventional yeasts in combination with Saccharomyces cerevisiae plays an important role for lowering ethanol production in wines nowadays. In the present work, 33 native non-Saccharomyces strains were assayed in sequential culture with a S. cerevisiae wine strain to determine their potential for reducing the alc. content in Malvar white wines. Four of the non-Saccharomyces strains (Wickerhamomyces anomalus 21A-5C, Meyerozyma guilliermondii CLI 1217, and two Metschnikowia pulcherrima (CLI 68 and CLI 460)) studied in sequential combination with S. cerevisiae CLI 889 were best able to produce dry wines with decreased alc. proportion in comparison with one that was inoculated only with S. cerevisiae. These sequential fermentations produced wines with between 0.8% (volume/volume) and 1.3% (volume/volume) lower ethanol concentrations in Malvar wines, showing significant differences compared with the control. In addition, these combinations provided favorable oenol. characteristics to wines such as high glycerol proportion, volatile higher alcs., and esters with fruity and sweet character.

Fermentation published new progress about Candida stellata. 5405-41-4 belongs to class esters-buliding-blocks, name is Ethyl 3-hydroxybutanoate, and the molecular formula is C6H12O3, COA of Formula: C6H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Xiaoyu published the artcileHighly efficient solar evaporator based on a hydrophobic association hydrogel, HPLC of Formula: 142-90-5, the main research area is efficient solar evaporator based hydrophobic association hydrogel.

Recently, concerns over water scarcity are on the rise, leading to growing research interest in advanced water purification methods. Solar water purification, which utilizes sustainable energy to sep. water impurities and water through evaporation, is emerging as a promising strategy for clean water production Here, we report a novel solar evaporator based on a carbon nanotube composite polyacrylamide hydrogel (CAH) with a high solar evaporation rate of 4.3 kg·m-2·h-1 under 1 sun irradiation (1 kW·m-2). Such a highly efficient solar evaporator is achieved by introducing solar absorbers (carboxyl multi-walled carbon nanotubes) in the hydrophilic skeleton (polyacrylamide) of hydrophobic association hydrogel. More importantly, the self-healing properties endowed by hydrophobic association also provide a simple fabrication route of double-layer hydrogel-based solar evaporator. By a proper double-layer structure design, the solar evaporation rate of CAH can be further increased to a record high value of 5.1 kg·m-2·h-1. In addition, the CAH can effectively remove salt ions and heavy metal ions in water. The extraordinary performance along with the simple and low-cost fabrication route of CAH offers possibilities for practical ultra-fast solar water purification under natural sunlight. Our solar evaporator can achieve long-term ultra-fast water purification by using sustainable solar energy as the only energy resource.

ACS Sustainable Chemistry & Engineering published new progress about Carbon nanotubes. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, HPLC of Formula: 142-90-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Qin, Zhihui published the artcileCarbon nanotubes/hydrophobically associated hydrogels as ultrastretchable, highly sensitive, stable strain, and pressure sensors, Related Products of esters-buliding-blocks, the main research area is carbon nanotube polyacrylamide conductive hydrogel skin like pressure sensor; carbon nanotubes; high strength; hydrophobic association; nanocomposite hydrogel; skin-like sensor.

Conductive hydrogels have become one of the most promising materials for skin-like sensors because of their excellent biocompatibility and mech. flexibility. However, the limited stretchability, low toughness, and fatigue resistance lead to a narrow sensing region and insufficient durability of the hydrogel-based sensors. In this work, an extremely stretchable, highly tough, and anti-fatigue conductive nanocomposite hydrogel is prepared by integrating hydrophobic carbon nanotubes (CNTs) into hydrophobically associated polyacrylamide (HAPAAm) hydrogel. In this conductive hydrogel, amphiphilic sodium dodecyl sulfate was used to ensure uniform dispersion of CNTs in the hydrogel network, and hydrophobic interactions between the hydrogel matrix and the CNT surface formed, greatly improving the mech. properties of the hydrogel. The obtained CNTs/HAPAAm hydrogel showed excellent stretchability (ca. 3000%), toughness (3.42 MJ m-3), and great anti-fatigue property. Moreover, it exhibits both high tensile strain sensitivity in the wide strain ranges (gauge factor = 4.32, up to 1000%) and high linear sensitivity (0.127 kPa-1) in a large-pressure region within 0-50 kPa. The CNTs/HAPAAm hydrogel-based sensors can sensitively and stably detect full-range human activities (e.g., elbow rotation, finger bending, swallowing motion, and pronouncing) and handwriting, demonstrating the CNTs/HAPAAm hydrogel’s potential as the wearable strain and pressure sensors for flexible devices.

ACS Applied Materials & Interfaces published new progress about Carbon nanotubes. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Myasoedova, Yu. V. published the artcileHydrazides of Organic Acids in the Transformations of the Peroxide Products of Non-1-ene Ozonolysis, Synthetic Route of 111-11-5, the main research area is acylhydrazone preparation chemoselectivity; peroxide product acid hydrazide aprotic solvent chemoselective reduction; nonene ozone ozonolysis.

The reaction of hydrazides of alicyclic capric and aromatic benzoic and p-hydroxybenzoic acids with the peroxide product of non-1-ene ozonolysis was studied. Capric acid hydrazide exhibited the strongest reducing properties in aprotic solvents (methylene chloride, THF) and led to chemoselective and high-yield (�80%) formation of corresponding acylhydrazone. P-Hydroxybenzoic acid hydrazide formed a similar derivative with a yield of 67% only in THF.

Russian Journal of Organic Chemistry published new progress about Chemoselectivity. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Synthetic Route of 111-11-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Russo, Barbara published the artcileInterventions for healthcare professionals taking care of COVID-19 patients (beyond vaccines). A systematic review, Computed Properties of 55981-09-4, the main research area is intervention healthcare COVID 19 patient.

Since the first declared case of novel coronavirus disease 2019 (COVID-19) infection, more than 8 millions of individuals as of June 20, 2020, have been infected worldwide, with about 454.000 reported deaths. This disease is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), similar to severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). Currently, no vaccine or proven effective prophylactic treatment is available. Despite the measures to prevent contamination, many cases of infections and deaths have been observed among the healthcare professionals (HCPs). Furthermore, the high number of severe patients to manage, the increased workload, the shortage or inadequacy of personal protective equipment (PPE), are possible source of phys. and psychol. stress. All these factors may contribute to the shortage of personnel working in healthcare facilities, with potential detrimental impact on health system. It becomes, therefore, crucial to identify interventions to support and protect HCPs. A summary of preventative or therapeutic interventions specifically designed for healthcare workers facing with COVID-19 pandemic, could help to drive future research in the field.

Coronavirus Free Access Collection published new progress about Chinese medicine. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, Computed Properties of 55981-09-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pinto, Joana published the artcileCharacterization of chemical compounds susceptible to be extracted from cork by the wine using GC-MS and 1H NMR metabolomic approaches, Application In Synthesis of 123-29-5, the main research area is wine maturation cork extractable compound geog origin; 1-Terpinen-4-ol (PubChem CID: 11230); Camphene (PubChem CID: 6616); Castalagin (PubChem CID: 168165); Cork; Friedelin (PubChem CID: 91472); GC-MS; Geographical origin; Metabolomics; NMR spectroscopy; Polyphenols; Pyrogallol (PubChem CID: 1057); Quinic acid (PubChem CID: 6508); Sitost-4-en-3-one (PubChem CID: 5484202); Vescalagin (PubChem CID: 5458626); Volatile compounds; o-Cymene (PubChem CID: 10703); trans-3-Pinanone (PubChem CID: 11038); trans-Squalene (PubChem CID: 638072).

This work presents a metabolomic study of cork by GC-MS and 1H-NMR spectroscopy to characterize compounds susceptible to be extracted from cork by the wine in an attempt to find a relationship between the content of these compounds and the geog. origin of cork. Cork from eleven geog. regions was studied, five from Portugal and six from Spain. Unsupervised pattern recognition techniques unveiled three main clusters of regions according to their chem. similarity but not related with geog. proximity. Nineteen compounds were found to be responsible for the clusters, including terpenes (trans-squalene, friedelin, camphene, trans-3-pinanone, 1-terpinen-4-ol, two sesquiterpenes), polyphenols (vescalagin, castalagin), among others (pyrogallol, glucosan, sitost-4-en-3-one, o-cymene, quinic acid, five unknowns). These preliminary results unveiled the potential for a more efficient selection of cork planks for stoppers production based on the compounds susceptible to be extracted from cork by the wine.

Food Chemistry published new progress about Cluster analysis. 123-29-5 belongs to class esters-buliding-blocks, name is Ethyl nonanoate, and the molecular formula is C11H22O2, Application In Synthesis of 123-29-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mosayebnia, Mona published the artcileIn silico prediction of SARS-CoV-2 main protease and polymerase inhibitors: 3D-Pharmacophore modelling, Application In Synthesis of 55981-09-4, the main research area is tegobuvir SARS CoV2 protease polymerase inhibitor pharmacophore modeling; RdRp; SARS-CoV-2; docking study; pharmacophore modelling; protease 3Clpro.

The outbreak of the second severe acute respiratory syndrome coronavirus (SARS-CoV-2) known as COVID-19 has caused global concern. No effective vaccine or treatment to control the virus has been approved yet. Social distancing and precautionary protocols are still the only way to prevent person-to-person transmission. We hope to identify anti-COVID-19 activity of the existing drugs to overcome this pandemic as soon as possible. The present study used HEX and AutoDock Vina softwares to predict the affinity of about 100 medicinal structures toward the active site of 3-chymotrypsin-like protease (3Clpro) and RNA-dependent RNA polymerase (RdRp), sep. Afterwards, MOE software and the pharmacophore-derived query methodol. were employed to determine the pharmacophore model of their inhibitors. Tegobuvir () and compound showed the best binding affinity toward RdRp and 3Clpro of SARS-CoV-2 in silico, resp. Tegobuvir -previously applied for hepatitis C virus- formed highly stable complex with uncommon binding pocket of RdRp (E total: -707.91 Kcal/mol) in silico. In addition to compound, tipranavir () and atazanavir () as FDA-approved HIV protease inhibitors were tightly interacted with the active site of SARS-CoV-2 main protease as well. Based on pharmacophore modeling, a good structural pattern for potent candidates against SARS-CoV-2 main enzymes is suggested. Re-tasking or taking inspiration from the structures of tegobuvir and tipranavir can be a proper approach toward coping with the COVID-19 in the shortest possible time and at the lowest cost.

Journal of Biomolecular Structure and Dynamics published new progress about Computer program. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, Application In Synthesis of 55981-09-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Roppongi, Takao published the artcileSolubility and mass transfer coefficient of oxygen through gas- and water-lipid interfaces, Recommanded Product: Methyl octanoate, the main research area is gas water lipid interface oxygen solubility mass transfer; Henry’s constant; fatty acid; mass transfer coefficient; oxidation; vegetable oil.

The solubility of oxygen and its transfer rate to the lipid phase play important roles in lipid oxidation, which affects the taste and safety of lipid-containing foods. In this study, we measured the Henry’s constants (solubility) of oxygen for fatty acids, fatty acid esters, and triacylglycerols (TAGs; vegetable oils), as well as the mass transfer coefficients of oxygen at the gas- and water-lipid interfaces. The constants and coefficients were estimated by analyzing the change over time in the oxygen partial pressure or concentration in the closed container based on the mass balance equations of oxygen in the gas and liquid phases. The constant for water obtained by the method used in this study was in agreement with the previously reported value to confirm the validity of the method. The constants for lipids depended on the lipid type, and were higher in the order of fatty acid ester, fatty acid, and TAG. That is, the solubility of oxygen decreased in this order. For all lipids, the constant increased as the number of carbon atoms in the fatty acid chain increased. The constants for fatty acids and their esters were linearly correlated with the enthalpies of evaporation of the lipids. The mass transfer coefficients of oxygen at the gas-liquid interface were on the order of 10-5 m/s for water and Me dodecanoate and of 10-6 m/s for TAG (rapeseed oil). The coefficient at the water-lipid interface was on the order of 10-6 m/s. The Henry’s constants (solubility) and transfer rate of oxygen to the lipid phase, fatty acids, fatty acid esters, and triacylglycerols (TAG) were measured. The lipids solubilized three to five times more oxygen than water, and mass transfer rate of oxygen at gas- and water-lipid interfaces were almost same. The constants for fatty acids and fatty acid esters were linearly correlated to their enthalpies of evaporation, and this correlation is expected to be useful for estimating the Henry’s constants for other fatty acids and their esters.

Journal of Food Science published new progress about Cottonseed (oil). 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Recommanded Product: Methyl octanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics